Click here to switch to the map view.

The map label for this gene is katA

Identifier: 255767204

GI number: 255767204

Start: 959535

End: 960986

Strand: Reverse

Name: katA

Synonym: BSU08820

Alternate gene names: 255767204

Gene position: 960986-959535 (Counterclockwise)

Preceding gene: 16077954

Following gene: 255767203

Centisome position: 22.8

GC content: 45.59

Gene sequence:

>1452_bases
ATGAGTTCAAATAAACTGACAACTAGCTGGGGCGCTCCGGTTGGAGATAATCAAAACTCAATGACTGCCGGTTCTCGCGG
ACCAACTTTAATTCAAGATGTACATTTACTCGAAAAATTGGCCCATTTCAACCGAGAACGTGTTCCTGAACGTGTTGTTC
ACGCCAAAGGAGCAGGCGCACACGGATATTTTGAAGTGACAAACGACGTAACAAAATACACGAAAGCCGCTTTCCTTTCT
GAAGTCGGCAAACGCACACCGTTGTTCATCCGTTTCTCAACAGTTGCCGGTGAACTTGGCTCTGCTGACACAGTTCGCGA
CCCGCGCGGATTTGCTGTTAAATTTTATACTGAAGAAGGAAACTACGACATCGTCGGCAACAATACGCCTGTATTCTTTA
TCCGCGATGCGATTAAGTTCCCTGATTTCATCCATACACAAAAAAGAGATCCAAAAACACACCTGAAAAACCCTACGGCT
GTATGGGATTTCTGGTCACTTTCACCAGAGTCACTGCACCAAGTGACAATCCTGATGTCTGACCGCGGAATTCCTGCGAC
ACTTCGCCACATGCACGGCTTCGGAAGCCATACATTCAAATGGACAAATGCCGAAGGCGAAGGCGTATGGATTAAATATC
ACTTTAAAACAGAACAAGGCGTGAAAAACCTTGATGTCAATACGGCAGCAAAAATTGCCGGTGAAAACCCTGATTACCAT
ACAGAAGACCTTTTCAACGCAATCGAAAACGGTGATTATCCTGCATGGAAACTATATGTGCAAATCATGCCTTTAGAAGA
TGCAAATACGTACCGTTTCGATCCGTTTGATGTCACAAAAGTTTGGTCTCAAAAAGACTACCCGTTAATCGAGGTCGGAC
GCATGGTTCTAGACAGAAATCCGGAAAACTACTTTGCAGAGGTAGAACAAGCGACATTTTCACCTGGAACCCTCGTGCCT
GGTATTGATGTTTCACCGGATAAAATGCTTCAAGGTCGACTTTTTGCTTATCATGATGCACACCGCTACCGTGTCGGTGC
AAACCATCAAGCGCTGCCAATCAACCGCGCACGCAACAAAGTAAACAATTATCAGCGTGATGGGCAAATGCGTTTTGATG
ATAACGGCGGCGGATCTGTGTATTACGAGCCTAACAGCTTCGGCGGTCCAAAAGAGTCACCTGAGGATAAGCAAGCAGCA
TATCCGGTACAAGGTATCGCTGACAGCGTAAGCTACGATCACTACGATCACTACACTCAAGCCGGCGATCTGTATCGTTT
AATGAGTGAAGATGAACGTACCCGCCTTGTTGAAAATATCGTTAATGCCATGAAGCCGGTAGAAAAAGAAGAAATCAAGC
TGCGCCAAATCGAGCACTTCTACAAAGCGGATCCTGAATACGGAAAACGCGTGGCAGAAGGCCTTGGATTGCCGATTAAA
AAAGATTCTTAA

Upstream 100 bases:

>100_bases
TCGATTAATAGAGATAACTATTTTATAATAATTATAAAATAATATTGACTTTTTACTTAGAGATGATATTATGTTCTTAT
AAATTCCAAGAGGTGATAAC

Downstream 100 bases:

>100_bases
TGGAGAAATGCAAAAACCCGTTGTAGTCAGCGGGTTTTTTTATATTTAGTTACACATTGCGTATGCTTCTCATCAATCTT
CATATAAATTTCTTCCATGA

Product: vegetative catalase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSSNKLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLS
EVGKRTPLFIRFSTVAGELGSADTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPKTHLKNPTA
VWDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNAEGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
TEDLFNAIENGDYPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLDRNPENYFAEVEQATFSPGTLVP
GIDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRARNKVNNYQRDGQMRFDDNGGGSVYYEPNSFGGPKESPEDKQAA
YPVQGIADSVSYDHYDHYTQAGDLYRLMSEDERTRLVENIVNAMKPVEKEEIKLRQIEHFYKADPEYGKRVAEGLGLPIK
KDS

Sequences:

>Translated_483_residues
MSSNKLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLS
EVGKRTPLFIRFSTVAGELGSADTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPKTHLKNPTA
VWDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNAEGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
TEDLFNAIENGDYPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLDRNPENYFAEVEQATFSPGTLVP
GIDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRARNKVNNYQRDGQMRFDDNGGGSVYYEPNSFGGPKESPEDKQAA
YPVQGIADSVSYDHYDHYTQAGDLYRLMSEDERTRLVENIVNAMKPVEKEEIKLRQIEHFYKADPEYGKRVAEGLGLPIK
KDS
>Mature_482_residues
SSNKLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVTKYTKAAFLSE
VGKRTPLFIRFSTVAGELGSADTVRDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPKTHLKNPTAV
WDFWSLSPESLHQVTILMSDRGIPATLRHMHGFGSHTFKWTNAEGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYHT
EDLFNAIENGDYPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLDRNPENYFAEVEQATFSPGTLVPG
IDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRARNKVNNYQRDGQMRFDDNGGGSVYYEPNSFGGPKESPEDKQAAY
PVQGIADSVSYDHYDHYTQAGDLYRLMSEDERTRLVENIVNAMKPVEKEEIKLRQIEHFYKADPEYGKRVAEGLGLPIKK
DS

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family

Homologues:

Organism=Homo sapiens, GI4557014, Length=472, Percent_Identity=57.2033898305085, Blast_Score=567, Evalue=1e-162,
Organism=Escherichia coli, GI48994891, Length=497, Percent_Identity=44.2655935613682, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71998444, Length=468, Percent_Identity=54.7008547008547, Blast_Score=540, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=53.6016949152542, Blast_Score=526, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=53.3898305084746, Blast_Score=525, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6320462, Length=385, Percent_Identity=53.2467532467532, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321525, Length=507, Percent_Identity=40.4339250493097, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI17981717, Length=482, Percent_Identity=54.149377593361, Blast_Score=546, Evalue=1e-155,
Organism=Drosophila melanogaster, GI19920968, Length=476, Percent_Identity=48.5294117647059, Blast_Score=489, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CATA_BACSU (P26901)

Other databases:

- EMBL:   M80796
- EMBL:   Z82044
- EMBL:   AL009126
- PIR:   JH0532
- RefSeq:   NP_388762.2
- ProteinModelPortal:   P26901
- SMR:   P26901
- PeroxiBase:   4082
- EnsemblBacteria:   EBBACT00000004087
- GeneID:   939240
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU08820
- NMPDR:   fig|224308.1.peg.881
- GenoList:   BSU08820
- GeneTree:   EBGT00050000002743
- HOGENOM:   HBG339355
- ProtClustDB:   CLSK886919
- BioCyc:   BSUB:BSU08820-MONOMER
- BRENDA:   1.11.1.6
- GO:   GO:0005737
- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- Gene3D:   G3DSA:2.40.180.10
- PANTHER:   PTHR11465
- PRINTS:   PR00067

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; SSF56634 Catalase_N

EC number: =1.11.1.6

Molecular weight: Translated: 54792; Mature: 54661

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00437 CATALASE_1; PS00438 CATALASE_2; PS51402 CATALASE_3

Important sites: ACT_SITE 54-54 ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNKLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGA
CCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHCHHHHHHCCCCCC
HGYFEVTNDVTKYTKAAFLSEVGKRTPLFIRFSTVAGELGSADTVRDPRGFAVKFYTEEG
CCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECC
NYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPKTHLKNPTAVWDFWSLSPESLHQVTILMS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCHHHCCCCCEEEEECCCCHHHHEEEEEEEE
DRGIPATLRHMHGFGSHTFKWTNAEGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
CCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHCCCCCCCCC
TEDLFNAIENGDYPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLDRN
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCC
PENYFAEVEQATFSPGTLVPGIDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRARNK
CHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEECCCEEEECCCCCCCCHHHHHHH
VNNYQRDGQMRFDDNGGGSVYYEPNSFGGPKESPEDKQAAYPVQGIADSVSYDHYDHYTQ
HHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCHHHHHH
AGDLYRLMSEDERTRLVENIVNAMKPVEKEEIKLRQIEHFYKADPEYGKRVAEGLGLPIK
HHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
KDS
CCC
>Mature Secondary Structure 
SSNKLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGA
CCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHCHHHHHHCCCCCC
HGYFEVTNDVTKYTKAAFLSEVGKRTPLFIRFSTVAGELGSADTVRDPRGFAVKFYTEEG
CCEEEECHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECC
NYDIVGNNTPVFFIRDAIKFPDFIHTQKRDPKTHLKNPTAVWDFWSLSPESLHQVTILMS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCHHHCCCCCEEEEECCCCHHHHEEEEEEEE
DRGIPATLRHMHGFGSHTFKWTNAEGEGVWIKYHFKTEQGVKNLDVNTAAKIAGENPDYH
CCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHHHCCCCCCCCC
TEDLFNAIENGDYPAWKLYVQIMPLEDANTYRFDPFDVTKVWSQKDYPLIEVGRMVLDRN
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHCCC
PENYFAEVEQATFSPGTLVPGIDVSPDKMLQGRLFAYHDAHRYRVGANHQALPINRARNK
CHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEEECCCEEEECCCCCCCCHHHHHHH
VNNYQRDGQMRFDDNGGGSVYYEPNSFGGPKESPEDKQAAYPVQGIADSVSYDHYDHYTQ
HHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCHHHHHH
AGDLYRLMSEDERTRLVENIVNAMKPVEKEEIKLRQIEHFYKADPEYGKRVAEGLGLPIK
HHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
KDS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1756979; 9202460; 9384377; 8180695; 10658653