Click here to switch to the map view.

The map label for this gene is ycgH

Identifier: 255767088

GI number: 255767088

Start: 336092

End: 337432

Strand: Reverse

Name: ycgH

Synonym: BSU03110

Alternate gene names: 255767088

Gene position: 337432-336092 (Counterclockwise)

Preceding gene: 255767090

Following gene: 255767085

Centisome position: 8.0

GC content: 46.76

Gene sequence:

>1341_bases
ATGAGCCAAACAAAAAAAGACCAGCCAAAAGGGAATCTGGCTTGGTGGCAGCTGTCACTGATCGGAGTCGGCTGCACGAT
TGGAACAGGCTTCTTTCTCGGTTCCAGCATCGCAATTGTAAAAAGCGGTTTTTCCGTTCTCCTTTCATTTCTGATCGCAG
GGATCGGTACGTATTTTGTCTTTGAACAGCTCGCCAAGCTATCGGCGAAGCAGCCGGAAAAGGGCTCGTTTTGTGCGTAT
GCCCGAAAAGCATTCGGCAAATGGGCAGGCTTCAGCAACGGCTGGGTGTACTGGACATCAGAAATGCTGATTACCGGAAG
CCAGCTGACAGCCATTTCGCTCTTTACGAAGCATTGGTTTCCTCAAGTGCCGCTATGGGTGTTTGCCTCAATCTACGCAG
TACTTGGGCTCCTTATTATTTTCACCGGCCTGTCCGTCTTTGAAAAAACAGAAAACGTGCTGGCAGTCATTAAAACAGCT
GCTATTTTTATGTTTATTGTCATTGCCATCCTGGCTTTATGCGGTATCCTGTCCGGCGGAAATCATGGCATACATGTTCC
AAATAAGACGAGTGAGTTTTTCCCATACGGCGCCATGGGGCTGTGGACAGGTTTAATCTACGCGTTTTACGCTTTTGGCG
GAATTGAGGTCATGGGGCTGATGGCGGTTCACTTAAAAAAACCTGAGGAAGCGTCTAAATCAGGGAAACTGATGCTGGCG
ACGCTGGCGATTATTTATATCATTTCAATCGGGCTTGCTCTGCTTTTGGTTCCGTTACACACGTTTACTGAACAGGACAG
TCCGTTCATTACGTCATTAAAAGGATATAACCTTGAGATCATCCTTGATATATTTAACGGGATTTTCATCATCGCAGGGT
TCTCGACCCTTGTCGCTTCGCTATTTGCGGTTACGACATTGCTTTGTACAATGGCTGATGACGGCGACGCGCCGAAATGC
TTTACTCTAAAGGAAGGCAAAAAAATATGCTGGCCGGCACTTGGGCTGACGTTTGCGGGGCTTGTCCTCTCCATTATTTT
GTCGTTAGTGCTGCCTAAAAACATTTATGAGCATATGACAACAGCTGCGGGGCTTATGCTTTTATACACTTGGCTGTTTA
TCCTGTTCTCCAGCAAAAAGCTGACTGATCCCGAGGGCATGGGAAAAACGCAAATTTATTTAGCGATGGTTCTGATTGCT
GCAGCTGTGTCCGGTACATTGTTTGAAAAATCAAGCCGGCCCGGTTTTTTCGTCAGCATAGGTTTTCTCGTGATTATCGC
CATCGTTACCATGATCTATCAAAAAAAGCAGGGTCATAAAGATCGCCCTGCCAGTCCTTGA

Upstream 100 bases:

>100_bases
CGTCTGCTTCCTTCTCCATGTAAAAAGAGGCAAAAATCCGATGTATATAAGCTTTGGACAGATCACAATCTAACCTTAGA
TAAAAGGGGTTGAATAAATA

Downstream 100 bases:

>100_bases
TTTATTTCATTTTGTTGAACATGTTCTTTAAATAAGAAAACGGGCACTTCGATACCTGTTTTTCGTCATCACGGAGGAAA
TACTGCTTCCATTCACGATT

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSQTKKDQPKGNLAWWQLSLIGVGCTIGTGFFLGSSIAIVKSGFSVLLSFLIAGIGTYFVFEQLAKLSAKQPEKGSFCAY
ARKAFGKWAGFSNGWVYWTSEMLITGSQLTAISLFTKHWFPQVPLWVFASIYAVLGLLIIFTGLSVFEKTENVLAVIKTA
AIFMFIVIAILALCGILSGGNHGIHVPNKTSEFFPYGAMGLWTGLIYAFYAFGGIEVMGLMAVHLKKPEEASKSGKLMLA
TLAIIYIISIGLALLLVPLHTFTEQDSPFITSLKGYNLEIILDIFNGIFIIAGFSTLVASLFAVTTLLCTMADDGDAPKC
FTLKEGKKICWPALGLTFAGLVLSIILSLVLPKNIYEHMTTAAGLMLLYTWLFILFSSKKLTDPEGMGKTQIYLAMVLIA
AAVSGTLFEKSSRPGFFVSIGFLVIIAIVTMIYQKKQGHKDRPASP

Sequences:

>Translated_446_residues
MSQTKKDQPKGNLAWWQLSLIGVGCTIGTGFFLGSSIAIVKSGFSVLLSFLIAGIGTYFVFEQLAKLSAKQPEKGSFCAY
ARKAFGKWAGFSNGWVYWTSEMLITGSQLTAISLFTKHWFPQVPLWVFASIYAVLGLLIIFTGLSVFEKTENVLAVIKTA
AIFMFIVIAILALCGILSGGNHGIHVPNKTSEFFPYGAMGLWTGLIYAFYAFGGIEVMGLMAVHLKKPEEASKSGKLMLA
TLAIIYIISIGLALLLVPLHTFTEQDSPFITSLKGYNLEIILDIFNGIFIIAGFSTLVASLFAVTTLLCTMADDGDAPKC
FTLKEGKKICWPALGLTFAGLVLSIILSLVLPKNIYEHMTTAAGLMLLYTWLFILFSSKKLTDPEGMGKTQIYLAMVLIA
AAVSGTLFEKSSRPGFFVSIGFLVIIAIVTMIYQKKQGHKDRPASP
>Mature_445_residues
SQTKKDQPKGNLAWWQLSLIGVGCTIGTGFFLGSSIAIVKSGFSVLLSFLIAGIGTYFVFEQLAKLSAKQPEKGSFCAYA
RKAFGKWAGFSNGWVYWTSEMLITGSQLTAISLFTKHWFPQVPLWVFASIYAVLGLLIIFTGLSVFEKTENVLAVIKTAA
IFMFIVIAILALCGILSGGNHGIHVPNKTSEFFPYGAMGLWTGLIYAFYAFGGIEVMGLMAVHLKKPEEASKSGKLMLAT
LAIIYIISIGLALLLVPLHTFTEQDSPFITSLKGYNLEIILDIFNGIFIIAGFSTLVASLFAVTTLLCTMADDGDAPKCF
TLKEGKKICWPALGLTFAGLVLSIILSLVLPKNIYEHMTTAAGLMLLYTWLFILFSSKKLTDPEGMGKTQIYLAMVLIAA
AVSGTLFEKSSRPGFFVSIGFLVIIAIVTMIYQKKQGHKDRPASP

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily

Homologues:

Organism=Escherichia coli, GI87081708, Length=463, Percent_Identity=24.622030237581, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1786302, Length=391, Percent_Identity=27.8772378516624, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786789, Length=365, Percent_Identity=27.3972602739726, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87081915, Length=382, Percent_Identity=28.2722513089005, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1786602, Length=387, Percent_Identity=26.3565891472868, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790653, Length=463, Percent_Identity=25.0539956803456, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI48994972, Length=463, Percent_Identity=23.7580993520518, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789017, Length=408, Percent_Identity=25.4901960784314, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788480, Length=398, Percent_Identity=25.8793969849246, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324061, Length=382, Percent_Identity=26.1780104712042, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320772, Length=393, Percent_Identity=23.9185750636132, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320251, Length=397, Percent_Identity=23.6775818639798, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324553, Length=383, Percent_Identity=25.3263707571802, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6322967, Length=475, Percent_Identity=24.6315789473684, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319542, Length=399, Percent_Identity=22.0551378446115, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324990, Length=406, Percent_Identity=22.4137931034483, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320717, Length=396, Percent_Identity=21.7171717171717, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324924, Length=351, Percent_Identity=23.6467236467236, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319824, Length=396, Percent_Identity=22.7272727272727, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321053, Length=376, Percent_Identity=22.6063829787234, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324059, Length=291, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321629, Length=388, Percent_Identity=22.9381443298969, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322892, Length=380, Percent_Identity=22.6315789473684, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319543, Length=401, Percent_Identity=21.6957605985037, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324981, Length=464, Percent_Identity=22.6293103448276, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666159, Length=331, Percent_Identity=22.9607250755287, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221512776, Length=331, Percent_Identity=22.9607250755287, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCGH_BACSU (P94383)

Other databases:

- EMBL:   D50453
- EMBL:   AL009126
- PIR:   C69758
- RefSeq:   NP_388193.2
- ProteinModelPortal:   P94383
- EnsemblBacteria:   EBBACT00000002686
- GeneID:   938347
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU03110
- NMPDR:   fig|224308.1.peg.312
- GenoList:   BSU03110
- GeneTree:   EBGT00070000031736
- HOGENOM:   HBG338291
- ProtClustDB:   CLSK873245
- BioCyc:   BSUB:BSU03110-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 48504; Mature: 48373

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xafb73f4)-; HASH(0x40aad610)-; HASH(0xbff5e84)-; HASH(0xcc96558)-; HASH(0xc8e3000)-; HASH(0xb38ea50)-; HASH(0xcc0e130)-; HASH(0xb028b20)-; HASH(0xcc9f7a0)-; HASH(0xc408154)-; HASH(0xbaebc54)-; HASH(0xcc98ca8)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTKKDQPKGNLAWWQLSLIGVGCTIGTGFFLGSSIAIVKSGFSVLLSFLIAGIGTYFV
CCCCCCCCCCCCEEEEEEEEEEECHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHH
FEQLAKLSAKQPEKGSFCAYARKAFGKWAGFSNGWVYWTSEMLITGSQLTAISLFTKHWF
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEECCHHHHHHHHHHHCC
PQVPLWVFASIYAVLGLLIIFTGLSVFEKTENVLAVIKTAAIFMFIVIAILALCGILSGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NHGIHVPNKTSEFFPYGAMGLWTGLIYAFYAFGGIEVMGLMAVHLKKPEEASKSGKLMLA
CCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHH
TLAIIYIISIGLALLLVPLHTFTEQDSPFITSLKGYNLEIILDIFNGIFIIAGFSTLVAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHHHH
LFAVTTLLCTMADDGDAPKCFTLKEGKKICWPALGLTFAGLVLSIILSLVLPKNIYEHMT
HHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAAGLMLLYTWLFILFSSKKLTDPEGMGKTQIYLAMVLIAAAVSGTLFEKSSRPGFFVSI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHH
GFLVIIAIVTMIYQKKQGHKDRPASP
HHHHHHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure 
SQTKKDQPKGNLAWWQLSLIGVGCTIGTGFFLGSSIAIVKSGFSVLLSFLIAGIGTYFV
CCCCCCCCCCCEEEEEEEEEEECHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHH
FEQLAKLSAKQPEKGSFCAYARKAFGKWAGFSNGWVYWTSEMLITGSQLTAISLFTKHWF
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEECCHHHHHHHHHHHCC
PQVPLWVFASIYAVLGLLIIFTGLSVFEKTENVLAVIKTAAIFMFIVIAILALCGILSGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NHGIHVPNKTSEFFPYGAMGLWTGLIYAFYAFGGIEVMGLMAVHLKKPEEASKSGKLMLA
CCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHH
TLAIIYIISIGLALLLVPLHTFTEQDSPFITSLKGYNLEIILDIFNGIFIIAGFSTLVAS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEHHHHHHHHHHHHHHHHHHHH
LFAVTTLLCTMADDGDAPKCFTLKEGKKICWPALGLTFAGLVLSIILSLVLPKNIYEHMT
HHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAAGLMLLYTWLFILFSSKKLTDPEGMGKTQIYLAMVLIAAAVSGTLFEKSSRPGFFVSI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHH
GFLVIIAIVTMIYQKKQGHKDRPASP
HHHHHHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377