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The map label for this gene is mtnN [H]

Identifier: 239618489

GI number: 239618489

Start: 2262259

End: 2262924

Strand: Direct

Name: mtnN [H]

Synonym: Kole_2130

Alternate gene names: 239618489

Gene position: 2262259-2262924 (Clockwise)

Preceding gene: 239618488

Following gene: 239618490

Centisome position: 98.27

GC content: 46.4

Gene sequence:

>666_bases
ATGATTTTAGTGATGAGCGTTTTTAATCCTGAGGTCAAACCACTGCTTGAGGTAATGTTGAAAATCGAAGAAGGTGAGCT
CCTTGGAAGGTCTTACACCAGAGGTCTCATCGGAAAAAATGAGGTAGTTGTGGCGAGCGGGTTCGTAGGAAAAGTGGAAA
CCGCAGCTCTGGCGCAGAAGTTCATCGATGAATTTTCACCAAGGTTGATCGTGATGACATCCGGTGCGGGCGCGATAGAC
AGTTCCATCGAACCGGGAACGGTTGTAATAGGGAGTGAATTTCTTGAGTATGACCTTTATTTGCCACTGCGTTCCGGACA
TATAAGCGTTCCCACAACTGCTTCGGTTGCCCTGGATCATATAAAACAGTTGATGCCCGATGCAACCTATGGAAGGATCA
TCACGGGGGATCAAATTCTGGCGGATACTAAAAAGCGCGATGAGTTGTTCAAACAGTATCACGCATGTTGCCTCGATATG
GATTCAGCGGCTCTCGCGCGTGTTGCCAAAATGAACAGAGTACCCTTTCTGGTTATAAAGGTTATTCTGGACAAGTGCGA
TGAGAACAGTGAGAATGACTTCGGTATCAATTTCGAAAGATACGGGCAGAAACCGGCGAAGATTCTTGCTGAATTGCTGA
GGACCCACGTTCTCGAAATTAAATGA

Upstream 100 bases:

>100_bases
GAAGAAGAAGAAGAAGAGAACTAAATTTCAAAAAAAGATAATTGAGGGAGCGTAGCTCCCTCTTTTTTGTGGCGTTGTAT
AATTTAATAGGGGTGTTATT

Downstream 100 bases:

>100_bases
ATTTTCGATTTCGCAGGGAGGGATAAGATGAATTGTATTTTCTGTAAGATAATCGCTGGCGAGATACCAGCTGGCAAAGT
TGCGGAAACGGAAAACTTCC

Product: Adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MILVMSVFNPEVKPLLEVMLKIEEGELLGRSYTRGLIGKNEVVVASGFVGKVETAALAQKFIDEFSPRLIVMTSGAGAID
SSIEPGTVVIGSEFLEYDLYLPLRSGHISVPTTASVALDHIKQLMPDATYGRIITGDQILADTKKRDELFKQYHACCLDM
DSAALARVAKMNRVPFLVIKVILDKCDENSENDFGINFERYGQKPAKILAELLRTHVLEIK

Sequences:

>Translated_221_residues
MILVMSVFNPEVKPLLEVMLKIEEGELLGRSYTRGLIGKNEVVVASGFVGKVETAALAQKFIDEFSPRLIVMTSGAGAID
SSIEPGTVVIGSEFLEYDLYLPLRSGHISVPTTASVALDHIKQLMPDATYGRIITGDQILADTKKRDELFKQYHACCLDM
DSAALARVAKMNRVPFLVIKVILDKCDENSENDFGINFERYGQKPAKILAELLRTHVLEIK
>Mature_221_residues
MILVMSVFNPEVKPLLEVMLKIEEGELLGRSYTRGLIGKNEVVVASGFVGKVETAALAQKFIDEFSPRLIVMTSGAGAID
SSIEPGTVVIGSEFLEYDLYLPLRSGHISVPTTASVALDHIKQLMPDATYGRIITGDQILADTKKRDELFKQYHACCLDM
DSAALARVAKMNRVPFLVIKVILDKCDENSENDFGINFERYGQKPAKILAELLRTHVLEIK

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24430; Mature: 24430

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVMSVFNPEVKPLLEVMLKIEEGELLGRSYTRGLIGKNEVVVASGFVGKVETAALAQK
CEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHH
FIDEFSPRLIVMTSGAGAIDSSIEPGTVVIGSEFLEYDLYLPLRSGHISVPTTASVALDH
HHHHCCCEEEEEECCCCCCCCCCCCCEEEECCHHEEEEEEEEEECCEECCCCHHHHHHHH
IKQLMPDATYGRIITGDQILADTKKRDELFKQYHACCLDMDSAALARVAKMNRVPFLVIK
HHHHCCCCCCCEEEECCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
VILDKCDENSENDFGINFERYGQKPAKILAELLRTHVLEIK
HHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILVMSVFNPEVKPLLEVMLKIEEGELLGRSYTRGLIGKNEVVVASGFVGKVETAALAQK
CEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHH
FIDEFSPRLIVMTSGAGAIDSSIEPGTVVIGSEFLEYDLYLPLRSGHISVPTTASVALDH
HHHHCCCEEEEEECCCCCCCCCCCCCEEEECCHHEEEEEEEEEECCEECCCCHHHHHHHH
IKQLMPDATYGRIITGDQILADTKKRDELFKQYHACCLDMDSAALARVAKMNRVPFLVIK
HHHHCCCCCCCEEEECCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
VILDKCDENSENDFGINFERYGQKPAKILAELLRTHVLEIK
HHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]