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The map label for this gene is yqhT [H]

Identifier: 239618477

GI number: 239618477

Start: 2250022

End: 2251116

Strand: Reverse

Name: yqhT [H]

Synonym: Kole_2118

Alternate gene names: 239618477

Gene position: 2251116-2250022 (Counterclockwise)

Preceding gene: 239618478

Following gene: 239618476

Centisome position: 97.78

GC content: 40.0

Gene sequence:

>1095_bases
ATGATGGCGGGAGCAAACAATCTGGCAAAGTTGAGAGAAAAAATGGTAAAAGATGATGTAGATGGAGTTATACTTCTTAA
CTTTGAAGATAGAAATCGTGCCACAACGTGGTACGTTTCAGGTTTTTCGGGTTCTTTTGCTGTACTTCTTATAAGTCAAA
AGAAAGAGTATATTCTAACCGATTCACGTTATTACACACAGGCTGCTATGCAAACATCTTTTGAGCTTATTCCGTTGAAA
AACGGCATGGAGACAGTGGAAGAAACTATAATCAAATTTGTGGAAGAGGAAAACATCAAGCGACTCGGTATCGAAGAGGA
GAGAATAACTCTTGCACATTATAAGGATCTTTTTTCCAGGCTTGAAAATGTGGAGATCCTTTCGATAGACGAAACTATTA
AGGGACTTCGTTCGGTAAAATCCCCTGAAGAAATTGAAAAAATAAAAGTAGCCATAGACGTAGCTGAGAAAGCCCTTCTG
GAAACTCTCAATATTATAAAACCAGGAATAACTGAACAGAAAATCGCGGCCGTTCTTGAATATGAGATGAGAAAGCGCGG
CGGTATCCCGGCATTCGAAACTATAGTAGCTTCAGGTTATCGTAGTGCGATAGTTCACGGTAGATCCTCAGAAAAAAAAG
TCAAAGAAGGAGAGTTTATTCTTATCGATTATGGAGCCATGGTGAATGGTTATTGTTCCGATATCACGAGGACTTTCTGT
CTTGGAACGCCTTCAGATGAGATGGTAAAGGTGTATGAAATTGTTTATAATACACAAAAAACCTGCCGTGAAGCCGCAAA
AGCAGGAATGGTTGGAAAAGAACTTCATCTGATGGCGGTTGATATGATTACCAATGCAGGTTACGGAGAATATTTTGGAC
ATGGATTGGGGCATGGCCTGGGAATGGAGGTTCACGAAGCTCCAGCAGTGGGTCTTAAAAACGAGAATCCGTTGCCTTCA
GGTGCTGTCGTTACTATAGAGCCTGGCATATATATTCCGGAGAAATTTGGTGTTCGCATAGAGGATGATGTTTTATTAAC
GGATAACGGAGCAGTAATTCTAACAACTCTAGATAGAAAATTGAAAACACTTTAA

Upstream 100 bases:

>100_bases
AAGAAAAAGAAAGGAAAAATGCATAAGAATCAGATGTCCCTATTCTAATATCAGTTATAATATTTTGAAATGCTATAATT
TTCTTTATGGAGGTTCATTT

Downstream 100 bases:

>100_bases
TCTGGAGGTGTGGTTTGTGGTAGAGGTAGGAGATATAAGAAAGGGAATGGCGTTGATCATTGATAATGATATTTATATAG
TGCTTGATGTAAACAAGCAC

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MMAGANNLAKLREKMVKDDVDGVILLNFEDRNRATTWYVSGFSGSFAVLLISQKKEYILTDSRYYTQAAMQTSFELIPLK
NGMETVEETIIKFVEEENIKRLGIEEERITLAHYKDLFSRLENVEILSIDETIKGLRSVKSPEEIEKIKVAIDVAEKALL
ETLNIIKPGITEQKIAAVLEYEMRKRGGIPAFETIVASGYRSAIVHGRSSEKKVKEGEFILIDYGAMVNGYCSDITRTFC
LGTPSDEMVKVYEIVYNTQKTCREAAKAGMVGKELHLMAVDMITNAGYGEYFGHGLGHGLGMEVHEAPAVGLKNENPLPS
GAVVTIEPGIYIPEKFGVRIEDDVLLTDNGAVILTTLDRKLKTL

Sequences:

>Translated_364_residues
MMAGANNLAKLREKMVKDDVDGVILLNFEDRNRATTWYVSGFSGSFAVLLISQKKEYILTDSRYYTQAAMQTSFELIPLK
NGMETVEETIIKFVEEENIKRLGIEEERITLAHYKDLFSRLENVEILSIDETIKGLRSVKSPEEIEKIKVAIDVAEKALL
ETLNIIKPGITEQKIAAVLEYEMRKRGGIPAFETIVASGYRSAIVHGRSSEKKVKEGEFILIDYGAMVNGYCSDITRTFC
LGTPSDEMVKVYEIVYNTQKTCREAAKAGMVGKELHLMAVDMITNAGYGEYFGHGLGHGLGMEVHEAPAVGLKNENPLPS
GAVVTIEPGIYIPEKFGVRIEDDVLLTDNGAVILTTLDRKLKTL
>Mature_364_residues
MMAGANNLAKLREKMVKDDVDGVILLNFEDRNRATTWYVSGFSGSFAVLLISQKKEYILTDSRYYTQAAMQTSFELIPLK
NGMETVEETIIKFVEEENIKRLGIEEERITLAHYKDLFSRLENVEILSIDETIKGLRSVKSPEEIEKIKVAIDVAEKALL
ETLNIIKPGITEQKIAAVLEYEMRKRGGIPAFETIVASGYRSAIVHGRSSEKKVKEGEFILIDYGAMVNGYCSDITRTFC
LGTPSDEMVKVYEIVYNTQKTCREAAKAGMVGKELHLMAVDMITNAGYGEYFGHGLGHGLGMEVHEAPAVGLKNENPLPS
GAVVTIEPGIYIPEKFGVRIEDDVLLTDNGAVILTTLDRKLKTL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=260, Percent_Identity=34.6153846153846, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI149589008, Length=293, Percent_Identity=26.6211604095563, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI260593665, Length=291, Percent_Identity=26.8041237113402, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI93141226, Length=166, Percent_Identity=34.3373493975904, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI260593663, Length=263, Percent_Identity=27.7566539923954, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI264681563, Length=314, Percent_Identity=28.6624203821656, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI164420681, Length=258, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1788728, Length=360, Percent_Identity=35.2777777777778, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789275, Length=250, Percent_Identity=30.4, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790282, Length=302, Percent_Identity=25.4966887417219, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786364, Length=250, Percent_Identity=24, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71989583, Length=257, Percent_Identity=28.0155642023346, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=25.8503401360544, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17509539, Length=165, Percent_Identity=32.7272727272727, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320922, Length=260, Percent_Identity=28.8461538461538, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321118, Length=288, Percent_Identity=28.4722222222222, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322999, Length=237, Percent_Identity=28.6919831223629, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920384, Length=296, Percent_Identity=28.0405405405405, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357079, Length=293, Percent_Identity=27.9863481228669, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40485; Mature: 40485

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAGANNLAKLREKMVKDDVDGVILLNFEDRNRATTWYVSGFSGSFAVLLISQKKEYILT
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCEEEE
DSRYYTQAAMQTSFELIPLKNGMETVEETIIKFVEEENIKRLGIEEERITLAHYKDLFSR
CCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
LENVEILSIDETIKGLRSVKSPEEIEKIKVAIDVAEKALLETLNIIKPGITEQKIAAVLE
HCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
YEMRKRGGIPAFETIVASGYRSAIVHGRSSEKKVKEGEFILIDYGAMVNGYCSDITRTFC
HHHHHHCCCCHHHHHHHCCCHHHEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHC
LGTPSDEMVKVYEIVYNTQKTCREAAKAGMVGKELHLMAVDMITNAGYGEYFGHGLGHGL
CCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHEEEEEHHHCCCCHHHHHCCCCCCC
GMEVHEAPAVGLKNENPLPSGAVVTIEPGIYIPEKFGVRIEDDVLLTDNGAVILTTLDRK
CCEECCCCCCCCCCCCCCCCCCEEEECCCEECCHHCCCEEECCEEEECCCEEEEEECCHH
LKTL
HHCC
>Mature Secondary Structure
MMAGANNLAKLREKMVKDDVDGVILLNFEDRNRATTWYVSGFSGSFAVLLISQKKEYILT
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCEEEE
DSRYYTQAAMQTSFELIPLKNGMETVEETIIKFVEEENIKRLGIEEERITLAHYKDLFSR
CCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHH
LENVEILSIDETIKGLRSVKSPEEIEKIKVAIDVAEKALLETLNIIKPGITEQKIAAVLE
HCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
YEMRKRGGIPAFETIVASGYRSAIVHGRSSEKKVKEGEFILIDYGAMVNGYCSDITRTFC
HHHHHHCCCCHHHHHHHCCCHHHEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHC
LGTPSDEMVKVYEIVYNTQKTCREAAKAGMVGKELHLMAVDMITNAGYGEYFGHGLGHGL
CCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHEEEEEHHHCCCCHHHHHCCCCCCC
GMEVHEAPAVGLKNENPLPSGAVVTIEPGIYIPEKFGVRIEDDVLLTDNGAVILTTLDRK
CCEECCCCCCCCCCCCCCCCCCEEEECCCEECCHHCCCEEECCEEEECCCEEEEEECCHH
LKTL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]