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The map label for this gene is ytpA [H]

Identifier: 239618459

GI number: 239618459

Start: 2229824

End: 2230615

Strand: Direct

Name: ytpA [H]

Synonym: Kole_2100

Alternate gene names: 239618459

Gene position: 2229824-2230615 (Clockwise)

Preceding gene: 239618456

Following gene: 239618464

Centisome position: 96.86

GC content: 39.02

Gene sequence:

>792_bases
ATGTTCATTAGAAAATGGTCTACAAATAATAAACCCGTGGGAAGTATCATTATCGTTCATGGATTAGAAGAACATTCGGG
GCGTTATGATCCTTTTGCCCGGTTCTTGACTTCAAAAGGGTTTACTGTTTACTCTTCAGATCTTCCAGGCCACGGAGTAA
GTTCCTCACCTTATGGTCATATAGATTCTTTTAATGAATTCTTTGAGACTGTCGAAACCCTTATGAACATTGCTAACATA
GAATTTCCGGATTTACCTCTTTACCTTTTTGGACACAGCATGGGCGCTCTGGTGTCTATAAGAGTTGCACAGGAAAGAAC
GGAAGATTTTAAGGCCTGTGTGTTCAGCGCACCTCCATTACATTCTCTTAAAAAGCAGGCTGGTGGGCTTGTGCCTTTAT
TGATCGTTCTTAATATGGTTGCTCCGTTTGTAAGATTCAGTAATAGAATCGATCCCAACAAACTCTCAACAAACCCTGAG
GCGGTTAAAAGATATATTAATGATCCTTTCGTTCACGACAAAATATCTGCAAGGCTCTTCAACAATATGGATAAGAACAT
ATCAATAGCATGGCAGAAAACGGATAATCTGCCAGATTCGGTTATGTTCGTTTACGGCACTGATGATACCGTGATTTCAG
TTGATGCCATAAAGGAATTCTTTGAAAAAGTCTCTGCTAAAAACAAGCGGATTGTTGAAATTGAAGGAGGAAAACACGAA
ATCTTTGAAGATCTTGAACGCAAAGAGAGATTTTTCAATGAAATAGCCAGCTATTTCTTAGACAACCTGTGA

Upstream 100 bases:

>100_bases
TGAAAATATTATCATAAGAATCGGGGCTTGTAAATACCTGTTTTTTGATTCTAAGCGATAGAGAGTATAATATTTTTGTT
AAAAACGGGGAGGGATAGCG

Downstream 100 bases:

>100_bases
ATCAAGCTTGCTTACCCATTTCCTTGCAATCCTTTCGTCACGCCGTATTGCGTGTACGAGTTCATCGATGGAAGCAAACT
TGAGCTCGGGGCGCAAAAAC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Bacilysocin biosynthesis protein ytpA [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MFIRKWSTNNKPVGSIIIVHGLEEHSGRYDPFARFLTSKGFTVYSSDLPGHGVSSSPYGHIDSFNEFFETVETLMNIANI
EFPDLPLYLFGHSMGALVSIRVAQERTEDFKACVFSAPPLHSLKKQAGGLVPLLIVLNMVAPFVRFSNRIDPNKLSTNPE
AVKRYINDPFVHDKISARLFNNMDKNISIAWQKTDNLPDSVMFVYGTDDTVISVDAIKEFFEKVSAKNKRIVEIEGGKHE
IFEDLERKERFFNEIASYFLDNL

Sequences:

>Translated_263_residues
MFIRKWSTNNKPVGSIIIVHGLEEHSGRYDPFARFLTSKGFTVYSSDLPGHGVSSSPYGHIDSFNEFFETVETLMNIANI
EFPDLPLYLFGHSMGALVSIRVAQERTEDFKACVFSAPPLHSLKKQAGGLVPLLIVLNMVAPFVRFSNRIDPNKLSTNPE
AVKRYINDPFVHDKISARLFNNMDKNISIAWQKTDNLPDSVMFVYGTDDTVISVDAIKEFFEKVSAKNKRIVEIEGGKHE
IFEDLERKERFFNEIASYFLDNL
>Mature_263_residues
MFIRKWSTNNKPVGSIIIVHGLEEHSGRYDPFARFLTSKGFTVYSSDLPGHGVSSSPYGHIDSFNEFFETVETLMNIANI
EFPDLPLYLFGHSMGALVSIRVAQERTEDFKACVFSAPPLHSLKKQAGGLVPLLIVLNMVAPFVRFSNRIDPNKLSTNPE
AVKRYINDPFVHDKISARLFNNMDKNISIAWQKTDNLPDSVMFVYGTDDTVISVDAIKEFFEKVSAKNKRIVEIEGGKHE
IFEDLERKERFFNEIASYFLDNL

Specific function: Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis react

COG id: COG2267

COG function: function code I; Lysophospholipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI51242953, Length=258, Percent_Identity=27.906976744186, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI6005786, Length=258, Percent_Identity=27.906976744186, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR022742 [H]

Pfam domain/function: PF12146 Hydrolase_4 [H]

EC number: NA

Molecular weight: Translated: 29890; Mature: 29890

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIRKWSTNNKPVGSIIIVHGLEEHSGRYDPFARFLTSKGFTVYSSDLPGHGVSSSPYGH
CEEECCCCCCCCCCEEEEEECCHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
IDSFNEFFETVETLMNIANIEFPDLPLYLFGHSMGALVSIRVAQERTEDFKACVFSAPPL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHEEEHHHHHHHHHHHHHHCCCCCH
HSLKKQAGGLVPLLIVLNMVAPFVRFSNRIDPNKLSTNPEAVKRYINDPFVHDKISARLF
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
NNMDKNISIAWQKTDNLPDSVMFVYGTDDTVISVDAIKEFFEKVSAKNKRIVEIEGGKHE
HCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEEECCHHH
IFEDLERKERFFNEIASYFLDNL
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFIRKWSTNNKPVGSIIIVHGLEEHSGRYDPFARFLTSKGFTVYSSDLPGHGVSSSPYGH
CEEECCCCCCCCCCEEEEEECCHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
IDSFNEFFETVETLMNIANIEFPDLPLYLFGHSMGALVSIRVAQERTEDFKACVFSAPPL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHEEEHHHHHHHHHHHHHHCCCCCH
HSLKKQAGGLVPLLIVLNMVAPFVRFSNRIDPNKLSTNPEAVKRYINDPFVHDKISARLF
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
NNMDKNISIAWQKTDNLPDSVMFVYGTDDTVISVDAIKEFFEKVSAKNKRIVEIEGGKHE
HCCCCCEEEEEEECCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEEECCHHH
IFEDLERKERFFNEIASYFLDNL
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]