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The map label for this gene is cloSI [H]

Identifier: 239618451

GI number: 239618451

Start: 2223289

End: 2224998

Strand: Reverse

Name: cloSI [H]

Synonym: Kole_2092

Alternate gene names: 239618451

Gene position: 2224998-2223289 (Counterclockwise)

Preceding gene: 239618452

Following gene: 239618450

Centisome position: 96.65

GC content: 39.65

Gene sequence:

>1710_bases
ATGGCAAAAAAGAGATTTAATCGGTTGCTGATATTCGCTGTGATATCGTTGCTTTTCGCTCTCAGCTTGTCAGGTTGTTT
TAAACCAAAATATGAAGTCGTAACTTCTATATCACCTTTGGACCTTGATGTTACCATAGAAGGTGCAGGTTTTTACAGCA
AAGATACTATGGTAAGTTTTACTGCTCCAAATGTTGAAGGTTACAACTTCGACCATTGGGAAGTAAATGGGGTAAATGTT
GGTAATGCTAACCCGCTCGTAATTATCATTGATTCCCCTAAAAATATTGTGGCAGTGTATAGACCGCTGTACACAATAGA
AGCAGACAGCGAGACCCATTACACAGGAAAATGGTCGTATATAACAGTTACCGTAAAAGACTCTTATGGAAACCCTGTTG
AGAATATTGCCGTATCTCTTAGCAGTGATTATTCTGGATCAATAGCGAGATTTTATTCAGTGAGCACAGAAAAGGTGAGT
GTTGATCCGATAGTTTATACAGACCAATATGGGGTTGCAACCTTTGAGGGATATTTTGTAAGCTCTGGAGAATACTCTTG
TACAGCGTATTTGTCAGATGCTCCAAAGATTGATAGAGTATTTCAGGTGACTGTAAATCCCATTGATTGGCTGTTTTTAG
TATATATGGGAGCGGACAACAATCTGGAATCTGCAGCTTACGTGGATTTGGGGGAAATGGAAACACTGAACAATAATGTT
GCCGTGGTAGGTATCTCTGATGTATCGGATTCTTTATACGAATACTTCACAGACGATTTTTATTTCTGGTTGGATGAAAC
AGGAGAAATGTATACTGAAGACATCGGTAGGGAAGTGGATTCAGGTTCTCCTGCAGAATTACAACAATTCTTAGAAGACT
TCTATTCCATAGAGGCGAATCATAAGGCACTCATATTGTGGAATCATGGTGGAGCCTGGTTAGATGAAGACGCAACGCGT
ACCAGAGGCATAATTTACGATGATACTAGTGATACATTCCTTAAAATTAAGGAAGTTCAAGATGTTTTGGAGACGGTTCT
TAATGGGGAAAAACTCGACATTCTAGGCATGGATGCCTGTTTGATGAGCACCGTAGAGGTAGCTTATCAATTAAGAAACA
CATCAGATTATTTTGTAGCTTCCGCCTTTTCTGAACCCGGAGACGGTTGGGATTATGATTTCTTAGATGATATCGGACCT
TTGGATGATGCTTATGATGTGGCTAAAAATATAGTGGACAGGTACTTCGAATCACTTCCCTATACTGTGGAATTGAGCCT
TTCAGTATGGAAAATGGGATGTATGGATGAGCTATATTCGGAAATTGATAATTTTGCGCGTGAACTGGATCAGGAATTAA
CTGCGGATTTAAAATCAAGGATATTGAATACATATTACCCGGCAATAACCCAGTATTATGTGGATTATTATCATGGTGCC
GTGTTATGTGAAATTGGCGATTTTATTGGTTACATTTACAATGATGAAGGTGTATCTCAAGATGTTAAAGACAGTGCCTA
CTCCGCGTGGGTAGCCCTAGATGCTGCCGTCCCGTATTCGCTAATACGCGGTGGAGGTGCTAATTCAAAAGGCGTTAGCA
TTTTCCTTCCGGAAACTTACGATGCTTATAATGCTTATTATTCCGCTTTTAACTTACTCGATTTCTGGTGGAATTACTGG
GAGATCCTTGCGAGTCATATACTAAACTAA

Upstream 100 bases:

>100_bases
CTTAGATTCAGTTTCCAAGAAATGATATAATTAAAATCTTTAATATCGTAACCCGTGAATGATATTTAAATCTAATTAAC
TAATTTAAAGGAGGAATAAA

Downstream 100 bases:

>100_bases
TTAACTACAATTCCACCGGTTACCGGCGGATTATTGAATATCTGAAATTAATCGTACCTTTGTAGGAAGCAAATGATAAA
TGATTATCGAGCAGGGGGGA

Product: peptidase C11 clostripain

Products: NA

Alternate protein names: Clostridiopeptidase B [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MAKKRFNRLLIFAVISLLFALSLSGCFKPKYEVVTSISPLDLDVTIEGAGFYSKDTMVSFTAPNVEGYNFDHWEVNGVNV
GNANPLVIIIDSPKNIVAVYRPLYTIEADSETHYTGKWSYITVTVKDSYGNPVENIAVSLSSDYSGSIARFYSVSTEKVS
VDPIVYTDQYGVATFEGYFVSSGEYSCTAYLSDAPKIDRVFQVTVNPIDWLFLVYMGADNNLESAAYVDLGEMETLNNNV
AVVGISDVSDSLYEYFTDDFYFWLDETGEMYTEDIGREVDSGSPAELQQFLEDFYSIEANHKALILWNHGGAWLDEDATR
TRGIIYDDTSDTFLKIKEVQDVLETVLNGEKLDILGMDACLMSTVEVAYQLRNTSDYFVASAFSEPGDGWDYDFLDDIGP
LDDAYDVAKNIVDRYFESLPYTVELSLSVWKMGCMDELYSEIDNFARELDQELTADLKSRILNTYYPAITQYYVDYYHGA
VLCEIGDFIGYIYNDEGVSQDVKDSAYSAWVALDAAVPYSLIRGGGANSKGVSIFLPETYDAYNAYYSAFNLLDFWWNYW
EILASHILN

Sequences:

>Translated_569_residues
MAKKRFNRLLIFAVISLLFALSLSGCFKPKYEVVTSISPLDLDVTIEGAGFYSKDTMVSFTAPNVEGYNFDHWEVNGVNV
GNANPLVIIIDSPKNIVAVYRPLYTIEADSETHYTGKWSYITVTVKDSYGNPVENIAVSLSSDYSGSIARFYSVSTEKVS
VDPIVYTDQYGVATFEGYFVSSGEYSCTAYLSDAPKIDRVFQVTVNPIDWLFLVYMGADNNLESAAYVDLGEMETLNNNV
AVVGISDVSDSLYEYFTDDFYFWLDETGEMYTEDIGREVDSGSPAELQQFLEDFYSIEANHKALILWNHGGAWLDEDATR
TRGIIYDDTSDTFLKIKEVQDVLETVLNGEKLDILGMDACLMSTVEVAYQLRNTSDYFVASAFSEPGDGWDYDFLDDIGP
LDDAYDVAKNIVDRYFESLPYTVELSLSVWKMGCMDELYSEIDNFARELDQELTADLKSRILNTYYPAITQYYVDYYHGA
VLCEIGDFIGYIYNDEGVSQDVKDSAYSAWVALDAAVPYSLIRGGGANSKGVSIFLPETYDAYNAYYSAFNLLDFWWNYW
EILASHILN
>Mature_568_residues
AKKRFNRLLIFAVISLLFALSLSGCFKPKYEVVTSISPLDLDVTIEGAGFYSKDTMVSFTAPNVEGYNFDHWEVNGVNVG
NANPLVIIIDSPKNIVAVYRPLYTIEADSETHYTGKWSYITVTVKDSYGNPVENIAVSLSSDYSGSIARFYSVSTEKVSV
DPIVYTDQYGVATFEGYFVSSGEYSCTAYLSDAPKIDRVFQVTVNPIDWLFLVYMGADNNLESAAYVDLGEMETLNNNVA
VVGISDVSDSLYEYFTDDFYFWLDETGEMYTEDIGREVDSGSPAELQQFLEDFYSIEANHKALILWNHGGAWLDEDATRT
RGIIYDDTSDTFLKIKEVQDVLETVLNGEKLDILGMDACLMSTVEVAYQLRNTSDYFVASAFSEPGDGWDYDFLDDIGPL
DDAYDVAKNIVDRYFESLPYTVELSLSVWKMGCMDELYSEIDNFARELDQELTADLKSRILNTYYPAITQYYVDYYHGAV
LCEIGDFIGYIYNDEGVSQDVKDSAYSAWVALDAAVPYSLIRGGGANSKGVSIFLPETYDAYNAYYSAFNLLDFWWNYWE
ILASHILN

Specific function: Cysteine endopeptidase with strict specificity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C11 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014173
- InterPro:   IPR005077 [H]

Pfam domain/function: PF03415 Peptidase_C11 [H]

EC number: =3.4.22.8 [H]

Molecular weight: Translated: 64103; Mature: 63971

Theoretical pI: Translated: 3.85; Mature: 3.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKRFNRLLIFAVISLLFALSLSGCFKPKYEVVTSISPLDLDVTIEGAGFYSKDTMVSF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCEECCCCEEEE
TAPNVEGYNFDHWEVNGVNVGNANPLVIIIDSPKNIVAVYRPLYTIEADSETHYTGKWSY
ECCCCCCCCCCCEEECEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCEEECEEEE
ITVTVKDSYGNPVENIAVSLSSDYSGSIARFYSVSTEKVSVDPIVYTDQYGVATFEGYFV
EEEEEECCCCCCHHHEEEEECCCCCCCEEEEEECCCCEEEECEEEEECCCCCEEEEEEEE
SSGEYSCTAYLSDAPKIDRVFQVTVNPIDWLFLVYMGADNNLESAAYVDLGEMETLNNNV
ECCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEEEEECCCHHCCCCCE
AVVGISDVSDSLYEYFTDDFYFWLDETGEMYTEDIGREVDSGSPAELQQFLEDFYSIEAN
EEEEECHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
HKALILWNHGGAWLDEDATRTRGIIYDDTSDTFLKIKEVQDVLETVLNGEKLDILGMDAC
CEEEEEECCCCCCCCCCCHHHCCEEEECCCCCEEEHHHHHHHHHHHHCCCEEEEEECHHH
LMSTVEVAYQLRNTSDYFVASAFSEPGDGWDYDFLDDIGPLDDAYDVAKNIVDRYFESLP
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCC
YTVELSLSVWKMGCMDELYSEIDNFARELDQELTADLKSRILNTYYPAITQYYVDYYHGA
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VLCEIGDFIGYIYNDEGVSQDVKDSAYSAWVALDAAVPYSLIRGGGANSKGVSIFLPETY
EEEEHHHHHEEEECCCCCCCHHHHHHHHEEEEEECCCCHHHHCCCCCCCCCEEEEECCCC
DAYNAYYSAFNLLDFWWNYWEILASHILN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKRFNRLLIFAVISLLFALSLSGCFKPKYEVVTSISPLDLDVTIEGAGFYSKDTMVSF
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEEEEECCCEECCCCEEEE
TAPNVEGYNFDHWEVNGVNVGNANPLVIIIDSPKNIVAVYRPLYTIEADSETHYTGKWSY
ECCCCCCCCCCCEEECEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCEEECEEEE
ITVTVKDSYGNPVENIAVSLSSDYSGSIARFYSVSTEKVSVDPIVYTDQYGVATFEGYFV
EEEEEECCCCCCHHHEEEEECCCCCCCEEEEEECCCCEEEECEEEEECCCCCEEEEEEEE
SSGEYSCTAYLSDAPKIDRVFQVTVNPIDWLFLVYMGADNNLESAAYVDLGEMETLNNNV
ECCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCEEEEECCCHHCCCCCE
AVVGISDVSDSLYEYFTDDFYFWLDETGEMYTEDIGREVDSGSPAELQQFLEDFYSIEAN
EEEEECHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
HKALILWNHGGAWLDEDATRTRGIIYDDTSDTFLKIKEVQDVLETVLNGEKLDILGMDAC
CEEEEEECCCCCCCCCCCHHHCCEEEECCCCCEEEHHHHHHHHHHHHCCCEEEEEECHHH
LMSTVEVAYQLRNTSDYFVASAFSEPGDGWDYDFLDDIGPLDDAYDVAKNIVDRYFESLP
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCC
YTVELSLSVWKMGCMDELYSEIDNFARELDQELTADLKSRILNTYYPAITQYYVDYYHGA
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VLCEIGDFIGYIYNDEGVSQDVKDSAYSAWVALDAAVPYSLIRGGGANSKGVSIFLPETY
EEEEHHHHHEEEECCCCCCCHHHHHHHHEEEEEECCCCHHHHCCCCCCCCCEEEEECCCC
DAYNAYYSAFNLLDFWWNYWEILASHILN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8341259; 6391922; 6337850 [H]