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The map label for this gene is mrpE [H]

Identifier: 239618423

GI number: 239618423

Start: 2190639

End: 2191130

Strand: Reverse

Name: mrpE [H]

Synonym: Kole_2063

Alternate gene names: 239618423

Gene position: 2191130-2190639 (Counterclockwise)

Preceding gene: 239618426

Following gene: 239618422

Centisome position: 95.18

GC content: 43.29

Gene sequence:

>492_bases
ATGGCCAGAAATTATATCTCCGTAATTTTAGTTACTTTTCTAATCTGGCTTGGACTCACAGCAAGCTTTGCACCAGGGGA
AATAATAACGGGATTGGCAGTTTCCATGATAGTCGCTCAGCTCTTGGGCAGGTACGCACGATTTAACCTCCGAGTCGATC
TCCCCATCCGCATTGTGAAATACCTGTTCATGTATCTTCCGCTGTTCATAGTCGAGATGATAAAAGCAAATCTTGACGTT
GCACGACGCGTTTTGAATCCAAAACTTCCCATTAACCCGGCTATCGTGAAAATCCCCACGAACCTGAAAGGAGATTTCTC
TAAGCTAACTCTCGCCAATTCTATAACGCTGACTCCAGGCACATTGACTGTAGATATGGATGAAGAAAATCTCTACGTTC
ATTGGATCGATGCTAAAAGTCTCGATCCCAATGAAGCAAAAAAGATTATCTCTGAAACCTTTGAGCGCAAGATTGGGGGG
ATATTCGAATGA

Upstream 100 bases:

>100_bases
TTGCATCTCTAGCAATCAGGTTACTACCGTTACCGGGTTATGGTATCATATTACTGTAAAAAACGTGCATAATTTCACAA
ATTCACAAGGAGGTACCGAG

Downstream 100 bases:

>100_bases
TTTTGTTTATCTTCCTTGTGCTTGTTGCTTTAGGCTTTATTCTGGCTTTATTTAGAGTTTTTGTTGGTCCAACAGTTCCA
GATAGAATCGTTGCACTCGA

Product: cation antiporter

Products: NA

Alternate protein names: Mrp complex subunit E; Multiple resistance and pH homeostasis protein E [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MARNYISVILVTFLIWLGLTASFAPGEIITGLAVSMIVAQLLGRYARFNLRVDLPIRIVKYLFMYLPLFIVEMIKANLDV
ARRVLNPKLPINPAIVKIPTNLKGDFSKLTLANSITLTPGTLTVDMDEENLYVHWIDAKSLDPNEAKKIISETFERKIGG
IFE

Sequences:

>Translated_163_residues
MARNYISVILVTFLIWLGLTASFAPGEIITGLAVSMIVAQLLGRYARFNLRVDLPIRIVKYLFMYLPLFIVEMIKANLDV
ARRVLNPKLPINPAIVKIPTNLKGDFSKLTLANSITLTPGTLTVDMDEENLYVHWIDAKSLDPNEAKKIISETFERKIGG
IFE
>Mature_162_residues
ARNYISVILVTFLIWLGLTASFAPGEIITGLAVSMIVAQLLGRYARFNLRVDLPIRIVKYLFMYLPLFIVEMIKANLDVA
RRVLNPKLPINPAIVKIPTNLKGDFSKLTLANSITLTPGTLTVDMDEENLYVHWIDAKSLDPNEAKKIISETFERKIGGI
FE

Specific function: Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance [H]

COG id: COG1863

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhE subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002758 [H]

Pfam domain/function: PF01899 MNHE [H]

EC number: NA

Molecular weight: Translated: 18335; Mature: 18204

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNYISVILVTFLIWLGLTASFAPGEIITGLAVSMIVAQLLGRYARFNLRVDLPIRIVK
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHH
YLFMYLPLFIVEMIKANLDVARRVLNPKLPINPAIVKIPTNLKGDFSKLTLANSITLTPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHEEEECEEEECCC
TLTVDMDEENLYVHWIDAKSLDPNEAKKIISETFERKIGGIFE
EEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ARNYISVILVTFLIWLGLTASFAPGEIITGLAVSMIVAQLLGRYARFNLRVDLPIRIVK
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHH
YLFMYLPLFIVEMIKANLDVARRVLNPKLPINPAIVKIPTNLKGDFSKLTLANSITLTPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHEEEECEEEECCC
TLTVDMDEENLYVHWIDAKSLDPNEAKKIISETFERKIGGIFE
EEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]