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The map label for this gene is clpB [H]

Identifier: 239618401

GI number: 239618401

Start: 2167880

End: 2170366

Strand: Direct

Name: clpB [H]

Synonym: Kole_2041

Alternate gene names: 239618401

Gene position: 2167880-2170366 (Clockwise)

Preceding gene: 239618400

Following gene: 239618402

Centisome position: 94.17

GC content: 44.91

Gene sequence:

>2487_bases
ATGTATTTCGATAAATTTTCTGAGGGAGCCGCACAGGTATTTGTAGCTGCCCAGGATGAAGCAAGGAGCCTGGGGCATCC
ATATGTTGGGACGGAACACTTATTGCTCGCTATATTAAAGGTGAACTCTGGAACCACTTCTCAATTACTCAAGGGATACT
CCATAACGTATGAGCGTGTTCTGAGGGAAGTAACATCTATGGTTGGAACGAACATTCGGCAATCAGTGGTTGGTTCCCCT
CAAATGACTCCACGTGCCAGACGCGTCATCGAGCTGGCCAATGACGAGTCAAGAATGCTGGGACAGGACAAAATAGATGT
TGAACATATAATGTTAGGTATAGTTCGCGAAGGTGAAGGAATAGCTGCTCACATCTTGAAACAGATGGGTGTCAATCTTG
GCAAACTGAGAAAACAACTTATAGAAAATATTACGAGTGACTGGGACGAGTCTACAACGGGCGGACGTTCTTTCGGTGCT
CAGCAATCAAGCATGGCTACTTCTTTGAAACAACTGGAAGGATTTGGAACGGATTTGACCGCTCTGGCGCGTGCGGGAAA
ACTCGACCCCATAATCGGACGTGATGTTGAAAAGCAGAGATTAATGGAAGTGCTCTCCAGGAGGAAGAAAAACAACCCCG
TTCTCATAGGAGATCCGGGTGTAGGAAAGACCGCTATCGTGGAAGGACTCGCGCAGATGATTGTCAATGAAGAGGTTCCA
GAGACCTTGAAAAATAAAGCAATTTTTGCTCTTGATGTTGCTTCGTTGATTGCCGGTACAAAATACCGTGGAGAGTTTGA
AAAGCGTTTGAAGAAGCTCATACAGGTTGTAAAGAATAATGGGAACATAATCCTTTTCATTGATGAACTTCACACGATAG
TTGGTGCTGGTTCTGCCGAGGGTGCTGTCGATGCCGCTAATATATTGAAACCAGCTCTGGCAAGCGGCGAGATAAGATGT
ATAGGTTCTACAACTCCTGATGAATACAGAAAATACGTTGAAAAGGACGCTGCCCTGGAAAGACGTTTCCAGAAGATTTA
TGTTTCTGAACCCACGGTCGAGCAGACAATCGGAATTCTGAGAGGCATCAAGCACAAATATGAGGCACATCATAAGGTCT
ACTATACTGATGCCGCGTTGGAAGCTGCTGTTTTATTGTCTCACAGGTATGTCAGTGACCGCTTCCTCCCGGATAAAGCG
ATAGACATTATCGATGAAGCTGGTGCACGTGCCAGACTTAGAAAACTAACTGTACCATCTTATTTGAAAGAACTTCAGAA
AAAGATAGAGAAGCTCAGGCTTGAGCGAGAAGACGCGGTTTCTCGACAGGATTACGAGCATGCAGCAGAACTAAAAGAAG
AAGAAAGGGTTTTGATGAAAACCTATAAGGACGAATACAATAATTGGCGTGAGAAGGTTGACTCAGAAATTGTTCAAATA
AGTGAAGAAGAGGTTGCTGAGATTGTTTCTAGCTGGACCGGTATCCCGCTGAAGAAGTTGGAGCAGTCGGATAGCGAAAG
ACTCCTTTCACTGGAAGAGGCTCTTCACAAACGAATCGTCGGCCAGGATGAAGCAATAACGGCAGTTGCAAAAGCCATAA
GAAGAGCAAGAAGTGGGCTTAAAGATCCCAGACGGCCCATCGGTACCTTCCTGTTCCTTGGACCTACCGGGGTCGGGAAA
ACGGAGTTAGCAAAGGCTCTTGCCGAATACCTTTTTGGCGATGAAAAGGCTCTCGTCAGATTCGATATGTCTGAGTATAT
GGAAAGGTTCTCTGTGTCTCGTTTGATCGGGGCACCACCGGGATACGTTGGATATGATGAAGGTGGAACACTCACCGAAA
GAATAAGGAAGCGTCCTTTTTCCATTATTCTTTTCGATGAAATCGAAAAAGCCCATTTCGACATTTTCAATCTACTCCTC
CAGATCATGGATGATGGCCGTCTTACTGATTCTCAGGGTCGCAGCGTTGACTTCAAAAACACAATAGTCATAATGACCAG
CAACCTTGGTGGTGAGTTTATTAACAAGACGAAGAAAACACTGGGGTTTGTAAGTGCGGCAAATGTTGAGGAAAAAGAGT
ATGAATCGATGAAAAACTCCGTTCTTGAAGAAGTGAAGAAAACCTTCAGGCCTGAGTTTTTGAACAGGCTGGACGAAATC
GTCGTCTTCCATCCGCTGACGAGAGAGCAGATCAAGAAGATTATCGAGATTCTCATTTCGGATACGAGAAAACGGCTTAA
AGAAAAGAAAATGGACCTAGTATTATCTGAAGCAGCTCAGGAGTTCCTTGTTGAGAAAGGGTTTGATCCTGTCTACGGTG
CGCGGCCATTACGTAGAGCAATTCAGAGATACATAGAAGACCCTCTCGCGGAGGAGGTGCTCAGAGGTAGATTTGAGCCT
GGTGACACAATAATGGTTGTAAGGCAGGATGAAAAACTTTCCTTTAAAAAGAGCAAGAAGAAGGTTGAGGTAAAAGCTGG
AACATGA

Upstream 100 bases:

>100_bases
ATGGAACGATGAGTGTAGAAAAGATACACGAACAGGTAGTGAAGGAATTTCTTCTTTGCCTCAAAAAGCTGGGGCACGGT
CTGTAACCGGAGGTGATACG

Downstream 100 bases:

>100_bases
GTAGAAAGAAACGAAGGATTTACGTATGTGATGCCTGTGGTTATGAATCTCCCGCGTGGTTTGGAAGATGCCCGAGTTGC
GGAACCTGGAATAGTGCGAT

Product: ATPase AAA-2 domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 828; Mature: 828

Protein sequence:

>828_residues
MYFDKFSEGAAQVFVAAQDEARSLGHPYVGTEHLLLAILKVNSGTTSQLLKGYSITYERVLREVTSMVGTNIRQSVVGSP
QMTPRARRVIELANDESRMLGQDKIDVEHIMLGIVREGEGIAAHILKQMGVNLGKLRKQLIENITSDWDESTTGGRSFGA
QQSSMATSLKQLEGFGTDLTALARAGKLDPIIGRDVEKQRLMEVLSRRKKNNPVLIGDPGVGKTAIVEGLAQMIVNEEVP
ETLKNKAIFALDVASLIAGTKYRGEFEKRLKKLIQVVKNNGNIILFIDELHTIVGAGSAEGAVDAANILKPALASGEIRC
IGSTTPDEYRKYVEKDAALERRFQKIYVSEPTVEQTIGILRGIKHKYEAHHKVYYTDAALEAAVLLSHRYVSDRFLPDKA
IDIIDEAGARARLRKLTVPSYLKELQKKIEKLRLEREDAVSRQDYEHAAELKEEERVLMKTYKDEYNNWREKVDSEIVQI
SEEEVAEIVSSWTGIPLKKLEQSDSERLLSLEEALHKRIVGQDEAITAVAKAIRRARSGLKDPRRPIGTFLFLGPTGVGK
TELAKALAEYLFGDEKALVRFDMSEYMERFSVSRLIGAPPGYVGYDEGGTLTERIRKRPFSIILFDEIEKAHFDIFNLLL
QIMDDGRLTDSQGRSVDFKNTIVIMTSNLGGEFINKTKKTLGFVSAANVEEKEYESMKNSVLEEVKKTFRPEFLNRLDEI
VVFHPLTREQIKKIIEILISDTRKRLKEKKMDLVLSEAAQEFLVEKGFDPVYGARPLRRAIQRYIEDPLAEEVLRGRFEP
GDTIMVVRQDEKLSFKKSKKKVEVKAGT

Sequences:

>Translated_828_residues
MYFDKFSEGAAQVFVAAQDEARSLGHPYVGTEHLLLAILKVNSGTTSQLLKGYSITYERVLREVTSMVGTNIRQSVVGSP
QMTPRARRVIELANDESRMLGQDKIDVEHIMLGIVREGEGIAAHILKQMGVNLGKLRKQLIENITSDWDESTTGGRSFGA
QQSSMATSLKQLEGFGTDLTALARAGKLDPIIGRDVEKQRLMEVLSRRKKNNPVLIGDPGVGKTAIVEGLAQMIVNEEVP
ETLKNKAIFALDVASLIAGTKYRGEFEKRLKKLIQVVKNNGNIILFIDELHTIVGAGSAEGAVDAANILKPALASGEIRC
IGSTTPDEYRKYVEKDAALERRFQKIYVSEPTVEQTIGILRGIKHKYEAHHKVYYTDAALEAAVLLSHRYVSDRFLPDKA
IDIIDEAGARARLRKLTVPSYLKELQKKIEKLRLEREDAVSRQDYEHAAELKEEERVLMKTYKDEYNNWREKVDSEIVQI
SEEEVAEIVSSWTGIPLKKLEQSDSERLLSLEEALHKRIVGQDEAITAVAKAIRRARSGLKDPRRPIGTFLFLGPTGVGK
TELAKALAEYLFGDEKALVRFDMSEYMERFSVSRLIGAPPGYVGYDEGGTLTERIRKRPFSIILFDEIEKAHFDIFNLLL
QIMDDGRLTDSQGRSVDFKNTIVIMTSNLGGEFINKTKKTLGFVSAANVEEKEYESMKNSVLEEVKKTFRPEFLNRLDEI
VVFHPLTREQIKKIIEILISDTRKRLKEKKMDLVLSEAAQEFLVEKGFDPVYGARPLRRAIQRYIEDPLAEEVLRGRFEP
GDTIMVVRQDEKLSFKKSKKKVEVKAGT
>Mature_828_residues
MYFDKFSEGAAQVFVAAQDEARSLGHPYVGTEHLLLAILKVNSGTTSQLLKGYSITYERVLREVTSMVGTNIRQSVVGSP
QMTPRARRVIELANDESRMLGQDKIDVEHIMLGIVREGEGIAAHILKQMGVNLGKLRKQLIENITSDWDESTTGGRSFGA
QQSSMATSLKQLEGFGTDLTALARAGKLDPIIGRDVEKQRLMEVLSRRKKNNPVLIGDPGVGKTAIVEGLAQMIVNEEVP
ETLKNKAIFALDVASLIAGTKYRGEFEKRLKKLIQVVKNNGNIILFIDELHTIVGAGSAEGAVDAANILKPALASGEIRC
IGSTTPDEYRKYVEKDAALERRFQKIYVSEPTVEQTIGILRGIKHKYEAHHKVYYTDAALEAAVLLSHRYVSDRFLPDKA
IDIIDEAGARARLRKLTVPSYLKELQKKIEKLRLEREDAVSRQDYEHAAELKEEERVLMKTYKDEYNNWREKVDSEIVQI
SEEEVAEIVSSWTGIPLKKLEQSDSERLLSLEEALHKRIVGQDEAITAVAKAIRRARSGLKDPRRPIGTFLFLGPTGVGK
TELAKALAEYLFGDEKALVRFDMSEYMERFSVSRLIGAPPGYVGYDEGGTLTERIRKRPFSIILFDEIEKAHFDIFNLLL
QIMDDGRLTDSQGRSVDFKNTIVIMTSNLGGEFINKTKKTLGFVSAANVEEKEYESMKNSVLEEVKKTFRPEFLNRLDEI
VVFHPLTREQIKKIIEILISDTRKRLKEKKMDLVLSEAAQEFLVEKGFDPVYGARPLRRAIQRYIEDPLAEEVLRGRFEP
GDTIMVVRQDEKLSFKKSKKKVEVKAGT

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=329, Percent_Identity=35.5623100303951, Blast_Score=209, Evalue=1e-53,
Organism=Escherichia coli, GI1787109, Length=806, Percent_Identity=41.5632754342432, Blast_Score=570, Evalue=1e-163,
Organism=Escherichia coli, GI1788943, Length=326, Percent_Identity=55.8282208588957, Blast_Score=403, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320464, Length=706, Percent_Identity=46.600566572238, Blast_Score=627, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6323002, Length=882, Percent_Identity=36.734693877551, Blast_Score=544, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93264; Mature: 93264

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFDKFSEGAAQVFVAAQDEARSLGHPYVGTEHLLLAILKVNSGTTSQLLKGYSITYERV
CCCCCCCCCCCEEEEEECHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHH
LREVTSMVGTNIRQSVVGSPQMTPRARRVIELANDESRMLGQDKIDVEHIMLGIVREGEG
HHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCC
IAAHILKQMGVNLGKLRKQLIENITSDWDESTTGGRSFGAQQSSMATSLKQLEGFGTDLT
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
ALARAGKLDPIIGRDVEKQRLMEVLSRRKKNNPVLIGDPGVGKTAIVEGLAQMIVNEEVP
HHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCHHHH
ETLKNKAIFALDVASLIAGTKYRGEFEKRLKKLIQVVKNNGNIILFIDELHTIVGAGSAE
HHHHCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCC
GAVDAANILKPALASGEIRCIGSTTPDEYRKYVEKDAALERRFQKIYVSEPTVEQTIGIL
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGIKHKYEAHHKVYYTDAALEAAVLLSHRYVSDRFLPDKAIDIIDEAGARARLRKLTVPS
HHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCHHH
YLKELQKKIEKLRLEREDAVSRQDYEHAAELKEEERVLMKTYKDEYNNWREKVDSEIVQI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SEEEVAEIVSSWTGIPLKKLEQSDSERLLSLEEALHKRIVGQDEAITAVAKAIRRARSGL
CHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
KDPRRPIGTFLFLGPTGVGKTELAKALAEYLFGDEKALVRFDMSEYMERFSVSRLIGAPP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCC
GYVGYDEGGTLTERIRKRPFSIILFDEIEKAHFDIFNLLLQIMDDGRLTDSQGRSVDFKN
CCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
TIVIMTSNLGGEFINKTKKTLGFVSAANVEEKEYESMKNSVLEEVKKTFRPEFLNRLDEI
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHE
VVFHPLTREQIKKIIEILISDTRKRLKEKKMDLVLSEAAQEFLVEKGFDPVYGARPLRRA
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IQRYIEDPLAEEVLRGRFEPGDTIMVVRQDEKLSFKKSKKKVEVKAGT
HHHHHHCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MYFDKFSEGAAQVFVAAQDEARSLGHPYVGTEHLLLAILKVNSGTTSQLLKGYSITYERV
CCCCCCCCCCCEEEEEECHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHH
LREVTSMVGTNIRQSVVGSPQMTPRARRVIELANDESRMLGQDKIDVEHIMLGIVREGEG
HHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCC
IAAHILKQMGVNLGKLRKQLIENITSDWDESTTGGRSFGAQQSSMATSLKQLEGFGTDLT
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
ALARAGKLDPIIGRDVEKQRLMEVLSRRKKNNPVLIGDPGVGKTAIVEGLAQMIVNEEVP
HHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCHHHH
ETLKNKAIFALDVASLIAGTKYRGEFEKRLKKLIQVVKNNGNIILFIDELHTIVGAGSAE
HHHHCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCC
GAVDAANILKPALASGEIRCIGSTTPDEYRKYVEKDAALERRFQKIYVSEPTVEQTIGIL
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RGIKHKYEAHHKVYYTDAALEAAVLLSHRYVSDRFLPDKAIDIIDEAGARARLRKLTVPS
HHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCHHH
YLKELQKKIEKLRLEREDAVSRQDYEHAAELKEEERVLMKTYKDEYNNWREKVDSEIVQI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SEEEVAEIVSSWTGIPLKKLEQSDSERLLSLEEALHKRIVGQDEAITAVAKAIRRARSGL
CHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
KDPRRPIGTFLFLGPTGVGKTELAKALAEYLFGDEKALVRFDMSEYMERFSVSRLIGAPP
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCC
GYVGYDEGGTLTERIRKRPFSIILFDEIEKAHFDIFNLLLQIMDDGRLTDSQGRSVDFKN
CCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
TIVIMTSNLGGEFINKTKKTLGFVSAANVEEKEYESMKNSVLEEVKKTFRPEFLNRLDEI
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHE
VVFHPLTREQIKKIIEILISDTRKRLKEKKMDLVLSEAAQEFLVEKGFDPVYGARPLRRA
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IQRYIEDPLAEEVLRGRFEPGDTIMVVRQDEKLSFKKSKKKVEVKAGT
HHHHHHCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]