Click here to switch to the map view.

The map label for this gene is mutL [H]

Identifier: 239618395

GI number: 239618395

Start: 2161448

End: 2162815

Strand: Direct

Name: mutL [H]

Synonym: Kole_2035

Alternate gene names: 239618395

Gene position: 2161448-2162815 (Clockwise)

Preceding gene: 239618394

Following gene: 239618398

Centisome position: 93.89

GC content: 45.69

Gene sequence:

>1368_bases
ATGAAGGTAGATATATTGACAGCAGAAATCGGGAGCACCACAACGGTGCTCTCGGCGTTTATTTCCGACGGCTCTGGAAA
GATGAAGTTTTTGGGTCAGGGCGAGTTTTATACAACGGTCAATGAAGGAGACGTAACAATAGGAATCGAAAAAGCGATTG
ATGTTTTGAAGCACCGGCTTAACGAAAGCAAACTTGATTACGAATTGCTGCTGGCTACGAGCAGTGCTGCTGGCGGTTTG
AAAATGACGGTGCACGGGCTGGTTTATGATATGACCGTTAAGGCTGCAAAGGAAGCTGCTCTTGGTGCTGGGGCAGTTAT
CAAATACGTTACTGCCGGAAAGATGACAGAGCATGATCTTGAAAAAGTTCTGGAGATTGATCCGCGTTTGATCCTACTTG
CTGGAGGAGTCGATTACGGAGAAAGGGAAACTGTTCTGCACAACGCGGAGATGCTCGCAAAACTCCCGCTGAATGTTCCG
ATTATTTATGCCGGCAATATTACAGCCGCTGAGGAAGCCCAAAGGGTTCTTGAAGCATCGGGAAAGGAAGTTTTGGTAAC
AGAAAATGTTTATCCACGAATTGACCAGTTGAACGTTGAACCAACCAGGAAAATTATCAGGGATGTCTTTGCGAAACATA
TAGTAAAAGGTCCTGGAATGGACAAAATCTATTCTATTGTTGGTAGAAATGTTATCCCGACGCCGGCGGCGGTAATGCTC
ACAACCGAATTGCTGGCTGAGGAGTACGAAGATGTCCTTGTGGTAGATATAGGCGGTGCAACAACGGATGTTGATTCCTA
TACCAGTGGAGATCCTGAGATCCAGAAGATTCTTATAGCTCCTGAACCTCTTGCCAAGCGTACGGTTGAAGGGGATCTAG
GGGTTTTTGTTAATGCGAAGAATGTGATTGATTACATAGGAAAAGACGCGTTGATGACAGAATTCAACGATTTTGAAGAG
ATAATCAGGGAGATATCGCCATATCCGAAGAATTCAAGAACGGAAACGTTCATTTCTCGTCTGGCAAAATACTGTTTTGA
AACCTCAATCCGGCGTCATGCGGGAAGGATCAGGCAGTTGTATGGTCCCCTCGGCCGTGTTGAAGTGGCCGAAGGAAAAG
ATTTAACGGCAATAAAACTTTTGGTTGGTACCGGAGGGGTGCTGACACGGTCTAAATACCGCTGGGAAGTAATGAAAACA
GTTTCCACACTTTCGAGACGCTATAATAGAGAACTGCTACCGCGACCCGAGGTGCGTGTTGCCAGTGATAAACACTATAT
TTTTGCGGCTTTGGGGGTCATCTCAACAGTTGATAGGACGGTGGCCAGGGAGCTATTGAAAGAGGATATAGAGTTTCATG
ATTGTTAA

Upstream 100 bases:

>100_bases
CTTGGGAAGATAATGAGAGAGATTATGCCAAAAGTCAAAGGAAGGGCCAACGGGAAAACAGTCAACAGAATCGTCAGGGA
GCTTCTGGAAAGCAAGTAAT

Downstream 100 bases:

>100_bases
ATCTTACAGAAAACAAATAAAGGGAGCATTTGCTCCCTTTATTGCTTTTATGGAGCGGGCGACGGGACTCGAACCCGCGA
CCCTCAGCTTGGGAAGCTGA

Product: glutamate mutase MutL

Products: L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKVDILTAEIGSTTTVLSAFISDGSGKMKFLGQGEFYTTVNEGDVTIGIEKAIDVLKHRLNESKLDYELLLATSSAAGGL
KMTVHGLVYDMTVKAAKEAALGAGAVIKYVTAGKMTEHDLEKVLEIDPRLILLAGGVDYGERETVLHNAEMLAKLPLNVP
IIYAGNITAAEEAQRVLEASGKEVLVTENVYPRIDQLNVEPTRKIIRDVFAKHIVKGPGMDKIYSIVGRNVIPTPAAVML
TTELLAEEYEDVLVVDIGGATTDVDSYTSGDPEIQKILIAPEPLAKRTVEGDLGVFVNAKNVIDYIGKDALMTEFNDFEE
IIREISPYPKNSRTETFISRLAKYCFETSIRRHAGRIRQLYGPLGRVEVAEGKDLTAIKLLVGTGGVLTRSKYRWEVMKT
VSTLSRRYNRELLPRPEVRVASDKHYIFAALGVISTVDRTVARELLKEDIEFHDC

Sequences:

>Translated_455_residues
MKVDILTAEIGSTTTVLSAFISDGSGKMKFLGQGEFYTTVNEGDVTIGIEKAIDVLKHRLNESKLDYELLLATSSAAGGL
KMTVHGLVYDMTVKAAKEAALGAGAVIKYVTAGKMTEHDLEKVLEIDPRLILLAGGVDYGERETVLHNAEMLAKLPLNVP
IIYAGNITAAEEAQRVLEASGKEVLVTENVYPRIDQLNVEPTRKIIRDVFAKHIVKGPGMDKIYSIVGRNVIPTPAAVML
TTELLAEEYEDVLVVDIGGATTDVDSYTSGDPEIQKILIAPEPLAKRTVEGDLGVFVNAKNVIDYIGKDALMTEFNDFEE
IIREISPYPKNSRTETFISRLAKYCFETSIRRHAGRIRQLYGPLGRVEVAEGKDLTAIKLLVGTGGVLTRSKYRWEVMKT
VSTLSRRYNRELLPRPEVRVASDKHYIFAALGVISTVDRTVARELLKEDIEFHDC
>Mature_455_residues
MKVDILTAEIGSTTTVLSAFISDGSGKMKFLGQGEFYTTVNEGDVTIGIEKAIDVLKHRLNESKLDYELLLATSSAAGGL
KMTVHGLVYDMTVKAAKEAALGAGAVIKYVTAGKMTEHDLEKVLEIDPRLILLAGGVDYGERETVLHNAEMLAKLPLNVP
IIYAGNITAAEEAQRVLEASGKEVLVTENVYPRIDQLNVEPTRKIIRDVFAKHIVKGPGMDKIYSIVGRNVIPTPAAVML
TTELLAEEYEDVLVVDIGGATTDVDSYTSGDPEIQKILIAPEPLAKRTVEGDLGVFVNAKNVIDYIGKDALMTEFNDFEE
IIREISPYPKNSRTETFISRLAKYCFETSIRRHAGRIRQLYGPLGRVEVAEGKDLTAIKLLVGTGGVLTRSKYRWEVMKT
VSTLSRRYNRELLPRPEVRVASDKHYIFAALGVISTVDRTVARELLKEDIEFHDC

Specific function: May play a role in glutamate fermentation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006230
- InterPro:   IPR002821 [H]

Pfam domain/function: PF01968 Hydantoinase_A [H]

EC number: 5.4.99.1

Molecular weight: Translated: 50146; Mature: 50146

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDILTAEIGSTTTVLSAFISDGSGKMKFLGQGEFYTTVNEGDVTIGIEKAIDVLKHRL
CEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCEEEEHHHHHHHHHHHH
NESKLDYELLLATSSAAGGLKMTVHGLVYDMTVKAAKEAALGAGAVIKYVTAGKMTEHDL
CCCCCCEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHH
EKVLEIDPRLILLAGGVDYGERETVLHNAEMLAKLPLNVPIIYAGNITAAEEAQRVLEAS
HHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
GKEVLVTENVYPRIDQLNVEPTRKIIRDVFAKHIVKGPGMDKIYSIVGRNVIPTPAAVML
CCEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHH
TTELLAEEYEDVLVVDIGGATTDVDSYTSGDPEIQKILIAPEPLAKRTVEGDLGVFVNAK
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCEEEEEHH
NVIDYIGKDALMTEFNDFEEIIREISPYPKNSRTETFISRLAKYCFETSIRRHAGRIRQL
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGPLGRVEVAEGKDLTAIKLLVGTGGVLTRSKYRWEVMKTVSTLSRRYNRELLPRPEVRV
HCCCCCEEECCCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
ASDKHYIFAALGVISTVDRTVARELLKEDIEFHDC
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVDILTAEIGSTTTVLSAFISDGSGKMKFLGQGEFYTTVNEGDVTIGIEKAIDVLKHRL
CEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCEEEEHHHHHHHHHHHH
NESKLDYELLLATSSAAGGLKMTVHGLVYDMTVKAAKEAALGAGAVIKYVTAGKMTEHDL
CCCCCCEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHH
EKVLEIDPRLILLAGGVDYGERETVLHNAEMLAKLPLNVPIIYAGNITAAEEAQRVLEAS
HHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
GKEVLVTENVYPRIDQLNVEPTRKIIRDVFAKHIVKGPGMDKIYSIVGRNVIPTPAAVML
CCEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHH
TTELLAEEYEDVLVVDIGGATTDVDSYTSGDPEIQKILIAPEPLAKRTVEGDLGVFVNAK
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCEEEEEHH
NVIDYIGKDALMTEFNDFEEIIREISPYPKNSRTETFISRLAKYCFETSIRRHAGRIRQL
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGPLGRVEVAEGKDLTAIKLLVGTGGVLTRSKYRWEVMKTVSTLSRRYNRELLPRPEVRV
HCCCCCEEECCCCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
ASDKHYIFAALGVISTVDRTVARELLKEDIEFHDC
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-threo-3-methylaspartate

Specific reaction: L-threo-3-methylaspartate = L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428631 [H]