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The map label for this gene is xylR [H]

Identifier: 239618366

GI number: 239618366

Start: 2127988

End: 2129148

Strand: Reverse

Name: xylR [H]

Synonym: Kole_2004

Alternate gene names: 239618366

Gene position: 2129148-2127988 (Counterclockwise)

Preceding gene: 239618367

Following gene: 239618365

Centisome position: 92.49

GC content: 38.33

Gene sequence:

>1161_bases
ATGCTTATACTGAAACCCAAAGATACACGAATTAAAAACGCTATTACTTTACTTCATATTTTATTGAAACAGGACGGCAT
TTCCAGAGTTGAGCTTTCGAGGATTACAGGGTTAACTAAGACGACTGTATCATCTATCATAAAGGAATTTTTAGCCGCTG
GAATAGTTGAAGAATCCCCGACAAAGCCAAACGGAAATGTCGGTAAAACACCTATCTCTTTGCATATCAAAAAGAACGCT
GTGTACACATTGGGAGTCCATCTTGGAAGACACAACATAAAAACGGTATTAATGGATGCCAGTATGAAAGTACTGATGGA
AAGCAATGGATTATCTTATAAAAAAAATGATCCAGACAGTGTTCTTGAAAAGCTCTATCTGGATATTAATCATATTATGG
AGAAAGCAGAAAAGCATGGGATTAAGGTTGGAGTTATAGGAATTGGAATCCCTGGTCCTCTTGATCCCGAAACTGGTGTT
ATAAAGTGTCCACCGAAATTTGAGGGATGGATAAATATTCCGCTTGGAGAGATCATACAAAAAAAATACAAACTGCCTGT
TTGGATAGAAAATGATGCGAATGTAGCTGCACTTGCGGAAAAGTGGCACGGTGGCGCAAAGTATCTAAAGAATTTCGTAT
ACATACTTGTGAATGAAGGAATTGGAGCCGGAGTTGTAATTAATGATGAACTTTATCAGGGAACCCATGACTATGTTGGA
GAAATAGGCCACAGCTTATTTTATGTTCATGGGCAATTTAAATATCTCGAAGATCTGTACGGAGTAGATGTATTGACAAG
CCAAATAAAGTCATGTGGATTGAATGCACACAGTATTGAAGATGTCGCGAATCTTCTCAAAGCTGACAACAAAATTGTAT
ATTCCATTGTACGCGATAGTGCCAAGTGGCTTTCTATTGTCGTTCTTAATGTCATACATTTATTAAATCCTCAGGCCGTC
TTTATTGGTGGGACAATGGCAGCATTGGGTAATTATCTAATCCAACCGGTAAAAGAAATAGTCTCTCAATATTTATTTGG
CGATCAGGAAACCGACGTGAAACTTTCGGAAATTTCAGACAATGCCGTGGCAATCGGAGCCGGAATTTACGCTACTGCAA
AATGGTTAGAGGCCAAAAGTATCGAACATGTACATCATTAG

Upstream 100 bases:

>100_bases
AGGTGTTAAAAGGACCCCGTGTTTTGTTGATATAATCCAATTAGTTAGTCCAGTTTACTAATTTATTCGTTAACTTGAAA
CTGATTCATTGGAGGAGTCT

Downstream 100 bases:

>100_bases
GGACAATCTTTTTTTAATACCCCATAAGGGGAAATCTTAAAGGGGAGGTAGTGTTATGAGAAAGTTCTTTGTTCTTTTGA
TGATTCTTTCAATGGCCTTT

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MLILKPKDTRIKNAITLLHILLKQDGISRVELSRITGLTKTTVSSIIKEFLAAGIVEESPTKPNGNVGKTPISLHIKKNA
VYTLGVHLGRHNIKTVLMDASMKVLMESNGLSYKKNDPDSVLEKLYLDINHIMEKAEKHGIKVGVIGIGIPGPLDPETGV
IKCPPKFEGWINIPLGEIIQKKYKLPVWIENDANVAALAEKWHGGAKYLKNFVYILVNEGIGAGVVINDELYQGTHDYVG
EIGHSLFYVHGQFKYLEDLYGVDVLTSQIKSCGLNAHSIEDVANLLKADNKIVYSIVRDSAKWLSIVVLNVIHLLNPQAV
FIGGTMAALGNYLIQPVKEIVSQYLFGDQETDVKLSEISDNAVAIGAGIYATAKWLEAKSIEHVHH

Sequences:

>Translated_386_residues
MLILKPKDTRIKNAITLLHILLKQDGISRVELSRITGLTKTTVSSIIKEFLAAGIVEESPTKPNGNVGKTPISLHIKKNA
VYTLGVHLGRHNIKTVLMDASMKVLMESNGLSYKKNDPDSVLEKLYLDINHIMEKAEKHGIKVGVIGIGIPGPLDPETGV
IKCPPKFEGWINIPLGEIIQKKYKLPVWIENDANVAALAEKWHGGAKYLKNFVYILVNEGIGAGVVINDELYQGTHDYVG
EIGHSLFYVHGQFKYLEDLYGVDVLTSQIKSCGLNAHSIEDVANLLKADNKIVYSIVRDSAKWLSIVVLNVIHLLNPQAV
FIGGTMAALGNYLIQPVKEIVSQYLFGDQETDVKLSEISDNAVAIGAGIYATAKWLEAKSIEHVHH
>Mature_386_residues
MLILKPKDTRIKNAITLLHILLKQDGISRVELSRITGLTKTTVSSIIKEFLAAGIVEESPTKPNGNVGKTPISLHIKKNA
VYTLGVHLGRHNIKTVLMDASMKVLMESNGLSYKKNDPDSVLEKLYLDINHIMEKAEKHGIKVGVIGIGIPGPLDPETGV
IKCPPKFEGWINIPLGEIIQKKYKLPVWIENDANVAALAEKWHGGAKYLKNFVYILVNEGIGAGVVINDELYQGTHDYVG
EIGHSLFYVHGQFKYLEDLYGVDVLTSQIKSCGLNAHSIEDVANLLKADNKIVYSIVRDSAKWLSIVVLNVIHLLNPQAV
FIGGTMAALGNYLIQPVKEIVSQYLFGDQETDVKLSEISDNAVAIGAGIYATAKWLEAKSIEHVHH

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=289, Percent_Identity=26.2975778546713, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4885285, Length=289, Percent_Identity=26.2975778546713, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI298566325, Length=289, Percent_Identity=26.2975778546713, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI190014632, Length=289, Percent_Identity=26.2975778546713, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787878, Length=373, Percent_Identity=25.201072386059, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786891, Length=384, Percent_Identity=22.65625, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082127, Length=374, Percent_Identity=22.9946524064171, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081733, Length=301, Percent_Identity=23.5880398671096, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42451; Mature: 42451

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILKPKDTRIKNAITLLHILLKQDGISRVELSRITGLTKTTVSSIIKEFLAAGIVEESP
CEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
TKPNGNVGKTPISLHIKKNAVYTLGVHLGRHNIKTVLMDASMKVLMESNGLSYKKNDPDS
CCCCCCCCCCCEEEEEECCEEEEEEEEECCCCHHHHEEHHHHEEEEECCCCCCCCCCHHH
VLEKLYLDINHIMEKAEKHGIKVGVIGIGIPGPLDPETGVIKCPPKFEGWINIPLGEIIQ
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCCCCEEECCHHHHHH
KKYKLPVWIENDANVAALAEKWHGGAKYLKNFVYILVNEGIGAGVVINDELYQGTHDYVG
HHCCCCEEEECCCCHHHHHHHHCCHHHHHHHEEEEEEECCCCCCEEECHHHHCCCHHHHH
EIGHSLFYVHGQFKYLEDLYGVDVLTSQIKSCGLNAHSIEDVANLLKADNKIVYSIVRDS
HHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEHHHHHHH
AKWLSIVVLNVIHLLNPQAVFIGGTMAALGNYLIQPVKEIVSQYLFGDQETDVKLSEISD
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHEECCC
NAVAIGAGIYATAKWLEAKSIEHVHH
CEEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLILKPKDTRIKNAITLLHILLKQDGISRVELSRITGLTKTTVSSIIKEFLAAGIVEESP
CEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
TKPNGNVGKTPISLHIKKNAVYTLGVHLGRHNIKTVLMDASMKVLMESNGLSYKKNDPDS
CCCCCCCCCCCEEEEEECCEEEEEEEEECCCCHHHHEEHHHHEEEEECCCCCCCCCCHHH
VLEKLYLDINHIMEKAEKHGIKVGVIGIGIPGPLDPETGVIKCPPKFEGWINIPLGEIIQ
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCCCCEEECCHHHHHH
KKYKLPVWIENDANVAALAEKWHGGAKYLKNFVYILVNEGIGAGVVINDELYQGTHDYVG
HHCCCCEEEECCCCHHHHHHHHCCHHHHHHHEEEEEEECCCCCCEEECHHHHCCCHHHHH
EIGHSLFYVHGQFKYLEDLYGVDVLTSQIKSCGLNAHSIEDVANLLKADNKIVYSIVRDS
HHCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEHHHHHHH
AKWLSIVVLNVIHLLNPQAVFIGGTMAALGNYLIQPVKEIVSQYLFGDQETDVKLSEISD
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHEECCC
NAVAIGAGIYATAKWLEAKSIEHVHH
CEEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]