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The map label for this gene is spoVD [H]

Identifier: 239618272

GI number: 239618272

Start: 2029832

End: 2031577

Strand: Reverse

Name: spoVD [H]

Synonym: Kole_1909

Alternate gene names: 239618272

Gene position: 2031577-2029832 (Counterclockwise)

Preceding gene: 239618273

Following gene: 239618271

Centisome position: 88.25

GC content: 40.95

Gene sequence:

>1746_bases
TTGCTCTCAAATGCAGATATTCCAACCGTTGTTAAAGTTAATCGTTTGCCTGCATTAAGAGGTTCCATTTATGATGCCAA
AGGAAGATTGTTAGCCAGCGATTCTTTGATCTACGAAGCCTGGCTTGACCTTGGTTATTTGAAAGAGACTGCATCTGAAA
GAGAAATCTCTGAAGTTCTCTCTTCGCTATCTGAAAATTTTGATATTCCTCCGGAAAAGTTGTCTTCCCTTCTGGATTCT
TCGGAGCGATTTTTCCTCGTAGAAAAATCACCAACACTAAAAGAACTTTCGCGCAAATTCAATCAAAGAACCAGAAAATT
TATTTCAATAGAGATTTCAACAGAACGCCACTATTTCGGGGAGTTCGGTCTCGACAAAATTATCGGAAAATTAGACAGTG
GCAAAAGTCCAATTAATGGAATAGAGAAAAAATATGACCACGTATTGAAAGGAAAGAAAGATGGCTACATACTCAGAACG
TTCTATGGATCTGAAAAATTTTCTCCTGTAAACGGAAACGATGTCTTCTTATCAATAGATATAGATGTGCAAAAGCTTGT
ATATCAGGAACTCAAAGAGGCAGTCAGAAAAAACAAAGCCGATGGCGGCCTTGTTATCCTGATGGAAGCGAAAACTGGAA
GGATCATCGCCTACGCTCAGACATATCAATGGGATAGGGGACTCCTCGGGATCTTCGAGCCTGGTTCAACGGTGAAACCT
ATAATATACGGCCTCGCTTTGAGCACTGAATCTATCACCGAAGAATCAACCTTCTTGTGCGAGGGAAAAATCCAACCAGT
AGAAGGATTAGATATAATAATCAGGGATACAGAAGGTGAAAAACACGGTATCGAAACTTTTAAGGATGCCATAAGAAACT
CCTGTAACGTCGCAACCGTTCAGGTAGCACAACGCTTGCTTGATAACCTCGGAAAATATGAAATATATAACAAACTTCTG
GAGGCAGGTTTTGGAAGACCAACCGGCATCGATCTTCCTGGCGAAACAAAAGGAATTCTTCCCAAACCAAACAAATGGTC
ACTTATATCACCCTACCAGTTTGCAATAGGACAGGGTATTGCAGTAAACGCTTTTCAACTTATTAGAGCATTGAATGTAT
ATCCTTCGGGTGGGTACCTGTTGGTTCCCTCTTTCGTTAAGGCGCTTGGTGAAGAACACGAGATAGTAAAAATTGAACCA
AAGATAGAAAAGTCTCTTTTTCCGCCTTATATAGTCGAAATGATACGCCCTGTTCTGGAATCAGTTGTCGCAAGCGGTAC
CGGGATAAGGGCACAGGTTGAAGGAATAAAGGTGGCTGGCAAAACTGGAACTGCCCAAAGAGCTACTTCAGAAGGATACA
GTTCAACTGAGTTTAATTCGCTTTTCTGGGGATATTTTCCGGCAGATGATCCGAAATATTCTTTGTTAGTACTAATTGAA
AACCCTAAAGCTGGTGAGTATTACGGTGGTACCGTAGCAGGTCCTGTGTTTTCCTCAATAGTTAAAAAATTATACTTCCC
CGATAACGAAAAGAATAAGATCGTTCCCATATACCCGTGGAAGATGCCGAATCTTTTAGGTTATACTTTACATGATGTAA
TGGAAATATCCAGGCTCTTTGGCATAAGCAAGGTAGAGGTTCACGGCACGGGAAAAGTTGTTTCACAAATACCAGCCCCC
GGAGAAAAATTCATAGATCCTCCATATAAAATGGAGGTCTGGCTTTCAGTAAGGGAGAGTGAATGA

Upstream 100 bases:

>100_bases
TGCTGGCAAAATCAACAATCTCGTTAGACGAACTATTATTGTCTTTATAGCGGTTCTGCTGGTAACTCTGATTTTCAGCA
TCAGAGTTATAAAGTGTGCG

Downstream 100 bases:

>100_bases
TAATTGCTGTATTGTCTTAAAGGTAATAGCGAAGTATTGAAAAGGCTATTCATTGAAGAAAAAGCAAAAAAACATGTAGT
GCTCTGGCCACAGGACGATG

Product: Peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MLSNADIPTVVKVNRLPALRGSIYDAKGRLLASDSLIYEAWLDLGYLKETASEREISEVLSSLSENFDIPPEKLSSLLDS
SERFFLVEKSPTLKELSRKFNQRTRKFISIEISTERHYFGEFGLDKIIGKLDSGKSPINGIEKKYDHVLKGKKDGYILRT
FYGSEKFSPVNGNDVFLSIDIDVQKLVYQELKEAVRKNKADGGLVILMEAKTGRIIAYAQTYQWDRGLLGIFEPGSTVKP
IIYGLALSTESITEESTFLCEGKIQPVEGLDIIIRDTEGEKHGIETFKDAIRNSCNVATVQVAQRLLDNLGKYEIYNKLL
EAGFGRPTGIDLPGETKGILPKPNKWSLISPYQFAIGQGIAVNAFQLIRALNVYPSGGYLLVPSFVKALGEEHEIVKIEP
KIEKSLFPPYIVEMIRPVLESVVASGTGIRAQVEGIKVAGKTGTAQRATSEGYSSTEFNSLFWGYFPADDPKYSLLVLIE
NPKAGEYYGGTVAGPVFSSIVKKLYFPDNEKNKIVPIYPWKMPNLLGYTLHDVMEISRLFGISKVEVHGTGKVVSQIPAP
GEKFIDPPYKMEVWLSVRESE

Sequences:

>Translated_581_residues
MLSNADIPTVVKVNRLPALRGSIYDAKGRLLASDSLIYEAWLDLGYLKETASEREISEVLSSLSENFDIPPEKLSSLLDS
SERFFLVEKSPTLKELSRKFNQRTRKFISIEISTERHYFGEFGLDKIIGKLDSGKSPINGIEKKYDHVLKGKKDGYILRT
FYGSEKFSPVNGNDVFLSIDIDVQKLVYQELKEAVRKNKADGGLVILMEAKTGRIIAYAQTYQWDRGLLGIFEPGSTVKP
IIYGLALSTESITEESTFLCEGKIQPVEGLDIIIRDTEGEKHGIETFKDAIRNSCNVATVQVAQRLLDNLGKYEIYNKLL
EAGFGRPTGIDLPGETKGILPKPNKWSLISPYQFAIGQGIAVNAFQLIRALNVYPSGGYLLVPSFVKALGEEHEIVKIEP
KIEKSLFPPYIVEMIRPVLESVVASGTGIRAQVEGIKVAGKTGTAQRATSEGYSSTEFNSLFWGYFPADDPKYSLLVLIE
NPKAGEYYGGTVAGPVFSSIVKKLYFPDNEKNKIVPIYPWKMPNLLGYTLHDVMEISRLFGISKVEVHGTGKVVSQIPAP
GEKFIDPPYKMEVWLSVRESE
>Mature_581_residues
MLSNADIPTVVKVNRLPALRGSIYDAKGRLLASDSLIYEAWLDLGYLKETASEREISEVLSSLSENFDIPPEKLSSLLDS
SERFFLVEKSPTLKELSRKFNQRTRKFISIEISTERHYFGEFGLDKIIGKLDSGKSPINGIEKKYDHVLKGKKDGYILRT
FYGSEKFSPVNGNDVFLSIDIDVQKLVYQELKEAVRKNKADGGLVILMEAKTGRIIAYAQTYQWDRGLLGIFEPGSTVKP
IIYGLALSTESITEESTFLCEGKIQPVEGLDIIIRDTEGEKHGIETFKDAIRNSCNVATVQVAQRLLDNLGKYEIYNKLL
EAGFGRPTGIDLPGETKGILPKPNKWSLISPYQFAIGQGIAVNAFQLIRALNVYPSGGYLLVPSFVKALGEEHEIVKIEP
KIEKSLFPPYIVEMIRPVLESVVASGTGIRAQVEGIKVAGKTGTAQRATSEGYSSTEFNSLFWGYFPADDPKYSLLVLIE
NPKAGEYYGGTVAGPVFSSIVKKLYFPDNEKNKIVPIYPWKMPNLLGYTLHDVMEISRLFGISKVEVHGTGKVVSQIPAP
GEKFIDPPYKMEVWLSVRESE

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=521, Percent_Identity=28.2149712092131, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786854, Length=593, Percent_Identity=21.7537942664418, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 64695; Mature: 64695

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNADIPTVVKVNRLPALRGSIYDAKGRLLASDSLIYEAWLDLGYLKETASEREISEVL
CCCCCCCCCEEEECCCCCHHCCEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLSENFDIPPEKLSSLLDSSERFFLVEKSPTLKELSRKFNQRTRKFISIEISTERHYFG
HHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCCCC
EFGLDKIIGKLDSGKSPINGIEKKYDHVLKGKKDGYILRTFYGSEKFSPVNGNDVFLSID
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEE
IDVQKLVYQELKEAVRKNKADGGLVILMEAKTGRIIAYAQTYQWDRGLLGIFEPGSTVKP
CCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEECCCCCCCH
IIYGLALSTESITEESTFLCEGKIQPVEGLDIIIRDTEGEKHGIETFKDAIRNSCNVATV
HHHEEEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHH
QVAQRLLDNLGKYEIYNKLLEAGFGRPTGIDLPGETKGILPKPNKWSLISPYQFAIGQGI
HHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHCCCC
AVNAFQLIRALNVYPSGGYLLVPSFVKALGEEHEIVKIEPKIEKSLFPPYIVEMIRPVLE
CHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCEEEECCCHHHHCCCHHHHHHHHHHHH
SVVASGTGIRAQVEGIKVAGKTGTAQRATSEGYSSTEFNSLFWGYFPADDPKYSLLVLIE
HHHHCCCCCEEEEEEEEEECCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEE
NPKAGEYYGGTVAGPVFSSIVKKLYFPDNEKNKIVPIYPWKMPNLLGYTLHDVMEISRLF
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
GISKVEVHGTGKVVSQIPAPGEKFIDPPYKMEVWLSVRESE
CCEEEEEECCCHHHHHCCCCCHHHCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MLSNADIPTVVKVNRLPALRGSIYDAKGRLLASDSLIYEAWLDLGYLKETASEREISEVL
CCCCCCCCCEEEECCCCCHHCCEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLSENFDIPPEKLSSLLDSSERFFLVEKSPTLKELSRKFNQRTRKFISIEISTERHYFG
HHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCCCC
EFGLDKIIGKLDSGKSPINGIEKKYDHVLKGKKDGYILRTFYGSEKFSPVNGNDVFLSID
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEE
IDVQKLVYQELKEAVRKNKADGGLVILMEAKTGRIIAYAQTYQWDRGLLGIFEPGSTVKP
CCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCEEEECCCCCCCH
IIYGLALSTESITEESTFLCEGKIQPVEGLDIIIRDTEGEKHGIETFKDAIRNSCNVATV
HHHEEEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHH
QVAQRLLDNLGKYEIYNKLLEAGFGRPTGIDLPGETKGILPKPNKWSLISPYQFAIGQGI
HHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHCCCC
AVNAFQLIRALNVYPSGGYLLVPSFVKALGEEHEIVKIEPKIEKSLFPPYIVEMIRPVLE
CHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCCCEEEECCCHHHHCCCHHHHHHHHHHHH
SVVASGTGIRAQVEGIKVAGKTGTAQRATSEGYSSTEFNSLFWGYFPADDPKYSLLVLIE
HHHHCCCCCEEEEEEEEEECCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEE
NPKAGEYYGGTVAGPVFSSIVKKLYFPDNEKNKIVPIYPWKMPNLLGYTLHDVMEISRLF
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
GISKVEVHGTGKVVSQIPAPGEKFIDPPYKMEVWLSVRESE
CCEEEEEECCCHHHHHCCCCCHHHCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]