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The map label for this gene is mcrC [C]

Identifier: 239618177

GI number: 239618177

Start: 1937947

End: 1939140

Strand: Direct

Name: mcrC [C]

Synonym: Kole_1813

Alternate gene names: 239618177

Gene position: 1937947-1939140 (Clockwise)

Preceding gene: 239618176

Following gene: 239618180

Centisome position: 84.18

GC content: 39.36

Gene sequence:

>1194_bases
TTGACAGTGAAAAACATCATCGAATTGAAGGAATACAAAAAGAAGATAGTGCCAAAAGAGGATCTACCCAACGAACTTGG
AGCGTTTCTCTGGCGTGAAAATGGTAACAAAATAAACGTTGAGTTTCCGACCCTTAAGACCGCTAATAACTGGGAGCTGA
CTTCAAACGGGTGGGTTGGATACATTCCTTTATCACAAGAATATGGTCTCAGGTTGCTTCCGAGAGTTGAGCTTAAAAAC
CTTCTCCACATGCTCGAGTACGCGTATAATTTGAAATCATTTCAATTTATTGAAGGCATCCAGGATTGTGAGACTATTGA
AGAGTTATATGAAAGACTGGTCAAGGTTTTTGTGAAACGTGTTATAGATCGTACAAAGAGAGGCTTGTACAGAGAATACA
TTCAACAAAACGATAGATTACCATATGTGAGGGGAAAATTAAATGTTCGGTCGATGATAAAGCAGCCCTGGAAAGTAAAG
CTCGATTGTGTTTATCAGGATCATACGAACGATATTGAGGAAAACCAGATAATACTCTGGACTCTTTCGAAGCTAGTCAT
GAGTGACAGCATAAGTGAAGGAACGAGGAATCTTGTCAGAAAAGCGTACAGATCTCTGGCAGGAACTATCAAAGTCAGGC
CTTTCAAACCTTCAGAATGTATAAAAAGATTCTATAACAGATTGAACAGCGACTATCTTCCCATACATGTTCTTGCAAAG
TTCTTCCTTGAAAATAGCGGTCCTGCAGTAAAGTCTGGAACCAGTAAGATGATTCCTTTTCTCGTGAATATGCCCCGGTT
GTTTGAGAAGTTCATTGCCGAATGGTTGAAGAAGAATTTGAAAGGGTATATAGTACGTGCTCAGGAGAAGGTCAATTTAG
ATAAAGAAAATAGCCTGAGTTTTAATATCGATCTTGTCATCTATAGTGGATTAACAGGAGAAGCCGTTGCTGTTTTGGAT
ACGAAGTATAAAATCAATGAACGTCCTTCGGATAACGATATATCTCAGATAGCCAGTTACGCTATGACAAAGAACTGCAC
AAAGGCTTTTTTGATTTATCCGATAGACATGAATCCACCGGTGAATGTTACCGTTGGAAGTGTCGCTATCAGATGTCTTA
CTTTCCAGCTTTCGGGAGATCTTGAAGCAAATGGCATGAGAATGGTGGATGAACTGATGAGATTTATTGAATAG

Upstream 100 bases:

>100_bases
AAATACTTCCTTATCTTGAGGAATATTTCTTTGACCAACCTGAAAAAGTGGATGAGTTCAAATGGGAAAAGGTAAAGACT
GAAATTTTGGGGGAAGATAG

Downstream 100 bases:

>100_bases
AATAGTAAACCAGGGACAATGTCCCTGGTTTTAGTTTGTTGATTGAAGATAAAACTCAGTAGATTAATCAAAACTCTTTT
TTCCATGGCACAAGGAAGTT

Product: McrBC 5-methylcytosine restriction system component-like protein

Products: NA

Alternate protein names: McrBC 5-Methylcytosine Restriction System Component; 5-Methylcytosine Restriction System Component- Like Protein; McrBC 5-Methylcytosine Restriction System Component-Like; Restriction Modulator Protein; McrBC Restriction Endonuclease System Subunit McrC

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTVKNIIELKEYKKKIVPKEDLPNELGAFLWRENGNKINVEFPTLKTANNWELTSNGWVGYIPLSQEYGLRLLPRVELKN
LLHMLEYAYNLKSFQFIEGIQDCETIEELYERLVKVFVKRVIDRTKRGLYREYIQQNDRLPYVRGKLNVRSMIKQPWKVK
LDCVYQDHTNDIEENQIILWTLSKLVMSDSISEGTRNLVRKAYRSLAGTIKVRPFKPSECIKRFYNRLNSDYLPIHVLAK
FFLENSGPAVKSGTSKMIPFLVNMPRLFEKFIAEWLKKNLKGYIVRAQEKVNLDKENSLSFNIDLVIYSGLTGEAVAVLD
TKYKINERPSDNDISQIASYAMTKNCTKAFLIYPIDMNPPVNVTVGSVAIRCLTFQLSGDLEANGMRMVDELMRFIE

Sequences:

>Translated_397_residues
MTVKNIIELKEYKKKIVPKEDLPNELGAFLWRENGNKINVEFPTLKTANNWELTSNGWVGYIPLSQEYGLRLLPRVELKN
LLHMLEYAYNLKSFQFIEGIQDCETIEELYERLVKVFVKRVIDRTKRGLYREYIQQNDRLPYVRGKLNVRSMIKQPWKVK
LDCVYQDHTNDIEENQIILWTLSKLVMSDSISEGTRNLVRKAYRSLAGTIKVRPFKPSECIKRFYNRLNSDYLPIHVLAK
FFLENSGPAVKSGTSKMIPFLVNMPRLFEKFIAEWLKKNLKGYIVRAQEKVNLDKENSLSFNIDLVIYSGLTGEAVAVLD
TKYKINERPSDNDISQIASYAMTKNCTKAFLIYPIDMNPPVNVTVGSVAIRCLTFQLSGDLEANGMRMVDELMRFIE
>Mature_396_residues
TVKNIIELKEYKKKIVPKEDLPNELGAFLWRENGNKINVEFPTLKTANNWELTSNGWVGYIPLSQEYGLRLLPRVELKNL
LHMLEYAYNLKSFQFIEGIQDCETIEELYERLVKVFVKRVIDRTKRGLYREYIQQNDRLPYVRGKLNVRSMIKQPWKVKL
DCVYQDHTNDIEENQIILWTLSKLVMSDSISEGTRNLVRKAYRSLAGTIKVRPFKPSECIKRFYNRLNSDYLPIHVLAKF
FLENSGPAVKSGTSKMIPFLVNMPRLFEKFIAEWLKKNLKGYIVRAQEKVNLDKENSLSFNIDLVIYSGLTGEAVAVLDT
KYKINERPSDNDISQIASYAMTKNCTKAFLIYPIDMNPPVNVTVGSVAIRCLTFQLSGDLEANGMRMVDELMRFIE

Specific function: Modifies The Specificity Of Mcrb Restriction By Expanding The Range Of Modified Sequences Restricted. Does Not Bind To DNA. [C]

COG id: COG4268

COG function: function code V; McrBC 5-methylcytosine restriction system component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46123; Mature: 45992

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKNIIELKEYKKKIVPKEDLPNELGAFLWRENGNKINVEFPTLKTANNWELTSNGWVG
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCEECCCCCEEECCCEEE
YIPLSQEYGLRLLPRVELKNLLHMLEYAYNLKSFQFIEGIQDCETIEELYERLVKVFVKR
EEECCCCCCCEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIDRTKRGLYREYIQQNDRLPYVRGKLNVRSMIKQPWKVKLDCVYQDHTNDIEENQIILW
HHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHCCCCEEEEEEEEECCCCCCCCCEEEEE
TLSKLVMSDSISEGTRNLVRKAYRSLAGTIKVRPFKPSECIKRFYNRLNSDYLPIHVLAK
EHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHH
FFLENSGPAVKSGTSKMIPFLVNMPRLFEKFIAEWLKKNLKGYIVRAQEKVNLDKENSLS
HHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCEE
FNIDLVIYSGLTGEAVAVLDTKYKINERPSDNDISQIASYAMTKNCTKAFLIYPIDMNPP
EEEEEEEEECCCCCEEEEEECCEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
VNVTVGSVAIRCLTFQLSGDLEANGMRMVDELMRFIE
CCEEHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TVKNIIELKEYKKKIVPKEDLPNELGAFLWRENGNKINVEFPTLKTANNWELTSNGWVG
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCEECCCCCEEECCCEEE
YIPLSQEYGLRLLPRVELKNLLHMLEYAYNLKSFQFIEGIQDCETIEELYERLVKVFVKR
EEECCCCCCCEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIDRTKRGLYREYIQQNDRLPYVRGKLNVRSMIKQPWKVKLDCVYQDHTNDIEENQIILW
HHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHCCCCEEEEEEEEECCCCCCCCCEEEEE
TLSKLVMSDSISEGTRNLVRKAYRSLAGTIKVRPFKPSECIKRFYNRLNSDYLPIHVLAK
EHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHH
FFLENSGPAVKSGTSKMIPFLVNMPRLFEKFIAEWLKKNLKGYIVRAQEKVNLDKENSLS
HHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCEE
FNIDLVIYSGLTGEAVAVLDTKYKINERPSDNDISQIASYAMTKNCTKAFLIYPIDMNPP
EEEEEEEEECCCCCEEEEEECCEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
VNVTVGSVAIRCLTFQLSGDLEANGMRMVDELMRFIE
CCEEHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA