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The map label for this gene is dgk [H]

Identifier: 239618036

GI number: 239618036

Start: 1794770

End: 1795387

Strand: Direct

Name: dgk [H]

Synonym: Kole_1665

Alternate gene names: 239618036

Gene position: 1794770-1795387 (Clockwise)

Preceding gene: 239618035

Following gene: 239618037

Centisome position: 77.96

GC content: 43.53

Gene sequence:

>618_bases
GTGTTCACGAAGTTTAGAGGAAAATATGTAGCAATTGAAGGGGTTATCGGGGTAGGAAAGACAACGCTCGTGAGGTATCT
CTCTCAAGAGTATGCACTGCCGCCAGTTCTTGAGGTTGTTGAAGAAAACCCTTTTCTATCGAAGTTTTATGAAGACATGG
AACGTTGGGCTTTTCAGACCCAACTTTTCTTTCTTGTGAGCAGGTTCGATCAGCAGGAGAAGTTGAAGAAAACTCTTCAG
ATGGGAATGGGTGCTGTTTCTGATTATATATTTGATAAGGACAGGCTCTTCGCCAGCCTGACTCTGAAAGGTGAGCATCT
AGGCCTTTATGAAAGAATTTTTGGGCTTCTCAAGAGCCACACGCCCACGCCGGACCTGGTTGTTTATCTTTATGCAGATA
TTGATGTTCTCATGGAAAGGATTGCTTTGAGGGATCGACCTTTCGAAAGAAGCATGGATAGAGGTTATATTTCGAACCTT
GCCGAAGCCTATGAAAGCTTTTTTGGGAACTACGCATGCGCGCCGGTGTTGAAAATCGATACGACAGAAATGGACTTTGT
GAGAAACCACAGTGATCTCAAAAAGATATACTCGTTGATAGAGGAGAGATTACCATGA

Upstream 100 bases:

>100_bases
TGTATCCCGGGGTTTGTGGAATCAGTGTCGTGGCTTTTAGAGCCTATTCTGGATAGTTTGAAGGTGCTAATAGATCAACT
GAATCAGGAGGACGGATAAG

Downstream 100 bases:

>100_bases
TAATAGGTATTTGCGGAAATATAGGAGCCGGGAAATCTTCTTTGACATCGCTTTTACAAAAAGAATTGGGATTTACAGCC
GTTTACGAAGCGGTAGATGA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MFTKFRGKYVAIEGVIGVGKTTLVRYLSQEYALPPVLEVVEENPFLSKFYEDMERWAFQTQLFFLVSRFDQQEKLKKTLQ
MGMGAVSDYIFDKDRLFASLTLKGEHLGLYERIFGLLKSHTPTPDLVVYLYADIDVLMERIALRDRPFERSMDRGYISNL
AEAYESFFGNYACAPVLKIDTTEMDFVRNHSDLKKIYSLIEERLP

Sequences:

>Translated_205_residues
MFTKFRGKYVAIEGVIGVGKTTLVRYLSQEYALPPVLEVVEENPFLSKFYEDMERWAFQTQLFFLVSRFDQQEKLKKTLQ
MGMGAVSDYIFDKDRLFASLTLKGEHLGLYERIFGLLKSHTPTPDLVVYLYADIDVLMERIALRDRPFERSMDRGYISNL
AEAYESFFGNYACAPVLKIDTTEMDFVRNHSDLKKIYSLIEERLP
>Mature_205_residues
MFTKFRGKYVAIEGVIGVGKTTLVRYLSQEYALPPVLEVVEENPFLSKFYEDMERWAFQTQLFFLVSRFDQQEKLKKTLQ
MGMGAVSDYIFDKDRLFASLTLKGEHLGLYERIFGLLKSHTPTPDLVVYLYADIDVLMERIALRDRPFERSMDRGYISNL
AEAYESFFGNYACAPVLKIDTTEMDFVRNHSDLKKIYSLIEERLP

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 23920; Mature: 23920

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTKFRGKYVAIEGVIGVGKTTLVRYLSQEYALPPVLEVVEENPFLSKFYEDMERWAFQT
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
QLFFLVSRFDQQEKLKKTLQMGMGAVSDYIFDKDRLFASLTLKGEHLGLYERIFGLLKSH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCC
TPTPDLVVYLYADIDVLMERIALRDRPFERSMDRGYISNLAEAYESFFGNYACAPVLKID
CCCCHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
TTEMDFVRNHSDLKKIYSLIEERLP
CCHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTKFRGKYVAIEGVIGVGKTTLVRYLSQEYALPPVLEVVEENPFLSKFYEDMERWAFQT
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
QLFFLVSRFDQQEKLKKTLQMGMGAVSDYIFDKDRLFASLTLKGEHLGLYERIFGLLKSH
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCC
TPTPDLVVYLYADIDVLMERIALRDRPFERSMDRGYISNLAEAYESFFGNYACAPVLKID
CCCCHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
TTEMDFVRNHSDLKKIYSLIEERLP
CCHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]