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The map label for this gene is groES

Identifier: 239617998

GI number: 239617998

Start: 1745333

End: 1745602

Strand: Direct

Name: groES

Synonym: Kole_1626

Alternate gene names: 239617998

Gene position: 1745333-1745602 (Clockwise)

Preceding gene: 239617997

Following gene: 239617999

Centisome position: 75.81

GC content: 40.74

Gene sequence:

>270_bases
ATGAAGGTTATTCCACTCGGAGAGAGACTTCTCATCAAGCCAATAAAGGAAGAGAAAAGAACAGAGGGCGGTATTGTTCT
TCCCGATACTGCCAAAGAGAAACCGATGAAGGCAGAGGTTATTGAAATTGGTAAGGACGTCGAGGATATCGATATCAAAG
TTGGCGATAAGGTTATATTTTCCAAATACGCCGGTACTGAGATCAAGATCGATGACGAAGACTATATATTGATTGATCAG
GATGATATTCTTGCCAAAGTCGAAGAATGA

Upstream 100 bases:

>100_bases
AGAATAACTATGTCTGGTTTATCATTAAATTAGCAGACTCATATAAAGAGTGCTAATTTATAAAAATCAGAATTTATAAA
AGTCGAAAGGAGGTAACAGT

Downstream 100 bases:

>100_bases
AAGGGGGTAGTGTGAATGCCAAAGATTCTTAAATTCAGTGAAGAAGCGAGAAGGTCTCTCGAAAGAGGTGTTGACGCTGT
TGCAGAAGCTGTTAAGATAA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MKVIPLGERLLIKPIKEEKRTEGGIVLPDTAKEKPMKAEVIEIGKDVEDIDIKVGDKVIFSKYAGTEIKIDDEDYILIDQ
DDILAKVEE

Sequences:

>Translated_89_residues
MKVIPLGERLLIKPIKEEKRTEGGIVLPDTAKEKPMKAEVIEIGKDVEDIDIKVGDKVIFSKYAGTEIKIDDEDYILIDQ
DDILAKVEE
>Mature_89_residues
MKVIPLGERLLIKPIKEEKRTEGGIVLPDTAKEKPMKAEVIEIGKDVEDIDIKVGDKVIFSKYAGTEIKIDDEDYILIDQ
DDILAKVEE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=92, Percent_Identity=36.9565217391304, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI169210012, Length=92, Percent_Identity=36.9565217391304, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=37.5, Blast_Score=60, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324594, Length=96, Percent_Identity=32.2916666666667, Blast_Score=59, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=36.4583333333333, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_KOSOT (C5CF51)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941320.1
- GeneID:   7967860
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1626
- ProtClustDB:   PRK14533
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10039; Mature: 10039

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIPLGERLLIKPIKEEKRTEGGIVLPDTAKEKPMKAEVIEIGKDVEDIDIKVGDKVIF
CCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCEEEEEECCEEEE
SKYAGTEIKIDDEDYILIDQDDILAKVEE
EECCCCEEEECCCCEEEEECCCCEEEECC
>Mature Secondary Structure
MKVIPLGERLLIKPIKEEKRTEGGIVLPDTAKEKPMKAEVIEIGKDVEDIDIKVGDKVIF
CCCCCCCCCEEEECCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCEEEEEECCEEEE
SKYAGTEIKIDDEDYILIDQDDILAKVEE
EECCCCEEEECCCCEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA