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The map label for this gene is folE2

Identifier: 239617842

GI number: 239617842

Start: 1566573

End: 1567346

Strand: Direct

Name: folE2

Synonym: Kole_1468

Alternate gene names: 239617842

Gene position: 1566573-1567346 (Clockwise)

Preceding gene: 239617841

Following gene: 239617843

Centisome position: 68.05

GC content: 39.92

Gene sequence:

>774_bases
ATGAGAGATGTACAGAGCGAAAAGGATCACAGAAATATTCCAATAAATATGGTTGGGATAAAAGGATTGAAATACCCCAT
CATTGTTATGGATAGAACCAATAAAAGGCAACATACCATAGGCACTTTCAATCTTTTTGTTGATCTGCCCAAGGATTTTC
GCGGTACCCATATGTCAAGGTTCGTTGAGGTTCTGGACAGGCATAACATGAAAGTGACACCAAAAAACATGGAATCTATC
CTTGATGACATGCGAGAAGCTCTGAAGGCCACGGTTGCACATGTTACTGTAGATTTTCCGTATTTCATAAGAAAGAACGC
ACCTATAAGTGGAATAGGAAGCTACAGCAGTTATAATTGCGGTTTTATTTCCACGAAAAACAAAGAATTCGATTTTATCC
TGAAAGTAGAGGTTCCTGTGCTCACGGTATGCCCCTGTTCTAAAGAGATTAGCGATCGAGGAGCGCATAATCAAAGGGCT
ATGGTGAATGTGCAGGTAAGAATGAATTCCCTCGTGTGGATAGAAGAAATAATAGAAATGGTGGAAGATGCTGCCAGCGC
TCCCATTTTTACTCTTCTCAAAAGGGAAGATGAAAAATTCATTACAGAAGTTTCTTACGATAATCCAAGATTTGTTGAGG
ATGTTTCTCGAGAGGTTGTTCTAAGGTTCATGAATGATCCCAGAATAAGCTGGTATAGAGTGGAGGTTTCAAGTCAGGAA
TCGATTCATAATCATGAGGCGTATGCCTGCATCGAAAAGGGTAAATCGTTATGA

Upstream 100 bases:

>100_bases
CCGGTTTTCAAGACCGGCTCCTTAGCCAATTAGGATACGCCTCCACGCCATCATGTGTCATTATAACTCAAAAAGATAAC
GGTATCAAGGGGTAATAATT

Downstream 100 bases:

>100_bases
TCGAACTCGACGAAAAAAAGGAAGAGCTTCTCACACGATTCTTAAAAGAGATTATTTCTTCAAAACACAATCTTACAGCT
ATAAAAGACTTTAAACAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRDVQSEKDHRNIPINMVGIKGLKYPIIVMDRTNKRQHTIGTFNLFVDLPKDFRGTHMSRFVEVLDRHNMKVTPKNMESI
LDDMREALKATVAHVTVDFPYFIRKNAPISGIGSYSSYNCGFISTKNKEFDFILKVEVPVLTVCPCSKEISDRGAHNQRA
MVNVQVRMNSLVWIEEIIEMVEDAASAPIFTLLKREDEKFITEVSYDNPRFVEDVSREVVLRFMNDPRISWYRVEVSSQE
SIHNHEAYACIEKGKSL

Sequences:

>Translated_257_residues
MRDVQSEKDHRNIPINMVGIKGLKYPIIVMDRTNKRQHTIGTFNLFVDLPKDFRGTHMSRFVEVLDRHNMKVTPKNMESI
LDDMREALKATVAHVTVDFPYFIRKNAPISGIGSYSSYNCGFISTKNKEFDFILKVEVPVLTVCPCSKEISDRGAHNQRA
MVNVQVRMNSLVWIEEIIEMVEDAASAPIFTLLKREDEKFITEVSYDNPRFVEDVSREVVLRFMNDPRISWYRVEVSSQE
SIHNHEAYACIEKGKSL
>Mature_257_residues
MRDVQSEKDHRNIPINMVGIKGLKYPIIVMDRTNKRQHTIGTFNLFVDLPKDFRGTHMSRFVEVLDRHNMKVTPKNMESI
LDDMREALKATVAHVTVDFPYFIRKNAPISGIGSYSSYNCGFISTKNKEFDFILKVEVPVLTVCPCSKEISDRGAHNQRA
MVNVQVRMNSLVWIEEIIEMVEDAASAPIFTLLKREDEKFITEVSYDNPRFVEDVSREVVLRFMNDPRISWYRVEVSSQE
SIHNHEAYACIEKGKSL

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_KOSOT (C5CEC0)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941164.1
- ProteinModelPortal:   C5CEC0
- GeneID:   7969111
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1468
- ProtClustDB:   CLSK975822
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 29721; Mature: 29721

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDVQSEKDHRNIPINMVGIKGLKYPIIVMDRTNKRQHTIGTFNLFVDLPKDFRGTHMSR
CCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCCHHHHH
FVEVLDRHNMKVTPKNMESILDDMREALKATVAHVTVDFPYFIRKNAPISGIGSYSSYNC
HHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCCCCCCCCCCC
GFISTKNKEFDFILKVEVPVLTVCPCSKEISDRGAHNQRAMVNVQVRMNSLVWIEEIIEM
CEEECCCCCEEEEEEEECCEEEECCCCHHHHHCCCCCCEEEEEEEEEECHHHHHHHHHHH
VEDAASAPIFTLLKREDEKFITEVSYDNPRFVEDVSREVVLRFMNDPRISWYRVEVSSQE
HHHHCCCCHHHHHHHCCHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCH
SIHNHEAYACIEKGKSL
HHHCHHHHHHHHCCCCC
>Mature Secondary Structure
MRDVQSEKDHRNIPINMVGIKGLKYPIIVMDRTNKRQHTIGTFNLFVDLPKDFRGTHMSR
CCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEEEEEEECCCCCCCHHHHH
FVEVLDRHNMKVTPKNMESILDDMREALKATVAHVTVDFPYFIRKNAPISGIGSYSSYNC
HHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCCCCCCCCCCC
GFISTKNKEFDFILKVEVPVLTVCPCSKEISDRGAHNQRAMVNVQVRMNSLVWIEEIIEM
CEEECCCCCEEEEEEEECCEEEECCCCHHHHHCCCCCCEEEEEEEEEECHHHHHHHHHHH
VEDAASAPIFTLLKREDEKFITEVSYDNPRFVEDVSREVVLRFMNDPRISWYRVEVSSQE
HHHHCCCCHHHHHHHCCHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCH
SIHNHEAYACIEKGKSL
HHHCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA