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The map label for this gene is tdk [H]

Identifier: 239617833

GI number: 239617833

Start: 1560655

End: 1561221

Strand: Direct

Name: tdk [H]

Synonym: Kole_1459

Alternate gene names: 239617833

Gene position: 1560655-1561221 (Clockwise)

Preceding gene: 239617832

Following gene: 239617834

Centisome position: 67.79

GC content: 38.27

Gene sequence:

>567_bases
ATGATAGGGAAGCTCACTTTGATCGTAGGGCCGATGTATTCCGGAAAAACTTCTGAATTGTTGTCACTAGTTGAAATATA
CTCTCTTGGAAAAAAGAAATACCTGGTTTTCAAGCCTGAAATCGATACTAGATATTCTGTCGATCATGTTGTAAGCCATA
CCGGGCAAAAAGTTCCAGCAATAACTATTCCAAGTGCCAGCAAATTGTTAGAAAAATTCGACGACATAAATGAAAAACTC
GACGCAATTTTCATTGATGAGGTCCATTTCTTTGATATCGACATTATTGATGTCATCAAAAAAATTATCCTTAAAGGTGT
CGATGTCTTTTGTGTTGGACTTGACATGAGCTATAAGCACAGACCGTTCCAGACCACTGCATCTCTTATGGCAATAGCAG
ATGAGGTTATAAAGAAAAAGGCCGTTTGCCATGTCTGTGGGGAGTATAAAGCAGTTGTTTCTCATAAAACGGTCAACAAT
TCTGGAAGCGAAATTGATGTTGGCGGAATGGAAAAATACATTGCTGTATGCAGGGAATGTTATCTTAAGCTTAATGGTTC
GTTGTAG

Upstream 100 bases:

>100_bases
GAATTCTGAGTTTGTTTCCAAAAATTTGGAGCGCGGGGCATCTGCGCCCCGCGTTTTCTTGATTGTTAATTATGATATTT
GGTGGCATCGGAGGTGCAAA

Downstream 100 bases:

>100_bases
TAGCATATATCTTTAAGAGTTTTAGCAGTTGTGTAAACGTTATACGTGAAGTTTTTCGGTTAATTAAGTTTATTAACCGC
GTTTTCGCAACAGAATCTTA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MIGKLTLIVGPMYSGKTSELLSLVEIYSLGKKKYLVFKPEIDTRYSVDHVVSHTGQKVPAITIPSASKLLEKFDDINEKL
DAIFIDEVHFFDIDIIDVIKKIILKGVDVFCVGLDMSYKHRPFQTTASLMAIADEVIKKKAVCHVCGEYKAVVSHKTVNN
SGSEIDVGGMEKYIAVCRECYLKLNGSL

Sequences:

>Translated_188_residues
MIGKLTLIVGPMYSGKTSELLSLVEIYSLGKKKYLVFKPEIDTRYSVDHVVSHTGQKVPAITIPSASKLLEKFDDINEKL
DAIFIDEVHFFDIDIIDVIKKIILKGVDVFCVGLDMSYKHRPFQTTASLMAIADEVIKKKAVCHVCGEYKAVVSHKTVNN
SGSEIDVGGMEKYIAVCRECYLKLNGSL
>Mature_188_residues
MIGKLTLIVGPMYSGKTSELLSLVEIYSLGKKKYLVFKPEIDTRYSVDHVVSHTGQKVPAITIPSASKLLEKFDDINEKL
DAIFIDEVHFFDIDIIDVIKKIILKGVDVFCVGLDMSYKHRPFQTTASLMAIADEVIKKKAVCHVCGEYKAVVSHKTVNN
SGSEIDVGGMEKYIAVCRECYLKLNGSL

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=183, Percent_Identity=31.6939890710383, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=25.2631578947368, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17543396, Length=183, Percent_Identity=32.7868852459016, Blast_Score=100, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 20919; Mature: 20919

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLTLIVGPMYSGKTSELLSLVEIYSLGKKKYLVFKPEIDTRYSVDHVVSHTGQKVPA
CCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCE
ITIPSASKLLEKFDDINEKLDAIFIDEVHFFDIDIIDVIKKIILKGVDVFCVGLDMSYKH
EECCCHHHHHHHHHHHHHHHHEEEECCEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCC
RPFQTTASLMAIADEVIKKKAVCHVCGEYKAVVSHKTVNNSGSEIDVGGMEKYIAVCREC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCEEECCHHHHHHHHHHHH
YLKLNGSL
HHHCCCCC
>Mature Secondary Structure
MIGKLTLIVGPMYSGKTSELLSLVEIYSLGKKKYLVFKPEIDTRYSVDHVVSHTGQKVPA
CCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCE
ITIPSASKLLEKFDDINEKLDAIFIDEVHFFDIDIIDVIKKIILKGVDVFCVGLDMSYKH
EECCCHHHHHHHHHHHHHHHHEEEECCEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCC
RPFQTTASLMAIADEVIKKKAVCHVCGEYKAVVSHKTVNNSGSEIDVGGMEKYIAVCREC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCEEECCHHHHHHHHHHHH
YLKLNGSL
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA