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The map label for this gene is infC [H]

Identifier: 239617823

GI number: 239617823

Start: 1548564

End: 1549118

Strand: Direct

Name: infC [H]

Synonym: Kole_1449

Alternate gene names: 239617823

Gene position: 1548564-1549118 (Clockwise)

Preceding gene: 239617822

Following gene: 239617824

Centisome position: 67.27

GC content: 42.34

Gene sequence:

>555_bases
ATGGATATCGGTAGCAAAAAGGGTTCTTCATATGCCCCGAGAAACAGTGAGATAAGAGTTGCAAAGGTCAGGGTAATCGA
TGAAAATGGTCAACAACTAGGAATAATGCCAACTCCACAGGCACTCGACGTTGCGAGAGAAAAAGGCTTGGATCTTGTTC
TGGTATCGCCAAATGCGAATCCGCCTGTAGCCAGAATAATGGATTATGGGAAGTACAAGTACGAAAAGGAAAAGCGTGCC
AAGGAAGCAAAGAAAAAAGCAAAGCAGGTTCAGCTCAAGCAGATGAAATTCCGTTTGCGTATTGAAGACCATGATTTTCA
CACAAAGGTTAACAGAATAAGGCAATTTCTCTCCAAGGGTAACAAAGTGCGAGTGGTGATTATGTTCAGGGGAAGAGAAA
TGGCTTTCACAGATCAAGGTAAACAGCTTCTTGATAGAGTAGCTGAAGAACTCAAGGAGATAGCAGAGATCGATAAAAGT
GCGAAGCTTGAAGGAAGAGATATGTGGATGATTTTAAGACCAAAATCACCTCAAGGAGGTAAGTCTGATGGCTAA

Upstream 100 bases:

>100_bases
AAGAGGAGCTGTGCTCCCACCCCCGCCAGAAAAGCCAAGGGGTCAATACTCGGTTTCAGTACCAGGCGGGTGTTTTGCCG
CCTGTTTTTTTTGAGAGGTG

Downstream 100 bases:

>100_bases
GACGAAAATGAAGACACACAAGGCAACTGCTAAACGTTTTAAGATAACCGGTAGCGGCAAGGTAATGCGCCAGCACTCCG
GGAAAAACCATAATACTGGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MDIGSKKGSSYAPRNSEIRVAKVRVIDENGQQLGIMPTPQALDVAREKGLDLVLVSPNANPPVARIMDYGKYKYEKEKRA
KEAKKKAKQVQLKQMKFRLRIEDHDFHTKVNRIRQFLSKGNKVRVVIMFRGREMAFTDQGKQLLDRVAEELKEIAEIDKS
AKLEGRDMWMILRPKSPQGGKSDG

Sequences:

>Translated_184_residues
MDIGSKKGSSYAPRNSEIRVAKVRVIDENGQQLGIMPTPQALDVAREKGLDLVLVSPNANPPVARIMDYGKYKYEKEKRA
KEAKKKAKQVQLKQMKFRLRIEDHDFHTKVNRIRQFLSKGNKVRVVIMFRGREMAFTDQGKQLLDRVAEELKEIAEIDKS
AKLEGRDMWMILRPKSPQGGKSDG
>Mature_184_residues
MDIGSKKGSSYAPRNSEIRVAKVRVIDENGQQLGIMPTPQALDVAREKGLDLVLVSPNANPPVARIMDYGKYKYEKEKRA
KEAKKKAKQVQLKQMKFRLRIEDHDFHTKVNRIRQFLSKGNKVRVVIMFRGREMAFTDQGKQLLDRVAEELKEIAEIDKS
AKLEGRDMWMILRPKSPQGGKSDG

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=178, Percent_Identity=45.5056179775281, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21052; Mature: 21052

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIGSKKGSSYAPRNSEIRVAKVRVIDENGQQLGIMPTPQALDVAREKGLDLVLVSPNAN
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCCCHHHHHHHHCCCEEEEECCCCC
PPVARIMDYGKYKYEKEKRAKEAKKKAKQVQLKQMKFRLRIEDHDFHTKVNRIRQFLSKG
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCC
NKVRVVIMFRGREMAFTDQGKQLLDRVAEELKEIAEIDKSAKLEGRDMWMILRPKSPQGG
CEEEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC
KSDG
CCCC
>Mature Secondary Structure
MDIGSKKGSSYAPRNSEIRVAKVRVIDENGQQLGIMPTPQALDVAREKGLDLVLVSPNAN
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCCCHHHHHHHHCCCEEEEECCCCC
PPVARIMDYGKYKYEKEKRAKEAKKKAKQVQLKQMKFRLRIEDHDFHTKVNRIRQFLSKG
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCC
NKVRVVIMFRGREMAFTDQGKQLLDRVAEELKEIAEIDKSAKLEGRDMWMILRPKSPQGG
CEEEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC
KSDG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]