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The map label for this gene is nth [C]

Identifier: 239617764

GI number: 239617764

Start: 1476284

End: 1476922

Strand: Direct

Name: nth [C]

Synonym: Kole_1389

Alternate gene names: 239617764

Gene position: 1476284-1476922 (Clockwise)

Preceding gene: 239617763

Following gene: 239617771

Centisome position: 64.13

GC content: 42.25

Gene sequence:

>639_bases
ATGGGAAATCGACTTGAGGAGATTTACTGCCTCCTTTATGATGTTTATGGCCCGCAGGGTTGGTGGCCTGCGGATACTCA
GTTTGAAGTGATAGTGGGAGCAGTGCTGACGCAGAATGTAGCGTGGAAGAATGTGGAACGTGCAATTGAAAATTTGAAGA
ACGCTGATGCTTTAGAGCCTGAGAAATTAATCGGGTTAGAAAAGGAGAAACTTGCCCTTTTGATAAAACCAACCGGTTTT
TATAATGCCAAAAGCGAAACGCTTTTGAGAGTAACAAAGGCGTATCTTTCTGAGCGTTGGGAAGATCTATCCACGAAAGA
ACTGCGAAAGAGGCTTCTCAAGATAAAGGGAATCGGTAAGGAAACTGCCGACTCGATTATTCTTTATGCTTTCGATAGGG
CGATATTCGTTGTGGACAAATACACCGTACGTTTCGTCACTCGACTGGGTATAACCACTCATGAGACGTATGATGAAGTT
CAAAGAATCTTTCATGAACAGCTTAAACCCGATGTTGAGCTTTATAAGGAATATCACGCTCTTATAGTGGAACATGCAAA
AAAATACTGTAAAAAACAGCCGGACTGTGCCGGCTGCTTTATAGGTGACTGTAAATTCAGAAAGGAATCTCAGATATGA

Upstream 100 bases:

>100_bases
ATTGTGAAAGCCTTCGAAGCAGGAGAAACCATTGATGTGAGAGAACTAAAACCATATTACCTTCAAAAATCTGTTGCTGA
ATTGAACTGGGAGAGAAAGC

Downstream 100 bases:

>100_bases
ATGGGATTTCCCTCAAGACCCTCCGCTGCATCACGAATAATTTCTGACAGGGTTGGATGGGGGTGAATGGATTTCAGTAA
TTCTTCTACCGTGAGCTGTT

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MGNRLEEIYCLLYDVYGPQGWWPADTQFEVIVGAVLTQNVAWKNVERAIENLKNADALEPEKLIGLEKEKLALLIKPTGF
YNAKSETLLRVTKAYLSERWEDLSTKELRKRLLKIKGIGKETADSIILYAFDRAIFVVDKYTVRFVTRLGITTHETYDEV
QRIFHEQLKPDVELYKEYHALIVEHAKKYCKKQPDCAGCFIGDCKFRKESQI

Sequences:

>Translated_212_residues
MGNRLEEIYCLLYDVYGPQGWWPADTQFEVIVGAVLTQNVAWKNVERAIENLKNADALEPEKLIGLEKEKLALLIKPTGF
YNAKSETLLRVTKAYLSERWEDLSTKELRKRLLKIKGIGKETADSIILYAFDRAIFVVDKYTVRFVTRLGITTHETYDEV
QRIFHEQLKPDVELYKEYHALIVEHAKKYCKKQPDCAGCFIGDCKFRKESQI
>Mature_211_residues
GNRLEEIYCLLYDVYGPQGWWPADTQFEVIVGAVLTQNVAWKNVERAIENLKNADALEPEKLIGLEKEKLALLIKPTGFY
NAKSETLLRVTKAYLSERWEDLSTKELRKRLLKIKGIGKETADSIILYAFDRAIFVVDKYTVRFVTRLGITTHETYDEVQ
RIFHEQLKPDVELYKEYHALIVEHAKKYCKKQPDCAGCFIGDCKFRKESQI

Specific function: Has Both An Apurinic And/Or Apyrimidinic Endonuclease Activity And A DNA N-Glycosylase Activity. Incises Damaged DNA At Cytosines, Thymines And Guanines. Acts On A Damaged Strand, 5' From The Damaged Site. Required For The Repair Of Both Oxidative DNA Da

COG id: COG2231

COG function: function code L; Uncharacterized protein related to Endonuclease III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Nth/MutY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 4.2.99.18

Molecular weight: Translated: 24641; Mature: 24510

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRLEEIYCLLYDVYGPQGWWPADTQFEVIVGAVLTQNVAWKNVERAIENLKNADALEP
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCH
EKLIGLEKEKLALLIKPTGFYNAKSETLLRVTKAYLSERWEDLSTKELRKRLLKIKGIGK
HHHHCCCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
ETADSIILYAFDRAIFVVDKYTVRFVTRLGITTHETYDEVQRIFHEQLKPDVELYKEYHA
HHHHHEEEEEECCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LIVEHAKKYCKKQPDCAGCFIGDCKFRKESQI
HHHHHHHHHHHCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
GNRLEEIYCLLYDVYGPQGWWPADTQFEVIVGAVLTQNVAWKNVERAIENLKNADALEP
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCH
EKLIGLEKEKLALLIKPTGFYNAKSETLLRVTKAYLSERWEDLSTKELRKRLLKIKGIGK
HHHHCCCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
ETADSIILYAFDRAIFVVDKYTVRFVTRLGITTHETYDEVQRIFHEQLKPDVELYKEYHA
HHHHHEEEEEECCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LIVEHAKKYCKKQPDCAGCFIGDCKFRKESQI
HHHHHHHHHHHCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyase [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]