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The map label for this gene is murG [H]

Identifier: 239617753

GI number: 239617753

Start: 1464564

End: 1465637

Strand: Reverse

Name: murG [H]

Synonym: Kole_1378

Alternate gene names: 239617753

Gene position: 1465637-1464564 (Counterclockwise)

Preceding gene: 239617754

Following gene: 239617752

Centisome position: 63.66

GC content: 42.18

Gene sequence:

>1074_bases
ATGCGTAAAAACCTTAAAGTAGCATTCTGCGGTGGCGGAACGGGCGGCCACTACTATCCTGCCATCGCCGTGTACCAGGA
ACTCTCAAAAAGGTTCGACATCGAAGCGTTGTATTTCACCATAGCCGGGAGGCTTGATGATAAAAACGTAGAACAGGACA
TACCACGAGTAAAAAGAATTCCTCTCAAAGTGAAGGGATTGCGAAGGCCCCTGGCCCATCCTGAGAATTTTTTCCGGGTT
TTGTCACATCTTCGCACCTCTTCAAAAGTAAAAAAAATCCTGAAAGATTTCAATCCTGATCTCGTTTTTTCGACGGGAGG
GTACATTTCATATCCCGTTGTTAAAGCTGCACACACGCTTGGAATCCCCATCTACATTCACGAACAAAATTCCATTCCAG
GGATTGCCAACAAAAAACTTTCTGTCTTCGCACGAAAAGTATTCGTTTCCTTTTCAGAAAGTGCGGATTATTTCCCTGTA
CCAAAAGATAAAATAATCGTAAGCGGAAACCCTGTCAGAAAACCCGTTAAAAATCGCGAAGAACTTCTCAATCAACTAGG
GTTCGACCCAAAAACTCCCTTTGTGGTCATAACCGGGGGAAGCCTTGGATCGGATTTGCTGAATAAATTGGCACTTTCGC
TTTACTCAAAGATACTTGAACACGGCCCTAACATAAATTTCCTTCACATTACTGGAAATGAAAATATCTCTGCTAAACTG
AATGAATTCCCCTTTGTTATTGAGAAAGCTTATGAACCAGAACTTCACGAATACATAAATATAGCTGATGCAGTTATAGC
GCGTGGTGGCGCAACAACGATAGCCGAAATCCTTAATTACAAGAGCTTTGGTATAATAATACCGTGGGAAGGCGCCGCAG
AAAATCATCAATATTACAACGCTGTTTCACTGGAAAAACAGGGGCAGGGTTGTGTTATACTTGAAAGCGCAGCAACTCCA
GAAAAAATTTATTCCACACTCGTTACAACCCTAAAAAGGATGAGCTTCAAAAACAATGAGGTTTTCAGAAATCCCGCAAG
GGTTATAGTAGAACATGTAGTTCGGGAGGAATAG

Upstream 100 bases:

>100_bases
GTAACATTGCCTTTTGTCAGTTACGGGGGTTCATCTTTGATATCCCTGCTTATAGGCTTTGCTTTCGTTTTCAGCATCAT
TTTAGAAAAGGAAGAAGATC

Downstream 100 bases:

>100_bases
AAGTTGAAATATCATTTTATTGGTATTGGCGGGATCGGAATGAGTGGTCTCGCTCTTCATTTAGCGGCTGAGGGTAATGA
GGTTTATGGCTCAAATTTCG

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRKNLKVAFCGGGTGGHYYPAIAVYQELSKRFDIEALYFTIAGRLDDKNVEQDIPRVKRIPLKVKGLRRPLAHPENFFRV
LSHLRTSSKVKKILKDFNPDLVFSTGGYISYPVVKAAHTLGIPIYIHEQNSIPGIANKKLSVFARKVFVSFSESADYFPV
PKDKIIVSGNPVRKPVKNREELLNQLGFDPKTPFVVITGGSLGSDLLNKLALSLYSKILEHGPNINFLHITGNENISAKL
NEFPFVIEKAYEPELHEYINIADAVIARGGATTIAEILNYKSFGIIIPWEGAAENHQYYNAVSLEKQGQGCVILESAATP
EKIYSTLVTTLKRMSFKNNEVFRNPARVIVEHVVREE

Sequences:

>Translated_357_residues
MRKNLKVAFCGGGTGGHYYPAIAVYQELSKRFDIEALYFTIAGRLDDKNVEQDIPRVKRIPLKVKGLRRPLAHPENFFRV
LSHLRTSSKVKKILKDFNPDLVFSTGGYISYPVVKAAHTLGIPIYIHEQNSIPGIANKKLSVFARKVFVSFSESADYFPV
PKDKIIVSGNPVRKPVKNREELLNQLGFDPKTPFVVITGGSLGSDLLNKLALSLYSKILEHGPNINFLHITGNENISAKL
NEFPFVIEKAYEPELHEYINIADAVIARGGATTIAEILNYKSFGIIIPWEGAAENHQYYNAVSLEKQGQGCVILESAATP
EKIYSTLVTTLKRMSFKNNEVFRNPARVIVEHVVREE
>Mature_357_residues
MRKNLKVAFCGGGTGGHYYPAIAVYQELSKRFDIEALYFTIAGRLDDKNVEQDIPRVKRIPLKVKGLRRPLAHPENFFRV
LSHLRTSSKVKKILKDFNPDLVFSTGGYISYPVVKAAHTLGIPIYIHEQNSIPGIANKKLSVFARKVFVSFSESADYFPV
PKDKIIVSGNPVRKPVKNREELLNQLGFDPKTPFVVITGGSLGSDLLNKLALSLYSKILEHGPNINFLHITGNENISAKL
NEFPFVIEKAYEPELHEYINIADAVIARGGATTIAEILNYKSFGIIIPWEGAAENHQYYNAVSLEKQGQGCVILESAATP
EKIYSTLVTTLKRMSFKNNEVFRNPARVIVEHVVREE

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=340, Percent_Identity=29.1176470588235, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39970; Mature: 39970

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLKVAFCGGGTGGHYYPAIAVYQELSKRFDIEALYFTIAGRLDDKNVEQDIPRVKRI
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHCHHHHCC
PLKVKGLRRPLAHPENFFRVLSHLRTSSKVKKILKDFNPDLVFSTGGYISYPVVKAAHTL
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECHHHHHHHHH
GIPIYIHEQNSIPGIANKKLSVFARKVFVSFSESADYFPVPKDKIIVSGNPVRKPVKNRE
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHH
ELLNQLGFDPKTPFVVITGGSLGSDLLNKLALSLYSKILEHGPNINFLHITGNENISAKL
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEC
NEFPFVIEKAYEPELHEYINIADAVIARGGATTIAEILNYKSFGIIIPWEGAAENHQYYN
CCCCCHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEE
AVSLEKQGQGCVILESAATPEKIYSTLVTTLKRMSFKNNEVFRNPARVIVEHVVREE
EEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRKNLKVAFCGGGTGGHYYPAIAVYQELSKRFDIEALYFTIAGRLDDKNVEQDIPRVKRI
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHCHHHHCC
PLKVKGLRRPLAHPENFFRVLSHLRTSSKVKKILKDFNPDLVFSTGGYISYPVVKAAHTL
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECHHHHHHHHH
GIPIYIHEQNSIPGIANKKLSVFARKVFVSFSESADYFPVPKDKIIVSGNPVRKPVKNRE
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHH
ELLNQLGFDPKTPFVVITGGSLGSDLLNKLALSLYSKILEHGPNINFLHITGNENISAKL
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEC
NEFPFVIEKAYEPELHEYINIADAVIARGGATTIAEILNYKSFGIIIPWEGAAENHQYYN
CCCCCHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEE
AVSLEKQGQGCVILESAATPEKIYSTLVTTLKRMSFKNNEVFRNPARVIVEHVVREE
EEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]