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The map label for this gene is glmU [H]

Identifier: 239617741

GI number: 239617741

Start: 1451291

End: 1452013

Strand: Direct

Name: glmU [H]

Synonym: Kole_1365

Alternate gene names: 239617741

Gene position: 1451291-1452013 (Clockwise)

Preceding gene: 239617740

Following gene: 239617749

Centisome position: 63.04

GC content: 40.39

Gene sequence:

>723_bases
ATGATCGAGTATCTCGTAATTCTCGCCGCCGGGAAAGGGACCCGCTTAAAGGCATCGACTTCAAAACCCCTTGTGAAAAT
CAACGATAAGAGTTTGATTGAATATGTTATTGGTAACGCAAAGGAGTTCGTGGACAGGATTTATATAGTTGCCGGTAACC
ACAATAAAGATGAATTAAGAGAGCACCTGGGAGATGGGTATGAATACTGTCTTCAGAAGGAACAGCTTGGAACTGCCCAT
GCCTTTAAGTGCGCGCTTAACAGCATAAAGAGCGATTCTGGAAATGTCATGCTTTTGTATGCTGATACGCCTTTAATAAA
TAAAGAAACGATAAAGAACATCGCCGATGTTCACCTGGTTCAAAAAAATGACATTACCTTTCTCACTGCTGAAACGAATA
CCTGGTTCCCGTACGCGAGTGTGTTGAGAGACGAGAGAGGGAACTTAATAAAAATAGACGAGACTTATGATTCGTCAAAA
TTGAAAACAAAAGAATATGCGATAGGCGCATACGTTTTCGGTTTGAGGTATGCGAAGAAGTATTCAGAAAATTTGCACCT
TTATGGCAGGAAGGAATTTTATATAGATCAGGTAATAAATGAAGCCATAAAAAATGGTGACAAAGTGGGTGCCTATAAGA
TTAAAGACGATACCCAGATAAGAGGAATAAACACCCCTGAAGATCTTGAATTTGCTAGAAGGCTGTTGGGCAAAGCAGAC
TGA

Upstream 100 bases:

>100_bases
TCAGGAACTGAACCTGTGCTTAGAATAACCTGTGAAATGAATTCGGAAGATGAAGCAGCGAATGTGATAGAACGTATTAT
TTCTGTCATGAGGTGATTTG

Downstream 100 bases:

>100_bases
TAGTCATTGATCCTTGAATAAAAAAGGGAGCTATCGTGAATGACAGATAACTCCCTTTCTTATTTTTGAGGGAAATTATT
CGAGTACTACCATCACCTGT

Product: Glucosamine-1-phosphate N-acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MIEYLVILAAGKGTRLKASTSKPLVKINDKSLIEYVIGNAKEFVDRIYIVAGNHNKDELREHLGDGYEYCLQKEQLGTAH
AFKCALNSIKSDSGNVMLLYADTPLINKETIKNIADVHLVQKNDITFLTAETNTWFPYASVLRDERGNLIKIDETYDSSK
LKTKEYAIGAYVFGLRYAKKYSENLHLYGRKEFYIDQVINEAIKNGDKVGAYKIKDDTQIRGINTPEDLEFARRLLGKAD

Sequences:

>Translated_240_residues
MIEYLVILAAGKGTRLKASTSKPLVKINDKSLIEYVIGNAKEFVDRIYIVAGNHNKDELREHLGDGYEYCLQKEQLGTAH
AFKCALNSIKSDSGNVMLLYADTPLINKETIKNIADVHLVQKNDITFLTAETNTWFPYASVLRDERGNLIKIDETYDSSK
LKTKEYAIGAYVFGLRYAKKYSENLHLYGRKEFYIDQVINEAIKNGDKVGAYKIKDDTQIRGINTPEDLEFARRLLGKAD
>Mature_240_residues
MIEYLVILAAGKGTRLKASTSKPLVKINDKSLIEYVIGNAKEFVDRIYIVAGNHNKDELREHLGDGYEYCLQKEQLGTAH
AFKCALNSIKSDSGNVMLLYADTPLINKETIKNIADVHLVQKNDITFLTAETNTWFPYASVLRDERGNLIKIDETYDSSK
LKTKEYAIGAYVFGLRYAKKYSENLHLYGRKEFYIDQVINEAIKNGDKVGAYKIKDDTQIRGINTPEDLEFARRLLGKAD

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=236, Percent_Identity=29.2372881355932, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 27225; Mature: 27225

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYLVILAAGKGTRLKASTSKPLVKINDKSLIEYVIGNAKEFVDRIYIVAGNHNKDELR
CCEEEEEEECCCCCEEEECCCCCEEEECCHHHHHHHHCCHHHHHHEEEEEECCCCHHHHH
EHLGDGYEYCLQKEQLGTAHAFKCALNSIKSDSGNVMLLYADTPLINKETIKNIADVHLV
HHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHEEEE
QKNDITFLTAETNTWFPYASVLRDERGNLIKIDETYDSSKLKTKEYAIGAYVFGLRYAKK
ECCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
YSENLHLYGRKEFYIDQVINEAIKNGDKVGAYKIKDDTQIRGINTPEDLEFARRLLGKAD
HCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MIEYLVILAAGKGTRLKASTSKPLVKINDKSLIEYVIGNAKEFVDRIYIVAGNHNKDELR
CCEEEEEEECCCCCEEEECCCCCEEEECCHHHHHHHHCCHHHHHHEEEEEECCCCHHHHH
EHLGDGYEYCLQKEQLGTAHAFKCALNSIKSDSGNVMLLYADTPLINKETIKNIADVHLV
HHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHEEEE
QKNDITFLTAETNTWFPYASVLRDERGNLIKIDETYDSSKLKTKEYAIGAYVFGLRYAKK
ECCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
YSENLHLYGRKEFYIDQVINEAIKNGDKVGAYKIKDDTQIRGINTPEDLEFARRLLGKAD
HCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA