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The map label for this gene is malA [H]

Identifier: 239617615

GI number: 239617615

Start: 1314725

End: 1315855

Strand: Direct

Name: malA [H]

Synonym: Kole_1236

Alternate gene names: 239617615

Gene position: 1314725-1315855 (Clockwise)

Preceding gene: 239617614

Following gene: 239617616

Centisome position: 57.11

GC content: 38.11

Gene sequence:

>1131_bases
TTGTTTATCTGGGATTTTATCTTTGAAGCACTTACATATTCCAGCTTTGCTGCAAGAAGCATGCTTGGCCAATTCTTTGA
TATCGCGGGTTTCAGTCCCGTGGAGATTGGCTATTTGGTGGCTATGCTACCCCTTGTAGCATTGATTTCAAATCCATTCT
GGTTTAGAGTGGGATCAAGGATTACGGATAAAAAAGCCTTCATAATTGTTTCGCTCATTTCGGGCTTTTTATTCTGGCCA
ATATACATTTCGAGAAATTTCATTCTTGGCCTCATTTCAATTGCCGCCTTTTCCTTTTTCTTCTCGGCCGTTGTCCCCCT
TGGTGATTCACTTATGATGGCTTCCATAAAAAAGCACGGTGGCACTTTCGATAAAATCAGACTCTTCGGTACCATAGGTT
TTTCTATTACAGCACTGCTTTTGAGTTATCTGGTTAAATGGGGTTTCATCTGGTATTTTATAGTTGCTTCAATCAGCCTT
TTTATCGCTCCCATTGTGATAAATATAAAAAGAAAGAATAACAAGAAAATACAGGAAAAGCCAAAAACAGTGTTTATAAG
AAACGGAAATCTGTTTACTTTTGTTCTTATGACTGTTGGAATGATCTTCGGTGTAACTCTAGGAAGTTTTCATAACACCT
TTTTTCCTGTTTTATCTCGAGAAATGGGCTATGATAAATCGGTTGTAGGACTTGTCTTTTCTTTCATGGCGATTACAGAG
ATTCCTTTCCTGTTTTTCGCAGAAAAGATCATAAGAAAGTTTGGAAATTTCAGTGTTCTTGTAGTCGGCATGCTGGTAAG
TGCTTTGAGAGTTGTGCTGGTTACTTATGTCTCGGGACTGGTGCCTTTGTTGCTAACCCAGGCTCTTCACGGGCTCACGT
ACATCTTGATGTATTACGCTCTTTTTAACTATATACATTTCAGATTACCCGAGAAATACTTGACCAATGCTCAAAGCCTT
TTCTGGCTAACAAGTTCAGGATTGACATATATTTTTGGGTCAATTATCGGTGGTTATCTCATAGAGTACTTTCAAACAGT
AACGGGTTTTAGGATTATGGGTTATTCAGGTTTTATAGTAACCGGAGCAATCATAGCAATTTTCCTTATATTTAAACGCA
AGACATCATAA

Upstream 100 bases:

>100_bases
TCCTTCCTACCCGATCACGTTACGTAGAGATGGGTCATGGTACTTCCAGCCACATGGGTCTATAATCTTTATTAAACGTA
CATTTTTAGGGGAGTTTGAT

Downstream 100 bases:

>100_bases
CTTTCAGCGCTTTCATTTAAGTGAGCGTCAAAGAAGAAAACAGGGACTGTGTCGTAGGGGACTGTACCTGTTTTTCGAGG
CTCACTCACACGTAGCGTGC

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MFIWDFIFEALTYSSFAARSMLGQFFDIAGFSPVEIGYLVAMLPLVALISNPFWFRVGSRITDKKAFIIVSLISGFLFWP
IYISRNFILGLISIAAFSFFFSAVVPLGDSLMMASIKKHGGTFDKIRLFGTIGFSITALLLSYLVKWGFIWYFIVASISL
FIAPIVINIKRKNNKKIQEKPKTVFIRNGNLFTFVLMTVGMIFGVTLGSFHNTFFPVLSREMGYDKSVVGLVFSFMAITE
IPFLFFAEKIIRKFGNFSVLVVGMLVSALRVVLVTYVSGLVPLLLTQALHGLTYILMYYALFNYIHFRLPEKYLTNAQSL
FWLTSSGLTYIFGSIIGGYLIEYFQTVTGFRIMGYSGFIVTGAIIAIFLIFKRKTS

Sequences:

>Translated_376_residues
MFIWDFIFEALTYSSFAARSMLGQFFDIAGFSPVEIGYLVAMLPLVALISNPFWFRVGSRITDKKAFIIVSLISGFLFWP
IYISRNFILGLISIAAFSFFFSAVVPLGDSLMMASIKKHGGTFDKIRLFGTIGFSITALLLSYLVKWGFIWYFIVASISL
FIAPIVINIKRKNNKKIQEKPKTVFIRNGNLFTFVLMTVGMIFGVTLGSFHNTFFPVLSREMGYDKSVVGLVFSFMAITE
IPFLFFAEKIIRKFGNFSVLVVGMLVSALRVVLVTYVSGLVPLLLTQALHGLTYILMYYALFNYIHFRLPEKYLTNAQSL
FWLTSSGLTYIFGSIIGGYLIEYFQTVTGFRIMGYSGFIVTGAIIAIFLIFKRKTS
>Mature_376_residues
MFIWDFIFEALTYSSFAARSMLGQFFDIAGFSPVEIGYLVAMLPLVALISNPFWFRVGSRITDKKAFIIVSLISGFLFWP
IYISRNFILGLISIAAFSFFFSAVVPLGDSLMMASIKKHGGTFDKIRLFGTIGFSITALLLSYLVKWGFIWYFIVASISL
FIAPIVINIKRKNNKKIQEKPKTVFIRNGNLFTFVLMTVGMIFGVTLGSFHNTFFPVLSREMGYDKSVVGLVFSFMAITE
IPFLFFAEKIIRKFGNFSVLVVGMLVSALRVVLVTYVSGLVPLLLTQALHGLTYILMYYALFNYIHFRLPEKYLTNAQSL
FWLTSSGLTYIFGSIIGGYLIEYFQTVTGFRIMGYSGFIVTGAIIAIFLIFKRKTS

Specific function: High affinity transport of maltose [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=258, Percent_Identity=22.8682170542636, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24580953, Length=273, Percent_Identity=25.2747252747253, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004750 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42482; Mature: 42482

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8190087 [H]