Click here to switch to the map view.

The map label for this gene is nanE [H]

Identifier: 239617565

GI number: 239617565

Start: 1255993

End: 1256712

Strand: Reverse

Name: nanE [H]

Synonym: Kole_1183

Alternate gene names: 239617565

Gene position: 1256712-1255993 (Counterclockwise)

Preceding gene: 239617579

Following gene: 239617564

Centisome position: 54.59

GC content: 41.53

Gene sequence:

>720_bases
TTGAAGACAGAATTACTTGAAAAATTAAAAAGTGGATTGATAGTTTCATGCCAGGCCTTTGAAGGTGAACCTCTTTACGG
GGATGGCATCATGGTTCGAATGGCCAACGCCGCTGTAATAGGCGGAGCAAAGGCCATAAGAACGAATGGAGTTAAAGACA
TTAAACAAATAAAAGAAGCTCTGGATGTCCCTGTAATAGGGATTATAAAGAAACATATAGAGGGTTATTCGGTTTACATT
ACCCCCACTTCCAAAGAAGCACTCGAGGTCCTTGAAGCAGGCGCTGATATAGTAGCCCTTGACTGCACAAAAAGGCCGAG
GCCTGAGCCCTTAAAGGATATTTTCGAAAATATAAGAAGTAATTATCCAAACGCGTTGATCATGGCTGACATAGCAACTG
TCGAAGATGCTGAATTTGTAAGCCAATTATCACCGGATTTTCTTGCCACAACACTATCTGGTTATACCAAGGAAACGCGT
AATAGGCCTAAACCTGATATTGAGTTAGTCAAGATTCTGGCAGAACGATTCAGTATCCCTGTTATAGCTGAAGGTAATTA
TTGGGAACCCTCACAGGTGTTAGAGGCAATGAAAGCCGGAGCTTTTGCCGTTACCATTGGCAGCGCTATAACCCGACCAC
ATTTGGTTACTGCTAGATTCAATAAATTTATTCAGAATTGGACTAAGAATAAGGGATTGTCGGAGGTTCAAAGAAAATGA

Upstream 100 bases:

>100_bases
CGGTGCTAATACATCGTGAGATGTTCTCAAAAATTATTTATCATTTTGGAGAAAATCTCCATTCGTAGTATTATTAGCTC
GATAAGTCGAGGTGATTCGT

Downstream 100 bases:

>100_bases
AGTTAGAAAGAGATGTTGTAATTGTCGGTGGAGGAATCGCCGGCGTACATGCAGCGATAGCATGTGGAAGAGCTGGTTTG
AAAACGACATTAATTGAGCA

Product: N-acylglucosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKTELLEKLKSGLIVSCQAFEGEPLYGDGIMVRMANAAVIGGAKAIRTNGVKDIKQIKEALDVPVIGIIKKHIEGYSVYI
TPTSKEALEVLEAGADIVALDCTKRPRPEPLKDIFENIRSNYPNALIMADIATVEDAEFVSQLSPDFLATTLSGYTKETR
NRPKPDIELVKILAERFSIPVIAEGNYWEPSQVLEAMKAGAFAVTIGSAITRPHLVTARFNKFIQNWTKNKGLSEVQRK

Sequences:

>Translated_239_residues
MKTELLEKLKSGLIVSCQAFEGEPLYGDGIMVRMANAAVIGGAKAIRTNGVKDIKQIKEALDVPVIGIIKKHIEGYSVYI
TPTSKEALEVLEAGADIVALDCTKRPRPEPLKDIFENIRSNYPNALIMADIATVEDAEFVSQLSPDFLATTLSGYTKETR
NRPKPDIELVKILAERFSIPVIAEGNYWEPSQVLEAMKAGAFAVTIGSAITRPHLVTARFNKFIQNWTKNKGLSEVQRK
>Mature_239_residues
MKTELLEKLKSGLIVSCQAFEGEPLYGDGIMVRMANAAVIGGAKAIRTNGVKDIKQIKEALDVPVIGIIKKHIEGYSVYI
TPTSKEALEVLEAGADIVALDCTKRPRPEPLKDIFENIRSNYPNALIMADIATVEDAEFVSQLSPDFLATTLSGYTKETR
NRPKPDIELVKILAERFSIPVIAEGNYWEPSQVLEAMKAGAFAVTIGSAITRPHLVTARFNKFIQNWTKNKGLSEVQRK

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=215, Percent_Identity=41.3953488372093, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 26331; Mature: 26331

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTELLEKLKSGLIVSCQAFEGEPLYGDGIMVRMANAAVIGGAKAIRTNGVKDIKQIKEA
CCHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECHHEECCCHHHHHCCHHHHHHHHHH
LDVPVIGIIKKHIEGYSVYITPTSKEALEVLEAGADIVALDCTKRPRPEPLKDIFENIRS
HCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
NYPNALIMADIATVEDAEFVSQLSPDFLATTLSGYTKETRNRPKPDIELVKILAERFSIP
CCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
VIAEGNYWEPSQVLEAMKAGAFAVTIGSAITRPHLVTARFNKFIQNWTKNKGLSEVQRK
EEECCCCCCHHHHHHHHHCCCEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MKTELLEKLKSGLIVSCQAFEGEPLYGDGIMVRMANAAVIGGAKAIRTNGVKDIKQIKEA
CCHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECHHEECCCHHHHHCCHHHHHHHHHH
LDVPVIGIIKKHIEGYSVYITPTSKEALEVLEAGADIVALDCTKRPRPEPLKDIFENIRS
HCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
NYPNALIMADIATVEDAEFVSQLSPDFLATTLSGYTKETRNRPKPDIELVKILAERFSIP
CCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
VIAEGNYWEPSQVLEAMKAGAFAVTIGSAITRPHLVTARFNKFIQNWTKNKGLSEVQRK
EEECCCCCCHHHHHHHHHCCCEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]