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The map label for this gene is crp [C]

Identifier: 239617539

GI number: 239617539

Start: 1225087

End: 1225761

Strand: Direct

Name: crp [C]

Synonym: Kole_1156

Alternate gene names: 239617539

Gene position: 1225087-1225761 (Clockwise)

Preceding gene: 239617536

Following gene: 239617540

Centisome position: 53.22

GC content: 37.04

Gene sequence:

>675_bases
ATGAATCCACTAATTCTAAACCTTGCACGTTCAAAGCTTTTTAAAGGATTAACCGTTGGAGAACTTGAAACAATTTTTCG
AGAAATTTTGTATCGTATCGAAAAGTACAAAGCCGGTGAATTTGTCCGTTTTCGTGGAGACAGTTGTGATGATCTCCTGA
TTCTTCTGGATGGTAAGGTTAAAACGGAGATGCAAGACTTTAATGGAAAAGTCGTCAGGATAGAAGTAATGGACGCACCA
AGCCTTTTAGCTTCAGGTTTCTTATTTGCCACCGATAATGTATTTCCCGTTGACGTTATCACGATTACTGATTGTTCATT
CCTGACAATACCGAAAAAATCAGTAATTAATCTTTGTAGAAAAAACGAAAAGTTTCTGTTGAATCTTCTGCAAGATATGG
GGGATAGATTGGTATTTCTCTCGGAAAAACTCTATATGCTGACGTTGAGAACCCTCAAAGAGAAGATAGCTGATTATATC
CTTTCGCTTTGCAAAGATAAACAATGTGAAGTATCTGTTCCTCTAACAAAAGAAGAGCTTTCACAGGTATTTGGGGTTGC
AAGGCCTTCGCTTTCACGTGCTTTTGCCGATCTTGCAAGAGATGGAATTTTAGAAATGGATGGAAGGAAGATAATCATAA
AGGATTTTGAAAAGTTAAAGGCCCTTATAAAATAA

Upstream 100 bases:

>100_bases
GCTCATATAAATTCCTCCTTTTTTAGTTGGTTTTTCTTTTCAATTCCAGTATAATTTTTTTGAATCATTCAATCGGTAAC
ATATGTTACGGAGGATAGAG

Downstream 100 bases:

>100_bases
GATTTTTAGCGAGGCATCATCGCAAATTAAAACTACGGCTGATGCGTTGTGCCCGGTGTGTAACAGTGCACCGGGCAAAT
TAATGCGGTATTATAGGAAG

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcription Regulator; Transcriptional Regulatory Protein; Transcription Regulator CRP Family; Crp Family Transcriptional Regulator; Transcriptional Regulator Crp Family; Regulatory Protein; Fnr-Like Transcriptional Activator; Catabolite Gene Activator; Crp/Fnr Family Transcriptional Regulator; CAMP-Bindin Transcriptional Regulator; CAMP-Regulatory Protein

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNPLILNLARSKLFKGLTVGELETIFREILYRIEKYKAGEFVRFRGDSCDDLLILLDGKVKTEMQDFNGKVVRIEVMDAP
SLLASGFLFATDNVFPVDVITITDCSFLTIPKKSVINLCRKNEKFLLNLLQDMGDRLVFLSEKLYMLTLRTLKEKIADYI
LSLCKDKQCEVSVPLTKEELSQVFGVARPSLSRAFADLARDGILEMDGRKIIIKDFEKLKALIK

Sequences:

>Translated_224_residues
MNPLILNLARSKLFKGLTVGELETIFREILYRIEKYKAGEFVRFRGDSCDDLLILLDGKVKTEMQDFNGKVVRIEVMDAP
SLLASGFLFATDNVFPVDVITITDCSFLTIPKKSVINLCRKNEKFLLNLLQDMGDRLVFLSEKLYMLTLRTLKEKIADYI
LSLCKDKQCEVSVPLTKEELSQVFGVARPSLSRAFADLARDGILEMDGRKIIIKDFEKLKALIK
>Mature_224_residues
MNPLILNLARSKLFKGLTVGELETIFREILYRIEKYKAGEFVRFRGDSCDDLLILLDGKVKTEMQDFNGKVVRIEVMDAP
SLLASGFLFATDNVFPVDVITITDCSFLTIPKKSVINLCRKNEKFLLNLLQDMGDRLVFLSEKLYMLTLRTLKEKIADYI
LSLCKDKQCEVSVPLTKEELSQVFGVARPSLSRAFADLARDGILEMDGRKIIIKDFEKLKALIK

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25509; Mature: 25509

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLILNLARSKLFKGLTVGELETIFREILYRIEKYKAGEFVRFRGDSCDDLLILLDGKV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCH
KTEMQDFNGKVVRIEVMDAPSLLASGFLFATDNVFPVDVITITDCSFLTIPKKSVINLCR
HHHHHHCCCCEEEEEEECCHHHHHCCCEEEECCCCEEEEEEECCCCEEECCHHHHHHHHH
KNEKFLLNLLQDMGDRLVFLSEKLYMLTLRTLKEKIADYILSLCKDKQCEVSVPLTKEEL
CCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHH
SQVFGVARPSLSRAFADLARDGILEMDGRKIIIKDFEKLKALIK
HHHHHCCCHHHHHHHHHHHHCCCEEECCCEEEHHHHHHHHHHHC
>Mature Secondary Structure
MNPLILNLARSKLFKGLTVGELETIFREILYRIEKYKAGEFVRFRGDSCDDLLILLDGKV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCH
KTEMQDFNGKVVRIEVMDAPSLLASGFLFATDNVFPVDVITITDCSFLTIPKKSVINLCR
HHHHHHCCCCEEEEEEECCHHHHHCCCEEEECCCCEEEEEEECCCCEEECCHHHHHHHHH
KNEKFLLNLLQDMGDRLVFLSEKLYMLTLRTLKEKIADYILSLCKDKQCEVSVPLTKEEL
CCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHH
SQVFGVARPSLSRAFADLARDGILEMDGRKIIIKDFEKLKALIK
HHHHHCCCHHHHHHHHHHHHCCCEEECCCEEEHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA