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The map label for this gene is ygbD [C]

Identifier: 239617507

GI number: 239617507

Start: 1191760

End: 1193106

Strand: Reverse

Name: ygbD [C]

Synonym: Kole_1123

Alternate gene names: 239617507

Gene position: 1193106-1191760 (Counterclockwise)

Preceding gene: 239617508

Following gene: 239617506

Centisome position: 51.83

GC content: 43.95

Gene sequence:

>1347_bases
ATGAAAAGGGACGTTATCATAATCGGTGGAGGCCCCGCCGGGCTTGTTACTGCAACAACAGCAAAGAAAACCTATCCAGA
CAAAGAAATCCTGATAATCAGAAAAGAAAAAGTCGGACTTGTTCCCTGCGGTATTCCGTACATTTTTGGTACCATAGGTT
CGGTTGACGGCAACATAATGGGAACCAAACCCGCAGAAAACCTCGGTGTGGAATTCATGACTGCGGAGGTTACCAGCGTA
GATTTCGAAGCCAAAATAGTTGAAACAGCGTCAGGTGAAAGCGTCCAGTATGACAAACTTGTTTTCGCTACTGGTTCCAT
ACCGGTTATCCCAAAAATAGAAGGAGCGGAATTAAGCGGTGTTTACGCAGTTCCAAAGAATAAAGAAGAGATAGAGAAGG
TTTATGAAGCGGCTAAGAAAGCGCATAATGTAATAATCATTGGCGGAGGATTCATCGGCGTCGAAGTTGGCGATGAAATC
AGAAAGATGGGAAAGAAAGTTACGATAATTGAAGCTAAGCCTCATCTCCTTCCTGCCGCTTTCGACGAATCTTTTGGCAA
GTTGATGGAAGAAAATCTTAAGGAAAAAAATGTCGTTGTGATGACCGAAACCCTTGTAACAAAGATTCTTGGAACAGATA
AGGTCGAAGGGGTTGAACTTTCCAGTGGTGAAAAACTCTCAACAGACATGGTCATTTTTGCTGTGGGGTACAAACCGAAT
ACTGAACTTGTGAAGAAGCTTCCTATCCATCTCGGATACAGTGGTTCCATCTGGGTGGATGAATACATGAGAACCAGCGT
TAAAGATGTTTTCGCTGTCGGAGATTGTGCGGAACACAAGGATTTCTTCACCAGAAAGCCAAGTAAACTCATGCTGGCAT
CTACAGCTGCATTTGACGCAAGAGTTGCTGGAGCGAATCTTTACACCCTTAAAGTTGTGAGAGAGAATCATGGAAATCTG
GGAGTATTCTCAACCTCGGTCGAAGGATTGACGCTTGGGGCTGCTGGAATGACATACAAAACGGCCTGCGAGGAAGGTTT
CGAATGTGTAGTTGGAGAGGCAAAAAGCATAGATAGGCATCCTGGTACACTTCCAGATAAAAGCAGCCTTTATGTAATGT
TGATCTTCTCAAAGGAGAGTGGAATACTGCTTGGTGCACAGATAGCTGGTGGAAAGAGTGTAGGCGAAATGATAAATATT
CTTGGACTTGGCTTACAAATGGGAGTTACGGCTAACGACCTGGTAACCATGCAGATAGGCACCCATCCACTTTTGACATC
TGCTCCCACTGTATATCCAATTATAACTGCAGCTGAAGCTGCTATAAGAAAACTTAGAGCTGAATAG

Upstream 100 bases:

>100_bases
GCGAACAATTCCTGAGAGAGTTCGAAAGCCTTGGTCACGTAAAAAAGATTGTCTACAATGGAACTGTATTCTACAGATTC
ATAAAGGAGGGATAACTTCG

Downstream 100 bases:

>100_bases
TAAGATGAACCCATGTATAATTGGGTTGGGATCCTTAGATTCCAACCCAGTTATTTTATACCCGGATAAACTTAGGGGTG
ATGTATATGCCTGGTTTTGG

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKRDVIIIGGGPAGLVTATTAKKTYPDKEILIIRKEKVGLVPCGIPYIFGTIGSVDGNIMGTKPAENLGVEFMTAEVTSV
DFEAKIVETASGESVQYDKLVFATGSIPVIPKIEGAELSGVYAVPKNKEEIEKVYEAAKKAHNVIIIGGGFIGVEVGDEI
RKMGKKVTIIEAKPHLLPAAFDESFGKLMEENLKEKNVVVMTETLVTKILGTDKVEGVELSSGEKLSTDMVIFAVGYKPN
TELVKKLPIHLGYSGSIWVDEYMRTSVKDVFAVGDCAEHKDFFTRKPSKLMLASTAAFDARVAGANLYTLKVVRENHGNL
GVFSTSVEGLTLGAAGMTYKTACEEGFECVVGEAKSIDRHPGTLPDKSSLYVMLIFSKESGILLGAQIAGGKSVGEMINI
LGLGLQMGVTANDLVTMQIGTHPLLTSAPTVYPIITAAEAAIRKLRAE

Sequences:

>Translated_448_residues
MKRDVIIIGGGPAGLVTATTAKKTYPDKEILIIRKEKVGLVPCGIPYIFGTIGSVDGNIMGTKPAENLGVEFMTAEVTSV
DFEAKIVETASGESVQYDKLVFATGSIPVIPKIEGAELSGVYAVPKNKEEIEKVYEAAKKAHNVIIIGGGFIGVEVGDEI
RKMGKKVTIIEAKPHLLPAAFDESFGKLMEENLKEKNVVVMTETLVTKILGTDKVEGVELSSGEKLSTDMVIFAVGYKPN
TELVKKLPIHLGYSGSIWVDEYMRTSVKDVFAVGDCAEHKDFFTRKPSKLMLASTAAFDARVAGANLYTLKVVRENHGNL
GVFSTSVEGLTLGAAGMTYKTACEEGFECVVGEAKSIDRHPGTLPDKSSLYVMLIFSKESGILLGAQIAGGKSVGEMINI
LGLGLQMGVTANDLVTMQIGTHPLLTSAPTVYPIITAAEAAIRKLRAE
>Mature_448_residues
MKRDVIIIGGGPAGLVTATTAKKTYPDKEILIIRKEKVGLVPCGIPYIFGTIGSVDGNIMGTKPAENLGVEFMTAEVTSV
DFEAKIVETASGESVQYDKLVFATGSIPVIPKIEGAELSGVYAVPKNKEEIEKVYEAAKKAHNVIIIGGGFIGVEVGDEI
RKMGKKVTIIEAKPHLLPAAFDESFGKLMEENLKEKNVVVMTETLVTKILGTDKVEGVELSSGEKLSTDMVIFAVGYKPN
TELVKKLPIHLGYSGSIWVDEYMRTSVKDVFAVGDCAEHKDFFTRKPSKLMLASTAAFDARVAGANLYTLKVVRENHGNL
GVFSTSVEGLTLGAAGMTYKTACEEGFECVVGEAKSIDRHPGTLPDKSSLYVMLIFSKESGILLGAQIAGGKSVGEMINI
LGLGLQMGVTANDLVTMQIGTHPLLTSAPTVYPIITAAEAAIRKLRAE

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=278, Percent_Identity=27.3381294964029, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI65787454, Length=278, Percent_Identity=27.3381294964029, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI21389617, Length=278, Percent_Identity=27.3381294964029, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI22202629, Length=252, Percent_Identity=25.3968253968254, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI4757732, Length=252, Percent_Identity=25.3968253968254, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789065, Length=209, Percent_Identity=31.1004784688995, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789765, Length=365, Percent_Identity=23.8356164383562, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786307, Length=348, Percent_Identity=25.8620689655172, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789915, Length=368, Percent_Identity=23.0978260869565, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788892, Length=188, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082354, Length=239, Percent_Identity=26.3598326359833, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=291, Percent_Identity=27.8350515463918, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32565766, Length=295, Percent_Identity=25.0847457627119, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24585130, Length=286, Percent_Identity=22.3776223776224, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639257, Length=327, Percent_Identity=23.5474006116208, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281359715, Length=327, Percent_Identity=23.5474006116208, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359713, Length=327, Percent_Identity=23.5474006116208, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639250, Length=327, Percent_Identity=23.5474006116208, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18543267, Length=327, Percent_Identity=23.5474006116208, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639252, Length=327, Percent_Identity=23.5474006116208, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47850; Mature: 47850

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDVIIIGGGPAGLVTATTAKKTYPDKEILIIRKEKVGLVPCGIPYIFGTIGSVDGNIM
CCCCEEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEECCCHHHHHHHCCCCCCEE
GTKPAENLGVEFMTAEVTSVDFEAKIVETASGESVQYDKLVFATGSIPVIPKIEGAELSG
CCCCCHHCCEEEEEEEEEEECEEEEEEECCCCCCEEECEEEEEECCCCEEECCCCCCCCE
VYAVPKNKEEIEKVYEAAKKAHNVIIIGGGFIGVEVGDEIRKMGKKVTIIEAKPHLLPAA
EEECCCCHHHHHHHHHHHHHHCCEEEEECCEEEEECCHHHHHCCCEEEEEECCCCCCCHH
FDESFGKLMEENLKEKNVVVMTETLVTKILGTDKVEGVELSSGEKLSTDMVIFAVGYKPN
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCEECCCCCEECCCEEEEEECCCCC
TELVKKLPIHLGYSGSIWVDEYMRTSVKDVFAVGDCAEHKDFFTRKPSKLMLASTAAFDA
HHHHHHCCEEECCCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCE
RVAGANLYTLKVVRENHGNLGVFSTSVEGLTLGAAGMTYKTACEEGFECVVGEAKSIDRH
EECCCEEEEEEEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHCCCEEEECCCCCCCCC
PGTLPDKSSLYVMLIFSKESGILLGAQIAGGKSVGEMINILGLGLQMGVTANDLVTMQIG
CCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCEEECCCCCCEEEEEEC
THPLLTSAPTVYPIITAAEAAIRKLRAE
CCCCCCCCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRDVIIIGGGPAGLVTATTAKKTYPDKEILIIRKEKVGLVPCGIPYIFGTIGSVDGNIM
CCCCEEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEECCCHHHHHHHCCCCCCEE
GTKPAENLGVEFMTAEVTSVDFEAKIVETASGESVQYDKLVFATGSIPVIPKIEGAELSG
CCCCCHHCCEEEEEEEEEEECEEEEEEECCCCCCEEECEEEEEECCCCEEECCCCCCCCE
VYAVPKNKEEIEKVYEAAKKAHNVIIIGGGFIGVEVGDEIRKMGKKVTIIEAKPHLLPAA
EEECCCCHHHHHHHHHHHHHHCCEEEEECCEEEEECCHHHHHCCCEEEEEECCCCCCCHH
FDESFGKLMEENLKEKNVVVMTETLVTKILGTDKVEGVELSSGEKLSTDMVIFAVGYKPN
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCEECCCCCEECCCEEEEEECCCCC
TELVKKLPIHLGYSGSIWVDEYMRTSVKDVFAVGDCAEHKDFFTRKPSKLMLASTAAFDA
HHHHHHCCEEECCCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCE
RVAGANLYTLKVVRENHGNLGVFSTSVEGLTLGAAGMTYKTACEEGFECVVGEAKSIDRH
EECCCEEEEEEEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHCCCEEEECCCCCCCCC
PGTLPDKSSLYVMLIFSKESGILLGAQIAGGKSVGEMINILGLGLQMGVTANDLVTMQIG
CCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHCCEEECCCCCCEEEEEEC
THPLLTSAPTVYPIITAAEAAIRKLRAE
CCCCCCCCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]