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The map label for this gene is bglA [H]

Identifier: 239617422

GI number: 239617422

Start: 1100587

End: 1101948

Strand: Reverse

Name: bglA [H]

Synonym: Kole_1034

Alternate gene names: 239617422

Gene position: 1101948-1100587 (Counterclockwise)

Preceding gene: 239617423

Following gene: 239617421

Centisome position: 47.87

GC content: 42.0

Gene sequence:

>1362_bases
TTGCCTGAAAACAGGGTTTCCGCAGAAGATTTTCCGGAAGGTTTTTTATGGGGAGTTGCTTCCTCTTCTTACCAGATAGA
AGGAGCAGATCTCGAGGACGGAAAGGGACCCTCTATCTGGACTGAATATACTAAATATAAGGACAACATAGTTGACGGCG
AAAGTGGTATGATTGCCTGTGACCATTATCACAGGTACACAGAGGATATTTTTTTGATGCAAGATTTAGGAGCTAACGCT
TATCGGTTTTCCGTTTCCTGGCCAAGAATATTTCCAGACGGCTATGGAAAACCAAATCCTTTCGGCCTGGATTTTTACGA
TCGACTTATTGACAATCTGCTTGAAGCCGGCATAACTCCCTTCCTCACCCTTTATCATTACGATCTTCCGTTGAAACTTC
AACAAGAGCACCGTGGATGGGAATCAAGAGAGACAATATCCTATTTCTTAGAATACGCTCATTTTCTCTTCAAAAAGTTT
GGAGACCGCGTAAAGTACTGGATAACGTTGAATCAACCTCTAAGAATCTCTCATCGGAGTTACATCGATGGGAAGGCAGC
CCCAGGAAAGGGAAAGTCTCCAAAAGACTCCTTTCAGGTTGCTCATCACCTGCTCTTAGCTCATGCTGGTGCAACAAAAA
TAATGAAGCAGGAGATACCAGATGGAAAAATTGGCATCTCTAATTCATCGATATACGTGGAACCAATAGAAGATACTCCT
GAACATAAAAGAGCAGCACTGTTGCTTGATCAATTCTATAACGACTGGTTTTATCTACCACCCGTAAGCGGAAAATACCC
TGAAGAACTCATGCTGGAACTCAAAAAACGTGGTTGGGCACCAGAGATGGAACCGGATGATATGGACAACATCGTTGCAG
AGCAGGATTTCTGGGGAATTAATTACTATACCAGAGCACTTGCAATCCAATCAAATAATTCTCTTCTCGGCTTTGCTCAG
GCATCTCCCAAATTTCCTGCAACCAGACGGGGAGCTGAGATCTATCCATGTGGACTCTTTCTCGTACTCAAGAAAATTCA
CAAAAACTTCGACAGCAAACAAATTTACATAACGGAGAATGGTATGGACCTCGACTCTCCTGTTGCTTCAGGAAAGCTCG
AGGATACAGAGAGAATTATTTTTCTGAAAGAACACATTGTTCAGCTCAAAAAAGCCGTTGACTCTGGAATACCCATCAAG
GGTTATTTTGTGTGGTCGTTGCTCGATAATTTCGAATGGACAAGTGGTTATACGCTGAAATTTGGATTGGTGTATGTGGA
TAGAAACAATGGACTCAAAAGAATCCCCAAGGCCAGTTATTATTTTTACCGTGATTTTATCGCCGGAAAAATTTCATTAT
AA

Upstream 100 bases:

>100_bases
ATACTCGCACTAGAAGGTAGAAAAACCGTTGAGAAAAGCTTCTCCTGGGAAGCCATCACAAACCAGATAGAAGAAATCTA
TGAAAGGACGTTGAGCAATC

Downstream 100 bases:

>100_bases
ACAAATTAGTGAGTCTGGGAGGTGCAGTTTTTGAAAGCCTGTGTCGTTATACCGACCTACTGGGGGCCTATAGATGGCAG
CGAAGAAATTATCTTCGATC

Product: beta-galactosidase

Products: NA

Alternate protein names: Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MPENRVSAEDFPEGFLWGVASSSYQIEGADLEDGKGPSIWTEYTKYKDNIVDGESGMIACDHYHRYTEDIFLMQDLGANA
YRFSVSWPRIFPDGYGKPNPFGLDFYDRLIDNLLEAGITPFLTLYHYDLPLKLQQEHRGWESRETISYFLEYAHFLFKKF
GDRVKYWITLNQPLRISHRSYIDGKAAPGKGKSPKDSFQVAHHLLLAHAGATKIMKQEIPDGKIGISNSSIYVEPIEDTP
EHKRAALLLDQFYNDWFYLPPVSGKYPEELMLELKKRGWAPEMEPDDMDNIVAEQDFWGINYYTRALAIQSNNSLLGFAQ
ASPKFPATRRGAEIYPCGLFLVLKKIHKNFDSKQIYITENGMDLDSPVASGKLEDTERIIFLKEHIVQLKKAVDSGIPIK
GYFVWSLLDNFEWTSGYTLKFGLVYVDRNNGLKRIPKASYYFYRDFIAGKISL

Sequences:

>Translated_453_residues
MPENRVSAEDFPEGFLWGVASSSYQIEGADLEDGKGPSIWTEYTKYKDNIVDGESGMIACDHYHRYTEDIFLMQDLGANA
YRFSVSWPRIFPDGYGKPNPFGLDFYDRLIDNLLEAGITPFLTLYHYDLPLKLQQEHRGWESRETISYFLEYAHFLFKKF
GDRVKYWITLNQPLRISHRSYIDGKAAPGKGKSPKDSFQVAHHLLLAHAGATKIMKQEIPDGKIGISNSSIYVEPIEDTP
EHKRAALLLDQFYNDWFYLPPVSGKYPEELMLELKKRGWAPEMEPDDMDNIVAEQDFWGINYYTRALAIQSNNSLLGFAQ
ASPKFPATRRGAEIYPCGLFLVLKKIHKNFDSKQIYITENGMDLDSPVASGKLEDTERIIFLKEHIVQLKKAVDSGIPIK
GYFVWSLLDNFEWTSGYTLKFGLVYVDRNNGLKRIPKASYYFYRDFIAGKISL
>Mature_452_residues
PENRVSAEDFPEGFLWGVASSSYQIEGADLEDGKGPSIWTEYTKYKDNIVDGESGMIACDHYHRYTEDIFLMQDLGANAY
RFSVSWPRIFPDGYGKPNPFGLDFYDRLIDNLLEAGITPFLTLYHYDLPLKLQQEHRGWESRETISYFLEYAHFLFKKFG
DRVKYWITLNQPLRISHRSYIDGKAAPGKGKSPKDSFQVAHHLLLAHAGATKIMKQEIPDGKIGISNSSIYVEPIEDTPE
HKRAALLLDQFYNDWFYLPPVSGKYPEELMLELKKRGWAPEMEPDDMDNIVAEQDFWGINYYTRALAIQSNNSLLGFAQA
SPKFPATRRGAEIYPCGLFLVLKKIHKNFDSKQIYITENGMDLDSPVASGKLEDTERIIFLKEHIVQLKKAVDSGIPIKG
YFVWSLLDNFEWTSGYTLKFGLVYVDRNNGLKRIPKASYYFYRDFIAGKISL

Specific function: Can Hydrolyze Salicin And Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=468, Percent_Identity=38.6752136752137, Blast_Score=292, Evalue=5e-79,
Organism=Homo sapiens, GI110681710, Length=474, Percent_Identity=36.0759493670886, Blast_Score=265, Evalue=5e-71,
Organism=Homo sapiens, GI13273313, Length=462, Percent_Identity=35.4978354978355, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI24497614, Length=460, Percent_Identity=33.2608695652174, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI28376633, Length=454, Percent_Identity=32.3788546255507, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI190360571, Length=85, Percent_Identity=41.1764705882353, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI2367270, Length=465, Percent_Identity=32.4731182795699, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1789070, Length=473, Percent_Identity=31.2896405919662, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI2367174, Length=470, Percent_Identity=30, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17539390, Length=469, Percent_Identity=31.1300639658849, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17552856, Length=468, Percent_Identity=31.4102564102564, Blast_Score=214, Evalue=5e-56,
Organism=Drosophila melanogaster, GI21356577, Length=462, Percent_Identity=34.6320346320346, Blast_Score=257, Evalue=9e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 52091; Mature: 51959

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENRVSAEDFPEGFLWGVASSSYQIEGADLEDGKGPSIWTEYTKYKDNIVDGESGMIAC
CCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEE
DHYHRYTEDIFLMQDLGANAYRFSVSWPRIFPDGYGKPNPFGLDFYDRLIDNLLEAGITP
HHHHHHHHHEEEEHHCCCCEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
FLTLYHYDLPLKLQQEHRGWESRETISYFLEYAHFLFKKFGDRVKYWITLNQPLRISHRS
EEEEEECCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCC
YIDGKAAPGKGKSPKDSFQVAHHLLLAHAGATKIMKQEIPDGKIGISNSSIYVEPIEDTP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCEEEEEECCCCC
EHKRAALLLDQFYNDWFYLPPVSGKYPEELMLELKKRGWAPEMEPDDMDNIVAEQDFWGI
CHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCC
NYYTRALAIQSNNSLLGFAQASPKFPATRRGAEIYPCGLFLVLKKIHKNFDSKQIYITEN
CEEEEEEEEECCCCEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHCCCCCCEEEEEEC
GMDLDSPVASGKLEDTERIIFLKEHIVQLKKAVDSGIPIKGYFVWSLLDNFEWTSGYTLK
CCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHCCCCEEHEEHEEHHHCCCCCCCCEEE
FGLVYVDRNNGLKRIPKASYYFYRDFIAGKISL
EEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PENRVSAEDFPEGFLWGVASSSYQIEGADLEDGKGPSIWTEYTKYKDNIVDGESGMIAC
CCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEE
DHYHRYTEDIFLMQDLGANAYRFSVSWPRIFPDGYGKPNPFGLDFYDRLIDNLLEAGITP
HHHHHHHHHEEEEHHCCCCEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
FLTLYHYDLPLKLQQEHRGWESRETISYFLEYAHFLFKKFGDRVKYWITLNQPLRISHRS
EEEEEECCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCC
YIDGKAAPGKGKSPKDSFQVAHHLLLAHAGATKIMKQEIPDGKIGISNSSIYVEPIEDTP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCEEEEEECCCCC
EHKRAALLLDQFYNDWFYLPPVSGKYPEELMLELKKRGWAPEMEPDDMDNIVAEQDFWGI
CHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCC
NYYTRALAIQSNNSLLGFAQASPKFPATRRGAEIYPCGLFLVLKKIHKNFDSKQIYITEN
CEEEEEEEEECCCCEEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHCCCCCCEEEEEEC
GMDLDSPVASGKLEDTERIIFLKEHIVQLKKAVDSGIPIKGYFVWSLLDNFEWTSGYTLK
CCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHCCCCEEHEEHEEHHHCCCCCCCCEEE
FGLVYVDRNNGLKRIPKASYYFYRDFIAGKISL
EEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8277941 [H]