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The map label for this gene is yaeL [C]

Identifier: 239617301

GI number: 239617301

Start: 961625

End: 963139

Strand: Direct

Name: yaeL [C]

Synonym: Kole_0910

Alternate gene names: 239617301

Gene position: 961625-963139 (Clockwise)

Preceding gene: 239617300

Following gene: 239617302

Centisome position: 41.77

GC content: 40.13

Gene sequence:

>1515_bases
ATGCTCACGTTAGTTTACTTTTTTCTTATACTGACGGCGATAGTCGTTGTTCATGAGTTCGGACATTATCTTTTCGCAAG
GATTTTTGGTGTTAGGGCCTTAGAATTTGCTGTTGGATTTGGCCCCAGAATTTTTTCTAAAAAAGGCAAAAAAACAGAAT
TCAGAATAAACGTTCTTCCTCTAGGAGGATATGTGAAACTTGCTGGTGAAGATTTTGGAGAACTTTCTGAAGAAATTCCC
GAAGACGAGCTTTTTTCCAACAAACCCTCATGGCAACGTTTCCTGATAGCTTTTGCCGGACCGTTATTTTCGATAATAGC
TGGATTTATTATATTCGCTCTTGTTGGGGCGTTCTGGGGTTTCCCTGAAGTTCGTATCGAACAGGTGGAACCAGGTACTC
CGGCATATTACGCCGGTTTAGAGGCTGGAGATAGAATTCTTGAGGTTAACGGCAGGGTCCTGATTCAGGAAAATACTCTC
AGTGATCTCATTTCGAAAGGTAAAGAGTTGACTCTAACAATCGAAAGAGACGGAAAAGAACTTCAACTGAACGTGAAGCC
AGCTCTCTTTCCCGAAGAAGCTATTCTCGTGATCAAAGATGCTGAGATGATACCAGAAGAAGGAAGTATTATCGAATTAT
TCAACGGAGTACCTTTTGATGGGAAATACAGCGATTTCTCCAGCGTTTTAACTCCTGAGAATACCATCAAGATAACCTTT
AAAGATGGTACTCAGCTTTCCGGGGTAATTGAAGGTGTTTCGGTTACCAAAGAGAGGTATGCAATTGGAATATATTACAG
CAATTTCGAGCCTGTTCTGAACAAGGACTTTGGAAGATTTAAGGCTGGTGACAGAATTCTCGAAGTCAACGGCATGAAAC
TCGAAAATGGAGTTGATCTATCAAGGCTGGCTCAAATAATAGGTTTGAATGAAAATCAGCTTTTCATCCACCTTTCAGGG
AATAAAATGGAATGGTTTGGTAGAGGATTACCGGATGAATTGACCATTAAGGTTCTTCGCAATGGTAAAGAACTAACGCT
GGAAACAAGTAAAACTGAAATAACCAATCTGATGAAAGAACCCAATGTTTTCCAGCTTGGTTATTCTTACTGGTATCCCA
AAAATGTATTTCATGCCTTTTCTTTGGGTTTCAAATGGGCTAACGAGCTTTTATTCTCAATGGTCAAGATACTTTCACGG
TTATTCACCGGTGGGACCAGTCTGAATGAGTTTTCAGGACCTATCGGAATGGTTACCCTTGTCAGTCAGGCAACAAAAGC
GGGGTTAAAAACCATCCTAATCCTTGTTGGATTCATTACCCTGAACATAGGTGTCATAAACCTGCTTCCCCTTCCAGCTC
TCGATGGTGGGAGAATGGTTCTGGCGTTCGTTGAAATGGTTACTAGAAAAAGAATTGATCCAAAGGTAGAAGGTTATATT
CACACAATCGGGTTTATAATAATTATGGGAATTTTAATCTACATAACCTTTATAGATATAGGAAGATTTCTGTGA

Upstream 100 bases:

>100_bases
AAACTATCGAGCGTATTGAACCGATAAGTCCTAAAGACTTCGAAGAGGTTCAGGCTATCGATGTATTGGCAAGAAAAATT
GCACAGGAAGAGGTGAGAAA

Downstream 100 bases:

>100_bases
GCAGAATAATAAAAATTGGGAATGTTGAAATAGGCGGAAATAACCCTATCGTAATTCAATCTATGACAAATACCAAGACC
GCAGACGTAAATGCCACTAT

Product: peptidase M50

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MLTLVYFFLILTAIVVVHEFGHYLFARIFGVRALEFAVGFGPRIFSKKGKKTEFRINVLPLGGYVKLAGEDFGELSEEIP
EDELFSNKPSWQRFLIAFAGPLFSIIAGFIIFALVGAFWGFPEVRIEQVEPGTPAYYAGLEAGDRILEVNGRVLIQENTL
SDLISKGKELTLTIERDGKELQLNVKPALFPEEAILVIKDAEMIPEEGSIIELFNGVPFDGKYSDFSSVLTPENTIKITF
KDGTQLSGVIEGVSVTKERYAIGIYYSNFEPVLNKDFGRFKAGDRILEVNGMKLENGVDLSRLAQIIGLNENQLFIHLSG
NKMEWFGRGLPDELTIKVLRNGKELTLETSKTEITNLMKEPNVFQLGYSYWYPKNVFHAFSLGFKWANELLFSMVKILSR
LFTGGTSLNEFSGPIGMVTLVSQATKAGLKTILILVGFITLNIGVINLLPLPALDGGRMVLAFVEMVTRKRIDPKVEGYI
HTIGFIIIMGILIYITFIDIGRFL

Sequences:

>Translated_504_residues
MLTLVYFFLILTAIVVVHEFGHYLFARIFGVRALEFAVGFGPRIFSKKGKKTEFRINVLPLGGYVKLAGEDFGELSEEIP
EDELFSNKPSWQRFLIAFAGPLFSIIAGFIIFALVGAFWGFPEVRIEQVEPGTPAYYAGLEAGDRILEVNGRVLIQENTL
SDLISKGKELTLTIERDGKELQLNVKPALFPEEAILVIKDAEMIPEEGSIIELFNGVPFDGKYSDFSSVLTPENTIKITF
KDGTQLSGVIEGVSVTKERYAIGIYYSNFEPVLNKDFGRFKAGDRILEVNGMKLENGVDLSRLAQIIGLNENQLFIHLSG
NKMEWFGRGLPDELTIKVLRNGKELTLETSKTEITNLMKEPNVFQLGYSYWYPKNVFHAFSLGFKWANELLFSMVKILSR
LFTGGTSLNEFSGPIGMVTLVSQATKAGLKTILILVGFITLNIGVINLLPLPALDGGRMVLAFVEMVTRKRIDPKVEGYI
HTIGFIIIMGILIYITFIDIGRFL
>Mature_504_residues
MLTLVYFFLILTAIVVVHEFGHYLFARIFGVRALEFAVGFGPRIFSKKGKKTEFRINVLPLGGYVKLAGEDFGELSEEIP
EDELFSNKPSWQRFLIAFAGPLFSIIAGFIIFALVGAFWGFPEVRIEQVEPGTPAYYAGLEAGDRILEVNGRVLIQENTL
SDLISKGKELTLTIERDGKELQLNVKPALFPEEAILVIKDAEMIPEEGSIIELFNGVPFDGKYSDFSSVLTPENTIKITF
KDGTQLSGVIEGVSVTKERYAIGIYYSNFEPVLNKDFGRFKAGDRILEVNGMKLENGVDLSRLAQIIGLNENQLFIHLSG
NKMEWFGRGLPDELTIKVLRNGKELTLETSKTEITNLMKEPNVFQLGYSYWYPKNVFHAFSLGFKWANELLFSMVKILSR
LFTGGTSLNEFSGPIGMVTLVSQATKAGLKTILILVGFITLNIGVINLLPLPALDGGRMVLAFVEMVTRKRIDPKVEGYI
HTIGFIIIMGILIYITFIDIGRFL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=516, Percent_Identity=25, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 56305; Mature: 56305

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLVYFFLILTAIVVVHEFGHYLFARIFGVRALEFAVGFGPRIFSKKGKKTEFRINVLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEE
LGGYVKLAGEDFGELSEEIPEDELFSNKPSWQRFLIAFAGPLFSIIAGFIIFALVGAFWG
CCCEEEECCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPEVRIEQVEPGTPAYYAGLEAGDRILEVNGRVLIQENTLSDLISKGKELTLTIERDGKE
CCCCEEEEECCCCCCEEECCCCCCEEEEECCEEEEECCCHHHHHHCCCEEEEEEECCCCE
LQLNVKPALFPEEAILVIKDAEMIPEEGSIIELFNGVPFDGKYSDFSSVLTPENTIKITF
EEEEECCCCCCCCEEEEEECHHHCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCEEEEEE
KDGTQLSGVIEGVSVTKERYAIGIYYSNFEPVLNKDFGRFKAGDRILEVNGMKLENGVDL
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHCCCCCCCCCCCEEEEECCEEECCCCCH
SRLAQIIGLNENQLFIHLSGNKMEWFGRGLPDELTIKVLRNGKELTLETSKTEITNLMKE
HHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHCC
PNVFQLGYSYWYPKNVFHAFSLGFKWANELLFSMVKILSRLFTGGTSLNEFSGPIGMVTL
CCEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHH
VSQATKAGLKTILILVGFITLNIGVINLLPLPALDGGRMVLAFVEMVTRKRIDPKVEGYI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
HTIGFIIIMGILIYITFIDIGRFL
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTLVYFFLILTAIVVVHEFGHYLFARIFGVRALEFAVGFGPRIFSKKGKKTEFRINVLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEE
LGGYVKLAGEDFGELSEEIPEDELFSNKPSWQRFLIAFAGPLFSIIAGFIIFALVGAFWG
CCCEEEECCCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPEVRIEQVEPGTPAYYAGLEAGDRILEVNGRVLIQENTLSDLISKGKELTLTIERDGKE
CCCCEEEEECCCCCCEEECCCCCCEEEEECCEEEEECCCHHHHHHCCCEEEEEEECCCCE
LQLNVKPALFPEEAILVIKDAEMIPEEGSIIELFNGVPFDGKYSDFSSVLTPENTIKITF
EEEEECCCCCCCCEEEEEECHHHCCCCCCEEEEECCCCCCCCCCCHHHHCCCCCEEEEEE
KDGTQLSGVIEGVSVTKERYAIGIYYSNFEPVLNKDFGRFKAGDRILEVNGMKLENGVDL
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHCCCCCCCCCCCEEEEECCEEECCCCCH
SRLAQIIGLNENQLFIHLSGNKMEWFGRGLPDELTIKVLRNGKELTLETSKTEITNLMKE
HHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHCC
PNVFQLGYSYWYPKNVFHAFSLGFKWANELLFSMVKILSRLFTGGTSLNEFSGPIGMVTL
CCEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHH
VSQATKAGLKTILILVGFITLNIGVINLLPLPALDGGRMVLAFVEMVTRKRIDPKVEGYI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
HTIGFIIIMGILIYITFIDIGRFL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]