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The map label for this gene is rnhB [H]

Identifier: 239617249

GI number: 239617249

Start: 904935

End: 905618

Strand: Direct

Name: rnhB [H]

Synonym: Kole_0857

Alternate gene names: 239617249

Gene position: 904935-905618 (Clockwise)

Preceding gene: 239617242

Following gene: 239617250

Centisome position: 39.31

GC content: 41.81

Gene sequence:

>684_bases
ATGAGATGTGAAAATACAGAAGAACTGCTTGATTTTGATAGAATGTACATTGAGAAGTTTGGCGTGATAGCGGGTCTGGA
CGAAGCCGGACGTGGCCCTTTAGCGGGACCTGTTGTAGCAGCAGCGGTTATCCTCGGCGAAAAAATTGAGGGATTATTCG
ACTCGAAAGCACTAACTGAGAAAGTCAGAGAAGAACTATTCGATAAGATTATAAAAAAAGCAAAGGTTGGTATCGGACTA
TCCAGTCCCGACGAGATAGATACATTCAATATCTTTGAAGCAACGAAACTCGCCATGAATCGTGCCATTAAAAAATTACC
AATACAACCCGATTATGTGATTATCGATGGAAAACACTTGAAGTTGAACAACAGAGGTGAGTGTATTGTTTCCGGAGATC
AAAAAAGCGCTTCCATAGCTGCAGCCTCTATTGTGGCAAAGGTATTCAGAGATAGATTGATGAAAGCATTGGCAGTGCTC
TATCCTGAATATTCGTGGGACAAAAACAAAGGTTACGGTACCGCAGAACATTTGAAAGCTTTAAAAATCTACGGCCCAAC
CTTGTGGCACAGATTAACCTTCAGCCCGGTAAAGGCGCTGCTCAACAGAGAGATCGTTTTATCTTGGTTGCAAAATGATG
TCATATCTGAACGAAGGCTTTTCAGAGTTGGAATGTTGTTTTAG

Upstream 100 bases:

>100_bases
AACATTATACAATGGAACAGATACAACAGTACCAAGGAAAGGAGGCGCAACCCCTCTCTTCTTTTCTCTAAGATGAAGAG
TACCCGAATGTTGAAACCTT

Downstream 100 bases:

>100_bases
CGGAGGTAGAATCGCGTGGAAACCGGAAAACGTTTTGAAAAATTGGTTGAACTGATGCGAATACTCAGAAGTAAAAAGGG
TTGTGAATGGGACAGAGAAC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRCENTEELLDFDRMYIEKFGVIAGLDEAGRGPLAGPVVAAAVILGEKIEGLFDSKALTEKVREELFDKIIKKAKVGIGL
SSPDEIDTFNIFEATKLAMNRAIKKLPIQPDYVIIDGKHLKLNNRGECIVSGDQKSASIAAASIVAKVFRDRLMKALAVL
YPEYSWDKNKGYGTAEHLKALKIYGPTLWHRLTFSPVKALLNREIVLSWLQNDVISERRLFRVGMLF

Sequences:

>Translated_227_residues
MRCENTEELLDFDRMYIEKFGVIAGLDEAGRGPLAGPVVAAAVILGEKIEGLFDSKALTEKVREELFDKIIKKAKVGIGL
SSPDEIDTFNIFEATKLAMNRAIKKLPIQPDYVIIDGKHLKLNNRGECIVSGDQKSASIAAASIVAKVFRDRLMKALAVL
YPEYSWDKNKGYGTAEHLKALKIYGPTLWHRLTFSPVKALLNREIVLSWLQNDVISERRLFRVGMLF
>Mature_227_residues
MRCENTEELLDFDRMYIEKFGVIAGLDEAGRGPLAGPVVAAAVILGEKIEGLFDSKALTEKVREELFDKIIKKAKVGIGL
SSPDEIDTFNIFEATKLAMNRAIKKLPIQPDYVIIDGKHLKLNNRGECIVSGDQKSASIAAASIVAKVFRDRLMKALAVL
YPEYSWDKNKGYGTAEHLKALKIYGPTLWHRLTFSPVKALLNREIVLSWLQNDVISERRLFRVGMLF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=185, Percent_Identity=48.6486486486487, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 25439; Mature: 25439

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCENTEELLDFDRMYIEKFGVIAGLDEAGRGPLAGPVVAAAVILGEKIEGLFDSKALTE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVREELFDKIIKKAKVGIGLSSPDEIDTFNIFEATKLAMNRAIKKLPIQPDYVIIDGKHL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEE
KLNNRGECIVSGDQKSASIAAASIVAKVFRDRLMKALAVLYPEYSWDKNKGYGTAEHLKA
EECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
LKIYGPTLWHRLTFSPVKALLNREIVLSWLQNDVISERRLFRVGMLF
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRCENTEELLDFDRMYIEKFGVIAGLDEAGRGPLAGPVVAAAVILGEKIEGLFDSKALTE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVREELFDKIIKKAKVGIGLSSPDEIDTFNIFEATKLAMNRAIKKLPIQPDYVIIDGKHL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEE
KLNNRGECIVSGDQKSASIAAASIVAKVFRDRLMKALAVLYPEYSWDKNKGYGTAEHLKA
EECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
LKIYGPTLWHRLTFSPVKALLNREIVLSWLQNDVISERRLFRVGMLF
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]