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The map label for this gene is cscK [H]

Identifier: 239617010

GI number: 239617010

Start: 656515

End: 657486

Strand: Direct

Name: cscK [H]

Synonym: Kole_0610

Alternate gene names: 239617010

Gene position: 656515-657486 (Clockwise)

Preceding gene: 239617009

Following gene: 239617012

Centisome position: 28.52

GC content: 43.0

Gene sequence:

>972_bases
ATGGCGAAACCTGTATTATGCGCTGGAGAAGTTTTGCTTGACTTCTTATCCAAGAACCCCGGAGCCGGTCTTGATGAAAC
CACACTCTTTGAAAAAAGGCCGGGAGGTTCTCCCTTCAATATCGCGGTGGGATTGCGAAGGCTCGGGGTACCCGTGGCAT
TTCTTGGAAAGGTGGGAACAGACGAATTCGGAGACGCTCTTTTCTCATACCTTGCTTCTGAGGGAATCGATACCCGTTTC
GTTGTCAGAAGCCCCGGTACAAAAACCTCTCTTGCCTTCGCTGCAATAGACAAGCACGGAAAACCTGTATTCAGATTTTA
CCGTGACAACGCCGCGGATGTGAGCTTAAAAATAACGGAAATTCCGGATATCAACCCGCAAGATTTCTCTCTGTACCACT
GCGGGTCAATATCCTTACTGGAGGAACCTTCAGCGAGTACTTACCTCGAAATCTTCAGGCGATTCGTAAAATCCGGCATA
AAAACATCTTTTGATCCAAATATAAGAAGAAGCCTTATAAAGAACGAAAAGAACTACCGAATGTTATTGAATGAAATTAT
TTCCAATGCCGATATTATCAAATTGAGCGATGAGGATCTGGAATACATAACAGGCGAAAAGAACCCGGAAAAAGCTGTCA
ATAAACTTCTTACAAAAAGCAATGCCATTATATTCGTAACCCTCGGAAGTAAGGGTTCGTTGGTTTGCAAGGACAAAGAG
ATTTCCCATGTTCCCGGTTATAACGTCAAGGTTTTAGAAACAACAGGATGCGGGGATTCATTCATGGCAGCTGTTTTATC
CCATATATACAAACTAAACAGTGAAGAATTTGTGCGGTTATCTATCATGGAGCTTGAAAAAATAGCAAAGTTTGCCAATG
CCGAAGCTGCCATAGTAGCTACCAGATATGGCGCCGCAAATTCAATGCCGTATAAACAAGAGGTCGAAACATTCTTTTTG
AAAGACCTATAA

Upstream 100 bases:

>100_bases
CACCTTACCATTGAATCTTGCTAAAGAATTCGTCAAAGGTGATTTCCCGATGAACGATCTTGAGATCTTTGAAAATGAAT
TCAGGATGTGAGGTTGGGTT

Downstream 100 bases:

>100_bases
GCTTTTAAAGATCAGGGACCAGGATAAGGAAGAACAAAAAACACCATTACGGCAAAGAATGTTATATTGCCCAGAAGTAC
CATAATATGCCAGATTTCGT

Product: PfkB domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAKPVLCAGEVLLDFLSKNPGAGLDETTLFEKRPGGSPFNIAVGLRRLGVPVAFLGKVGTDEFGDALFSYLASEGIDTRF
VVRSPGTKTSLAFAAIDKHGKPVFRFYRDNAADVSLKITEIPDINPQDFSLYHCGSISLLEEPSASTYLEIFRRFVKSGI
KTSFDPNIRRSLIKNEKNYRMLLNEIISNADIIKLSDEDLEYITGEKNPEKAVNKLLTKSNAIIFVTLGSKGSLVCKDKE
ISHVPGYNVKVLETTGCGDSFMAAVLSHIYKLNSEEFVRLSIMELEKIAKFANAEAAIVATRYGAANSMPYKQEVETFFL
KDL

Sequences:

>Translated_323_residues
MAKPVLCAGEVLLDFLSKNPGAGLDETTLFEKRPGGSPFNIAVGLRRLGVPVAFLGKVGTDEFGDALFSYLASEGIDTRF
VVRSPGTKTSLAFAAIDKHGKPVFRFYRDNAADVSLKITEIPDINPQDFSLYHCGSISLLEEPSASTYLEIFRRFVKSGI
KTSFDPNIRRSLIKNEKNYRMLLNEIISNADIIKLSDEDLEYITGEKNPEKAVNKLLTKSNAIIFVTLGSKGSLVCKDKE
ISHVPGYNVKVLETTGCGDSFMAAVLSHIYKLNSEEFVRLSIMELEKIAKFANAEAAIVATRYGAANSMPYKQEVETFFL
KDL
>Mature_322_residues
AKPVLCAGEVLLDFLSKNPGAGLDETTLFEKRPGGSPFNIAVGLRRLGVPVAFLGKVGTDEFGDALFSYLASEGIDTRFV
VRSPGTKTSLAFAAIDKHGKPVFRFYRDNAADVSLKITEIPDINPQDFSLYHCGSISLLEEPSASTYLEIFRRFVKSGIK
TSFDPNIRRSLIKNEKNYRMLLNEIISNADIIKLSDEDLEYITGEKNPEKAVNKLLTKSNAIIFVTLGSKGSLVCKDKEI
SHVPGYNVKVLETTGCGDSFMAAVLSHIYKLNSEEFVRLSIMELEKIAKFANAEAAIVATRYGAANSMPYKQEVETFFLK
DL

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=289, Percent_Identity=25.2595155709343, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87082343, Length=280, Percent_Identity=25.3571428571429, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790193, Length=291, Percent_Identity=26.8041237113402, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082281, Length=321, Percent_Identity=25.5451713395639, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=26.5573770491803, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 35630; Mature: 35499

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPVLCAGEVLLDFLSKNPGAGLDETTLFEKRPGGSPFNIAVGLRRLGVPVAFLGKVGT
CCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCEEHHHHHHHHCCCCEECCCCCC
DEFGDALFSYLASEGIDTRFVVRSPGTKTSLAFAAIDKHGKPVFRFYRDNAADVSLKITE
CHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEE
IPDINPQDFSLYHCGSISLLEEPSASTYLEIFRRFVKSGIKTSFDPNIRRSLIKNEKNYR
CCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHH
MLLNEIISNADIIKLSDEDLEYITGEKNPEKAVNKLLTKSNAIIFVTLGSKGSLVCKDKE
HHHHHHHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEECCC
ISHVPGYNVKVLETTGCGDSFMAAVLSHIYKLNSEEFVRLSIMELEKIAKFANAEAAIVA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCEEEEE
TRYGAANSMPYKQEVETFFLKDL
EECCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKPVLCAGEVLLDFLSKNPGAGLDETTLFEKRPGGSPFNIAVGLRRLGVPVAFLGKVGT
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCEEHHHHHHHHCCCCEECCCCCC
DEFGDALFSYLASEGIDTRFVVRSPGTKTSLAFAAIDKHGKPVFRFYRDNAADVSLKITE
CHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEE
IPDINPQDFSLYHCGSISLLEEPSASTYLEIFRRFVKSGIKTSFDPNIRRSLIKNEKNYR
CCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHH
MLLNEIISNADIIKLSDEDLEYITGEKNPEKAVNKLLTKSNAIIFVTLGSKGSLVCKDKE
HHHHHHHCCCCEEEECCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEECCC
ISHVPGYNVKVLETTGCGDSFMAAVLSHIYKLNSEEFVRLSIMELEKIAKFANAEAAIVA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCEEEEE
TRYGAANSMPYKQEVETFFLKDL
EECCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA