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The map label for this gene is yicI [C]

Identifier: 239616986

GI number: 239616986

Start: 631488

End: 633758

Strand: Direct

Name: yicI [C]

Synonym: Kole_0585

Alternate gene names: 239616986

Gene position: 631488-633758 (Clockwise)

Preceding gene: 239616982

Following gene: 239616987

Centisome position: 27.43

GC content: 40.91

Gene sequence:

>2271_bases
ATGTTCACAACATATAGAAAATTTCCCAGCAGGATCCTGGAGATAACGTTCAAAAAAGATGGGGAGTCTGTTTTGCCAGA
AAGCCCTGCTGTTGTCATGAAACCCATGGCTACTGTGAATAACCTTATTTCTTTCAACTTTTTCAATTCCTGGTTGAAGA
AAGATTCGGAAAATCATTATTCCTTCAGTAGTACAAACGGATTATGGGGCGAAATGGAAATTCGAGAGAAACCGAAAGGG
TTTGAAATAAAAATAAGAATTGATCCGGAAGACGGCATCTTTGGTTTCGGTGAGGAAATCGGAGCTTTGAACAAACGGGG
TAAGGTGTATGAGATGTACAATACAGACGAACCAGACCATTCACCAACCAAAACTCGTCTCTACTCATCTTTTCCGGTTT
TCATGATCCTGTCACCAAAGAAATCTCTCGGATTCTTCCTCGACCACCCTGGTTACAGCAGATTTGATCTGGCTTTCACC
AAAGAAAATGAAATAATCATCAACGTTGAGGGTGAAGGGTTCAAACTTTATCTCCAGGGAACAACTCCTGATGAGATTAT
TAAAGCTTTTACTGAACTTACAGGAAAACCTCACTTCTTCCCGGTATGGATACTCGGATACCAACAGTCACGCTGGTCTT
ATCCTAACGAAGAAACTATAACTGATCTCGCGGAAAAGTTCAGGGAGAAGAAAATCCCCTGTGATGTTCTTTATCTCGAT
ATAGATTATATGGAGGATTTCAAGGTCTTCACATGGAATAAAAGAAGCTTCCCAAATCCAGAGAAACTGCTGGAAAAATT
AGAAAATCAGGGATTCAAGGTCATAACAATAATCGACCCCGGGGTAAAGATTCAAAAAGGTTACGAAATTTATGAACAGG
GGATTAAAAGAGATTATTTCTGCAAAAAACCGGATGGTTCACTGTTTGTCCCGTACGTATGGCCAGGACCATCTCACTTC
CCTGATTTCATGAATTCTAAAGTTCGTGAATGGTGGGGAAAGCTATGCAGTGATTTTACAAAAACGGGGATAGCGGGCAT
CTGGAATGACATGAATGAACCATCTATTTTTATGACAGCAGAATCTCTTCGTGAATTAAAAACGATTGTGAATAACATCG
AAGAAGATATGGGAATAGAAGCAGGATTTATTTTAAGCCAGCTTGATGGTCGAAAACGTTATAGAGACTACGGTGTCGAA
TTTCAACATACCGATGACACAGGCAAAAAATTTCTGAACAGACAGGTTCATAACCTCTTTGGATTCAACATGTCACGCGC
AACTTACGAAGGTTTTCAAAAAAGCGATCCCGATAGAAGGCCAGTTGTGATAACCCGTTCCGCTTATCCTGGAATTCAAC
GGTATGCCATTTTGTGGACGGGTGACAATGCCAGCCTATGGGAACATCTGTTAATGGAAATTCAAATGGCTCAGTCTCTT
GCACTCACTGGGGTGAATTTTATCGGTTGTGATGTTGGAGGATTTGGCGGTAATTCCTATGGGGAGCTTTTGGTAAGATG
GACCCAGTTTGGTGCGTTTCTGCCCTTCTTTAGAAATCACAGTGCCATAGGCACACGAAATCAGGAGCCATGGGTTTTCG
GCGAAGATGTTGAAGAGATTGTACGTAATTATATTGAACTCAGATATTCTCTAATGCCATACATTTATTCGATACTCAGA
ACAGCAACAGTAACGGGAATACCGATGGTCAGGCCTCTATTGCTTGAATGGCCTGACAACCCCCAGACTTATGAAACCGA
TGACGAATATCTATTTGGTCCAGCGCTTCTGGTGGCTCCTGTTTATCGTCCCAACGTCAGGGGTAGGTATGTTTACCTAC
CAGATGGAAAATGGATGGACTTTTTCGATGAAAAAATTTTGGATAGCGGCCATCACTACGTTGAAGCGCCTCTAGATAAA
ATGCCTCTATTTATACGTGAAAATTCGTTGATCCTGACAACAGAAGTCAACCAGTATCTTTCTAATGCAGTATGGAAGAC
AGTAAAAATAAAGGGATTTGTTACCACAGCTGCAAGTTTCGAGCTTTATGAAGATGATGGAATCAGCAGGAAATATCTTG
AAGATGAATATTCGCTGAAAAAGATAGAAGTCTGGAAGTCTGAAAACAACTACCTTGCAAGGATATATCCTCAGGAGGGA
AAACTTGAGATTCCAGCAAGAAAACTGAGTATAGAGATTTTTGATGGTAAGAGGTTCTGGAAAGGTGAAATCGAAGACAG
TAAAGAGGGGTTGTGCATAGAATTGCATTAA

Upstream 100 bases:

>100_bases
TTGTTATAACTTCCCGGAGGAAAACCGAAATCTGATTTAAGTCTACCATCATAGGTGTTACAATGTGAAATGTAGCACAC
AATGTATTGGAGGGGTACTA

Downstream 100 bases:

>100_bases
AAAACTAAGAAAAACGATAAAAGATAGATGGATTGGAGGTATCAGGGTGCTGGAGTTGAAAAATGTTTTTTTAGAAAGAG
AGAATAGGGTTATTATCAAA

Product: Alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MFTTYRKFPSRILEITFKKDGESVLPESPAVVMKPMATVNNLISFNFFNSWLKKDSENHYSFSSTNGLWGEMEIREKPKG
FEIKIRIDPEDGIFGFGEEIGALNKRGKVYEMYNTDEPDHSPTKTRLYSSFPVFMILSPKKSLGFFLDHPGYSRFDLAFT
KENEIIINVEGEGFKLYLQGTTPDEIIKAFTELTGKPHFFPVWILGYQQSRWSYPNEETITDLAEKFREKKIPCDVLYLD
IDYMEDFKVFTWNKRSFPNPEKLLEKLENQGFKVITIIDPGVKIQKGYEIYEQGIKRDYFCKKPDGSLFVPYVWPGPSHF
PDFMNSKVREWWGKLCSDFTKTGIAGIWNDMNEPSIFMTAESLRELKTIVNNIEEDMGIEAGFILSQLDGRKRYRDYGVE
FQHTDDTGKKFLNRQVHNLFGFNMSRATYEGFQKSDPDRRPVVITRSAYPGIQRYAILWTGDNASLWEHLLMEIQMAQSL
ALTGVNFIGCDVGGFGGNSYGELLVRWTQFGAFLPFFRNHSAIGTRNQEPWVFGEDVEEIVRNYIELRYSLMPYIYSILR
TATVTGIPMVRPLLLEWPDNPQTYETDDEYLFGPALLVAPVYRPNVRGRYVYLPDGKWMDFFDEKILDSGHHYVEAPLDK
MPLFIRENSLILTTEVNQYLSNAVWKTVKIKGFVTTAASFELYEDDGISRKYLEDEYSLKKIEVWKSENNYLARIYPQEG
KLEIPARKLSIEIFDGKRFWKGEIEDSKEGLCIELH

Sequences:

>Translated_756_residues
MFTTYRKFPSRILEITFKKDGESVLPESPAVVMKPMATVNNLISFNFFNSWLKKDSENHYSFSSTNGLWGEMEIREKPKG
FEIKIRIDPEDGIFGFGEEIGALNKRGKVYEMYNTDEPDHSPTKTRLYSSFPVFMILSPKKSLGFFLDHPGYSRFDLAFT
KENEIIINVEGEGFKLYLQGTTPDEIIKAFTELTGKPHFFPVWILGYQQSRWSYPNEETITDLAEKFREKKIPCDVLYLD
IDYMEDFKVFTWNKRSFPNPEKLLEKLENQGFKVITIIDPGVKIQKGYEIYEQGIKRDYFCKKPDGSLFVPYVWPGPSHF
PDFMNSKVREWWGKLCSDFTKTGIAGIWNDMNEPSIFMTAESLRELKTIVNNIEEDMGIEAGFILSQLDGRKRYRDYGVE
FQHTDDTGKKFLNRQVHNLFGFNMSRATYEGFQKSDPDRRPVVITRSAYPGIQRYAILWTGDNASLWEHLLMEIQMAQSL
ALTGVNFIGCDVGGFGGNSYGELLVRWTQFGAFLPFFRNHSAIGTRNQEPWVFGEDVEEIVRNYIELRYSLMPYIYSILR
TATVTGIPMVRPLLLEWPDNPQTYETDDEYLFGPALLVAPVYRPNVRGRYVYLPDGKWMDFFDEKILDSGHHYVEAPLDK
MPLFIRENSLILTTEVNQYLSNAVWKTVKIKGFVTTAASFELYEDDGISRKYLEDEYSLKKIEVWKSENNYLARIYPQEG
KLEIPARKLSIEIFDGKRFWKGEIEDSKEGLCIELH
>Mature_756_residues
MFTTYRKFPSRILEITFKKDGESVLPESPAVVMKPMATVNNLISFNFFNSWLKKDSENHYSFSSTNGLWGEMEIREKPKG
FEIKIRIDPEDGIFGFGEEIGALNKRGKVYEMYNTDEPDHSPTKTRLYSSFPVFMILSPKKSLGFFLDHPGYSRFDLAFT
KENEIIINVEGEGFKLYLQGTTPDEIIKAFTELTGKPHFFPVWILGYQQSRWSYPNEETITDLAEKFREKKIPCDVLYLD
IDYMEDFKVFTWNKRSFPNPEKLLEKLENQGFKVITIIDPGVKIQKGYEIYEQGIKRDYFCKKPDGSLFVPYVWPGPSHF
PDFMNSKVREWWGKLCSDFTKTGIAGIWNDMNEPSIFMTAESLRELKTIVNNIEEDMGIEAGFILSQLDGRKRYRDYGVE
FQHTDDTGKKFLNRQVHNLFGFNMSRATYEGFQKSDPDRRPVVITRSAYPGIQRYAILWTGDNASLWEHLLMEIQMAQSL
ALTGVNFIGCDVGGFGGNSYGELLVRWTQFGAFLPFFRNHSAIGTRNQEPWVFGEDVEEIVRNYIELRYSLMPYIYSILR
TATVTGIPMVRPLLLEWPDNPQTYETDDEYLFGPALLVAPVYRPNVRGRYVYLPDGKWMDFFDEKILDSGHHYVEAPLDK
MPLFIRENSLILTTEVNQYLSNAVWKTVKIKGFVTTAASFELYEDDGISRKYLEDEYSLKKIEVWKSENNYLARIYPQEG
KLEIPARKLSIEIFDGKRFWKGEIEDSKEGLCIELH

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=534, Percent_Identity=35.9550561797753, Blast_Score=339, Evalue=5e-93,
Organism=Homo sapiens, GI88900491, Length=654, Percent_Identity=31.651376146789, Blast_Score=333, Evalue=3e-91,
Organism=Homo sapiens, GI38202257, Length=654, Percent_Identity=31.651376146789, Blast_Score=333, Evalue=3e-91,
Organism=Homo sapiens, GI221316699, Length=711, Percent_Identity=29.817158931083, Blast_Score=281, Evalue=2e-75,
Organism=Homo sapiens, GI119393895, Length=646, Percent_Identity=29.5665634674923, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI119393893, Length=646, Percent_Identity=29.5665634674923, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI119393891, Length=646, Percent_Identity=29.5665634674923, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI157364974, Length=588, Percent_Identity=30.2721088435374, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI310115361, Length=533, Percent_Identity=31.7073170731707, Blast_Score=262, Evalue=7e-70,
Organism=Homo sapiens, GI153791946, Length=178, Percent_Identity=31.4606741573034, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI2367256, Length=573, Percent_Identity=23.7347294938918, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI2367323, Length=607, Percent_Identity=22.4052718286656, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71991189, Length=697, Percent_Identity=31.2769010043042, Blast_Score=318, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI17560798, Length=557, Percent_Identity=31.2387791741472, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17560800, Length=557, Percent_Identity=31.2387791741472, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI32563849, Length=620, Percent_Identity=27.741935483871, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71985706, Length=652, Percent_Identity=27.4539877300614, Blast_Score=228, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6319706, Length=612, Percent_Identity=32.3529411764706, Blast_Score=283, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24643749, Length=621, Percent_Identity=30.7568438003221, Blast_Score=304, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24643753, Length=621, Percent_Identity=30.7568438003221, Blast_Score=304, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24643751, Length=621, Percent_Identity=30.7568438003221, Blast_Score=304, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24643746, Length=621, Percent_Identity=30.7568438003221, Blast_Score=304, Evalue=2e-82,
Organism=Drosophila melanogaster, GI21357605, Length=621, Percent_Identity=30.7568438003221, Blast_Score=304, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24650054, Length=186, Percent_Identity=30.1075268817204, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571440, Length=471, Percent_Identity=22.0806794055202, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571438, Length=146, Percent_Identity=30.8219178082192, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 87911; Mature: 87911

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTTYRKFPSRILEITFKKDGESVLPESPAVVMKPMATVNNLISFNFFNSWLKKDSENHY
CCCCHHHHCCEEEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCE
SFSSTNGLWGEMEIREKPKGFEIKIRIDPEDGIFGFGEEIGALNKRGKVYEMYNTDEPDH
EECCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEECCCCCCCC
SPTKTRLYSSFPVFMILSPKKSLGFFLDHPGYSRFDLAFTKENEIIINVEGEGFKLYLQG
CCCHHEEECCCCEEEEECCCHHCCEEECCCCCCEEEEEEECCCEEEEEEECCCEEEEEEC
TTPDEIIKAFTELTGKPHFFPVWILGYQQSRWSYPNEETITDLAEKFREKKIPCDVLYLD
CCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
IDYMEDFKVFTWNKRSFPNPEKLLEKLENQGFKVITIIDPGVKIQKGYEIYEQGIKRDYF
ECCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEECCHHHHHHCCCCCCC
CKKPDGSLFVPYVWPGPSHFPDFMNSKVREWWGKLCSDFTKTGIAGIWNDMNEPSIFMTA
EECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEH
ESLRELKTIVNNIEEDMGIEAGFILSQLDGRKRYRDYGVEFQHTDDTGKKFLNRQVHNLF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
GFNMSRATYEGFQKSDPDRRPVVITRSAYPGIQRYAILWTGDNASLWEHLLMEIQMAQSL
CCCCCHHHHCCHHCCCCCCCCEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
ALTGVNFIGCDVGGFGGNSYGELLVRWTQFGAFLPFFRNHSAIGTRNQEPWVFGEDVEEI
HHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCHHHH
VRNYIELRYSLMPYIYSILRTATVTGIPMVRPLLLEWPDNPQTYETDDEYLFGPALLVAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHEEECCCCCCCCCCCCCEEECCHHEEEE
VYRPNVRGRYVYLPDGKWMDFFDEKILDSGHHYVEAPLDKMPLFIRENSLILTTEVNQYL
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCHHHCCEEEECCCEEEEECHHHHH
SNAVWKTVKIKGFVTTAASFELYEDDGISRKYLEDEYSLKKIEVWKSENNYLARIYPQEG
HHHHEEEEEEEEEEEEEEEEEEECCCCCCHHHHCCCCCCEEEEEEECCCCEEEEEECCCC
KLEIPARKLSIEIFDGKRFWKGEIEDSKEGLCIELH
CEECCCEEEEEEEECCCEEECCCCCCCCCCEEEEEC
>Mature Secondary Structure
MFTTYRKFPSRILEITFKKDGESVLPESPAVVMKPMATVNNLISFNFFNSWLKKDSENHY
CCCCHHHHCCEEEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCE
SFSSTNGLWGEMEIREKPKGFEIKIRIDPEDGIFGFGEEIGALNKRGKVYEMYNTDEPDH
EECCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEECCCCCCCC
SPTKTRLYSSFPVFMILSPKKSLGFFLDHPGYSRFDLAFTKENEIIINVEGEGFKLYLQG
CCCHHEEECCCCEEEEECCCHHCCEEECCCCCCEEEEEEECCCEEEEEEECCCEEEEEEC
TTPDEIIKAFTELTGKPHFFPVWILGYQQSRWSYPNEETITDLAEKFREKKIPCDVLYLD
CCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
IDYMEDFKVFTWNKRSFPNPEKLLEKLENQGFKVITIIDPGVKIQKGYEIYEQGIKRDYF
ECCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEECCHHHHHHCCCCCCC
CKKPDGSLFVPYVWPGPSHFPDFMNSKVREWWGKLCSDFTKTGIAGIWNDMNEPSIFMTA
EECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEH
ESLRELKTIVNNIEEDMGIEAGFILSQLDGRKRYRDYGVEFQHTDDTGKKFLNRQVHNLF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
GFNMSRATYEGFQKSDPDRRPVVITRSAYPGIQRYAILWTGDNASLWEHLLMEIQMAQSL
CCCCCHHHHCCHHCCCCCCCCEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
ALTGVNFIGCDVGGFGGNSYGELLVRWTQFGAFLPFFRNHSAIGTRNQEPWVFGEDVEEI
HHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCHHHH
VRNYIELRYSLMPYIYSILRTATVTGIPMVRPLLLEWPDNPQTYETDDEYLFGPALLVAP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHEEECCCCCCCCCCCCCEEECCHHEEEE
VYRPNVRGRYVYLPDGKWMDFFDEKILDSGHHYVEAPLDKMPLFIRENSLILTTEVNQYL
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCHHHCCEEEECCCEEEEECHHHHH
SNAVWKTVKIKGFVTTAASFELYEDDGISRKYLEDEYSLKKIEVWKSENNYLARIYPQEG
HHHHEEEEEEEEEEEEEEEEEEECCCCCCHHHHCCCCCCEEEEEEECCCCEEEEEECCCC
KLEIPARKLSIEIFDGKRFWKGEIEDSKEGLCIELH
CEECCCEEEEEEEECCCEEECCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]