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The map label for this gene is gpmA [H]

Identifier: 239616923

GI number: 239616923

Start: 568414

End: 569046

Strand: Direct

Name: gpmA [H]

Synonym: Kole_0519

Alternate gene names: 239616923

Gene position: 568414-569046 (Clockwise)

Preceding gene: 239616922

Following gene: 239616926

Centisome position: 24.69

GC content: 42.02

Gene sequence:

>633_bases
ATGGATTTGCTCCTTATCAGGCATGGACATTCTGTTGGAGACGATGAAAGACGAATTAAAGGAAGCTGGGATGTCGAACT
CACTCCAAAGGGTCTTAAACAGGCAAAGCTGCTCAAAGAAAGACTGGAAAAAGAGAATTACAAATGTGACCTTCTTTTTT
CAAGCCCATTGAAACGTGCAGCTCAAACTGCTGAAGCAGTTTCTCAGGCTGTGGGAAAGCCTATAATCTATGATTCAAGG
TTACGTGAACAGGATTCAGGAAAATTCGCGGGAATGACCAGGGAAGAGGCTTCAAAATTTAGTCCACCGCCAGATGAAAA
GGGTTACAGAAACTATGTTCCGATACCTGGTGGAGAATCACTGTTAGACCATATCCGCAGGGTGAGCGAATTCTATCTCG
AACTTATCGATAAGCATATGGATAAGCGAGTCTGTATAGTGACCCACGGTGGAACCATAAATGTATTGTTGCGGATCATT
TATAACCTGCCTGTGAATCAACCGTATGTGGATAAACACATCTATTTGTTTGCTATGAACGATACAGCTATGTCCAGATT
GATAATCAGAGGTCCACAGGATGTCATTACCTATTACCTTAATAATTTCAGCCACCTGACTGCGATAAAGTAA

Upstream 100 bases:

>100_bases
CTTATTGTTGCAAAGCTTGGAAGATTGAAACACCAGCGACTCTGGAAGCAATAAAGAATTTGGTGTGGTGCTGGAAAACT
AAGAGGTATGAGGTGATCGA

Downstream 100 bases:

>100_bases
TTTCATAAAATAAAAGAAAAAGCCTCCTTTTATTTTATGGGAGGCTTTTTTACATAATAAGCCGTTGATACATTTTAGTT
TTTTTGGTTCAATCTCATTT

Product: Phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MDLLLIRHGHSVGDDERRIKGSWDVELTPKGLKQAKLLKERLEKENYKCDLLFSSPLKRAAQTAEAVSQAVGKPIIYDSR
LREQDSGKFAGMTREEASKFSPPPDEKGYRNYVPIPGGESLLDHIRRVSEFYLELIDKHMDKRVCIVTHGGTINVLLRII
YNLPVNQPYVDKHIYLFAMNDTAMSRLIIRGPQDVITYYLNNFSHLTAIK

Sequences:

>Translated_210_residues
MDLLLIRHGHSVGDDERRIKGSWDVELTPKGLKQAKLLKERLEKENYKCDLLFSSPLKRAAQTAEAVSQAVGKPIIYDSR
LREQDSGKFAGMTREEASKFSPPPDEKGYRNYVPIPGGESLLDHIRRVSEFYLELIDKHMDKRVCIVTHGGTINVLLRII
YNLPVNQPYVDKHIYLFAMNDTAMSRLIIRGPQDVITYYLNNFSHLTAIK
>Mature_210_residues
MDLLLIRHGHSVGDDERRIKGSWDVELTPKGLKQAKLLKERLEKENYKCDLLFSSPLKRAAQTAEAVSQAVGKPIIYDSR
LREQDSGKFAGMTREEASKFSPPPDEKGYRNYVPIPGGESLLDHIRRVSEFYLELIDKHMDKRVCIVTHGGTINVLLRII
YNLPVNQPYVDKHIYLFAMNDTAMSRLIIRGPQDVITYYLNNFSHLTAIK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=212, Percent_Identity=27.8301886792453, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI4505753, Length=212, Percent_Identity=26.8867924528302, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790856, Length=172, Percent_Identity=32.5581395348837, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786970, Length=238, Percent_Identity=27.7310924369748, Blast_Score=70, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324857, Length=162, Percent_Identity=30.8641975308642, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24042; Mature: 24042

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLIRHGHSVGDDERRIKGSWDVELTPKGLKQAKLLKERLEKENYKCDLLFSSPLKRA
CCEEEEECCCCCCCCHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHH
AQTAEAVSQAVGKPIIYDSRLREQDSGKFAGMTREEASKFSPPPDEKGYRNYVPIPGGES
HHHHHHHHHHHCCCCEECHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHH
LLDHIRRVSEFYLELIDKHMDKRVCIVTHGGTINVLLRIIYNLPVNQPYVDKHIYLFAMN
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEC
DTAMSRLIIRGPQDVITYYLNNFSHLTAIK
HHHHHHHHHCCHHHHHHHHHHCCCHHEECC
>Mature Secondary Structure
MDLLLIRHGHSVGDDERRIKGSWDVELTPKGLKQAKLLKERLEKENYKCDLLFSSPLKRA
CCEEEEECCCCCCCCHHHCCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHH
AQTAEAVSQAVGKPIIYDSRLREQDSGKFAGMTREEASKFSPPPDEKGYRNYVPIPGGES
HHHHHHHHHHHCCCCEECHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHH
LLDHIRRVSEFYLELIDKHMDKRVCIVTHGGTINVLLRIIYNLPVNQPYVDKHIYLFAMN
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEC
DTAMSRLIIRGPQDVITYYLNNFSHLTAIK
HHHHHHHHHCCHHHHHHHHHHCCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320209 [H]