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The map label for this gene is yvqK [H]

Identifier: 239616851

GI number: 239616851

Start: 475543

End: 476067

Strand: Direct

Name: yvqK [H]

Synonym: Kole_0446

Alternate gene names: 239616851

Gene position: 475543-476067 (Clockwise)

Preceding gene: 239616850

Following gene: 239616854

Centisome position: 20.66

GC content: 37.71

Gene sequence:

>525_bases
ATGAGTATATCCACAGGTGGAGGAGATAAAGGTGAAACCAGCCTCTGGTCTGGCGAAAGGGTATCTAAAGATGATTTACG
TGTTGAAGCATACGGAACGATAGATGAATTGAATTCACATATCGGTGAAGCCAGGCATTACTGTAAATCAAAAGAAACCA
AGGAACTTCTTTTAAGAATTCAAAATGACCTTTTCAAAGTGGCGGGGCAACTGGCTTCTAAAGGTAAATTATTCATCGAA
CCAATAACTGAAACCGATGTTCAATGGCTAACAGAAAAAGTGCACCACTATGAAAAAATCATCAAATTAAAAGGTTTCGT
TATCTCGGGAACGACAATTCAATCTGCAAAATTAGATATATGCCGAACAGTAGCAAGAAGAGCAGAAAGAAGAATTGTCA
GTCTGTGTAAGACTGAAGAGATCGCCAATGAACTTTTGAAATATATGAACAGATTATCGGATTTCCTATTCATTTTGGCT
CGTTTTGAGGAGCACCTTGAAGGAAAACTTACATACAAAAGGTGA

Upstream 100 bases:

>100_bases
AAGGTTTAGAAAAGAGACGCACAACCCACAACTCTTTTTCTCGGATTCTCGGCTCTCGGTTCTCGAACTCTCGATTTTTG
GTTCCAAAGGAGGAATACCT

Downstream 100 bases:

>100_bases
AATACATACGTATCGGGTCCCAATATTTTTCAAACAGTCAGATTCTCATTTCTCTTCAATTTTCAAGGGACTGACTTTAT
TCTCAAGTGGAACATCTTCC

Product: ATP/cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSISTGGGDKGETSLWSGERVSKDDLRVEAYGTIDELNSHIGEARHYCKSKETKELLLRIQNDLFKVAGQLASKGKLFIE
PITETDVQWLTEKVHHYEKIIKLKGFVISGTTIQSAKLDICRTVARRAERRIVSLCKTEEIANELLKYMNRLSDFLFILA
RFEEHLEGKLTYKR

Sequences:

>Translated_174_residues
MSISTGGGDKGETSLWSGERVSKDDLRVEAYGTIDELNSHIGEARHYCKSKETKELLLRIQNDLFKVAGQLASKGKLFIE
PITETDVQWLTEKVHHYEKIIKLKGFVISGTTIQSAKLDICRTVARRAERRIVSLCKTEEIANELLKYMNRLSDFLFILA
RFEEHLEGKLTYKR
>Mature_173_residues
SISTGGGDKGETSLWSGERVSKDDLRVEAYGTIDELNSHIGEARHYCKSKETKELLLRIQNDLFKVAGQLASKGKLFIEP
ITETDVQWLTEKVHHYEKIIKLKGFVISGTTIQSAKLDICRTVARRAERRIVSLCKTEEIANELLKYMNRLSDFLFILAR
FEEHLEGKLTYKR

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=180, Percent_Identity=40, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI115534154, Length=167, Percent_Identity=35.9281437125749, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19934; Mature: 19803

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISTGGGDKGETSLWSGERVSKDDLRVEAYGTIDELNSHIGEARHYCKSKETKELLLRI
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
QNDLFKVAGQLASKGKLFIEPITETDVQWLTEKVHHYEKIIKLKGFVISGTTIQSAKLDI
HHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHH
CRTVARRAERRIVSLCKTEEIANELLKYMNRLSDFLFILARFEEHLEGKLTYKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SISTGGGDKGETSLWSGERVSKDDLRVEAYGTIDELNSHIGEARHYCKSKETKELLLRI
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
QNDLFKVAGQLASKGKLFIEPITETDVQWLTEKVHHYEKIIKLKGFVISGTTIQSAKLDI
HHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHH
CRTVARRAERRIVSLCKTEEIANELLKYMNRLSDFLFILARFEEHLEGKLTYKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]