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The map label for this gene is yjjG [H]

Identifier: 239616813

GI number: 239616813

Start: 428083

End: 428766

Strand: Direct

Name: yjjG [H]

Synonym: Kole_0406

Alternate gene names: 239616813

Gene position: 428083-428766 (Clockwise)

Preceding gene: 239616812

Following gene: 239616815

Centisome position: 18.6

GC content: 39.47

Gene sequence:

>684_bases
ATGAAATACGAAATAGTTTATTTCGACCTTGATGGTACCCTTCTCGATTTTGAGCGTTCAGAAGCTGAGGCTCTGACAGC
ACTCATGGCTAGCGGGGGATACTCTCTGAATGCCAAAGAACTTGCGCTTTATAAGGAAATCAACAAAAAGTGGTGGAAAG
CCCTGGCAGACGGAAAATACTCCAAAGAGTATATCGTTGTTGCCCGCTTTCAGGAGTTTTTTGAGACTATTGGATTCAAT
AAAATTACGCCTGAAGAAGCTTCAAAGTCTTACCTCATCGAACTTTCAAAACGCGCCTATTTTTTACCAGGAGCTGAAAA
ATTTTTGCTAAAACTCAAAAAAACTGGAAAAAGAATGGCAGCAATAACCAATGGCGTCGATTTAGTCCAAAAAAACAGAA
GCAAAATTGCTAATTTAGATAGGTTCTTTGAATTCATTTTAACTTCAGAAAAAGTAGGGAAAGCTAAACCGGCCCCGGAC
ATTTTCTTCGAAGCTGCTAAGATTTCCGGAGTACCGATAGACCGTTCTCTTTATGTCGGTGATAATCTGGAAACGGATTA
CGTTGGCGCCAAAAACGTCGGAATGGATTTTATCCTTTACGCACCAAAGGGAAAAGGAATATCGAAACTAAACGATCTAA
AAATCGCCAAAAGTTATGACGAACTGTTTGAAATGATTATGTGA

Upstream 100 bases:

>100_bases
ATCCCTTGGTGTCCCAGGTTCTTCCCTTTGAAAAAGCTTTAGAAGCTTTTGAACTGGCGAAAACCAAAGGGACACTTAAA
GTTATTCTAGAGGTGGAAAA

Downstream 100 bases:

>100_bases
GCTCCTTTTATACAGAATTTTTAAGCTTATAGGTATTTCAAAAGAGAAAATTCTCTTTCTTCAATGAATTTTCTGATGTC
TCTTATGGTGAATTCACCAG

Product: HAD-superfamily hydrolase, subfamily IA, variant 1

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKYEIVYFDLDGTLLDFERSEAEALTALMASGGYSLNAKELALYKEINKKWWKALADGKYSKEYIVVARFQEFFETIGFN
KITPEEASKSYLIELSKRAYFLPGAEKFLLKLKKTGKRMAAITNGVDLVQKNRSKIANLDRFFEFILTSEKVGKAKPAPD
IFFEAAKISGVPIDRSLYVGDNLETDYVGAKNVGMDFILYAPKGKGISKLNDLKIAKSYDELFEMIM

Sequences:

>Translated_227_residues
MKYEIVYFDLDGTLLDFERSEAEALTALMASGGYSLNAKELALYKEINKKWWKALADGKYSKEYIVVARFQEFFETIGFN
KITPEEASKSYLIELSKRAYFLPGAEKFLLKLKKTGKRMAAITNGVDLVQKNRSKIANLDRFFEFILTSEKVGKAKPAPD
IFFEAAKISGVPIDRSLYVGDNLETDYVGAKNVGMDFILYAPKGKGISKLNDLKIAKSYDELFEMIM
>Mature_227_residues
MKYEIVYFDLDGTLLDFERSEAEALTALMASGGYSLNAKELALYKEINKKWWKALADGKYSKEYIVVARFQEFFETIGFN
KITPEEASKSYLIELSKRAYFLPGAEKFLLKLKKTGKRMAAITNGVDLVQKNRSKIANLDRFFEFILTSEKVGKAKPAPD
IFFEAAKISGVPIDRSLYVGDNLETDYVGAKNVGMDFILYAPKGKGISKLNDLKIAKSYDELFEMIM

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Escherichia coli, GI1790833, Length=197, Percent_Identity=28.9340101522843, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 25719; Mature: 25719

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYEIVYFDLDGTLLDFERSEAEALTALMASGGYSLNAKELALYKEINKKWWKALADGKY
CCEEEEEEECCCEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
SKEYIVVARFQEFFETIGFNKITPEEASKSYLIELSKRAYFLPGAEKFLLKLKKTGKRMA
CCCEEEHHHHHHHHHHHCCCCCCHHHHCHHHEEEECCCEEECCCHHHHHHHHHHCCHHHH
AITNGVDLVQKNRSKIANLDRFFEFILTSEKVGKAKPAPDIFFEAAKISGVPIDRSLYVG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHHCCCCCCCEEEEC
DNLETDYVGAKNVGMDFILYAPKGKGISKLNDLKIAKSYDELFEMIM
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKYEIVYFDLDGTLLDFERSEAEALTALMASGGYSLNAKELALYKEINKKWWKALADGKY
CCEEEEEEECCCEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
SKEYIVVARFQEFFETIGFNKITPEEASKSYLIELSKRAYFLPGAEKFLLKLKKTGKRMA
CCCEEEHHHHHHHHHHHCCCCCCHHHHCHHHEEEECCCEEECCCHHHHHHHHHHCCHHHH
AITNGVDLVQKNRSKIANLDRFFEFILTSEKVGKAKPAPDIFFEAAKISGVPIDRSLYVG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHHCCCCCCCEEEEC
DNLETDYVGAKNVGMDFILYAPKGKGISKLNDLKIAKSYDELFEMIM
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]