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The map label for this gene is hemN [H]

Identifier: 239616730

GI number: 239616730

Start: 342925

End: 344073

Strand: Reverse

Name: hemN [H]

Synonym: Kole_0323

Alternate gene names: 239616730

Gene position: 344073-342925 (Counterclockwise)

Preceding gene: 239616731

Following gene: 239616729

Centisome position: 14.95

GC content: 40.64

Gene sequence:

>1149_bases
ATGAAAGAGGTTGGAATATACATACATCTCCCCTTTTGCAAAAGGAAATGCGATTACTGCGATTTTTTGACACTGCCGTT
TGATGCAGATCAAGCGGAGACCTATAATAAAGCCTTGTTAAGCGAAATAGAGTTGTGGACTTCTAACAATGAATTAATGC
TAAAAACCCTGTACTTTGGCGGTGGGTCCCCCTCATTGTATCAGCCTCGTTTTCTCGAGAAACTTATCGATAGACTCGCT
TTCTCTTCACAGTTTCAGGTAGAAGAATTGACTCTTGAAGCCAATCCATGGGAGATAACTTGCGAAAATCTGAGAGACTG
GAAGGAGCTTGGTGTAAACAGATTGAGCATCGGAATACAGACAGCGCCAACAGAAGTACTCAACAACGTTGGCCGAAAAA
ATCCAGTAGATTTGCTCAGAAGATTAGGGTTTGCGCGGGAAGCCTTTGATAACGTAAATTTTGACTTTATTTTAGGGCTT
CCAGGTGAGAGCCGCGAAACCTTTGAGAATAATATAAAACTCATAGAAAGGTTCCTACCTGAACATATTTCCTATTATAT
CCTCGATACCGACCATGACACTCCTTTGATGAGAAGAGTTTTAACTGGTAAAATTGAGCTGCCGAGCGTAGATTTGATAA
CGGAACTACATGAACATCTTATCAAAACCCTTGAAGAGAAGGGATATAATCGTTACGAAATCTCTTCGTGGTCAAGGGAA
GGTTACCAGTGTATACACAACAAAAACTACTGGGAAAACGGGGAATACGTCGGCTTGGGGATTTCTGCAGGTGGTCATTT
CAATCGATTTAGATATGTCAACACAACTTCATTTTCGGAGTATGTGAAGGCAATGAATGTTGGACACTTTGCAAGAGAGT
ACGAACATCAAAACAATGATTTAGAGGAACTTTTCGAAACCCTTTTTATGGGGCTCAGGCTTGTTGAAGGTGTCAGAATC
AGCAGATTCCAGGTGAATGAGTCATTGCTGGAGAAAGTGGTAGAGAGAATAGAAAAAAGTTTGGAAGGTTTTGTTATAGT
GGATAATGAAAGGATCAAACTCAACGATAGGGGTCTTGATCTTTCGAAAGTTGTGTTTGAAAGACTGATGGGGATAAAGG
AGGAGATTGAAGATGTTTTCACCTCATGA

Upstream 100 bases:

>100_bases
ATCTCCTCGTCAGCAATCTTGGTAATCGTGAGCTGTTTGCTTTGGGGATCGGTTTGAATAATTTAGATGTTGTCACGATG
TTCGTGAGGTTCATTTATTA

Downstream 100 bases:

>100_bases
GATACTGGAGATTGCTTTGAATATTGAGGTTGAGGGTTACAAGTTTTATATGACCATGGCGAAAAACAGTAATAGAGAAG
ATGCAAAATCCACTTTTCAA

Product: oxygen-independent coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKEVGIYIHLPFCKRKCDYCDFLTLPFDADQAETYNKALLSEIELWTSNNELMLKTLYFGGGSPSLYQPRFLEKLIDRLA
FSSQFQVEELTLEANPWEITCENLRDWKELGVNRLSIGIQTAPTEVLNNVGRKNPVDLLRRLGFAREAFDNVNFDFILGL
PGESRETFENNIKLIERFLPEHISYYILDTDHDTPLMRRVLTGKIELPSVDLITELHEHLIKTLEEKGYNRYEISSWSRE
GYQCIHNKNYWENGEYVGLGISAGGHFNRFRYVNTTSFSEYVKAMNVGHFAREYEHQNNDLEELFETLFMGLRLVEGVRI
SRFQVNESLLEKVVERIEKSLEGFVIVDNERIKLNDRGLDLSKVVFERLMGIKEEIEDVFTS

Sequences:

>Translated_382_residues
MKEVGIYIHLPFCKRKCDYCDFLTLPFDADQAETYNKALLSEIELWTSNNELMLKTLYFGGGSPSLYQPRFLEKLIDRLA
FSSQFQVEELTLEANPWEITCENLRDWKELGVNRLSIGIQTAPTEVLNNVGRKNPVDLLRRLGFAREAFDNVNFDFILGL
PGESRETFENNIKLIERFLPEHISYYILDTDHDTPLMRRVLTGKIELPSVDLITELHEHLIKTLEEKGYNRYEISSWSRE
GYQCIHNKNYWENGEYVGLGISAGGHFNRFRYVNTTSFSEYVKAMNVGHFAREYEHQNNDLEELFETLFMGLRLVEGVRI
SRFQVNESLLEKVVERIEKSLEGFVIVDNERIKLNDRGLDLSKVVFERLMGIKEEIEDVFTS
>Mature_382_residues
MKEVGIYIHLPFCKRKCDYCDFLTLPFDADQAETYNKALLSEIELWTSNNELMLKTLYFGGGSPSLYQPRFLEKLIDRLA
FSSQFQVEELTLEANPWEITCENLRDWKELGVNRLSIGIQTAPTEVLNNVGRKNPVDLLRRLGFAREAFDNVNFDFILGL
PGESRETFENNIKLIERFLPEHISYYILDTDHDTPLMRRVLTGKIELPSVDLITELHEHLIKTLEEKGYNRYEISSWSRE
GYQCIHNKNYWENGEYVGLGISAGGHFNRFRYVNTTSFSEYVKAMNVGHFAREYEHQNNDLEELFETLFMGLRLVEGVRI
SRFQVNESLLEKVVERIEKSLEGFVIVDNERIKLNDRGLDLSKVVFERLMGIKEEIEDVFTS

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=271, Percent_Identity=31.7343173431734, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1789325, Length=346, Percent_Identity=29.7687861271676, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87082341, Length=306, Percent_Identity=25.1633986928105, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 44601; Mature: 44601

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVGIYIHLPFCKRKCDYCDFLTLPFDADQAETYNKALLSEIELWTSNNELMLKTLYFG
CCCEEEEEECCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEECCCCEEEEEEEEC
GGSPSLYQPRFLEKLIDRLAFSSQFQVEELTLEANPWEITCENLRDWKELGVNRLSIGIQ
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEHHHHHHHHHCCCCEEEEECC
TAPTEVLNNVGRKNPVDLLRRLGFAREAFDNVNFDFILGLPGESRETFENNIKLIERFLP
CCHHHHHHHCCCCCHHHHHHHHCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
EHISYYILDTDHDTPLMRRVLTGKIELPSVDLITELHEHLIKTLEEKGYNRYEISSWSRE
HHCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHH
GYQCIHNKNYWENGEYVGLGISAGGHFNRFRYVNTTSFSEYVKAMNVGHFAREYEHQNND
HHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
LEELFETLFMGLRLVEGVRISRFQVNESLLEKVVERIEKSLEGFVIVDNERIKLNDRGLD
HHHHHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCC
LSKVVFERLMGIKEEIEDVFTS
HHHHHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure
MKEVGIYIHLPFCKRKCDYCDFLTLPFDADQAETYNKALLSEIELWTSNNELMLKTLYFG
CCCEEEEEECCHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEECCCCEEEEEEEEC
GGSPSLYQPRFLEKLIDRLAFSSQFQVEELTLEANPWEITCENLRDWKELGVNRLSIGIQ
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEHHHHHHHHHCCCCEEEEECC
TAPTEVLNNVGRKNPVDLLRRLGFAREAFDNVNFDFILGLPGESRETFENNIKLIERFLP
CCHHHHHHHCCCCCHHHHHHHHCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
EHISYYILDTDHDTPLMRRVLTGKIELPSVDLITELHEHLIKTLEEKGYNRYEISSWSRE
HHCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCHH
GYQCIHNKNYWENGEYVGLGISAGGHFNRFRYVNTTSFSEYVKAMNVGHFAREYEHQNND
HHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
LEELFETLFMGLRLVEGVRISRFQVNESLLEKVVERIEKSLEGFVIVDNERIKLNDRGLD
HHHHHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCC
LSKVVFERLMGIKEEIEDVFTS
HHHHHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]