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The map label for this gene is oxaA [H]

Identifier: 239616662

GI number: 239616662

Start: 282953

End: 284290

Strand: Reverse

Name: oxaA [H]

Synonym: Kole_0255

Alternate gene names: 239616662

Gene position: 284290-282953 (Counterclockwise)

Preceding gene: 239616663

Following gene: 239616661

Centisome position: 12.35

GC content: 39.91

Gene sequence:

>1338_bases
ATGAGAAAAATTACTGCTTTGTTCTTTATCTTGGTTGTTTTGTTTGCTTCTGTTCTCCTTGGTTCTGAAATGACCACAAA
AGAGGGGACAGACACTCTCACGATATCTTCCAAGACTTTTACAATTGTTCTAAATACCAGGTTGGGGGTTCTTGACGATA
TTCGTATTAACGTGGATAGAAAGGTTGTAGATATTTATACTTATTATCCTGAAGATCCTGATGGTTACAATGTGTACGGT
TCCAACGGCGAACTCATTCCAATTTCATTCTCATACGAAGAGGATGAAAATGGAAATATTCTTGTCTACTTTTTCTATGA
TAGTGGAACAAAAACCTTTGTCGTAAAAAATGACCCTTACTACGATTTTGATATTATTCTATCTTTTTCAGAGGAGATTA
CCGCTGTAAGTGTTCCTTATATATCGGAGATAAATCAGAAAGTCCATCCGAACTTCTTCATTACATATGCAAAACCTGAT
AAACAGAAAACGGTGTGCATTAGTTATTCTGAAGAAGGACGTTTTGACGTAAAACGTTTTTATCCCAACTCCGGAAGAGC
AACTATCTCTGCCTTTGCCGGGCCTGTCAAACTCATACATATCTCCGAAGCGTTTCCGGAGATATACGAAGAAATAAAAA
AGGACCTCGAGGAATTCGGTGCCATCGGTTTTACAAGCTATATATTCCACGGGCTTGTCGCATTTCTTTACTGGCTCTAT
AAGCTGACGAAGAGCTTTGGTTGGGCTATCATCCTGTTCACCATCGTTGTAAGGCTGGTCCTCTATCCCCTTTATCATCT
CCAGACGAAATCAATGATACAGATGCGTGCGGTACAACCTGAAATAGAAAAAATCAAAAAGAAGTACAAGGATCCTCAAA
AGCAGCAACAGGCTCTTACAAAGCTTTACCGGGAAAAGAACATAAATCCTGCAACCGGTTGTCTCACTCTTTTGATACAG
CTACCGGTGTTTTTTGTATTGTACGCTGTTATCCGTTACTTCGGCGAGATGTTTGCTTATTCGCCGAAGTTCCTGATCTG
GAGCGATCTTTCAACCGGCGGATTCGTTATAAACCTGCCATTTATAATCATCACAATCCTTGCGGGATTTTACATGTCGC
TATTTACAAGCCAGGATCCACGGGCAGCCAGACAGGGCATGATTTTTAATGTAATGTTTCCGTTCCTTTTTTACAGTTTC
CCATCGGGTTTATTCCTTTACTACACCACAAATACTGTCATACAGATGCTCATTACTATTTACGTCTACCGTAAATTTGG
CATCAAAAAACTAACAGTCAGGGAAGTTCTGGGATTGCCACCAAAACCCGTGAAATAA

Upstream 100 bases:

>100_bases
TTTTGCTGGGAACCTGGCGTATTTTAAGATGCAACCCCTTCAACAAAGGTGGATATGATCCAGTTCCAGAAGAATTCAAA
CTGCTAAGGAGGAACACGAA

Downstream 100 bases:

>100_bases
CGCTATGTTAAAGTTCTGGGAGGTGTACATTTAAATGAAAACCGTCGTAGTAAGTGCTCCATCAGTGGATGAAGCAGTAA
GACTCGCTCAGATTAAGCTC

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MRKITALFFILVVLFASVLLGSEMTTKEGTDTLTISSKTFTIVLNTRLGVLDDIRINVDRKVVDIYTYYPEDPDGYNVYG
SNGELIPISFSYEEDENGNILVYFFYDSGTKTFVVKNDPYYDFDIILSFSEEITAVSVPYISEINQKVHPNFFITYAKPD
KQKTVCISYSEEGRFDVKRFYPNSGRATISAFAGPVKLIHISEAFPEIYEEIKKDLEEFGAIGFTSYIFHGLVAFLYWLY
KLTKSFGWAIILFTIVVRLVLYPLYHLQTKSMIQMRAVQPEIEKIKKKYKDPQKQQQALTKLYREKNINPATGCLTLLIQ
LPVFFVLYAVIRYFGEMFAYSPKFLIWSDLSTGGFVINLPFIIITILAGFYMSLFTSQDPRAARQGMIFNVMFPFLFYSF
PSGLFLYYTTNTVIQMLITIYVYRKFGIKKLTVREVLGLPPKPVK

Sequences:

>Translated_445_residues
MRKITALFFILVVLFASVLLGSEMTTKEGTDTLTISSKTFTIVLNTRLGVLDDIRINVDRKVVDIYTYYPEDPDGYNVYG
SNGELIPISFSYEEDENGNILVYFFYDSGTKTFVVKNDPYYDFDIILSFSEEITAVSVPYISEINQKVHPNFFITYAKPD
KQKTVCISYSEEGRFDVKRFYPNSGRATISAFAGPVKLIHISEAFPEIYEEIKKDLEEFGAIGFTSYIFHGLVAFLYWLY
KLTKSFGWAIILFTIVVRLVLYPLYHLQTKSMIQMRAVQPEIEKIKKKYKDPQKQQQALTKLYREKNINPATGCLTLLIQ
LPVFFVLYAVIRYFGEMFAYSPKFLIWSDLSTGGFVINLPFIIITILAGFYMSLFTSQDPRAARQGMIFNVMFPFLFYSF
PSGLFLYYTTNTVIQMLITIYVYRKFGIKKLTVREVLGLPPKPVK
>Mature_445_residues
MRKITALFFILVVLFASVLLGSEMTTKEGTDTLTISSKTFTIVLNTRLGVLDDIRINVDRKVVDIYTYYPEDPDGYNVYG
SNGELIPISFSYEEDENGNILVYFFYDSGTKTFVVKNDPYYDFDIILSFSEEITAVSVPYISEINQKVHPNFFITYAKPD
KQKTVCISYSEEGRFDVKRFYPNSGRATISAFAGPVKLIHISEAFPEIYEEIKKDLEEFGAIGFTSYIFHGLVAFLYWLY
KLTKSFGWAIILFTIVVRLVLYPLYHLQTKSMIQMRAVQPEIEKIKKKYKDPQKQQQALTKLYREKNINPATGCLTLLIQ
LPVFFVLYAVIRYFGEMFAYSPKFLIWSDLSTGGFVINLPFIIITILAGFYMSLFTSQDPRAARQGMIFNVMFPFLFYSF
PSGLFLYYTTNTVIQMLITIYVYRKFGIKKLTVREVLGLPPKPVK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=221, Percent_Identity=32.1266968325792, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 51341; Mature: 51341

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKITALFFILVVLFASVLLGSEMTTKEGTDTLTISSKTFTIVLNTRLGVLDDIRINVDR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEEECCCCCEECEEEECCC
KVVDIYTYYPEDPDGYNVYGSNGELIPISFSYEEDENGNILVYFFYDSGTKTFVVKNDPY
EEEEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCC
YDFDIILSFSEEITAVSVPYISEINQKVHPNFFITYAKPDKQKTVCISYSEEGRFDVKRF
CCEEEEEECCCCCEEEECHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEEHEEE
YPNSGRATISAFAGPVKLIHISEAFPEIYEEIKKDLEEFGAIGFTSYIFHGLVAFLYWLY
CCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KLTKSFGWAIILFTIVVRLVLYPLYHLQTKSMIQMRAVQPEIEKIKKKYKDPQKQQQALT
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
KLYREKNINPATGCLTLLIQLPVFFVLYAVIRYFGEMFAYSPKFLIWSDLSTGGFVINLP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHH
FIIITILAGFYMSLFTSQDPRAARQGMIFNVMFPFLFYSFPSGLFLYYTTNTVIQMLITI
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
YVYRKFGIKKLTVREVLGLPPKPVK
HHHHHCCCCCEEHHHHHCCCCCCCC
>Mature Secondary Structure
MRKITALFFILVVLFASVLLGSEMTTKEGTDTLTISSKTFTIVLNTRLGVLDDIRINVDR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEEECCCCCEECEEEECCC
KVVDIYTYYPEDPDGYNVYGSNGELIPISFSYEEDENGNILVYFFYDSGTKTFVVKNDPY
EEEEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCC
YDFDIILSFSEEITAVSVPYISEINQKVHPNFFITYAKPDKQKTVCISYSEEGRFDVKRF
CCEEEEEECCCCCEEEECHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEEHEEE
YPNSGRATISAFAGPVKLIHISEAFPEIYEEIKKDLEEFGAIGFTSYIFHGLVAFLYWLY
CCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KLTKSFGWAIILFTIVVRLVLYPLYHLQTKSMIQMRAVQPEIEKIKKKYKDPQKQQQALT
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHH
KLYREKNINPATGCLTLLIQLPVFFVLYAVIRYFGEMFAYSPKFLIWSDLSTGGFVINLP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHH
FIIITILAGFYMSLFTSQDPRAARQGMIFNVMFPFLFYSFPSGLFLYYTTNTVIQMLITI
HHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
YVYRKFGIKKLTVREVLGLPPKPVK
HHHHHCCCCCEEHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]