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The map label for this gene is yabD [H]

Identifier: 239616635

GI number: 239616635

Start: 256637

End: 257458

Strand: Reverse

Name: yabD [H]

Synonym: Kole_0228

Alternate gene names: 239616635

Gene position: 257458-256637 (Counterclockwise)

Preceding gene: 239616636

Following gene: 239616634

Centisome position: 11.18

GC content: 45.86

Gene sequence:

>822_bases
ATGAGATCATACATGACGGAGACATCGTACACATCAGGGCAAACGCGTGAGCTCAAAATCTGCGATACGCACGCCCATCT
GAATTTTCCCCATTTCAACAGAGACCGGAAACGAATCCTTGAAGAGATAGATTCAGGAAAGATTGTTTTTACCATAGAAG
TGGGTACGAATATGGACGATTCCAAAGCAGCAGTCGAACTTGCGAAAGCCAACCGTCATATCTTTGCATCTGTTGGGGTT
CATCCGCATGATAGTGATGAAGTGCCTTCTGATTACATAGATATACTGAAGGAATTGGCTGCTGAAAAGAAGGTAGTGGC
CTTAGGCGAGATCGGCCTGGATTTTTATCGGGATTTATCGCCCAAAGATGTTCAGAGGAAGGTTTTTCGCGAACAGCTTT
TGCTTGCACAGGAACTTGATATGCCGGTGATCGTTCACGTCAGGGATGCTTATTACGATGCCTATGAAATATTGAGAGAG
TTCGAAGGAAAACTCACAGGCGTTATCCATGCCTTTTCAGGCACGCAGGAAGACGCGCTCAGATTCAAAGAACTTGGATT
TAAGCTCGGCATAGGGGGACCGCTAACCTATCCAAAAAACAAAGGACTCAGAGAGATTGTAAAGGTTTTGCCGATAGAGA
CCTTTGTACCGGAAACGGACTGTCCCTACCTTCCGCCGCAGCCGCACAGGGGAAAGAGAAATGAACCGTATTATGTCCGT
TTTGTTGTGGAAAAGATTTCCGAGTTGAAGGGTCTTTCAGTTGAGACCTGTGCTGATATTCTTTGCGCAAATGCGGTCGC
TCTTTTCAGACTGAACCTTTAG

Upstream 100 bases:

>100_bases
AACTTCATCCGTGCGGAGGTCATTCCCTACCAGACCTTCATAGAGATTGGAGATATGCACGAAGCCAAAAATAAGGGGCT
TGTTAAACTCGTAGGAAGGG

Downstream 100 bases:

>100_bases
AGGGGGTTGCTTCGTGGGTGAGATTGAGAAGTTCAGGAAATTTAGGAAAAAAATGAACAAAAGGATCCTGGAGACGGGCG
ATATAAACACGAAGAGATTC

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRSYMTETSYTSGQTRELKICDTHAHLNFPHFNRDRKRILEEIDSGKIVFTIEVGTNMDDSKAAVELAKANRHIFASVGV
HPHDSDEVPSDYIDILKELAAEKKVVALGEIGLDFYRDLSPKDVQRKVFREQLLLAQELDMPVIVHVRDAYYDAYEILRE
FEGKLTGVIHAFSGTQEDALRFKELGFKLGIGGPLTYPKNKGLREIVKVLPIETFVPETDCPYLPPQPHRGKRNEPYYVR
FVVEKISELKGLSVETCADILCANAVALFRLNL

Sequences:

>Translated_273_residues
MRSYMTETSYTSGQTRELKICDTHAHLNFPHFNRDRKRILEEIDSGKIVFTIEVGTNMDDSKAAVELAKANRHIFASVGV
HPHDSDEVPSDYIDILKELAAEKKVVALGEIGLDFYRDLSPKDVQRKVFREQLLLAQELDMPVIVHVRDAYYDAYEILRE
FEGKLTGVIHAFSGTQEDALRFKELGFKLGIGGPLTYPKNKGLREIVKVLPIETFVPETDCPYLPPQPHRGKRNEPYYVR
FVVEKISELKGLSVETCADILCANAVALFRLNL
>Mature_273_residues
MRSYMTETSYTSGQTRELKICDTHAHLNFPHFNRDRKRILEEIDSGKIVFTIEVGTNMDDSKAAVELAKANRHIFASVGV
HPHDSDEVPSDYIDILKELAAEKKVVALGEIGLDFYRDLSPKDVQRKVFREQLLLAQELDMPVIVHVRDAYYDAYEILRE
FEGKLTGVIHAFSGTQEDALRFKELGFKLGIGGPLTYPKNKGLREIVKVLPIETFVPETDCPYLPPQPHRGKRNEPYYVR
FVVEKISELKGLSVETCADILCANAVALFRLNL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903439, Length=246, Percent_Identity=30.8943089430894, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI14042943, Length=258, Percent_Identity=30.6201550387597, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI110349730, Length=263, Percent_Identity=30.0380228136882, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=30.0380228136882, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=30, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=29.0196078431373, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI225903424, Length=159, Percent_Identity=32.0754716981132, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=36.2934362934363, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI48994985, Length=256, Percent_Identity=33.59375, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=31.3725490196078, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17559024, Length=283, Percent_Identity=30.3886925795053, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=208, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=29.7202797202797, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221330018, Length=297, Percent_Identity=29.96632996633, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586117, Length=247, Percent_Identity=31.9838056680162, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 31025; Mature: 31025

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSYMTETSYTSGQTRELKICDTHAHLNFPHFNRDRKRILEEIDSGKIVFTIEVGTNMDD
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
SKAAVELAKANRHIFASVGVHPHDSDEVPSDYIDILKELAAEKKVVALGEIGLDFYRDLS
HHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHCHHHHHCCC
PKDVQRKVFREQLLLAQELDMPVIVHVRDAYYDAYEILREFEGKLTGVIHAFSGTQEDAL
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHEEEEEECCCCHHHHH
RFKELGFKLGIGGPLTYPKNKGLREIVKVLPIETFVPETDCPYLPPQPHRGKRNEPYYVR
HHHHCCEEECCCCCCCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCEEEH
FVVEKISELKGLSVETCADILCANAVALFRLNL
HHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MRSYMTETSYTSGQTRELKICDTHAHLNFPHFNRDRKRILEEIDSGKIVFTIEVGTNMDD
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
SKAAVELAKANRHIFASVGVHPHDSDEVPSDYIDILKELAAEKKVVALGEIGLDFYRDLS
HHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHCHHHHHCCC
PKDVQRKVFREQLLLAQELDMPVIVHVRDAYYDAYEILREFEGKLTGVIHAFSGTQEDAL
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCHHEEEEEECCCCHHHHH
RFKELGFKLGIGGPLTYPKNKGLREIVKVLPIETFVPETDCPYLPPQPHRGKRNEPYYVR
HHHHCCEEECCCCCCCCCCCCCHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCEEEH
FVVEKISELKGLSVETCADILCANAVALFRLNL
HHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]