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The map label for this gene is coaE [H]

Identifier: 239616584

GI number: 239616584

Start: 199356

End: 199937

Strand: Reverse

Name: coaE [H]

Synonym: Kole_0176

Alternate gene names: 239616584

Gene position: 199937-199356 (Counterclockwise)

Preceding gene: 239616585

Following gene: 239616583

Centisome position: 8.68

GC content: 41.92

Gene sequence:

>582_bases
ATGAAAATCATAGGCGTTACGGGAAAAGCCGGCTGCGGGAAGTCTTTGCTTGTTTCACTTCTTTCCGGTCCTGAAACAAA
GGTGATAGATCTCGACAGATTGGGCCACGAGGTTCTCAAGGAGCTCAAAAGCCAGCTTGTACTTACGTACGGTTCCGGGA
TACTGGATAACAGCAGAAAGAAGATCGATAGAAAAAAACTCGGTGAAATAGTCTTCAAAGATTCTCGAAAACTCAAGCTT
CTCAACAGTATTGTGCATCCACTAATAAAAGAAAAAGTGAAAAAGATCATTTCAAAAACCAGGAAGAAATACGTACTGAT
CGATGGAGCGTTGATCCATCAGATCGGATTGGGCAAATTATGCGATCTGATCATCTGGGTTGATTGCCCTGATGAGGTTG
CAATTAAGAGACTCGCTAGCAGAGGGATACCTCGCGAACGCGCTATCAGTATTCTTAATTCGCAGAAAGAGCTGGAAAAT
TATAAAGTATACTCAGACATAGCGATAGACAATACTGGTTCGCCTCAAGAGCTCTTAATCAAGGTTAGGGAAATTTTGCG
GGGAAAAGAAATAATGCTATAA

Upstream 100 bases:

>100_bases
TCGTTCTGTCGCCGGAAGAGAAAGAGGCAATCGGTTCAACGAACAGCGAAATAGCAGCGGCCGTTTCAAAAGCCATAGAA
AAGGGGCAGAAGGTACTCTG

Downstream 100 bases:

>100_bases
TAGTTGGCGCAATGCCACTTCAACAAAGGAGGTAAGGGGTATGAAAAAGCTACTTCTTGTCATTACCATGGTACTTGCAT
TGTCCATTTTTGCCATGGCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKIIGVTGKAGCGKSLLVSLLSGPETKVIDLDRLGHEVLKELKSQLVLTYGSGILDNSRKKIDRKKLGEIVFKDSRKLKL
LNSIVHPLIKEKVKKIISKTRKKYVLIDGALIHQIGLGKLCDLIIWVDCPDEVAIKRLASRGIPRERAISILNSQKELEN
YKVYSDIAIDNTGSPQELLIKVREILRGKEIML

Sequences:

>Translated_193_residues
MKIIGVTGKAGCGKSLLVSLLSGPETKVIDLDRLGHEVLKELKSQLVLTYGSGILDNSRKKIDRKKLGEIVFKDSRKLKL
LNSIVHPLIKEKVKKIISKTRKKYVLIDGALIHQIGLGKLCDLIIWVDCPDEVAIKRLASRGIPRERAISILNSQKELEN
YKVYSDIAIDNTGSPQELLIKVREILRGKEIML
>Mature_193_residues
MKIIGVTGKAGCGKSLLVSLLSGPETKVIDLDRLGHEVLKELKSQLVLTYGSGILDNSRKKIDRKKLGEIVFKDSRKLKL
LNSIVHPLIKEKVKKIISKTRKKYVLIDGALIHQIGLGKLCDLIIWVDCPDEVAIKRLASRGIPRERAISILNSQKELEN
YKVYSDIAIDNTGSPQELLIKVREILRGKEIML

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI110227607, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI205277394, Length=163, Percent_Identity=31.2883435582822, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI110227605, Length=163, Percent_Identity=31.2883435582822, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI110227603, Length=163, Percent_Identity=31.2883435582822, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI110227601, Length=163, Percent_Identity=31.2883435582822, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI1786292, Length=177, Percent_Identity=27.683615819209, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=29.8969072164948, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658602, Length=173, Percent_Identity=28.9017341040462, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=29.1891891891892, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21602; Mature: 21602

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIGVTGKAGCGKSLLVSLLSGPETKVIDLDRLGHEVLKELKSQLVLTYGSGILDNSRK
CEEEECCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHEEHHHCCCCCCCHHH
KIDRKKLGEIVFKDSRKLKLLNSIVHPLIKEKVKKIISKTRKKYVLIDGALIHQIGLGKL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHCHHHH
CDLIIWVDCPDEVAIKRLASRGIPRERAISILNSQKELENYKVYSDIAIDNTGSPQELLI
HHEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHH
KVREILRGKEIML
HHHHHHCCCCCCC
>Mature Secondary Structure
MKIIGVTGKAGCGKSLLVSLLSGPETKVIDLDRLGHEVLKELKSQLVLTYGSGILDNSRK
CEEEECCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHEEHHHCCCCCCCHHH
KIDRKKLGEIVFKDSRKLKLLNSIVHPLIKEKVKKIISKTRKKYVLIDGALIHQIGLGKL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECHHHHHHHCHHHH
CDLIIWVDCPDEVAIKRLASRGIPRERAISILNSQKELENYKVYSDIAIDNTGSPQELLI
HHEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHH
KVREILRGKEIML
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]