Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 239616512

GI number: 239616512

Start: 117934

End: 119034

Strand: Reverse

Name: argD [H]

Synonym: Kole_0102

Alternate gene names: 239616512

Gene position: 119034-117934 (Counterclockwise)

Preceding gene: 239616513

Following gene: 239616510

Centisome position: 5.17

GC content: 45.87

Gene sequence:

>1101_bases
ATGCTGTGCAAGGTATATACACCATATGAATTTAAGGTTGAGAAGGCCCGGGGAATAGAGATATTCACAGACAAGGGTGT
ATTTCTCGACACCTATTCCGGAATCGGAGTTCTGGCTCTTGGACATTCAAATCCCGAAGTACTGACCGCAATGAAGAAAA
AGCTGGAAAGATACACTCATCTGTCAAATTACTTCCTTGACGAAGATGCAGAAGAAGTGGCTGCGAGGTTGGTTGGCCTG
TCAGGCCAGGTTGGAGAGGTTTTCTTCACCAATTCGGGTACAGAAGCTACCGAGGCTGCCTTAAAGGCAATCAAAAAACT
CCGTAAGGGTAAGATAGTGAGCTTTGTGGGAAACTTTCACGGACGTACCATCGGTGCCCTATCGCTGACCTATGGCAAAG
CAATACGCGAACCCTTCGAACCCCTGCTGACTGAAAGAGTTTTTCTGAAGCCGGACCCTGAGAAATTTACTAGCTTTGCC
AGAGAAAACCAGATAGCCGGAGTCTTTATCGAGTGCATACAGGGAAACAGCGGTGTATTACCACTGTCTGAAGAACTTCT
GGAAACCATTTCACAGTATCAAAGGGAGCAGGGTTTTATTCTTGTGGCAGATGAAATACAGTCCGGTCTGGGCAGGACAG
GAAAAGCTTTCGCTTATCAACATTTTGGACTGAAGCCCGATATAATAACCGTAGGCAAAGCACTTGGTGGTGGTCTGCCC
CTTGGTGCAGCTCTTTTCTCTGGATTCAGCCCCTTTAAATTCGGTGAACATGGCTCCACCTTTGCCCCGAACCCCGTTGC
ACTTGCCGCGGGAAAGATAGTTTTATCGAAATTAGACGAGAATTTTCTCATGCAGGTCCAGGAAAAGGGAAAATATTTTA
GAGAAAAACTGGCTGAATTGCCATGGGTCCAGTCTGTAAATGGCTATGGTCTCATGATCGGTGTTACCACCGAAAACGCT
TCAAAGGTAAAGGCTGAAGCCTATAATAGAGGCGTGCTATTGAACATAGCTGGAGGCAGAATTCGCTTCCTGCCAGCACT
CAATATAACCATAGACGAGATAGATGAAATAATAAGCAGGCTTAGTTTTGAAGGTTTTTGA

Upstream 100 bases:

>100_bases
CTACTTCCGAGATAAAGATTTCGGTGCTTGTTCCAAAGGAAGAATCGGGAAGAGCTTTGAAGGCTCTGATAGATGAGTTT
GAGCTTTGAGGGTGGTTCGT

Downstream 100 bases:

>100_bases
ATTTTCAAAGTCTGCATATTGTTTATGATTTTTTAGTATTTTTCACCCAACAATAATGGATTACCGTACCTCTTCAAATT
TATCTTTTCCGACACCGCAT

Product: aminotransferase class-III

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLCKVYTPYEFKVEKARGIEIFTDKGVFLDTYSGIGVLALGHSNPEVLTAMKKKLERYTHLSNYFLDEDAEEVAARLVGL
SGQVGEVFFTNSGTEATEAALKAIKKLRKGKIVSFVGNFHGRTIGALSLTYGKAIREPFEPLLTERVFLKPDPEKFTSFA
RENQIAGVFIECIQGNSGVLPLSEELLETISQYQREQGFILVADEIQSGLGRTGKAFAYQHFGLKPDIITVGKALGGGLP
LGAALFSGFSPFKFGEHGSTFAPNPVALAAGKIVLSKLDENFLMQVQEKGKYFREKLAELPWVQSVNGYGLMIGVTTENA
SKVKAEAYNRGVLLNIAGGRIRFLPALNITIDEIDEIISRLSFEGF

Sequences:

>Translated_366_residues
MLCKVYTPYEFKVEKARGIEIFTDKGVFLDTYSGIGVLALGHSNPEVLTAMKKKLERYTHLSNYFLDEDAEEVAARLVGL
SGQVGEVFFTNSGTEATEAALKAIKKLRKGKIVSFVGNFHGRTIGALSLTYGKAIREPFEPLLTERVFLKPDPEKFTSFA
RENQIAGVFIECIQGNSGVLPLSEELLETISQYQREQGFILVADEIQSGLGRTGKAFAYQHFGLKPDIITVGKALGGGLP
LGAALFSGFSPFKFGEHGSTFAPNPVALAAGKIVLSKLDENFLMQVQEKGKYFREKLAELPWVQSVNGYGLMIGVTTENA
SKVKAEAYNRGVLLNIAGGRIRFLPALNITIDEIDEIISRLSFEGF
>Mature_366_residues
MLCKVYTPYEFKVEKARGIEIFTDKGVFLDTYSGIGVLALGHSNPEVLTAMKKKLERYTHLSNYFLDEDAEEVAARLVGL
SGQVGEVFFTNSGTEATEAALKAIKKLRKGKIVSFVGNFHGRTIGALSLTYGKAIREPFEPLLTERVFLKPDPEKFTSFA
RENQIAGVFIECIQGNSGVLPLSEELLETISQYQREQGFILVADEIQSGLGRTGKAFAYQHFGLKPDIITVGKALGGGLP
LGAALFSGFSPFKFGEHGSTFAPNPVALAAGKIVLSKLDENFLMQVQEKGKYFREKLAELPWVQSVNGYGLMIGVTTENA
SKVKAEAYNRGVLLNIAGGRIRFLPALNITIDEIDEIISRLSFEGF

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=382, Percent_Identity=30.6282722513089, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI13994255, Length=394, Percent_Identity=30.7106598984772, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI284507298, Length=290, Percent_Identity=32.7586206896552, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=24.7058823529412, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI24119277, Length=426, Percent_Identity=25.8215962441315, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=24.8704663212435, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI188536080, Length=411, Percent_Identity=24.5742092457421, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679950, Length=411, Percent_Identity=24.5742092457421, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679946, Length=411, Percent_Identity=24.5742092457421, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788044, Length=383, Percent_Identity=32.8981723237598, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=31.331592689295, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI145693181, Length=363, Percent_Identity=34.7107438016529, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787560, Length=382, Percent_Identity=31.6753926701571, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=28.6069651741293, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786991, Length=337, Percent_Identity=31.1572700296736, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786349, Length=341, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=381, Percent_Identity=29.6587926509186, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32564660, Length=399, Percent_Identity=26.5664160401003, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25144274, Length=250, Percent_Identity=32.4, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=26.2790697674419, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324432, Length=379, Percent_Identity=34.3007915567282, Blast_Score=202, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6323470, Length=392, Percent_Identity=28.8265306122449, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324386, Length=329, Percent_Identity=23.1003039513678, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28574759, Length=391, Percent_Identity=27.8772378516624, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI161085790, Length=393, Percent_Identity=27.2264631043257, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=28.042328042328, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281366494, Length=422, Percent_Identity=26.5402843601896, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667139, Length=422, Percent_Identity=26.5402843601896, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667143, Length=422, Percent_Identity=26.5402843601896, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356575, Length=350, Percent_Identity=24, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 40095; Mature: 40095

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCKVYTPYEFKVEKARGIEIFTDKGVFLDTYSGIGVLALGHSNPEVLTAMKKKLERYTH
CEEEEECCCEEEEECCCCEEEEECCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHH
LSNYFLDEDAEEVAARLVGLSGQVGEVFFTNSGTEATEAALKAIKKLRKGKIVSFVGNFH
HHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCC
GRTIGALSLTYGKAIREPFEPLLTERVFLKPDPEKFTSFARENQIAGVFIECIQGNSGVL
CCEEEEEEHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCHHEEEEEEECCCCCCC
PLSEELLETISQYQREQGFILVADEIQSGLGRTGKAFAYQHFGLKPDIITVGKALGGGLP
CCHHHHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCHHEEHHCCCCCCCEEHHHHHCCCCC
LGAALFSGFSPFKFGEHGSTFAPNPVALAAGKIVLSKLDENFLMQVQEKGKYFREKLAEL
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
PWVQSVNGYGLMIGVTTENASKVKAEAYNRGVLLNIAGGRIRFLPALNITIDEIDEIISR
CCEECCCCCEEEEEEECCCCHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHH
LSFEGF
HCCCCC
>Mature Secondary Structure
MLCKVYTPYEFKVEKARGIEIFTDKGVFLDTYSGIGVLALGHSNPEVLTAMKKKLERYTH
CEEEEECCCEEEEECCCCEEEEECCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHH
LSNYFLDEDAEEVAARLVGLSGQVGEVFFTNSGTEATEAALKAIKKLRKGKIVSFVGNFH
HHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCC
GRTIGALSLTYGKAIREPFEPLLTERVFLKPDPEKFTSFARENQIAGVFIECIQGNSGVL
CCEEEEEEHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCHHEEEEEEECCCCCCC
PLSEELLETISQYQREQGFILVADEIQSGLGRTGKAFAYQHFGLKPDIITVGKALGGGLP
CCHHHHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCHHEEHHCCCCCCCEEHHHHHCCCCC
LGAALFSGFSPFKFGEHGSTFAPNPVALAAGKIVLSKLDENFLMQVQEKGKYFREKLAEL
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
PWVQSVNGYGLMIGVTTENASKVKAEAYNRGVLLNIAGGRIRFLPALNITIDEIDEIISR
CCEECCCCCEEEEEEECCCCHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHH
LSFEGF
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]