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The map label for this gene is dnaA [C]

Identifier: 239616476

GI number: 239616476

Start: 79272

End: 79994

Strand: Reverse

Name: dnaA [C]

Synonym: Kole_0065

Alternate gene names: 239616476

Gene position: 79994-79272 (Counterclockwise)

Preceding gene: 239616477

Following gene: 239616475

Centisome position: 3.47

GC content: 40.66

Gene sequence:

>723_bases
ATGAAAGAACTCATCGCTCAATACTGCAAAGAACTGAGATTGGGAAAAAGTATAGTGGAAAACTACCAAAAGATACAGAC
AGAAACCAACGAGGAATTCCTGGTGAAACTACTGAAGCTGGAGATTGAAAACAGACGGGTATCACGTAAAAATCGTTATC
TAAAACAGGCGAATTTCGAGGTAATGAAAACCTTCGAAGACTACAGTTTTGAAAACGTACAGATACCCAAGAGTATAACA
TTGGAAGAATTACAAGAAGGGAGGTTTCTGGGAAAGAAAGAGAACCTAATACTGTATGGCCCTGTAGGAACAGGAAAAAC
ACACATGGCAACAGCCATAGGTATCGCAGCTTGTAACCGGGAAAAGAAAGTCAGATTTTACAGAACGGCCACACTGGTAA
ATGAACTTGTGGAAGCAAAAAGCAACGGAACATTGAAGAGGTTCTTGAAGACACTCAGAAAGACAGATTTGCTCATATGC
GACGAATGGGGTTACATACCTTTAGACCGAGAAGGAGCGCAACTCTTGTTTCAAGTGATTGCGGAAAGATATGAGAGGAA
CAGCGTAATAATCACAACGAACCTTGAGTTCAGCAAATGGAATGGGATATTCTACGATGAGAAACTCACCAGTGCCATAA
TAGACAGATTGATTCACCATTGCCATTTGTTGGTGTTTACAGGCAAGAGTTACCGATTGGAACATTCGAGTATTAAGGCT
TAA

Upstream 100 bases:

>100_bases
AGAAGTGTGGTTGAAGATAGGGGCAAGGGAACGAAGTACCGAGATTACGAGCGTACGCAACCGATTTTAAGGAATACGAT
GCCCTGGTGGGTGAAAGGAA

Downstream 100 bases:

>100_bases
TTTTTTTACCCCGGGTGCTGGTTTTTTATTTTTCCAAACGCTGGATTTTTATATTGCCAAAAACAGACCTTCTTTTCTCT
TTTATCTTCTAAGTGCATAG

Product: IstB domain protein ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKELIAQYCKELRLGKSIVENYQKIQTETNEEFLVKLLKLEIENRRVSRKNRYLKQANFEVMKTFEDYSFENVQIPKSIT
LEELQEGRFLGKKENLILYGPVGTGKTHMATAIGIAACNREKKVRFYRTATLVNELVEAKSNGTLKRFLKTLRKTDLLIC
DEWGYIPLDREGAQLLFQVIAERYERNSVIITTNLEFSKWNGIFYDEKLTSAIIDRLIHHCHLLVFTGKSYRLEHSSIKA

Sequences:

>Translated_240_residues
MKELIAQYCKELRLGKSIVENYQKIQTETNEEFLVKLLKLEIENRRVSRKNRYLKQANFEVMKTFEDYSFENVQIPKSIT
LEELQEGRFLGKKENLILYGPVGTGKTHMATAIGIAACNREKKVRFYRTATLVNELVEAKSNGTLKRFLKTLRKTDLLIC
DEWGYIPLDREGAQLLFQVIAERYERNSVIITTNLEFSKWNGIFYDEKLTSAIIDRLIHHCHLLVFTGKSYRLEHSSIKA
>Mature_240_residues
MKELIAQYCKELRLGKSIVENYQKIQTETNEEFLVKLLKLEIENRRVSRKNRYLKQANFEVMKTFEDYSFENVQIPKSIT
LEELQEGRFLGKKENLILYGPVGTGKTHMATAIGIAACNREKKVRFYRTATLVNELVEAKSNGTLKRFLKTLRKTDLLIC
DEWGYIPLDREGAQLLFQVIAERYERNSVIITTNLEFSKWNGIFYDEKLTSAIIDRLIHHCHLLVFTGKSYRLEHSSIKA

Specific function: Plays An Important Role In The Initiation And Regulation Of Chromosomal Replication. Binds To The Origin Of Replication; It Binds Specifically Double-Stranded DNA At A 9 Bp Consensus (Dnaa Box): 5'-TTATC[Ca]A[Ca]A-3'. Dnaa Binds To ATP And To Acidic Phosp

COG id: COG1484

COG function: function code L; DNA replication protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IS21/IS1162 putative ATP-binding protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001270
- InterPro:   IPR002611 [H]

Pfam domain/function: PF01695 IstB [H]

EC number: NA

Molecular weight: Translated: 28033; Mature: 28033

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELIAQYCKELRLGKSIVENYQKIQTETNEEFLVKLLKLEIENRRVSRKNRYLKQANFE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VMKTFEDYSFENVQIPKSITLEELQEGRFLGKKENLILYGPVGTGKTHMATAIGIAACNR
HHHHHHHCCCCCEECCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCC
EKKVRFYRTATLVNELVEAKSNGTLKRFLKTLRKTDLLICDEWGYIPLDREGAQLLFQVI
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHH
AERYERNSVIITTNLEFSKWNGIFYDEKLTSAIIDRLIHHCHLLVFTGKSYRLEHSSIKA
HHHHCCCCEEEEECCCHHHCCCEEEHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCCC
>Mature Secondary Structure
MKELIAQYCKELRLGKSIVENYQKIQTETNEEFLVKLLKLEIENRRVSRKNRYLKQANFE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VMKTFEDYSFENVQIPKSITLEELQEGRFLGKKENLILYGPVGTGKTHMATAIGIAACNR
HHHHHHHCCCCCEECCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCC
EKKVRFYRTATLVNELVEAKSNGTLKRFLKTLRKTDLLICDEWGYIPLDREGAQLLFQVI
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHH
AERYERNSVIITTNLEFSKWNGIFYDEKLTSAIIDRLIHHCHLLVFTGKSYRLEHSSIKA
HHHHCCCCEEEEECCCHHHCCCEEEHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2174857 [H]