| Definition | Kosmotoga olearia TBF 19.5.1, complete genome. |
|---|---|
| Accession | NC_012785 |
| Length | 2,302,126 |
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The map label for this gene is uvrA [H]
Identifier: 239616457
GI number: 239616457
Start: 52745
End: 55573
Strand: Reverse
Name: uvrA [H]
Synonym: Kole_0046
Alternate gene names: 239616457
Gene position: 55573-52745 (Counterclockwise)
Preceding gene: 239616458
Following gene: 239616452
Centisome position: 2.41
GC content: 48.18
Gene sequence:
>2829_bases ATGAATGACTTTATCTATGTGAAAGGTGCAAGGGTACATAACCTTAAAAACATAGACGTTAAAATTCCGAAGAATTCACT GACGGTTATCACTGGGCTTTCGGGTTCCGGGAAGTCTTCCCTTGCTCTGGACACAATTTACGCTGAGGGGCAGAGGCGCT ACCTGGAATCCCTCTCAAACTACGCCAGGCAGTTCCTTGGAGAGCTGAAGAAGCCGGATGTTGAGAGCATCGAAGGCCTT TCGCCGGCGATTGCTATAGAACAGAAAACGGTGAGCCACAACCCGCGTTCGACGGTGGGAACGGTTACGGAGATTCACGA CTATCTGCGTATTCTCTACGCGAGAATCGGCCAACCCCACTGTCCAAAATGCGGAAGGCCCGTTGAAAAGCAATCGCTGG ATGAAATTCTTGAACATGTTTCCAGGGATTTTCCTGAAGGCACCAGAATAGCTGTTTATGCTCCCATTGCTAAGGAAAAG AAAGGGGAGTTCAAAAAGGAACTGGATCTCCTCAAGAAAAAAGGGTATGTACGAATAGAGATAGACGGGATCATATACGA CCTCGAAGATGAGCTCTCTCTGGATAAAAACAAGCGCCACACCATCAATCTGGTGGTGGATAGGTTGAAGGTCAGGGAAG AGAATAAATCGAGGCTCGCTGACAGTATAGAGATGGCGCTCCATGAGGGTAACGGATTCGTCGAGATAGTGAATCTCGAC AATCTTCAGAAGAAGATATTCAGCGAACATTTTGCCTGTCCCGTATGCGGGATAAGTCTCCCGGAAATCAACCCAAAGAT TTTCTCTTTCAACAATCCCTATGGAGCCTGTCCGGAGTGTCACGGTCTCGGGTTCACAAGGGAGTTTTCCGAAGAGCTTG TAATCGACAGGGAGCTTAGTATAAGAGATGGAGCTATCCGTGCCTTTTCTAATTCCTTCGATAGTTTTACCATGAGGATG ATCATGCGGGTTCTGGAATGGCTCGGGGAGAGCCCCGATAAACCCTTCAAGGATCTTTCCGAAGAAGCTCAAAGGGTCAT TCTCTACGGCACGAGAGAAGAGCTCAGCTTCTCATTCCAGTCTGAAAGGCTCTCATACAAGATAAGAAAACCCTTTGAAG GGGTTATGAACAACCTCAAGAGACGGTACAGGGAAACCCAATCCGGGGATATTCGCGAATGGATGGAAAGCAAATTTATG GTGACTCAGGAATGCCCCCGCTGTCACGGTCAGCGTTTGAGGGCAGAAGCGCTTGCTGTAAAAATAGACGGCAAAAATAT CTCCGAGCTATCTGACCTAACTATCCGCGAGATATACGATTTTCTTGGGGAATTAAAGTTAACGGAGCATCAGGAAAAGA TCGTCGGTGAATTGCTCAGGGAGATCAAAAGGCGCTTGAAGTTTCTTATAGATGTGGGGCTGGATTATATAACGCTGTCC CGTTCGGCTACTACCCTTTCCGGTGGGGAAGCGCAGCGAATCCGGCTTGCCACGCAGATAGGTTCAGGATTGACCGGCGT AACCTATGTGCTGGATGAGCCAACCATAGGCTTGCATTCCAGGGATAACGCGAGATTGATTAAGACCCTGAAAAATCTCC GGGATCTCGGGAACACGGTGATAGTTGTTGAACACGATGAAGAGGTCATTAGAAACTCAGACTACATAGTCGATGTAGGC CCTAAAGCCGGGATTCATGGAGGAGAGGTTGTCTTTCAGGGCCCAACCAAAAAATTGCTGGACAACCCGCCAGAAAATTC ATTGACGGGAAAATATTTAAGGGGCGAGCTTAAAATCCCCAGATTTGACAGTAGAAACGTTAAGGCCAAAAAGAAATTGA TCTTGAAAGGCGCAAGACAAAACAATTTGAAGTCCATAGACGTTGAGTTCCCGCTTGGAAAGTTCATCTGCGTGACCGGT GTTTCCGGAAGCGGAAAAAGCTCCCTCGTAATGGATACCCTTTATCCCGCACTGAGCAATCGGTTGAACAGGTCGCGGCT TCCCGAAGGTAAATATGACGATATTATAGGTGTAGAGGAACTCGATAATGTCATCGTGATAGATCAGAGCCCCATCGGGA GAACCCCGAGATCCAATCCGGCAACCTACACCGGTCTTTTTGACCATGTCAGGGATCTCTTTGCGAAAACACCGGAGGCT CGCGCAAGGGGTTACAAGAAAGGCCGATTTTCATTCAATGTCAAAGGCGGCCGGTGTGAAGCCTGTCAGGGGCACGGATT GCTGAAGATTGAGATGCAGTTCCTCCCGGATGTCTATGTGGAGTGTGATGTCTGTAAAGGTAAAAGGTACAACAAGGAGA CCCTTGAAATCGAGTATAAGGGAAAGAACATCGCCGATGTGTTGAACATGACGGTTGAAGAGGCGCTTGAATTCTTTGAA AGGATACCGCCTTTGCAAAGAATTCTTTCGCTTCTGAACGATGTCGGGCTTGGCTATATAGCGCTTGGACAGCCGGCTAC AACCCTTTCCGGTGGGGAAGCGCAGAGGATAAAGCTCGCCGCGGAGTTGAAGAAACGCTCAACTGGCAGGACTTTCTATA TCCTCGACGAACCGACAACCGGGCTGCACTTCGATGACGTTTCAAAACTTGTTAAGGTTCTGGGAAGGCTTGTGGAAAAA GGAAACACCGTTGTTGTCGTTGAGCACAACATGGACGTGGTAAAAAATGCCGATTACATAATCGATCTTGGCCCCGAAGG CGGAGATGGTGGCGGGCAGATCGTTGTTGCGGGAACCCCTGAAGAGGTAGCGGCCTGTAAAAAGAGCTACACAGGCTATT ATCTACGGAAACATTTGAACCTTAAATAG
Upstream 100 bases:
>100_bases GGTACGGAGCCTTATATAAGGGTTATGGTGGAAGGCATGGACGAAGGAAAGGTTTCTGAAATAGTAGAAAGGATCGTGGA GGTGCTGGAGGACTGTAGCA
Downstream 100 bases:
>100_bases AGGCTATTAGAAGGAAAAATGGAGAACATAAAGAGGGGGGAGCTTTCGCTCCCCCTTTTATCATTGGTGGAGTCGATGGG ATTCGAACCCACGACTTTCG
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 942; Mature: 942
Protein sequence:
>942_residues MNDFIYVKGARVHNLKNIDVKIPKNSLTVITGLSGSGKSSLALDTIYAEGQRRYLESLSNYARQFLGELKKPDVESIEGL SPAIAIEQKTVSHNPRSTVGTVTEIHDYLRILYARIGQPHCPKCGRPVEKQSLDEILEHVSRDFPEGTRIAVYAPIAKEK KGEFKKELDLLKKKGYVRIEIDGIIYDLEDELSLDKNKRHTINLVVDRLKVREENKSRLADSIEMALHEGNGFVEIVNLD NLQKKIFSEHFACPVCGISLPEINPKIFSFNNPYGACPECHGLGFTREFSEELVIDRELSIRDGAIRAFSNSFDSFTMRM IMRVLEWLGESPDKPFKDLSEEAQRVILYGTREELSFSFQSERLSYKIRKPFEGVMNNLKRRYRETQSGDIREWMESKFM VTQECPRCHGQRLRAEALAVKIDGKNISELSDLTIREIYDFLGELKLTEHQEKIVGELLREIKRRLKFLIDVGLDYITLS RSATTLSGGEAQRIRLATQIGSGLTGVTYVLDEPTIGLHSRDNARLIKTLKNLRDLGNTVIVVEHDEEVIRNSDYIVDVG PKAGIHGGEVVFQGPTKKLLDNPPENSLTGKYLRGELKIPRFDSRNVKAKKKLILKGARQNNLKSIDVEFPLGKFICVTG VSGSGKSSLVMDTLYPALSNRLNRSRLPEGKYDDIIGVEELDNVIVIDQSPIGRTPRSNPATYTGLFDHVRDLFAKTPEA RARGYKKGRFSFNVKGGRCEACQGHGLLKIEMQFLPDVYVECDVCKGKRYNKETLEIEYKGKNIADVLNMTVEEALEFFE RIPPLQRILSLLNDVGLGYIALGQPATTLSGGEAQRIKLAAELKKRSTGRTFYILDEPTTGLHFDDVSKLVKVLGRLVEK GNTVVVVEHNMDVVKNADYIIDLGPEGGDGGGQIVVAGTPEEVAACKKSYTGYYLRKHLNLK
Sequences:
>Translated_942_residues MNDFIYVKGARVHNLKNIDVKIPKNSLTVITGLSGSGKSSLALDTIYAEGQRRYLESLSNYARQFLGELKKPDVESIEGL SPAIAIEQKTVSHNPRSTVGTVTEIHDYLRILYARIGQPHCPKCGRPVEKQSLDEILEHVSRDFPEGTRIAVYAPIAKEK KGEFKKELDLLKKKGYVRIEIDGIIYDLEDELSLDKNKRHTINLVVDRLKVREENKSRLADSIEMALHEGNGFVEIVNLD NLQKKIFSEHFACPVCGISLPEINPKIFSFNNPYGACPECHGLGFTREFSEELVIDRELSIRDGAIRAFSNSFDSFTMRM IMRVLEWLGESPDKPFKDLSEEAQRVILYGTREELSFSFQSERLSYKIRKPFEGVMNNLKRRYRETQSGDIREWMESKFM VTQECPRCHGQRLRAEALAVKIDGKNISELSDLTIREIYDFLGELKLTEHQEKIVGELLREIKRRLKFLIDVGLDYITLS RSATTLSGGEAQRIRLATQIGSGLTGVTYVLDEPTIGLHSRDNARLIKTLKNLRDLGNTVIVVEHDEEVIRNSDYIVDVG PKAGIHGGEVVFQGPTKKLLDNPPENSLTGKYLRGELKIPRFDSRNVKAKKKLILKGARQNNLKSIDVEFPLGKFICVTG VSGSGKSSLVMDTLYPALSNRLNRSRLPEGKYDDIIGVEELDNVIVIDQSPIGRTPRSNPATYTGLFDHVRDLFAKTPEA RARGYKKGRFSFNVKGGRCEACQGHGLLKIEMQFLPDVYVECDVCKGKRYNKETLEIEYKGKNIADVLNMTVEEALEFFE RIPPLQRILSLLNDVGLGYIALGQPATTLSGGEAQRIKLAAELKKRSTGRTFYILDEPTTGLHFDDVSKLVKVLGRLVEK GNTVVVVEHNMDVVKNADYIIDLGPEGGDGGGQIVVAGTPEEVAACKKSYTGYYLRKHLNLK >Mature_942_residues MNDFIYVKGARVHNLKNIDVKIPKNSLTVITGLSGSGKSSLALDTIYAEGQRRYLESLSNYARQFLGELKKPDVESIEGL SPAIAIEQKTVSHNPRSTVGTVTEIHDYLRILYARIGQPHCPKCGRPVEKQSLDEILEHVSRDFPEGTRIAVYAPIAKEK KGEFKKELDLLKKKGYVRIEIDGIIYDLEDELSLDKNKRHTINLVVDRLKVREENKSRLADSIEMALHEGNGFVEIVNLD NLQKKIFSEHFACPVCGISLPEINPKIFSFNNPYGACPECHGLGFTREFSEELVIDRELSIRDGAIRAFSNSFDSFTMRM IMRVLEWLGESPDKPFKDLSEEAQRVILYGTREELSFSFQSERLSYKIRKPFEGVMNNLKRRYRETQSGDIREWMESKFM VTQECPRCHGQRLRAEALAVKIDGKNISELSDLTIREIYDFLGELKLTEHQEKIVGELLREIKRRLKFLIDVGLDYITLS RSATTLSGGEAQRIRLATQIGSGLTGVTYVLDEPTIGLHSRDNARLIKTLKNLRDLGNTVIVVEHDEEVIRNSDYIVDVG PKAGIHGGEVVFQGPTKKLLDNPPENSLTGKYLRGELKIPRFDSRNVKAKKKLILKGARQNNLKSIDVEFPLGKFICVTG VSGSGKSSLVMDTLYPALSNRLNRSRLPEGKYDDIIGVEELDNVIVIDQSPIGRTPRSNPATYTGLFDHVRDLFAKTPEA RARGYKKGRFSFNVKGGRCEACQGHGLLKIEMQFLPDVYVECDVCKGKRYNKETLEIEYKGKNIADVLNMTVEEALEFFE RIPPLQRILSLLNDVGLGYIALGQPATTLSGGEAQRIKLAAELKKRSTGRTFYILDEPTTGLHFDDVSKLVKVLGRLVEK GNTVVVVEHNMDVVKNADYIIDLGPEGGDGGGQIVVAGTPEEVAACKKSYTGYYLRKHLNLK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=945, Percent_Identity=56.0846560846561, Blast_Score=1044, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 105904; Mature: 105904
Theoretical pI: Translated: 8.28; Mature: 8.28
Prosite motif: PS00063 ALDOKETO_REDUCTASE_3 ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNDFIYVKGARVHNLKNIDVKIPKNSLTVITGLSGSGKSSLALDTIYAEGQRRYLESLSN CCCEEEEECCEEECCCCCEEEECCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHH YARQFLGELKKPDVESIEGLSPAIAIEQKTVSHNPRSTVGTVTEIHDYLRILYARIGQPH HHHHHHHHCCCCCHHHHCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC CPKCGRPVEKQSLDEILEHVSRDFPEGTRIAVYAPIAKEKKGEFKKELDLLKKKGYVRIE CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCHHHHHHHHHHHCCEEEEE IDGIIYDLEDELSLDKNKRHTINLVVDRLKVREENKSRLADSIEMALHEGNGFVEIVNLD EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC NLQKKIFSEHFACPVCGISLPEINPKIFSFNNPYGACPECHGLGFTREFSEELVIDRELS HHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHEECCCCC IRDGAIRAFSNSFDSFTMRMIMRVLEWLGESPDKPFKDLSEEAQRVILYGTREELSFSFQ CCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEEEECHHHHCEEEC SERLSYKIRKPFEGVMNNLKRRYRETQSGDIREWMESKFMVTQECPRCHGQRLRAEALAV HHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCHHHHHHHHEEEEEEE KIDGKNISELSDLTIREIYDFLGELKLTEHQEKIVGELLREIKRRLKFLIDVGLDYITLS EECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC RSATTLSGGEAQRIRLATQIGSGLTGVTYVLDEPTIGLHSRDNARLIKTLKNLRDLGNTV CCCCCCCCCCCHHEEEEHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEE IVVEHDEEVIRNSDYIVDVGPKAGIHGGEVVFQGPTKKLLDNPPENSLTGKYLRGELKIP EEEECCHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCEEECEECCC RFDSRNVKAKKKLILKGARQNNLKSIDVEFPLGKFICVTGVSGSGKSSLVMDTLYPALSN CCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHH RLNRSRLPEGKYDDIIGVEELDNVIVIDQSPIGRTPRSNPATYTGLFDHVRDLFAKTPEA HHHHHCCCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHH RARGYKKGRFSFNVKGGRCEACQGHGLLKIEMQFLPDVYVECDVCKGKRYNKETLEIEYK HHCCCCCCCEEEEECCCEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEC GKNIADVLNMTVEEALEFFERIPPLQRILSLLNDVGLGYIALGQPATTLSGGEAQRIKLA CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHH AELKKRSTGRTFYILDEPTTGLHFDDVSKLVKVLGRLVEKGNTVVVVEHNMDVVKNADYI HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCEE IDLGPEGGDGGGQIVVAGTPEEVAACKKSYTGYYLRKHLNLK EEECCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHCCCCC >Mature Secondary Structure MNDFIYVKGARVHNLKNIDVKIPKNSLTVITGLSGSGKSSLALDTIYAEGQRRYLESLSN CCCEEEEECCEEECCCCCEEEECCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHH YARQFLGELKKPDVESIEGLSPAIAIEQKTVSHNPRSTVGTVTEIHDYLRILYARIGQPH HHHHHHHHCCCCCHHHHCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC CPKCGRPVEKQSLDEILEHVSRDFPEGTRIAVYAPIAKEKKGEFKKELDLLKKKGYVRIE CCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCHHHHHHHHHHHCCEEEEE IDGIIYDLEDELSLDKNKRHTINLVVDRLKVREENKSRLADSIEMALHEGNGFVEIVNLD EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC NLQKKIFSEHFACPVCGISLPEINPKIFSFNNPYGACPECHGLGFTREFSEELVIDRELS HHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHEECCCCC IRDGAIRAFSNSFDSFTMRMIMRVLEWLGESPDKPFKDLSEEAQRVILYGTREELSFSFQ CCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEEEECHHHHCEEEC SERLSYKIRKPFEGVMNNLKRRYRETQSGDIREWMESKFMVTQECPRCHGQRLRAEALAV HHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCHHHHHHHHEEEEEEE KIDGKNISELSDLTIREIYDFLGELKLTEHQEKIVGELLREIKRRLKFLIDVGLDYITLS EECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC RSATTLSGGEAQRIRLATQIGSGLTGVTYVLDEPTIGLHSRDNARLIKTLKNLRDLGNTV CCCCCCCCCCCHHEEEEHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEE IVVEHDEEVIRNSDYIVDVGPKAGIHGGEVVFQGPTKKLLDNPPENSLTGKYLRGELKIP EEEECCHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCEEECEECCC RFDSRNVKAKKKLILKGARQNNLKSIDVEFPLGKFICVTGVSGSGKSSLVMDTLYPALSN CCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHH RLNRSRLPEGKYDDIIGVEELDNVIVIDQSPIGRTPRSNPATYTGLFDHVRDLFAKTPEA HHHHHCCCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHH RARGYKKGRFSFNVKGGRCEACQGHGLLKIEMQFLPDVYVECDVCKGKRYNKETLEIEYK HHCCCCCCCEEEEECCCEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEC GKNIADVLNMTVEEALEFFERIPPLQRILSLLNDVGLGYIALGQPATTLSGGEAQRIKLA CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHH AELKKRSTGRTFYILDEPTTGLHFDDVSKLVKVLGRLVEKGNTVVVVEHNMDVVKNADYI HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCEE IDLGPEGGDGGGQIVVAGTPEEVAACKKSYTGYYLRKHLNLK EEECCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]