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The map label for this gene is yoeA [H]

Identifier: 238926027

GI number: 238926027

Start: 3426363

End: 3427715

Strand: Reverse

Name: yoeA [H]

Synonym: EUBREC_3685

Alternate gene names: 238926027

Gene position: 3427715-3426363 (Counterclockwise)

Preceding gene: 238926029

Following gene: 238926026

Centisome position: 99.36

GC content: 43.61

Gene sequence:

>1353_bases
ATGGTAACAAATGAAAAAAATATGACCACTGGATCACCTGGAAAACTGATCATTACTTTTGCCATACCACTGATGCTTGG
AAATATCTTTCAGCAGTTTTATACGATGGCAGATACCATGATCGTCGGACAGGTGGTAGGGGTTGAAGCACTGGCGGCAG
TAGGCGCCGGAGACTGGCTGGTATGGCTGGTGTTCGGTATCATGACAGGTATCACACAGGGTTTTTCTATTCTGGTAGCT
CAATTTTATGGAGCAAGGGAAAAAGAAAATCTGAAATGCGCGGTGGCGAAAAGCTATATCATGACAGCACTGCTTTCTGT
GATTGTACTTGCGGTAAGTGAAGGGGCAGTTTATCATGTTCTTTTGTTTTTACAGACACCGGATAATGTCATTGACCTGA
CAATGCTATATCTTCGGCTGATCTTTGCCGGAATTCCGATCATAGCGGCTTATAATATATTTGCAGCGATTCTTCGAGCA
CTGGGTAACAGCAGATCTCCACTGATAGCAATGACCGTAGCAGCGTTGATCAATGTGGGACTGGACCTGTTATTTGTGGC
AGTTTTTGGCTGGGGTGTAGCCGGAGCAGCAGTGGCGACAGTCATCGCACAGGGATTTTCAGCCCTGTACTGTCTGATGG
TGTTACGGAAAATTCCGGATATCCGACTGGAAAAACAGGACTTCTACAGACAGCCGGCAATGAGTCTGCGGCTTTTGAAA
GTGGCGACTCCTCTTGCAATCCAGAATTTGATCATCTCTGTAGGGGGGCTTACAGTACAGTATGTAGTCAATGGATTTGG
ATTCCTGTTTGTGGCTGGATTTACAGCATCAAACAAATTATATGGAGTTTTAGAGATGGCTGCCGTTTCATACGGATATG
CAATTACAACCTATGTAGGCCAGAATCTTGGTGCAAAGAAATATCAGAGAATCCGGAAAGGTGTGCATAGCGGAACTTAT
ATGGCATTGCTTACTGCTGTTGTGATCTCAGGTGTGATGGTGTTATTCGGACGCAATATATTGTCACTGTTTGTATCCGG
CGAACAGGAACAGATCCGACAGGTGTTAGACATTGCATATAAATATTTGTTTATTATGGCAATTTTTCTATGGGTACTGT
ATCTGCTGTATGTATATCGTTCGGCGATTCAGGGTCTGGGTAATACCCTGATTCCCCTCGCCAGTGGCATTGCAGAATTT
GCGATGCGTGTCAGTGTTGCATTATTGTTACCAAAACTGATCGGTGAAGACGGAATTTTTTATGCGGAAATTTGTGCCTG
GACCAGCGCAGCTGTTTTATTGTTTATAAGTTATATGATTATTATACGAAAATACAAAGAGTATAACTGCTGA

Upstream 100 bases:

>100_bases
CTGGTGGGACGATATACCAAAGAGTTCTGTGATGGATTGCGTTTTGACAGAGTCCAATGTGAAATAATCGGACAAGGATG
AAAAGAAAAAGGAGATTCTT

Downstream 100 bases:

>100_bases
CTGTTAAGTAAAAATAGTTCGACTCCATGGACAAAAAGGTGTATAATAAAATAAAACTTCAGTATATTAAGGAAAAAGAT
ATTATAATCTTCCAGCAACT

Product: hypothetical protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MVTNEKNMTTGSPGKLIITFAIPLMLGNIFQQFYTMADTMIVGQVVGVEALAAVGAGDWLVWLVFGIMTGITQGFSILVA
QFYGAREKENLKCAVAKSYIMTALLSVIVLAVSEGAVYHVLLFLQTPDNVIDLTMLYLRLIFAGIPIIAAYNIFAAILRA
LGNSRSPLIAMTVAALINVGLDLLFVAVFGWGVAGAAVATVIAQGFSALYCLMVLRKIPDIRLEKQDFYRQPAMSLRLLK
VATPLAIQNLIISVGGLTVQYVVNGFGFLFVAGFTASNKLYGVLEMAAVSYGYAITTYVGQNLGAKKYQRIRKGVHSGTY
MALLTAVVISGVMVLFGRNILSLFVSGEQEQIRQVLDIAYKYLFIMAIFLWVLYLLYVYRSAIQGLGNTLIPLASGIAEF
AMRVSVALLLPKLIGEDGIFYAEICAWTSAAVLLFISYMIIIRKYKEYNC

Sequences:

>Translated_450_residues
MVTNEKNMTTGSPGKLIITFAIPLMLGNIFQQFYTMADTMIVGQVVGVEALAAVGAGDWLVWLVFGIMTGITQGFSILVA
QFYGAREKENLKCAVAKSYIMTALLSVIVLAVSEGAVYHVLLFLQTPDNVIDLTMLYLRLIFAGIPIIAAYNIFAAILRA
LGNSRSPLIAMTVAALINVGLDLLFVAVFGWGVAGAAVATVIAQGFSALYCLMVLRKIPDIRLEKQDFYRQPAMSLRLLK
VATPLAIQNLIISVGGLTVQYVVNGFGFLFVAGFTASNKLYGVLEMAAVSYGYAITTYVGQNLGAKKYQRIRKGVHSGTY
MALLTAVVISGVMVLFGRNILSLFVSGEQEQIRQVLDIAYKYLFIMAIFLWVLYLLYVYRSAIQGLGNTLIPLASGIAEF
AMRVSVALLLPKLIGEDGIFYAEICAWTSAAVLLFISYMIIIRKYKEYNC
>Mature_450_residues
MVTNEKNMTTGSPGKLIITFAIPLMLGNIFQQFYTMADTMIVGQVVGVEALAAVGAGDWLVWLVFGIMTGITQGFSILVA
QFYGAREKENLKCAVAKSYIMTALLSVIVLAVSEGAVYHVLLFLQTPDNVIDLTMLYLRLIFAGIPIIAAYNIFAAILRA
LGNSRSPLIAMTVAALINVGLDLLFVAVFGWGVAGAAVATVIAQGFSALYCLMVLRKIPDIRLEKQDFYRQPAMSLRLLK
VATPLAIQNLIISVGGLTVQYVVNGFGFLFVAGFTASNKLYGVLEMAAVSYGYAITTYVGQNLGAKKYQRIRKGVHSGTY
MALLTAVVISGVMVLFGRNILSLFVSGEQEQIRQVLDIAYKYLFIMAIFLWVLYLLYVYRSAIQGLGNTLIPLASGIAEF
AMRVSVALLLPKLIGEDGIFYAEICAWTSAAVLLFISYMIIIRKYKEYNC

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI48994890, Length=334, Percent_Identity=24.8502994011976, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI226510954, Length=434, Percent_Identity=20.5069124423963, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49133; Mature: 49133

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]