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The map label for this gene is lacA [C]

Identifier: 238925963

GI number: 238925963

Start: 3382765

End: 3383055

Strand: Direct

Name: lacA [C]

Synonym: EUBREC_3621

Alternate gene names: 238925963

Gene position: 3382765-3383055 (Clockwise)

Preceding gene: 238925962

Following gene: 238925964

Centisome position: 98.06

GC content: 43.3

Gene sequence:

>291_bases
GTGTATTACGAATCCAGTGATTTTTTGGAAACTGCAGACAGCGATACGTTAAAGCAGATTGCCCGCACAAGGGAATTAAC
AAGGGAATATTATTTTTCTGATTATGGAGATACAGAAAAACGCACTTCTATTCTTCGGGAGCTGTTGGGTGGAATAGGGG
AAAACAGCGTGATAGGGGCTGGAAGTGTAGTTACCCGCCCTATCCCGCCTAATTGTGTTGCAGTAGGAAATCCATGCAGG
GTGATACATTATTTTGATACAGACAGGGAAAGGTGGCAGCATGAAGTATAA

Upstream 100 bases:

>100_bases
TTTTAGAGATTAAAGAACAGTTTGAAAATCAGATCGGCTGTTCTATCTATTCTCTGCTTCCGGGTATTGTGGAAAACAGT
TTTCGTTAAGGGGGGATATT

Downstream 100 bases:

>100_bases
GCATATCGTTTTTGACATTGACGGCACTCTGATTGATACGGAATATGCTGTATTACATTCTTTACAGGAAACTATAAAGG
AATTGTCCGGGAGAAAGATA

Product: putative acetyltransferase in HXT11-HXT8 intergenic region

Products: CoA; aacetyl-beta-D-galactoside [C]

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MYYESSDFLETADSDTLKQIARTRELTREYYFSDYGDTEKRTSILRELLGGIGENSVIGAGSVVTRPIPPNCVAVGNPCR
VIHYFDTDRERWQHEV

Sequences:

>Translated_96_residues
MYYESSDFLETADSDTLKQIARTRELTREYYFSDYGDTEKRTSILRELLGGIGENSVIGAGSVVTRPIPPNCVAVGNPCR
VIHYFDTDRERWQHEV
>Mature_96_residues
MYYESSDFLETADSDTLKQIARTRELTREYYFSDYGDTEKRTSILRELLGGIGENSVIGAGSVVTRPIPPNCVAVGNPCR
VIHYFDTDRERWQHEV

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.18 [C]

Molecular weight: Translated: 11007; Mature: 11007

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYESSDFLETADSDTLKQIARTRELTREYYFSDYGDTEKRTSILRELLGGIGENSVIGA
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECC
GSVVTRPIPPNCVAVGNPCRVIHYFDTDRERWQHEV
CCEEECCCCCCEEEECCCEEEEEECCCCHHHHCCCC
>Mature Secondary Structure
MYYESSDFLETADSDTLKQIARTRELTREYYFSDYGDTEKRTSILRELLGGIGENSVIGA
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECC
GSVVTRPIPPNCVAVGNPCRVIHYFDTDRERWQHEV
CCEEECCCCCCEEEECCCEEEEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: MgSO4; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.18 {acetyl-CoA}} 0.049 {acetyl-CoA}} 0.045 {acetyl-CoA}} 0.04 {acetyl-CoA}} 1500 {isopropyl} 1200 {isopropyl} 770 {isopropyl} 360 {isopropyl} [C]

Substrates: Acetyl-CoA; a beta-D-galactoside [C]

Specific reaction: Acetyl-CoA + a beta-D-galactoside = CoA + aacetyl-beta-D-galactoside [C]

General reaction: Acyl group transfer [C]

Inhibitor: 1, 10-Phenanthroline; Acetyl-CoA; Co2+; CoA; Cu2+; MgSO4; Mn2+; p-Chloromercuribenzoate; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA