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The map label for this gene is cisA [H]

Identifier: 238925943

GI number: 238925943

Start: 3368419

End: 3370281

Strand: Reverse

Name: cisA [H]

Synonym: EUBREC_3601

Alternate gene names: 238925943

Gene position: 3370281-3368419 (Counterclockwise)

Preceding gene: 238925944

Following gene: 238925942

Centisome position: 97.7

GC content: 43.69

Gene sequence:

>1863_bases
ATGAGTAGTGAGAAAATAATTGTATTATATGAACGATTAAGCCGAGAGGATGAGAACCTTGGGGAGTCGTACAGTATATC
AAATCAAAAGAAGCTGCTGGAAGATTATTGCAGAGAAAAAGGGTGGACCAGGTTCAGGCACTTCACTGATGATGGTATAT
CCGGCACAACCTTTGACAGACCATCCTTTAAGGCTATGATACAGCTTGTGGAAGATGGAGAAGTGGAAACCATTATTCTA
AAGGATATGAGCCGGTTAGGGCGGGATTATCTTGTGGTAGGTCAGCTCCGGGAGTTCTTTCGCAAAAAGGGAGTTCGTCT
GATTGCAATTAACGATAATCATGACAGTTACAATGGAGATGACGATTTCCTTGTATTCAGGGATGTTATGAATGAAATGT
ATGCCAAGGATATCAGCAAAAAGATAAAATCCACATTCAAATCCAAGGGAAAATCCGGAAAGCATGTGGCAAGTGTTACA
CCATACGGATACCTGAAAGATGAAAATGACGGAAACCATTGGATTGTGGATGAAGAAGCTGCCGAAATTGTGAGGCTGAT
ATTCAAATGGACTATTGATGGGCTGGGTCCTTATCAGATAGCAAAACTTCTGCAGGAGAAAAAAGTGGAAATACCGGCAG
TGCATATGGCACGCTTCGGGCAGGGGAATAACAGAAACAAGAAAGTGAAAGACCCTTATGGATGGGGTTCTTCTACAGTA
GTCGGGATATTGAAGAAAAGGGAATACTTAGGTCACACGGTCAATTTTAAAACACAGAAGCATTTTAAGGATAAAAAGAG
CCATTATGTATCAGAGGACAACTGGGTAATATTTGAGAATACGCAGGAGCCGATTATTGACCAGCAGACCTTTGATACAG
TGCAGAAATTACGGGAAAATGTAAGGAGATACCCGGACGGATGGGGAGAGCATCATGTTCTTACCGGTCTTATGTATTGT
GCTGACTGTGGTGCAAAAATGTATGTGCACCGGACAAGCAATGGAAAGAGGATTGCCCAGTATACCTGTTCTGCTTATAC
CAAGGTACCTTGCGGAACATTGTGCAAGACACAGCACAGGATTAACGAGTCAGTGGTGCTGGAACTGATAGGAGACACAC
TCAGGGCAATCTTTGAATATGCAAAGTATGACCGGAGCGAGTTCATAGACACCATAACAATGGCACAGTCAACACAGGAG
GATGCAGAGGTAAAAAAGGTCAGGGCAAGAATCGCAGTGGCTGGAAATCGCTGTGAGGAGCTGGAGAAGCTAATCTGCCG
TATTTATGAGGACAATATTCTCGGCAAACTACCGGACAGCAGATATGAGGTTCTTGATAAGCAGTATGCCAGGGAAAAAG
CGGAGCTGGATGCAGAGATTAAGGAGCTGGAAGCGAAGCTCACAGAATATGAGAAAAGCAGAAATTCTGCCGGCAAGTTT
ATTGCACTGATTGATAAATATGAGAAGTTCGAGGAACTGACACCGGCAATGGTAAATGAATTTGTTGATAAGGTGCTGGT
GCATGAAAGAGACAGAAAGGGGAGCATCCAAACCACGCAGGAGATTGAAATCTATTTCAATTTTGTTGGTCGGTATGTTC
CACCGGCAATGATGACAGAACCTACTGCTGAAGAGCAGGCTGAGATTGACCGGATTAACAGAATCAAGGACAGGAGACAT
CAGCAGTATTTACGAAGAAAAGAAAGTGGATGGCAGAGGAAATATGAAGAGCGTGTAAAAAATGAAAAGCGTGCAAAAAT
GCAGGCAATGAAAGAAGAAATCCGCAGGCAGGACAGGGAGAACGGAGTCTATGCAACGGCAGGCAGTCTTGCATTGGAAC
CGACGATTGGAATGCCTGAATAG

Upstream 100 bases:

>100_bases
GGTGTAATAAGATGAAAGAGACTTTTTAGTACCTTAACAGATTAAAGATTCTCTTTGAGCTTATTACTTTTGGCTCAAAT
ACAGAGGAAAGGAGCAGAAC

Downstream 100 bases:

>100_bases
GATTTCGCAGAAAGCACTTGAGAGAAGTCTTGGGTGCTTTTTTCATGCTCAAATTTCCGCAGGAAATGCAGGGCAACCGG
AGAAGTTGAACTGTGTTATC

Product: DNA recombinase, putative

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MSSEKIIVLYERLSREDENLGESYSISNQKKLLEDYCREKGWTRFRHFTDDGISGTTFDRPSFKAMIQLVEDGEVETIIL
KDMSRLGRDYLVVGQLREFFRKKGVRLIAINDNHDSYNGDDDFLVFRDVMNEMYAKDISKKIKSTFKSKGKSGKHVASVT
PYGYLKDENDGNHWIVDEEAAEIVRLIFKWTIDGLGPYQIAKLLQEKKVEIPAVHMARFGQGNNRNKKVKDPYGWGSSTV
VGILKKREYLGHTVNFKTQKHFKDKKSHYVSEDNWVIFENTQEPIIDQQTFDTVQKLRENVRRYPDGWGEHHVLTGLMYC
ADCGAKMYVHRTSNGKRIAQYTCSAYTKVPCGTLCKTQHRINESVVLELIGDTLRAIFEYAKYDRSEFIDTITMAQSTQE
DAEVKKVRARIAVAGNRCEELEKLICRIYEDNILGKLPDSRYEVLDKQYAREKAELDAEIKELEAKLTEYEKSRNSAGKF
IALIDKYEKFEELTPAMVNEFVDKVLVHERDRKGSIQTTQEIEIYFNFVGRYVPPAMMTEPTAEEQAEIDRINRIKDRRH
QQYLRRKESGWQRKYEERVKNEKRAKMQAMKEEIRRQDRENGVYATAGSLALEPTIGMPE

Sequences:

>Translated_620_residues
MSSEKIIVLYERLSREDENLGESYSISNQKKLLEDYCREKGWTRFRHFTDDGISGTTFDRPSFKAMIQLVEDGEVETIIL
KDMSRLGRDYLVVGQLREFFRKKGVRLIAINDNHDSYNGDDDFLVFRDVMNEMYAKDISKKIKSTFKSKGKSGKHVASVT
PYGYLKDENDGNHWIVDEEAAEIVRLIFKWTIDGLGPYQIAKLLQEKKVEIPAVHMARFGQGNNRNKKVKDPYGWGSSTV
VGILKKREYLGHTVNFKTQKHFKDKKSHYVSEDNWVIFENTQEPIIDQQTFDTVQKLRENVRRYPDGWGEHHVLTGLMYC
ADCGAKMYVHRTSNGKRIAQYTCSAYTKVPCGTLCKTQHRINESVVLELIGDTLRAIFEYAKYDRSEFIDTITMAQSTQE
DAEVKKVRARIAVAGNRCEELEKLICRIYEDNILGKLPDSRYEVLDKQYAREKAELDAEIKELEAKLTEYEKSRNSAGKF
IALIDKYEKFEELTPAMVNEFVDKVLVHERDRKGSIQTTQEIEIYFNFVGRYVPPAMMTEPTAEEQAEIDRINRIKDRRH
QQYLRRKESGWQRKYEERVKNEKRAKMQAMKEEIRRQDRENGVYATAGSLALEPTIGMPE
>Mature_619_residues
SSEKIIVLYERLSREDENLGESYSISNQKKLLEDYCREKGWTRFRHFTDDGISGTTFDRPSFKAMIQLVEDGEVETIILK
DMSRLGRDYLVVGQLREFFRKKGVRLIAINDNHDSYNGDDDFLVFRDVMNEMYAKDISKKIKSTFKSKGKSGKHVASVTP
YGYLKDENDGNHWIVDEEAAEIVRLIFKWTIDGLGPYQIAKLLQEKKVEIPAVHMARFGQGNNRNKKVKDPYGWGSSTVV
GILKKREYLGHTVNFKTQKHFKDKKSHYVSEDNWVIFENTQEPIIDQQTFDTVQKLRENVRRYPDGWGEHHVLTGLMYCA
DCGAKMYVHRTSNGKRIAQYTCSAYTKVPCGTLCKTQHRINESVVLELIGDTLRAIFEYAKYDRSEFIDTITMAQSTQED
AEVKKVRARIAVAGNRCEELEKLICRIYEDNILGKLPDSRYEVLDKQYAREKAELDAEIKELEAKLTEYEKSRNSAGKFI
ALIDKYEKFEELTPAMVNEFVDKVLVHERDRKGSIQTTQEIEIYFNFVGRYVPPAMMTEPTAEEQAEIDRINRIKDRRHQ
QYLRRKESGWQRKYEERVKNEKRAKMQAMKEEIRRQDRENGVYATAGSLALEPTIGMPE

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 72209; Mature: 72078

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEKIIVLYERLSREDENLGESYSISNQKKLLEDYCREKGWTRFRHFTDDGISGTTFDR
CCCCCEEEEEHHHCCCHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
PSFKAMIQLVEDGEVETIILKDMSRLGRDYLVVGQLREFFRKKGVRLIAINDNHDSYNGD
HHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
DDFLVFRDVMNEMYAKDISKKIKSTFKSKGKSGKHVASVTPYGYLKDENDGNHWIVDEEA
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCEEEECHHH
AEIVRLIFKWTIDGLGPYQIAKLLQEKKVEIPAVHMARFGQGNNRNKKVKDPYGWGSSTV
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHH
VGILKKREYLGHTVNFKTQKHFKDKKSHYVSEDNWVIFENTQEPIIDQQTFDTVQKLREN
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VRRYPDGWGEHHVLTGLMYCADCGAKMYVHRTSNGKRIAQYTCSAYTKVPCGTLCKTQHR
HHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCHHHHHHHHH
INESVVLELIGDTLRAIFEYAKYDRSEFIDTITMAQSTQEDAEVKKVRARIAVAGNRCEE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHH
LEKLICRIYEDNILGKLPDSRYEVLDKQYAREKAELDAEIKELEAKLTEYEKSRNSAGKF
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IALIDKYEKFEELTPAMVNEFVDKVLVHERDRKGSIQTTQEIEIYFNFVGRYVPPAMMTE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCC
PTAEEQAEIDRINRIKDRRHQQYLRRKESGWQRKYEERVKNEKRAKMQAMKEEIRRQDRE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGVYATAGSLALEPTIGMPE
CCEEEECCCEEECCCCCCCC
>Mature Secondary Structure 
SSEKIIVLYERLSREDENLGESYSISNQKKLLEDYCREKGWTRFRHFTDDGISGTTFDR
CCCCEEEEEHHHCCCHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
PSFKAMIQLVEDGEVETIILKDMSRLGRDYLVVGQLREFFRKKGVRLIAINDNHDSYNGD
HHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
DDFLVFRDVMNEMYAKDISKKIKSTFKSKGKSGKHVASVTPYGYLKDENDGNHWIVDEEA
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCCCEEEECHHH
AEIVRLIFKWTIDGLGPYQIAKLLQEKKVEIPAVHMARFGQGNNRNKKVKDPYGWGSSTV
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHH
VGILKKREYLGHTVNFKTQKHFKDKKSHYVSEDNWVIFENTQEPIIDQQTFDTVQKLREN
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VRRYPDGWGEHHVLTGLMYCADCGAKMYVHRTSNGKRIAQYTCSAYTKVPCGTLCKTQHR
HHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCHHHHHHHHH
INESVVLELIGDTLRAIFEYAKYDRSEFIDTITMAQSTQEDAEVKKVRARIAVAGNRCEE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHH
LEKLICRIYEDNILGKLPDSRYEVLDKQYAREKAELDAEIKELEAKLTEYEKSRNSAGKF
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IALIDKYEKFEELTPAMVNEFVDKVLVHERDRKGSIQTTQEIEIYFNFVGRYVPPAMMTE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCC
PTAEEQAEIDRINRIKDRRHQQYLRRKESGWQRKYEERVKNEKRAKMQAMKEEIRRQDRE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGVYATAGSLALEPTIGMPE
CCEEEECCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]