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The map label for this gene is macB [H]

Identifier: 238925897

GI number: 238925897

Start: 3317145

End: 3318329

Strand: Reverse

Name: macB [H]

Synonym: EUBREC_3555

Alternate gene names: 238925897

Gene position: 3318329-3317145 (Counterclockwise)

Preceding gene: 238925898

Following gene: 238925896

Centisome position: 96.19

GC content: 42.78

Gene sequence:

>1185_bases
ATGATACTTAAAGACCTTCGTCTGTCTCCACTTAGAAGTATTCTGACAAGTGTTTCAATGCTTGTAGGCATTATCGCAAT
GCTTGGATCGGTATTAGTTGGTACGCTTGGACGGGAGTATTTGATTTCCGTAAACGCACAGGTATATGGCTGGTCACCTA
CTTACTCATTCGTGATAACGGAATCCGATTTTCACGATAGAAATAAAATGGAACAATTATTCCAGAGATTTGAAGCCATT
GATGATGTAGCCGCTGTTACTTTTTCTATGGGAGAAGATATTCGATTTGCACCAATGAAAGATTTAACGCCAATACCGCC
GAATGATGTTTACCAAAACCTGATGGCTTTTGATTTAGTTTGCACCACGGAGGCATATAGTCAAGTCTATAATCTTCCAA
TGACATCCGGTAGATGGTTAGAGCCTTCGAGTGAGGGCGGCTCGCTTGAAGTGGTCATAAACAAAGAAGCTAAAAACTAT
TTTAATGATTCGCCCTATGCTGCAGGAAATGTAAAAAGCACACTTTCGTTAACCCCATTCAATATTGTCGGAGTAGTAAA
CGATGGCAGGGATTTTCCGACTATCTATGCGGATTCTGCGGCGATCCTCAATTTCGCACCAGCAATGTGGCAAGTACAAA
ATGCAAATGTGTATTGGCATCCCACAACAGGACTGACAATCGAACAGATACATTCTGCCCTTGGCGACATTTTGACTGAT
ACCATTGGCGGTTACTGGGAAAGTGCTGGGCGGAGTGATATTGGAGATACCTATGATTCGGTATTGTCCATACTGCAATT
AGGGCTTTTGGTTACTTCGCTTTTGTTGCTGTTTGTTTCCGTATTAGGGCAGATCAATATCGGACTATCTTCATTGGAAC
AGCGCACACATGAGTTGCTGATCCGCAGAGCGATAGGTGCTTCACGAACAAATATTGTGGCATTGGTTTTAGGCTCACAG
TTGATTTTATCAATATTCGTTTGCCTTGCAGCTATTTTGATTTCGCTGATTTTGGTGCATTGTATTGGAGCGTTGCTCCC
TGTGGATTCCCCGGTGGGAACACCGAGTTATCCAATCAGCGTTGCTGTTGTTGCAGTTGCTGTGTCTGTGCTTACAGCAT
TATTGGGCGGATTATTACCAGCATTGAAAGCAGCAAAATTAGAGCCTGCATTGGCTCTTAGATAA

Upstream 100 bases:

>100_bases
AATGGAATTATGCTGCTGTTGGTTACGCACGATCCTGATATTGCAGATACCTGTGATACGATTTTTGAAATGGATGGAGG
GAGGATAACTTGTGCTAAAA

Downstream 100 bases:

>100_bases
TAAAACTCAATTCAAGGAGGAAACAAAATGAAACGAACAATCTCAAAATCCGAAAGACCGTACAGACTGTTATTGTGTGT
TATGATTTCTTTGCTGGTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MILKDLRLSPLRSILTSVSMLVGIIAMLGSVLVGTLGREYLISVNAQVYGWSPTYSFVITESDFHDRNKMEQLFQRFEAI
DDVAAVTFSMGEDIRFAPMKDLTPIPPNDVYQNLMAFDLVCTTEAYSQVYNLPMTSGRWLEPSSEGGSLEVVINKEAKNY
FNDSPYAAGNVKSTLSLTPFNIVGVVNDGRDFPTIYADSAAILNFAPAMWQVQNANVYWHPTTGLTIEQIHSALGDILTD
TIGGYWESAGRSDIGDTYDSVLSILQLGLLVTSLLLLFVSVLGQINIGLSSLEQRTHELLIRRAIGASRTNIVALVLGSQ
LILSIFVCLAAILISLILVHCIGALLPVDSPVGTPSYPISVAVVAVAVSVLTALLGGLLPALKAAKLEPALALR

Sequences:

>Translated_394_residues
MILKDLRLSPLRSILTSVSMLVGIIAMLGSVLVGTLGREYLISVNAQVYGWSPTYSFVITESDFHDRNKMEQLFQRFEAI
DDVAAVTFSMGEDIRFAPMKDLTPIPPNDVYQNLMAFDLVCTTEAYSQVYNLPMTSGRWLEPSSEGGSLEVVINKEAKNY
FNDSPYAAGNVKSTLSLTPFNIVGVVNDGRDFPTIYADSAAILNFAPAMWQVQNANVYWHPTTGLTIEQIHSALGDILTD
TIGGYWESAGRSDIGDTYDSVLSILQLGLLVTSLLLLFVSVLGQINIGLSSLEQRTHELLIRRAIGASRTNIVALVLGSQ
LILSIFVCLAAILISLILVHCIGALLPVDSPVGTPSYPISVAVVAVAVSVLTALLGGLLPALKAAKLEPALALR
>Mature_394_residues
MILKDLRLSPLRSILTSVSMLVGIIAMLGSVLVGTLGREYLISVNAQVYGWSPTYSFVITESDFHDRNKMEQLFQRFEAI
DDVAAVTFSMGEDIRFAPMKDLTPIPPNDVYQNLMAFDLVCTTEAYSQVYNLPMTSGRWLEPSSEGGSLEVVINKEAKNY
FNDSPYAAGNVKSTLSLTPFNIVGVVNDGRDFPTIYADSAAILNFAPAMWQVQNANVYWHPTTGLTIEQIHSALGDILTD
TIGGYWESAGRSDIGDTYDSVLSILQLGLLVTSLLLLFVSVLGQINIGLSSLEQRTHELLIRRAIGASRTNIVALVLGSQ
LILSIFVCLAAILISLILVHCIGALLPVDSPVGTPSYPISVAVVAVAVSVLTALLGGLLPALKAAKLEPALALR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42535; Mature: 42535

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKDLRLSPLRSILTSVSMLVGIIAMLGSVLVGTLGREYLISVNAQVYGWSPTYSFVIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCEEEEEE
ESDFHDRNKMEQLFQRFEAIDDVAAVTFSMGEDIRFAPMKDLTPIPPNDVYQNLMAFDLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHH
CTTEAYSQVYNLPMTSGRWLEPSSEGGSLEVVINKEAKNYFNDSPYAAGNVKSTLSLTPF
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCEEEECCE
NIVGVVNDGRDFPTIYADSAAILNFAPAMWQVQNANVYWHPTTGLTIEQIHSALGDILTD
EEEEEEECCCCCCEEEECCHHHHHHCHHHEEEECCEEEEECCCCCCHHHHHHHHHHHHHH
TIGGYWESAGRSDIGDTYDSVLSILQLGLLVTSLLLLFVSVLGQINIGLSSLEQRTHELL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRRAIGASRTNIVALVLGSQLILSIFVCLAAILISLILVHCIGALLPVDSPVGTPSYPIS
HHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VAVVAVAVSVLTALLGGLLPALKAAKLEPALALR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MILKDLRLSPLRSILTSVSMLVGIIAMLGSVLVGTLGREYLISVNAQVYGWSPTYSFVIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCEEEEEE
ESDFHDRNKMEQLFQRFEAIDDVAAVTFSMGEDIRFAPMKDLTPIPPNDVYQNLMAFDLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHH
CTTEAYSQVYNLPMTSGRWLEPSSEGGSLEVVINKEAKNYFNDSPYAAGNVKSTLSLTPF
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCEEEECCE
NIVGVVNDGRDFPTIYADSAAILNFAPAMWQVQNANVYWHPTTGLTIEQIHSALGDILTD
EEEEEEECCCCCCEEEECCHHHHHHCHHHEEEECCEEEEECCCCCCHHHHHHHHHHHHHH
TIGGYWESAGRSDIGDTYDSVLSILQLGLLVTSLLLLFVSVLGQINIGLSSLEQRTHELL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IRRAIGASRTNIVALVLGSQLILSIFVCLAAILISLILVHCIGALLPVDSPVGTPSYPIS
HHHHHCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VAVVAVAVSVLTALLGGLLPALKAAKLEPALALR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA