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The map label for this gene is dinB [H]

Identifier: 238925884

GI number: 238925884

Start: 3307653

End: 3308870

Strand: Reverse

Name: dinB [H]

Synonym: EUBREC_3542

Alternate gene names: 238925884

Gene position: 3308870-3307653 (Counterclockwise)

Preceding gene: 238925887

Following gene: 238925882

Centisome position: 95.92

GC content: 40.64

Gene sequence:

>1218_bases
ATGAACTGTTTTTATGCCAGTGTAGAAATGCTACATCATCCGGAATTTGCTGGAATGCCTCTGGCAGTCGGTGGTGATCC
GGAAGCCCGGCATGGAATTGTGCTGACAGCAAATTATATTGCCAAGAAAAAAGGAGTAAAAACCGGAATGGCATTATGGC
AGGCGAAACAGGTTTGCCCGGAAATTATTTTTGTACCACCACGGATGGATTTATATTTGCGATTTTCTCAAATGGCAAGG
GAAATCTATTCAGAGTATACAGATAAAATTGAGCCATATGGAATTGATGAAGCCTGGCTGGATGTATCAGATAGTGGAAA
TCTGAAAGGAAGCGGAATGACGATTGCGAGAGAAATCAGCCATCGGATTAAATACGAACTTGGAGTAACAGTGAGTATTG
GAATTTCCTGGAATAAGATTTATGCGAAACTTGGTTCAGATTACAAAAAGCCGGATGCAATCACAGAGTTTAATCGAGAA
AATTATAAAGACAGGATATGGCAGCTTCCTGCGTCAGATTTGCTTTATGTCGGAAGACAGACAAATAAGAAATTGCAAAA
ACTTGGAATCCGGACAATCGGGCAACTTGCGGAATCAGACGAAAAGTTGTTAGAGAGCCATTTTGGAAAAATAGGAAATG
TATTATGGGCTTTCGCAAATGGCTGGGATGAAGATCCGGTTTGCAAGGAAGGGTATGAAGCTCCAGTAAAGTCGATAGGT
AATAGCACCACAACACCGAGAGATCTGGAAAATGATCTGGATGTTTGGATCATTCAAATAGCATTGGCAGAAAGTGTAGC
TGCACGATTGCGGAAACATGGATTTAAATGCAAAACAGTAGAAATTACAGTTCGAGATAATGGATTGTATAGTTTTTCCA
GACAGATACATTTACGACAGCCAACGAATATTACAAATGAGATTGTAACTGCAGCATTTCAGCTATTTAAAGATAATTAC
AAATGGGAACATCCCATTAGAAGCCTGGGAATCCGAGCTGCGGATCTTGTGTTAGATGATATTCCCGTGCAGTTGGATTT
ATTTGGAAATCAGGAGAAAAAAGAAAAGTTAGAGAAGCTGGATCGTACTGTAGATGAGATAAGACGACGGTTTGGATATT
TCAGTATACAGCGAGCGGCAATGTACCAGGATAAAGTCTTATCCCACTTAGACGCTGGTACGCACACGGTCCATCCACAC
AGTTATTTTCATGGGTAA

Upstream 100 bases:

>100_bases
TCGATATATACTAAACATACAGAAATTGATAAGACATTATGTTGAAGGAAGCAGCTGGGAGGTGAAAAGTTTGAGTGAGC
GTGTGATCCTGCATAGTGAT

Downstream 100 bases:

>100_bases
TTGGAGGGATAGATTTGAAAAAAGCATTAACCAGAAAACAGGAAGAAAGTTATCAGTGTATTTTGAATTATACGAAGGAG
CATGGATATCCGCCGACAGT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MNCFYASVEMLHHPEFAGMPLAVGGDPEARHGIVLTANYIAKKKGVKTGMALWQAKQVCPEIIFVPPRMDLYLRFSQMAR
EIYSEYTDKIEPYGIDEAWLDVSDSGNLKGSGMTIAREISHRIKYELGVTVSIGISWNKIYAKLGSDYKKPDAITEFNRE
NYKDRIWQLPASDLLYVGRQTNKKLQKLGIRTIGQLAESDEKLLESHFGKIGNVLWAFANGWDEDPVCKEGYEAPVKSIG
NSTTTPRDLENDLDVWIIQIALAESVAARLRKHGFKCKTVEITVRDNGLYSFSRQIHLRQPTNITNEIVTAAFQLFKDNY
KWEHPIRSLGIRAADLVLDDIPVQLDLFGNQEKKEKLEKLDRTVDEIRRRFGYFSIQRAAMYQDKVLSHLDAGTHTVHPH
SYFHG

Sequences:

>Translated_405_residues
MNCFYASVEMLHHPEFAGMPLAVGGDPEARHGIVLTANYIAKKKGVKTGMALWQAKQVCPEIIFVPPRMDLYLRFSQMAR
EIYSEYTDKIEPYGIDEAWLDVSDSGNLKGSGMTIAREISHRIKYELGVTVSIGISWNKIYAKLGSDYKKPDAITEFNRE
NYKDRIWQLPASDLLYVGRQTNKKLQKLGIRTIGQLAESDEKLLESHFGKIGNVLWAFANGWDEDPVCKEGYEAPVKSIG
NSTTTPRDLENDLDVWIIQIALAESVAARLRKHGFKCKTVEITVRDNGLYSFSRQIHLRQPTNITNEIVTAAFQLFKDNY
KWEHPIRSLGIRAADLVLDDIPVQLDLFGNQEKKEKLEKLDRTVDEIRRRFGYFSIQRAAMYQDKVLSHLDAGTHTVHPH
SYFHG
>Mature_405_residues
MNCFYASVEMLHHPEFAGMPLAVGGDPEARHGIVLTANYIAKKKGVKTGMALWQAKQVCPEIIFVPPRMDLYLRFSQMAR
EIYSEYTDKIEPYGIDEAWLDVSDSGNLKGSGMTIAREISHRIKYELGVTVSIGISWNKIYAKLGSDYKKPDAITEFNRE
NYKDRIWQLPASDLLYVGRQTNKKLQKLGIRTIGQLAESDEKLLESHFGKIGNVLWAFANGWDEDPVCKEGYEAPVKSIG
NSTTTPRDLENDLDVWIIQIALAESVAARLRKHGFKCKTVEITVRDNGLYSFSRQIHLRQPTNITNEIVTAAFQLFKDNY
KWEHPIRSLGIRAADLVLDDIPVQLDLFGNQEKKEKLEKLDRTVDEIRRRFGYFSIQRAAMYQDKVLSHLDAGTHTVHPH
SYFHG

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=411, Percent_Identity=25.7907542579075, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI7706681, Length=412, Percent_Identity=25.7281553398058, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI154350220, Length=322, Percent_Identity=26.3975155279503, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI5729982, Length=346, Percent_Identity=25.4335260115607, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI7705344, Length=103, Percent_Identity=36.8932038834951, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786425, Length=251, Percent_Identity=38.2470119521912, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1787432, Length=403, Percent_Identity=24.8138957816377, Blast_Score=101, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193205700, Length=104, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17537959, Length=234, Percent_Identity=23.9316239316239, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19923006, Length=402, Percent_Identity=23.6318407960199, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46196; Mature: 46196

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCFYASVEMLHHPEFAGMPLAVGGDPEARHGIVLTANYIAKKKGVKTGMALWQAKQVCP
CCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHCCC
EIIFVPPRMDLYLRFSQMAREIYSEYTDKIEPYGIDEAWLDVSDSGNLKGSGMTIAREIS
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCHHHHHHH
HRIKYELGVTVSIGISWNKIYAKLGSDYKKPDAITEFNRENYKDRIWQLPASDLLYVGRQ
HHHEEEECEEEEECCCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCCHHHHEECCCH
TNKKLQKLGIRTIGQLAESDEKLLESHFGKIGNVLWAFANGWDEDPVCKEGYEAPVKSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
NSTTTPRDLENDLDVWIIQIALAESVAARLRKHGFKCKTVEITVRDNGLYSFSRQIHLRQ
CCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEEEEEEECC
PTNITNEIVTAAFQLFKDNYKWEHPIRSLGIRAADLVLDDIPVQLDLFGNQEKKEKLEKL
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHH
DRTVDEIRRRFGYFSIQRAAMYQDKVLSHLDAGTHTVHPHSYFHG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNCFYASVEMLHHPEFAGMPLAVGGDPEARHGIVLTANYIAKKKGVKTGMALWQAKQVCP
CCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHCCC
EIIFVPPRMDLYLRFSQMAREIYSEYTDKIEPYGIDEAWLDVSDSGNLKGSGMTIAREIS
CEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCHHHHHHH
HRIKYELGVTVSIGISWNKIYAKLGSDYKKPDAITEFNRENYKDRIWQLPASDLLYVGRQ
HHHEEEECEEEEECCCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHCCCHHHHEECCCH
TNKKLQKLGIRTIGQLAESDEKLLESHFGKIGNVLWAFANGWDEDPVCKEGYEAPVKSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
NSTTTPRDLENDLDVWIIQIALAESVAARLRKHGFKCKTVEITVRDNGLYSFSRQIHLRQ
CCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEEEEEEECC
PTNITNEIVTAAFQLFKDNYKWEHPIRSLGIRAADLVLDDIPVQLDLFGNQEKKEKLEKL
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHH
DRTVDEIRRRFGYFSIQRAAMYQDKVLSHLDAGTHTVHPHSYFHG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA