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The map label for this gene is 238925776

Identifier: 238925776

GI number: 238925776

Start: 3230995

End: 3232380

Strand: Reverse

Name: 238925776

Synonym: EUBREC_3433

Alternate gene names: NA

Gene position: 3232380-3230995 (Counterclockwise)

Preceding gene: 238925777

Following gene: 238925775

Centisome position: 93.7

GC content: 35.71

Gene sequence:

>1386_bases
ATGGCTCAAAGAACAGTGGCATTATGTGATGGAAAATTTATAGGAATTGAATCAATTTATACCGTCATAGATGGTAAACA
AATTAATATTCCGGACAAACTTGAACAGCTTCGAGCAAAAAGCCGTAATAATGAGTTGTTCTGTCCTTGTGGCTGTGGAG
CAAATCTTGTACTGGTGGCAGGTGAACGAAATTTAAGAGAACAGCATTTTAGAATAAAAGAGGGTTTTGATGGTATATGT
CAGATGCCCGTTGAAGGAATTAATTCAATTGATTCAAAGATTGCTCTAAAATGTTGGCTGGAGGATAAACTGCATACAGA
TGATATTGAAAGCAGGGTTCCTATAAGAACTGTATCTGAGTCTGAAAGAAAATATGAATTTACATTTATGTCAGCGAAAA
AGAAGGTAGCTTTATCTTTTTGCAATGAATACCGTAATTTATCTGATGATAAATTTACTATTCTTGAACAGCATAGCAAT
GGTAATTCAATTATTTATGTTGCGTCAGGGGATAAATCCGAAACAAATGGACAGTACCCGGAAGGGTTAATGAAAATTCA
GAAGAGACAGGGCTATTGCCTGCTTTTAAATGTAGATGGAGCTGATTATTCAAAGGCTGAGTTGACAGTTGTATATTATG
AAAAAAATGCTGATGGAGTATGGGAAAAAGTCAATATAGCAAGAGATAAATTAAGTAAATTTGACATATCAGATTCATCA
CAGATAATGTATCATAATCATTCGCTGTCTGATATGTTAAAGGAAAAACAACTGGAGTTTAATAAGCATAAGCAGGCAAT
TATTTATCAGCGTGAGTTGGATAAGATACATGCTGAAGAAGCCTGGAGAGCTGACGAGGAACGAAGAAAACAGGCTAGAA
TAAAAGCTGAAAAAGATAGAAAGGCAGAACTTGAGCGTAGAGAAAAAGAAAGAATAGAGCAGGAAAAAATTGCTGCTGAG
AAAAAAGAACAAGCCCGAATGGAACAAGAAAGAGTTGAGGTTGAAAAAAGACAGAAGAGACAGGAATTCCTAAAAGTCAT
AAATAGTGGTGATTGTCCGGAAGATAGGGTTTTAACTGATGAAGGAGGACGCAGATGGGTACTGTGCGAGTTCTGTGGAA
AATTTGCTCCGGCAAGTGCATTTGCTTCATATGGTGGTTTCGGAAAATTAAATAAAGGGAAGTGCTATGAATGCTCAAGA
AATCCGAATATAAATACAGAAGTAAATGTCTCAGAGGAAAAAGCAAGACAAAAGCAAAGATATGATCCTAATATATGTCC
TGAATGTGGTGGACGTTTGCGATTAATACAAGGTCCTTTTGGTAAATTTATGGGATGCGAGAATTATCCTACGTGTAAAT
TTAATAGAAGAGTAAGAAAAAAATAG

Upstream 100 bases:

>100_bases
TTATAGGGCTATGGACTATTATCAGAGGAGATATAGGCAGTCACAGGAAGATGGAGAAGTATAATGTAAACTTATGAAGC
AGTTAGGGGGATGAAATCAT

Downstream 100 bases:

>100_bases
GAACGTTAGAGTTCGAACTGTGCTTATTGTTTTGTATAGAGGGAAAATTAAATGGCTGATTCGAATGTACAAATTGAAGA
AGTATATAAAAGAGTACCAT

Product: DNA topoisomerase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MAQRTVALCDGKFIGIESIYTVIDGKQINIPDKLEQLRAKSRNNELFCPCGCGANLVLVAGERNLREQHFRIKEGFDGIC
QMPVEGINSIDSKIALKCWLEDKLHTDDIESRVPIRTVSESERKYEFTFMSAKKKVALSFCNEYRNLSDDKFTILEQHSN
GNSIIYVASGDKSETNGQYPEGLMKIQKRQGYCLLLNVDGADYSKAELTVVYYEKNADGVWEKVNIARDKLSKFDISDSS
QIMYHNHSLSDMLKEKQLEFNKHKQAIIYQRELDKIHAEEAWRADEERRKQARIKAEKDRKAELERREKERIEQEKIAAE
KKEQARMEQERVEVEKRQKRQEFLKVINSGDCPEDRVLTDEGGRRWVLCEFCGKFAPASAFASYGGFGKLNKGKCYECSR
NPNINTEVNVSEEKARQKQRYDPNICPECGGRLRLIQGPFGKFMGCENYPTCKFNRRVRKK

Sequences:

>Translated_461_residues
MAQRTVALCDGKFIGIESIYTVIDGKQINIPDKLEQLRAKSRNNELFCPCGCGANLVLVAGERNLREQHFRIKEGFDGIC
QMPVEGINSIDSKIALKCWLEDKLHTDDIESRVPIRTVSESERKYEFTFMSAKKKVALSFCNEYRNLSDDKFTILEQHSN
GNSIIYVASGDKSETNGQYPEGLMKIQKRQGYCLLLNVDGADYSKAELTVVYYEKNADGVWEKVNIARDKLSKFDISDSS
QIMYHNHSLSDMLKEKQLEFNKHKQAIIYQRELDKIHAEEAWRADEERRKQARIKAEKDRKAELERREKERIEQEKIAAE
KKEQARMEQERVEVEKRQKRQEFLKVINSGDCPEDRVLTDEGGRRWVLCEFCGKFAPASAFASYGGFGKLNKGKCYECSR
NPNINTEVNVSEEKARQKQRYDPNICPECGGRLRLIQGPFGKFMGCENYPTCKFNRRVRKK
>Mature_460_residues
AQRTVALCDGKFIGIESIYTVIDGKQINIPDKLEQLRAKSRNNELFCPCGCGANLVLVAGERNLREQHFRIKEGFDGICQ
MPVEGINSIDSKIALKCWLEDKLHTDDIESRVPIRTVSESERKYEFTFMSAKKKVALSFCNEYRNLSDDKFTILEQHSNG
NSIIYVASGDKSETNGQYPEGLMKIQKRQGYCLLLNVDGADYSKAELTVVYYEKNADGVWEKVNIARDKLSKFDISDSSQ
IMYHNHSLSDMLKEKQLEFNKHKQAIIYQRELDKIHAEEAWRADEERRKQARIKAEKDRKAELERREKERIEQEKIAAEK
KEQARMEQERVEVEKRQKRQEFLKVINSGDCPEDRVLTDEGGRRWVLCEFCGKFAPASAFASYGGFGKLNKGKCYECSRN
PNINTEVNVSEEKARQKQRYDPNICPECGGRLRLIQGPFGKFMGCENYPTCKFNRRVRKK

Specific function: Unknown

COG id: COG1754

COG function: function code R; Uncharacterized C-terminal domain of topoisomerase IA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 53302; Mature: 53171

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRTVALCDGKFIGIESIYTVIDGKQINIPDKLEQLRAKSRNNELFCPCGCGANLVLVA
CCCCEEEEECCCEECHHHHHHHCCCCEECCHHHHHHHHHHCCCCCEEEECCCCCCEEEEE
GERNLREQHFRIKEGFDGICQMPVEGINSIDSKIALKCWLEDKLHTDDIESRVPIRTVSE
CCCCHHHHHHHHHCCCCHHHHCCHHHHHHHCHHEEEEEEECCCCCCCCHHCCCCEEECCC
SERKYEFTFMSAKKKVALSFCNEYRNLSDDKFTILEQHSNGNSIIYVASGDKSETNGQYP
CCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCC
EGLMKIQKRQGYCLLLNVDGADYSKAELTVVYYEKNADGVWEKVNIARDKLSKFDISDSS
HHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
QIMYHNHSLSDMLKEKQLEFNKHKQAIIYQRELDKIHAEEAWRADEERRKQARIKAEKDR
EEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
KAELERREKERIEQEKIAAEKKEQARMEQERVEVEKRQKRQEFLKVINSGDCPEDRVLTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
EGGRRWVLCEFCGKFAPASAFASYGGFGKLNKGKCYECSRNPNINTEVNVSEEKARQKQR
CCCCEEEEHHHHCCCCCHHHHHHCCCCCCCCCCCCEECCCCCCCCCEEECCHHHHHHHHC
YDPNICPECGGRLRLIQGPFGKFMGCENYPTCKFNRRVRKK
CCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
AQRTVALCDGKFIGIESIYTVIDGKQINIPDKLEQLRAKSRNNELFCPCGCGANLVLVA
CCCEEEEECCCEECHHHHHHHCCCCEECCHHHHHHHHHHCCCCCEEEECCCCCCEEEEE
GERNLREQHFRIKEGFDGICQMPVEGINSIDSKIALKCWLEDKLHTDDIESRVPIRTVSE
CCCCHHHHHHHHHCCCCHHHHCCHHHHHHHCHHEEEEEEECCCCCCCCHHCCCCEEECCC
SERKYEFTFMSAKKKVALSFCNEYRNLSDDKFTILEQHSNGNSIIYVASGDKSETNGQYP
CCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCC
EGLMKIQKRQGYCLLLNVDGADYSKAELTVVYYEKNADGVWEKVNIARDKLSKFDISDSS
HHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
QIMYHNHSLSDMLKEKQLEFNKHKQAIIYQRELDKIHAEEAWRADEERRKQARIKAEKDR
EEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
KAELERREKERIEQEKIAAEKKEQARMEQERVEVEKRQKRQEFLKVINSGDCPEDRVLTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
EGGRRWVLCEFCGKFAPASAFASYGGFGKLNKGKCYECSRNPNINTEVNVSEEKARQKQR
CCCCEEEEHHHHCCCCCHHHHHHCCCCCCCCCCCCEECCCCCCCCCEEECCHHHHHHHHC
YDPNICPECGGRLRLIQGPFGKFMGCENYPTCKFNRRVRKK
CCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA