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The map label for this gene is dinB [H]

Identifier: 238925756

GI number: 238925756

Start: 3218320

End: 3219345

Strand: Reverse

Name: dinB [H]

Synonym: EUBREC_3413

Alternate gene names: 238925756

Gene position: 3219345-3218320 (Counterclockwise)

Preceding gene: 238925759

Following gene: 238925755

Centisome position: 93.32

GC content: 37.91

Gene sequence:

>1026_bases
ATGCAGGAGGTGATGAAGATGGGAGACAGGGTAATACTTCATTCAGATATCAACTGTTGTTATGCCTCGATTGAGCATCT
GCATCATCCGGAGCTTGCAGGAAAGCCACTGGCGGTAGGCGGTGACCCGGAGGCAAGACATGGGATTGTCTTAACAGCTG
ACTATATTGCCAAGAAGTACGGTGTGAAAACAGGAATGGCACTCTGGCAGGCAAAGGAGGTCTGTCCGGACATAACATTT
GTATCACCAAGAATGGACTTATATCTTCGATTTTCAAGGATGGCTCATGAGATATATGCAGAATATACGGATAGACAGGA
GCCATATGGGATTGATGAGTGCTGGCTTGATGTGACAGGGAGCAGTTCCCTTAAAGGAGATGGATTGCTCATTGCACAGG
AAATCAGCAGGAGAATGAAGTCAGAGCTTGGAATTACAGTCAGTGTTGGTGTTTCTTTCAATAAGATATTTGCAAAGCTT
GGTTCAGACTATAAGAATGGATGCTATTTGATTCTCATACAGAATCGGTGTATGAAGCAGAAGTTTCTTGATTTGCCAGA
ACCATATAAAGAATATGACTTAAAGAAAGCAATTTTGAAAAATATGAAAAAATTTCTTCTTGAATTTGGAAGAGATTTTA
TTTTCATTGATGAAGAATATCATGTCCAAGTGGGAAATAATGATTACTATGTAGATCTTCTTTTTTATCACAGAGAGTTA
CAGTGTTTAGTTGCTATCGATCTAAAAATTGATGATTTCAAACCTGAATATATGGGAAAAATGGACTTTTATTTAGAGGC
ATTGGATAGAGATATTAAGAAGCCTCATGAAAATCCGAGTGTAGGAATGATTCTTTGTAAAAATGCTGATACGGATGTCG
TTGAATATTCTTTGAGTAGAAGTTTATCGCAGACAATGATTGCTGAATATAAAACTAAGTTGATTGATAAGAGTATTCTG
CAGAGAAAACTAGCTGAGTTATATGATATTGCAGAGGAAGAGGTGAAAAACTCTCAACAGGATTGA

Upstream 100 bases:

>100_bases
ATGTGTCCGTTGACAGTCGATTATTCTTGGGGTTATACTATGCCCTGTAAGAAACATTACTCATATACTTGTACTAAAGG
TTATGGTAATGACAGATTAA

Downstream 100 bases:

>100_bases
GAGTTTTGAAAATGTGAGAAATAGGGGTGTGATGTGATTGGAGAGATTGTTCAATCTTCAGACAATAGATGAATTTTTAT
TAGATATTACAGAAACTGCT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MQEVMKMGDRVILHSDINCCYASIEHLHHPELAGKPLAVGGDPEARHGIVLTADYIAKKYGVKTGMALWQAKEVCPDITF
VSPRMDLYLRFSRMAHEIYAEYTDRQEPYGIDECWLDVTGSSSLKGDGLLIAQEISRRMKSELGITVSVGVSFNKIFAKL
GSDYKNGCYLILIQNRCMKQKFLDLPEPYKEYDLKKAILKNMKKFLLEFGRDFIFIDEEYHVQVGNNDYYVDLLFYHREL
QCLVAIDLKIDDFKPEYMGKMDFYLEALDRDIKKPHENPSVGMILCKNADTDVVEYSLSRSLSQTMIAEYKTKLIDKSIL
QRKLAELYDIAEEEVKNSQQD

Sequences:

>Translated_341_residues
MQEVMKMGDRVILHSDINCCYASIEHLHHPELAGKPLAVGGDPEARHGIVLTADYIAKKYGVKTGMALWQAKEVCPDITF
VSPRMDLYLRFSRMAHEIYAEYTDRQEPYGIDECWLDVTGSSSLKGDGLLIAQEISRRMKSELGITVSVGVSFNKIFAKL
GSDYKNGCYLILIQNRCMKQKFLDLPEPYKEYDLKKAILKNMKKFLLEFGRDFIFIDEEYHVQVGNNDYYVDLLFYHREL
QCLVAIDLKIDDFKPEYMGKMDFYLEALDRDIKKPHENPSVGMILCKNADTDVVEYSLSRSLSQTMIAEYKTKLIDKSIL
QRKLAELYDIAEEEVKNSQQD
>Mature_341_residues
MQEVMKMGDRVILHSDINCCYASIEHLHHPELAGKPLAVGGDPEARHGIVLTADYIAKKYGVKTGMALWQAKEVCPDITF
VSPRMDLYLRFSRMAHEIYAEYTDRQEPYGIDECWLDVTGSSSLKGDGLLIAQEISRRMKSELGITVSVGVSFNKIFAKL
GSDYKNGCYLILIQNRCMKQKFLDLPEPYKEYDLKKAILKNMKKFLLEFGRDFIFIDEEYHVQVGNNDYYVDLLFYHREL
QCLVAIDLKIDDFKPEYMGKMDFYLEALDRDIKKPHENPSVGMILCKNADTDVVEYSLSRSLSQTMIAEYKTKLIDKSIL
QRKLAELYDIAEEEVKNSQQD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=206, Percent_Identity=29.6116504854369, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=33.9449541284404, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1786425, Length=164, Percent_Identity=40.8536585365854, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1789614, Length=153, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787432, Length=150, Percent_Identity=32, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39329; Mature: 39329

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEVMKMGDRVILHSDINCCYASIEHLHHPELAGKPLAVGGDPEARHGIVLTADYIAKKY
CCHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEHHHHHHHH
GVKTGMALWQAKEVCPDITFVSPRMDLYLRFSRMAHEIYAEYTDRQEPYGIDECWLDVTG
CCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECC
SSSLKGDGLLIAQEISRRMKSELGITVSVGVSFNKIFAKLGSDYKNGCYLILIQNRCMKQ
CCCCCCCCEEEHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCEEEEEECCHHHHH
KFLDLPEPYKEYDLKKAILKNMKKFLLEFGRDFIFIDEEYHVQVGNNDYYVDLLFYHREL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCEEEEEEEECCEE
QCLVAIDLKIDDFKPEYMGKMDFYLEALDRDIKKPHENPSVGMILCKNADTDVVEYSLSR
EEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHH
SLSQTMIAEYKTKLIDKSILQRKLAELYDIAEEEVKNSQQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQEVMKMGDRVILHSDINCCYASIEHLHHPELAGKPLAVGGDPEARHGIVLTADYIAKKY
CCHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEHHHHHHHH
GVKTGMALWQAKEVCPDITFVSPRMDLYLRFSRMAHEIYAEYTDRQEPYGIDECWLDVTG
CCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECC
SSSLKGDGLLIAQEISRRMKSELGITVSVGVSFNKIFAKLGSDYKNGCYLILIQNRCMKQ
CCCCCCCCEEEHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCEEEEEECCHHHHH
KFLDLPEPYKEYDLKKAILKNMKKFLLEFGRDFIFIDEEYHVQVGNNDYYVDLLFYHREL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCEEEEEEEECCEE
QCLVAIDLKIDDFKPEYMGKMDFYLEALDRDIKKPHENPSVGMILCKNADTDVVEYSLSR
EEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHH
SLSQTMIAEYKTKLIDKSILQRKLAELYDIAEEEVKNSQQD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA