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The map label for this gene is mepA [H]

Identifier: 238925681

GI number: 238925681

Start: 3158623

End: 3159921

Strand: Direct

Name: mepA [H]

Synonym: EUBREC_3338

Alternate gene names: 238925681

Gene position: 3158623-3159921 (Clockwise)

Preceding gene: 238925678

Following gene: 238925682

Centisome position: 91.56

GC content: 42.8

Gene sequence:

>1299_bases
ATGAAAAAATTATTTGTAAAATATGTCTCACAAAACATACTCGGCATGGTGGGTATGTCATTATATATACTTGCCGACAC
CTTCTTTATATCAAAGGCGGTCGGCTCAAACGGTATCACCGCGCTCAATCTGGTGCTGCCTGTATACAATTTGATTTTTG
CCATAGGCGCAATGATCGGAGTCGGCTCCGCTATCAGATATGTCGTAGAGAAAAATAAGGGCGACACATCCAGCGAGAGC
TACTTTTTTCATGCCCTGCTGTGGTGTATTATAATAAGCGTTATATTCATATTGATTGGTATTTTCATCCCGGACAGGCT
CGTAGGGCTGCTCGGCGGAGATTCGGCAATTATAAATACCGGTAAAAACTATACACGTATTTTCATGCTTTTTACACCGT
TTTTCATGTGCAACTATGTGTGCAACGCTTTCGTAAGAAATGATGGCGCACCATCCATTGCCATGTGTGCCACACTTTTC
AGCAGCCTTTTTAATATTGTTTTTGATTACATACTCATGTTCCCGCTTGGACTTGGTATGGAGGGAGCCGCTTTAGCTAC
CGCTATTTCACCGATTATAGGCATCATGATATGCTGTATTCATTTCTGCTCAGACAAATGCTCCGTAAAGCTTAAGCCGA
CGGTTCCATCTGTCAAGAGACTCTTTTACTCCTGCCAGGTTGGTGTTTCTTCCTTTGTTGCTGAAATATCATCAGGTGTC
ATAACTATTGTCTTCAATATGATTATCCTGAGGCTTGCAGGAAATATCGGCGTGGCAGCATACGGTGTGGTTGCCAATAC
GTCACTGGTCGCTGTAGCTTTGTTCAACGGAATAGCACAGGGTTCACAGCCTCTTATCAGCGACTATTACGGCAAAGGAC
TTAGAAAAAATGTAGGTTCGATACTCAGGATGGCTGTCGTTTCATCTCTCTTAATTGCTGCACTGCTCATTTTGTTCATA
TGCACCTTTGCACCTTTTGTGACATCTGTTTTCAACAGCGAGCACGATGCCAGGCTTGCTTCGTATGCCGAGAGCGGACT
GCGCCTTTACTTTACAGGCTTTATTTTTGCCGGAATCAATATAGTAGGTTCTGCTATCCTAAGTGCCGTTGAGTCCGTAA
AATATGCGTTCGCGGCATCTATCATGCGTGGTTTTATCGCTATAAGCATTTTCGCATTCGCACTTTCAGCCGCTTTCGGC
ATGACAGGTGTGTGGCTTGCTTTTCCGGCAGCTGAATTTGTGACTATGTTTATTATTGTTAAGGGATTAAGAAAAAACTA
TTCTAATTATAATAGATAA

Upstream 100 bases:

>100_bases
ATTTCAATAGTCAAAAGGTCTCATTTTGAAACTTTTTACATCCGGGCTAATCAAAAATATCATTGATTTAAATGACAGAT
GCATTTACAATATAGCTATT

Downstream 100 bases:

>100_bases
ATTTTTTTCAAAAGCATTCGTTATGTTGGAAATCAAACATACAAGTTGTTTTTATAACGCTATTATTCTATCAGAAACAT
AAAAAACTACTGATGGAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKKLFVKYVSQNILGMVGMSLYILADTFFISKAVGSNGITALNLVLPVYNLIFAIGAMIGVGSAIRYVVEKNKGDTSSES
YFFHALLWCIIISVIFILIGIFIPDRLVGLLGGDSAIINTGKNYTRIFMLFTPFFMCNYVCNAFVRNDGAPSIAMCATLF
SSLFNIVFDYILMFPLGLGMEGAALATAISPIIGIMICCIHFCSDKCSVKLKPTVPSVKRLFYSCQVGVSSFVAEISSGV
ITIVFNMIILRLAGNIGVAAYGVVANTSLVAVALFNGIAQGSQPLISDYYGKGLRKNVGSILRMAVVSSLLIAALLILFI
CTFAPFVTSVFNSEHDARLASYAESGLRLYFTGFIFAGINIVGSAILSAVESVKYAFAASIMRGFIAISIFAFALSAAFG
MTGVWLAFPAAEFVTMFIIVKGLRKNYSNYNR

Sequences:

>Translated_432_residues
MKKLFVKYVSQNILGMVGMSLYILADTFFISKAVGSNGITALNLVLPVYNLIFAIGAMIGVGSAIRYVVEKNKGDTSSES
YFFHALLWCIIISVIFILIGIFIPDRLVGLLGGDSAIINTGKNYTRIFMLFTPFFMCNYVCNAFVRNDGAPSIAMCATLF
SSLFNIVFDYILMFPLGLGMEGAALATAISPIIGIMICCIHFCSDKCSVKLKPTVPSVKRLFYSCQVGVSSFVAEISSGV
ITIVFNMIILRLAGNIGVAAYGVVANTSLVAVALFNGIAQGSQPLISDYYGKGLRKNVGSILRMAVVSSLLIAALLILFI
CTFAPFVTSVFNSEHDARLASYAESGLRLYFTGFIFAGINIVGSAILSAVESVKYAFAASIMRGFIAISIFAFALSAAFG
MTGVWLAFPAAEFVTMFIIVKGLRKNYSNYNR
>Mature_432_residues
MKKLFVKYVSQNILGMVGMSLYILADTFFISKAVGSNGITALNLVLPVYNLIFAIGAMIGVGSAIRYVVEKNKGDTSSES
YFFHALLWCIIISVIFILIGIFIPDRLVGLLGGDSAIINTGKNYTRIFMLFTPFFMCNYVCNAFVRNDGAPSIAMCATLF
SSLFNIVFDYILMFPLGLGMEGAALATAISPIIGIMICCIHFCSDKCSVKLKPTVPSVKRLFYSCQVGVSSFVAEISSGV
ITIVFNMIILRLAGNIGVAAYGVVANTSLVAVALFNGIAQGSQPLISDYYGKGLRKNVGSILRMAVVSSLLIAALLILFI
CTFAPFVTSVFNSEHDARLASYAESGLRLYFTGFIFAGINIVGSAILSAVESVKYAFAASIMRGFIAISIFAFALSAAFG
MTGVWLAFPAAEFVTMFIIVKGLRKNYSNYNR

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46592; Mature: 46592

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCC
>Mature Secondary Structure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HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA