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The map label for this gene is yybE [H]

Identifier: 238925190

GI number: 238925190

Start: 2726170

End: 2727051

Strand: Direct

Name: yybE [H]

Synonym: EUBREC_2844

Alternate gene names: 238925190

Gene position: 2726170-2727051 (Clockwise)

Preceding gene: 238925166

Following gene: 238925192

Centisome position: 79.03

GC content: 46.37

Gene sequence:

>882_bases
ATGACACTCAATCAATTAAGTTATTTTTACCAAGCGGCAGTTCTGGAACACTTCAATCAGGCTGCCGAAAAAATGAATAT
CACAGAGCCAAGCCTCAGCCGTTCGATAGCTGCTTTAGAGGACGAGCTTGGCGTCACTTTATTTGAAAAGAGAGGCAGGA
ATGTAATACTGACCAAGGCCGGGGAGATTTTTTTAGAACACGTGTCTACTATTCTGGACGATGTAAAGAGAGCCGAGAGC
AAAATGCACCAGATTGCAACCGACGGCGGTCACATCGATATCGCCTACGTATCACCTCTTGCAAAGGTGTTTATCCCAAC
TATCGTGCGCTCTTTCCTCACCGAAAAGGAAAATAAAAATATCACGTTCAATTTCTTTCAGGACATCACCTCTGTGAATA
TTGAGGGATTAAAAAAAGGCAGGTATGACATAATTTTCGGTTCATACTCGCCAGATGAAAATGGTATTGATTTTGTTCCT
ATTATAAGGCAGGAAATAGTTGCCATACTGCCTCCCGGCCACCCACTGACACTTAAGGATACCATGGAAGCCACTGATTT
CGCTGACTATCCTGTGCTCGGCTATGCCAGACACTCAGGCCTTGGCAAGTACACCAGAAGCTTTTTCAAGAAGCATGATG
TATCGCCAAACTTCATATGTGAGTCACCCGATGAGAACGGCATCGCCTCCCTCGTGGCGCAGGGCTTTGGCATTGCGCTT
GTCGCAGATGTCGATGCAATTCACCGCGATGACATCTGCATACGCCACCTCGTTTCGCATGAGTCATTCTCACACACTGT
ATACATGGGCTACATGACAGGCAAATACCAGCTTCCGGCTATCAAGCGCTTCATAGAGTTTGTGCGGGAAAGCTGCAGCT
AG

Upstream 100 bases:

>100_bases
TAATAGCATTACTGTACTAATCATGTTATAATATGCACAAATTTAGGCTATAATATTTGTAATTCATAGACTGTATCTAT
TATTTTACGGAGATTTATAC

Downstream 100 bases:

>100_bases
GCAGTCTCCTCGATCACAAACCTGATAAATGCCTTCGCAACCGGTGATAAATATCTCTGCTTAAGCGTTGCCAGATACAC
CGCTCTCTCATAAGGAGGAT

Product: transcription activator of glutamate synthase(LysR family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTLNQLSYFYQAAVLEHFNQAAEKMNITEPSLSRSIAALEDELGVTLFEKRGRNVILTKAGEIFLEHVSTILDDVKRAES
KMHQIATDGGHIDIAYVSPLAKVFIPTIVRSFLTEKENKNITFNFFQDITSVNIEGLKKGRYDIIFGSYSPDENGIDFVP
IIRQEIVAILPPGHPLTLKDTMEATDFADYPVLGYARHSGLGKYTRSFFKKHDVSPNFICESPDENGIASLVAQGFGIAL
VADVDAIHRDDICIRHLVSHESFSHTVYMGYMTGKYQLPAIKRFIEFVRESCS

Sequences:

>Translated_293_residues
MTLNQLSYFYQAAVLEHFNQAAEKMNITEPSLSRSIAALEDELGVTLFEKRGRNVILTKAGEIFLEHVSTILDDVKRAES
KMHQIATDGGHIDIAYVSPLAKVFIPTIVRSFLTEKENKNITFNFFQDITSVNIEGLKKGRYDIIFGSYSPDENGIDFVP
IIRQEIVAILPPGHPLTLKDTMEATDFADYPVLGYARHSGLGKYTRSFFKKHDVSPNFICESPDENGIASLVAQGFGIAL
VADVDAIHRDDICIRHLVSHESFSHTVYMGYMTGKYQLPAIKRFIEFVRESCS
>Mature_292_residues
TLNQLSYFYQAAVLEHFNQAAEKMNITEPSLSRSIAALEDELGVTLFEKRGRNVILTKAGEIFLEHVSTILDDVKRAESK
MHQIATDGGHIDIAYVSPLAKVFIPTIVRSFLTEKENKNITFNFFQDITSVNIEGLKKGRYDIIFGSYSPDENGIDFVPI
IRQEIVAILPPGHPLTLKDTMEATDFADYPVLGYARHSGLGKYTRSFFKKHDVSPNFICESPDENGIASLVAQGFGIALV
ADVDAIHRDDICIRHLVSHESFSHTVYMGYMTGKYQLPAIKRFIEFVRESCS

Specific function: Transcriptional Activator Of The Hca Operon For 3- Phenylpropionic Acid Catabolism. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=26.3333333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=23.5294117647059, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=25.1028806584362, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787601, Length=264, Percent_Identity=22.7272727272727, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789204, Length=250, Percent_Identity=22.8, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788296, Length=303, Percent_Identity=24.7524752475248, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081904, Length=196, Percent_Identity=27.5510204081633, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787806, Length=245, Percent_Identity=27.3469387755102, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=300, Percent_Identity=22.6666666666667, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI145693105, Length=202, Percent_Identity=27.2277227722772, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787530, Length=299, Percent_Identity=22.742474916388, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790399, Length=242, Percent_Identity=23.1404958677686, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790262, Length=279, Percent_Identity=23.2974910394265, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32903; Mature: 32772

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNQLSYFYQAAVLEHFNQAAEKMNITEPSLSRSIAALEDELGVTLFEKRGRNVILTKA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHCCCEEEEECH
GEIFLEHVSTILDDVKRAESKMHQIATDGGHIDIAYVSPLAKVFIPTIVRSFLTEKENKN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCC
ITFNFFQDITSVNIEGLKKGRYDIIFGSYSPDENGIDFVPIIRQEIVAILPPGHPLTLKD
EEEEEHHHHHHCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHEEEECCCCCEEEHH
TMEATDFADYPVLGYARHSGLGKYTRSFFKKHDVSPNFICESPDENGIASLVAQGFGIAL
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHCCCCEEE
VADVDAIHRDDICIRHLVSHESFSHTVYMGYMTGKYQLPAIKRFIEFVRESCS
EECCHHHHHCHHHHHHHHHCCCCCCEEEEEEECCCEECHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLNQLSYFYQAAVLEHFNQAAEKMNITEPSLSRSIAALEDELGVTLFEKRGRNVILTKA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHCCCEEEEECH
GEIFLEHVSTILDDVKRAESKMHQIATDGGHIDIAYVSPLAKVFIPTIVRSFLTEKENKN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCC
ITFNFFQDITSVNIEGLKKGRYDIIFGSYSPDENGIDFVPIIRQEIVAILPPGHPLTLKD
EEEEEHHHHHHCCHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHEEEECCCCCEEEHH
TMEATDFADYPVLGYARHSGLGKYTRSFFKKHDVSPNFICESPDENGIASLVAQGFGIAL
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHCCCCEEE
VADVDAIHRDDICIRHLVSHESFSHTVYMGYMTGKYQLPAIKRFIEFVRESCS
EECCHHHHHCHHHHHHHHHCCCCCCEEEEEEECCCEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]