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The map label for this gene is trkG [H]

Identifier: 238925150

GI number: 238925150

Start: 2680381

End: 2681880

Strand: Direct

Name: trkG [H]

Synonym: EUBREC_2803

Alternate gene names: 238925150

Gene position: 2680381-2681880 (Clockwise)

Preceding gene: 238925149

Following gene: 238925151

Centisome position: 77.7

GC content: 43.53

Gene sequence:

>1500_bases
ATGAACACTTCAGTAATTCGATATCTTTTGGGATATATTTTAAAGCTTGAAGGCTTTTTGCTGCTTCTGCCATGTATTGT
TGCCGGTATTTATTATGAAAAAAGCGGCATCTACTTTTTGATTGTTGCACTCATAAGCATAGCTATCGGTTTTATTTTTT
CGGCTAAAAAACCGAGGGATTTTACCTTTTACCTGAAGGAGGGCTGTGCAACAACCGCACTGGGCTGGGTCGTACTGAGT
ATATTCGGCTGTCTGCCGTTTTACATATCAGGAGAGATTCCAAGCTTCACAGATGCTCTTTTTGAGACCATCTCCGGCTT
CACCACGACAGGAGCGAGCATCCTGCCTGAGGTAGAATCACTCTCATATTGCATGAATTTCTGGCGCTGCTTTACTCACT
GGATTGGCGGTATGGGTGTGCTTGTTTTTCTTCTGGCAATCATCCCGCTTTCAGGCGGCAGCAATATCAACCTGATGCGC
GCAGAAAGCCCCGGGCCTTCAGTTGGAAAGCTCGTTCCAAAGATGAAGCATACCGCCAGGCTTTTATACATAATATACTT
TGGTCTTACGACTATGGAGATTATTTTCCTGCTTTTCGGGAAAATGCCTCTGTACGATGCCATCTGTACCTCTCTTGGCA
CAGCCGGAACAGGAGGCTTTGGTATCAAAAACGACAGCTTTTGCGGCTACAATGTTTATCTGCAGTGGGTTGTTACCATA
TTTATGATACTTTTCGGTGTCAATTTCAACGCTTACTACCTGCTTTTCTTCGGTCACATCCGTGACGCACTTAAGGTGGA
AGAGGTCAGATACTATTTCGGCATCATAATAGCCTCCGTTGTAGTCATAAGCGTGAATATCGCGCATATGTGTACCGGTG
TGTTTGACGCAGTCACAAAGGCAGCGTTTCAGGTTGGCTCAATCATCACGACAACCGGATTTTCCAGCACCGATTTCGAC
AGATGGCCTGAGCTTTCAAAGACACTGCTTGTGCTTTTGATGTTCATTGGTGCATGTGCCGGAAGCACCGGCGGCGGTAT
CAAGGTATCTCGTATTGTCATCGCTGTAAAGACAATACTTAAGGAGTTAAATGGCTACATTCACCCAAAGAGTGTGAAAA
AGCTCACATTTGAGCACAAGCCTGTAGACCATGATGTTATCAGGTCAATAAATGTTTATTTCATGACGTATGCCGTCATT
TTTGTTGTTTCAATGCTGCTTGTTTCCGTTGAAAACTATGATTTCACTACCAATTTCACGGCTGTCGCAGCTACATTTAA
CAATATCGGACCGGGTCTTTCTCTGGTCGGTCCGACATGCAATTTCGGCTTTTTTAATAATTTCTCCAAATATATACTGA
TGTTTGACATGCTTGCCGGAAGACTCGAGCTGTTTCCACTGCTCATCCTCTTCCATCCGTCAATCTGGAAGGAATTATTT
ATTCAAGCAGATAAAAAAGTAAAAGGGAATAGAAAGGAGAAACAAAATGTTCGCATGTAA

Upstream 100 bases:

>100_bases
AGGTAATGACTGCATACAAAAAAATGATACTGTCATGATTATAACAACCAATACCGGCTTTACGAATCTTCAGGATATTA
TGGAATAGTGGGGGAATGAT

Downstream 100 bases:

>100_bases
AAATTGCGGTGGAAATGTGAAGTTTGACATCAAATCAGGCCAGTTAGCCTGTGAATACTGTCATTCACTTTTCGACCCTT
ACGCGTACGAGGACAAAACC

Product: potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MNTSVIRYLLGYILKLEGFLLLLPCIVAGIYYEKSGIYFLIVALISIAIGFIFSAKKPRDFTFYLKEGCATTALGWVVLS
IFGCLPFYISGEIPSFTDALFETISGFTTTGASILPEVESLSYCMNFWRCFTHWIGGMGVLVFLLAIIPLSGGSNINLMR
AESPGPSVGKLVPKMKHTARLLYIIYFGLTTMEIIFLLFGKMPLYDAICTSLGTAGTGGFGIKNDSFCGYNVYLQWVVTI
FMILFGVNFNAYYLLFFGHIRDALKVEEVRYYFGIIIASVVVISVNIAHMCTGVFDAVTKAAFQVGSIITTTGFSSTDFD
RWPELSKTLLVLLMFIGACAGSTGGGIKVSRIVIAVKTILKELNGYIHPKSVKKLTFEHKPVDHDVIRSINVYFMTYAVI
FVVSMLLVSVENYDFTTNFTAVAATFNNIGPGLSLVGPTCNFGFFNNFSKYILMFDMLAGRLELFPLLILFHPSIWKELF
IQADKKVKGNRKEKQNVRM

Sequences:

>Translated_499_residues
MNTSVIRYLLGYILKLEGFLLLLPCIVAGIYYEKSGIYFLIVALISIAIGFIFSAKKPRDFTFYLKEGCATTALGWVVLS
IFGCLPFYISGEIPSFTDALFETISGFTTTGASILPEVESLSYCMNFWRCFTHWIGGMGVLVFLLAIIPLSGGSNINLMR
AESPGPSVGKLVPKMKHTARLLYIIYFGLTTMEIIFLLFGKMPLYDAICTSLGTAGTGGFGIKNDSFCGYNVYLQWVVTI
FMILFGVNFNAYYLLFFGHIRDALKVEEVRYYFGIIIASVVVISVNIAHMCTGVFDAVTKAAFQVGSIITTTGFSSTDFD
RWPELSKTLLVLLMFIGACAGSTGGGIKVSRIVIAVKTILKELNGYIHPKSVKKLTFEHKPVDHDVIRSINVYFMTYAVI
FVVSMLLVSVENYDFTTNFTAVAATFNNIGPGLSLVGPTCNFGFFNNFSKYILMFDMLAGRLELFPLLILFHPSIWKELF
IQADKKVKGNRKEKQNVRM
>Mature_499_residues
MNTSVIRYLLGYILKLEGFLLLLPCIVAGIYYEKSGIYFLIVALISIAIGFIFSAKKPRDFTFYLKEGCATTALGWVVLS
IFGCLPFYISGEIPSFTDALFETISGFTTTGASILPEVESLSYCMNFWRCFTHWIGGMGVLVFLLAIIPLSGGSNINLMR
AESPGPSVGKLVPKMKHTARLLYIIYFGLTTMEIIFLLFGKMPLYDAICTSLGTAGTGGFGIKNDSFCGYNVYLQWVVTI
FMILFGVNFNAYYLLFFGHIRDALKVEEVRYYFGIIIASVVVISVNIAHMCTGVFDAVTKAAFQVGSIITTTGFSSTDFD
RWPELSKTLLVLLMFIGACAGSTGGGIKVSRIVIAVKTILKELNGYIHPKSVKKLTFEHKPVDHDVIRSINVYFMTYAVI
FVVSMLLVSVENYDFTTNFTAVAATFNNIGPGLSLVGPTCNFGFFNNFSKYILMFDMLAGRLELFPLLILFHPSIWKELF
IQADKKVKGNRKEKQNVRM

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=489, Percent_Identity=32.719836400818, Blast_Score=241, Evalue=9e-65,
Organism=Escherichia coli, GI48994987, Length=487, Percent_Identity=34.9075975359343, Blast_Score=230, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 55483; Mature: 55483

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSVIRYLLGYILKLEGFLLLLPCIVAGIYYEKSGIYFLIVALISIAIGFIFSAKKPRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FTFYLKEGCATTALGWVVLSIFGCLPFYISGEIPSFTDALFETISGFTTTGASILPEVES
EEHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
LSYCMNFWRCFTHWIGGMGVLVFLLAIIPLSGGSNINLMRAESPGPSVGKLVPKMKHTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LLYIIYFGLTTMEIIFLLFGKMPLYDAICTSLGTAGTGGFGIKNDSFCGYNVYLQWVVTI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FMILFGVNFNAYYLLFFGHIRDALKVEEVRYYFGIIIASVVVISVNIAHMCTGVFDAVTK
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFQVGSIITTTGFSSTDFDRWPELSKTLLVLLMFIGACAGSTGGGIKVSRIVIAVKTIL
HHHHHCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KELNGYIHPKSVKKLTFEHKPVDHDVIRSINVYFMTYAVIFVVSMLLVSVENYDFTTNFT
HHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AVAATFNNIGPGLSLVGPTCNFGFFNNFSKYILMFDMLAGRLELFPLLILFHPSIWKELF
HHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IQADKKVKGNRKEKQNVRM
HHCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MNTSVIRYLLGYILKLEGFLLLLPCIVAGIYYEKSGIYFLIVALISIAIGFIFSAKKPRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
FTFYLKEGCATTALGWVVLSIFGCLPFYISGEIPSFTDALFETISGFTTTGASILPEVES
EEHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
LSYCMNFWRCFTHWIGGMGVLVFLLAIIPLSGGSNINLMRAESPGPSVGKLVPKMKHTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LLYIIYFGLTTMEIIFLLFGKMPLYDAICTSLGTAGTGGFGIKNDSFCGYNVYLQWVVTI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FMILFGVNFNAYYLLFFGHIRDALKVEEVRYYFGIIIASVVVISVNIAHMCTGVFDAVTK
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFQVGSIITTTGFSSTDFDRWPELSKTLLVLLMFIGACAGSTGGGIKVSRIVIAVKTIL
HHHHHCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KELNGYIHPKSVKKLTFEHKPVDHDVIRSINVYFMTYAVIFVVSMLLVSVENYDFTTNFT
HHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AVAATFNNIGPGLSLVGPTCNFGFFNNFSKYILMFDMLAGRLELFPLLILFHPSIWKELF
HHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IQADKKVKGNRKEKQNVRM
HHCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]