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The map label for this gene is mbl [H]

Identifier: 238925133

GI number: 238925133

Start: 2662788

End: 2663786

Strand: Reverse

Name: mbl [H]

Synonym: EUBREC_2786

Alternate gene names: 238925133

Gene position: 2663786-2662788 (Counterclockwise)

Preceding gene: 238925134

Following gene: 238925132

Centisome position: 77.22

GC content: 46.85

Gene sequence:

>999_bases
ATGGTCGGATCAGATATCGGAATCGATTTAGGAACAGCAAGTATACTTGTTTATATAAAAGGAAAGGGTGTTGTGTTAAA
GGAGCCTTCAGTAGTAGCCTTTGACAGGGACACCAACAAGATTAAGGCAATCGGAGAGGAAGCACGCCTCATGCTCGGAA
GGACACCGGGTAATATCGTTGCAGTCAGACCGCTGCGTCAGGGTGTTATCTCAGATTATACAGTTACAGAGAAGATGATC
AAGCACTTCATCCAGAAGGCGCTTGGTAAGAAAAGCTTCAGAAAGCCGCTCGTGAGCGTATGTGTGCCAAGTGGTGTTAC
AGAGGTTGAGAAGAAGGCCGTTGAGGATGCTACATTTGCAGCAGGAGCCAGAGATGTTAAGATTATCGAGGAGCCAATCG
CAGCTGCAATCGGTGCAGGTATTGATATTTCAAAGCCATGCGGAAATATGATAGTAGATATCGGAGGCGGTACATCAGAT
ATAGCAGTTATCTCACTCGGTGGTTCGGTAGTCAGCACATCTATCAAGATAGCCGGAGATGATTTTGATGAGGCAATTGT
CAGATACATGAGAAAGAAGCATAACCTTCTCATCGGAGAGAGAACAGCTGAGGATATCAAAATCAAGATTGGTACATGCT
ACCCTCTCCCACAGCCGGAGACAATTGAGGTAAGAGGAAGAAACCTTGTAACAGGACTTCCAAGGACTATTACAGTCAGC
TCAGAGGAGACAGAGGAAGCACTTCGTGAGGCAACTCTTCAGATAGTTGAGGCAGTGCACTCAGTGCTTGAAAAGACTCC
ACCGGAGCTTGCAGCCGATGTCGCAGACAGAGGAATCGTGCTTACAGGAGGCGGTTCGCTGCTCAGAGGTCTTGAGGAGC
TTATCGAGGAAAAGACCGGCATCAATACAATGACTGCAGAGCAGCCTATGACATGTGTTGCTATCGGTACAGGAAAGTAT
GTAGAGTTCCTTGCAGGCAAGAGAGATGAAGAATTCTAG

Upstream 100 bases:

>100_bases
GACCTTTTTCAAAAAAAAAGTTTGAAAAATGGGATTTATTGTATATAATAAGAGAGTGTATGTGTAAATTTAAAGATATG
GCAGGAAAGGGGCTATTAAA

Downstream 100 bases:

>100_bases
AATATACGTTTTATAACAGGCAGCCGTGAGGGCGATGATATGTCCCTGCATTGCAGGAATGTATTGTCGCTTTTTTGTTA
ATATTGTTACAAATGGGGAT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: Protein mbl [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVGSDIGIDLGTASILVYIKGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIVAVRPLRQGVISDYTVTEKMI
KHFIQKALGKKSFRKPLVSVCVPSGVTEVEKKAVEDATFAAGARDVKIIEEPIAAAIGAGIDISKPCGNMIVDIGGGTSD
IAVISLGGSVVSTSIKIAGDDFDEAIVRYMRKKHNLLIGERTAEDIKIKIGTCYPLPQPETIEVRGRNLVTGLPRTITVS
SEETEEALREATLQIVEAVHSVLEKTPPELAADVADRGIVLTGGGSLLRGLEELIEEKTGINTMTAEQPMTCVAIGTGKY
VEFLAGKRDEEF

Sequences:

>Translated_332_residues
MVGSDIGIDLGTASILVYIKGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIVAVRPLRQGVISDYTVTEKMI
KHFIQKALGKKSFRKPLVSVCVPSGVTEVEKKAVEDATFAAGARDVKIIEEPIAAAIGAGIDISKPCGNMIVDIGGGTSD
IAVISLGGSVVSTSIKIAGDDFDEAIVRYMRKKHNLLIGERTAEDIKIKIGTCYPLPQPETIEVRGRNLVTGLPRTITVS
SEETEEALREATLQIVEAVHSVLEKTPPELAADVADRGIVLTGGGSLLRGLEELIEEKTGINTMTAEQPMTCVAIGTGKY
VEFLAGKRDEEF
>Mature_332_residues
MVGSDIGIDLGTASILVYIKGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIVAVRPLRQGVISDYTVTEKMI
KHFIQKALGKKSFRKPLVSVCVPSGVTEVEKKAVEDATFAAGARDVKIIEEPIAAAIGAGIDISKPCGNMIVDIGGGTSD
IAVISLGGSVVSTSIKIAGDDFDEAIVRYMRKKHNLLIGERTAEDIKIKIGTCYPLPQPETIEVRGRNLVTGLPRTITVS
SEETEEALREATLQIVEAVHSVLEKTPPELAADVADRGIVLTGGGSLLRGLEELIEEKTGINTMTAEQPMTCVAIGTGKY
VEFLAGKRDEEF

Specific function: Not essential for cell viability or sporulation [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=401, Percent_Identity=26.6832917705736, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI24234686, Length=388, Percent_Identity=23.1958762886598, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI5729877, Length=387, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI87082236, Length=329, Percent_Identity=53.7993920972644, Blast_Score=355, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI17507981, Length=400, Percent_Identity=26.25, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17534015, Length=402, Percent_Identity=24.1293532338308, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534013, Length=402, Percent_Identity=24.1293532338308, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17568549, Length=355, Percent_Identity=26.4788732394366, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534771, Length=361, Percent_Identity=25.7617728531856, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322426, Length=388, Percent_Identity=26.5463917525773, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641406, Length=399, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641408, Length=399, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641402, Length=399, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641404, Length=399, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 35426; Mature: 35426

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGSDIGIDLGTASILVYIKGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIV
CCCCCCCCEECCEEEEEEECCCEEEEECCCEEEEECCCCHHHHHCHHHHEEEECCCCCEE
AVRPLRQGVISDYTVTEKMIKHFIQKALGKKSFRKPLVSVCVPSGVTEVEKKAVEDATFA
EECHHHHCHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGARDVKIIEEPIAAAIGAGIDISKPCGNMIVDIGGGTSDIAVISLGGSVVSTSIKIAGD
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEEEEECC
DFDEAIVRYMRKKHNLLIGERTAEDIKIKIGTCYPLPQPETIEVRGRNLVTGLPRTITVS
CHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEECCCCCCCEEEECCCEEEECCCCEEEEC
SEETEEALREATLQIVEAVHSVLEKTPPELAADVADRGIVLTGGGSLLRGLEELIEEKTG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCC
INTMTAEQPMTCVAIGTGKYVEFLAGKRDEEF
CCCEECCCCEEEEEECCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MVGSDIGIDLGTASILVYIKGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIV
CCCCCCCCEECCEEEEEEECCCEEEEECCCEEEEECCCCHHHHHCHHHHEEEECCCCCEE
AVRPLRQGVISDYTVTEKMIKHFIQKALGKKSFRKPLVSVCVPSGVTEVEKKAVEDATFA
EECHHHHCHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGARDVKIIEEPIAAAIGAGIDISKPCGNMIVDIGGGTSDIAVISLGGSVVSTSIKIAGD
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEEEEECC
DFDEAIVRYMRKKHNLLIGERTAEDIKIKIGTCYPLPQPETIEVRGRNLVTGLPRTITVS
CHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEECCCCCCCEEEECCCEEEECCCCEEEEC
SEETEEALREATLQIVEAVHSVLEKTPPELAADVADRGIVLTGGGSLLRGLEELIEEKTG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCC
INTMTAEQPMTCVAIGTGKYVEFLAGKRDEEF
CCCEECCCCEEEEEECCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836311; 9384377; 10568751; 9353933 [H]